Pou4f2 (POU class 4 homeobox 2) - Rat Genome Database

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Gene: Pou4f2 (POU class 4 homeobox 2) Ictidomys tridecemlineatus
Analyze
Symbol: Pou4f2
Name: POU class 4 homeobox 2
RGD ID: 12483552
Description: ENCODES a protein that exhibits chromatin binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); INVOLVED IN axon extension (ortholog); axon guidance (ortholog); axonogenesis (ortholog); PARTICIPATES IN p53 signaling pathway; FOUND IN cytoplasm (ortholog); euchromatin (ortholog); nuclear speck (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: POU domain, class 4, transcription factor 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530145,265,697 - 45,274,468 (-)NCBI
SpeTri2.0NW_0049365352,705,184 - 2,711,785 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
axon extension  (ISO)
axon guidance  (ISO)
axonogenesis  (ISO)
cellular response to cytokine stimulus  (ISO)
cellular response to estradiol stimulus  (ISO)
cellular response to insulin stimulus  (ISO)
cellular response to oxygen levels  (ISO)
dorsal root ganglion development  (ISO)
heart development  (ISO)
intracellular estrogen receptor signaling pathway  (ISO)
intrinsic apoptotic signaling pathway by p53 class mediator  (ISO)
MAPK cascade  (ISO)
negative regulation of adipose tissue development  (ISO)
negative regulation of amacrine cell differentiation  (ISO)
negative regulation of cell differentiation  (ISO)
negative regulation of DNA-binding transcription factor activity  (ISO)
negative regulation of transcription by RNA polymerase II  (ISO)
neuromuscular process controlling balance  (ISO)
neuron differentiation  (ISO)
positive regulation of axon extension  (ISO)
positive regulation of cardiac muscle cell apoptotic process  (ISO)
positive regulation of cell differentiation  (ISO)
positive regulation of glucose import  (ISO)
positive regulation of osteoclast differentiation  (ISO)
positive regulation of programmed cell death  (ISO)
positive regulation of transcription by RNA polymerase II  (ISO)
positive regulation of transcription regulatory region DNA binding  (ISO)
regulation of DNA-binding transcription factor activity  (ISO)
regulation of gene expression  (ISO)
regulation of retinal ganglion cell axon guidance  (ISO)
retina development in camera-type eye  (ISO)
retinal ganglion cell axon guidance  (ISO)
sensory perception of sound  (ISO)
spermatogenesis  (ISO)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
Pou4f2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530145,265,697 - 45,274,468 (-)NCBI
SpeTri2.0NW_0049365352,705,184 - 2,711,785 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
POU4F2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl4146,638,893 - 146,642,474 (+)EnsemblGRCh38hg38GRCh38
GRCh384146,638,893 - 146,642,474 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh374147,560,045 - 147,563,626 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364147,779,495 - 147,783,073 (+)NCBINCBI36hg18NCBI36
Build 344147,917,692 - 147,921,228NCBI
Celera4144,880,585 - 144,884,163 (+)NCBI
Cytogenetic Map4q31.22NCBI
HuRef4143,287,267 - 143,290,856 (+)NCBIHuRef
CHM1_14147,537,342 - 147,540,923 (+)NCBICHM1_1
Pou4f2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39879,159,638 - 79,163,276 (-)NCBIGRCm39mm39
GRCm39 Ensembl879,159,639 - 79,163,274 (-)Ensembl
GRCm38878,433,009 - 78,436,647 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl878,433,010 - 78,436,645 (-)EnsemblGRCm38mm10GRCm38
MGSCv37880,956,908 - 80,960,551 (-)NCBIGRCm37mm9NCBIm37
MGSCv36881,329,081 - 81,332,724 (-)NCBImm8
Celera882,709,269 - 82,712,912 (-)NCBICelera
Cytogenetic Map8C1NCBI
Pou4f2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21929,486,686 - 29,490,327 (+)NCBI
Rnor_6.0 Ensembl1933,160,180 - 33,163,821 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01933,160,180 - 33,163,821 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01944,051,763 - 44,055,404 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41931,388,907 - 31,392,548 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11931,395,364 - 31,395,583 (+)NCBI
Celera1928,985,198 - 28,988,839 (+)NCBICelera
Cytogenetic Map19q11NCBI
Pou4f2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554282,324,834 - 2,329,205 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554282,325,775 - 2,329,122 (+)NCBIChiLan1.0ChiLan1.0
POU4F2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.14150,626,392 - 150,629,961 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4150,626,392 - 150,629,961 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v04138,969,157 - 138,972,730 (+)NCBIMhudiblu_PPA_v0panPan3
POU4F2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11545,030,818 - 45,034,446 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1545,031,094 - 45,032,784 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1545,426,310 - 45,427,991 (+)NCBI
ROS_Cfam_1.01545,704,140 - 45,705,824 (+)NCBI
UMICH_Zoey_3.11544,976,012 - 44,977,696 (+)NCBI
UNSW_CanFamBas_1.01545,068,621 - 45,070,311 (+)NCBI
UU_Cfam_GSD_1.01545,333,613 - 45,335,300 (+)NCBI
POU4F2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl882,044,644 - 82,046,307 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1882,044,443 - 82,046,377 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2887,200,440 - 87,201,609 (-)NCBISscrofa10.2Sscrofa10.2susScr3
POU4F2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1793,150,105 - 93,160,977 (+)NCBI
ChlSab1.1 Ensembl793,150,186 - 93,151,857 (+)Ensembl
Pou4f2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248535,446,575 - 5,448,704 (+)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_005327540   ⟹   XP_005327597
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440530145,270,033 - 45,273,674 (-)NCBI
SpeTri2.0NW_0049365352,705,184 - 2,711,011 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021727884   ⟹   XP_021583559
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0NW_0049365352,708,504 - 2,711,785 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021727885   ⟹   XP_021583560
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440530145,270,033 - 45,274,468 (-)NCBI
SpeTri2.0NW_0049365352,708,504 - 2,711,785 (-)NCBI
Sequence:
RefSeq Acc Id: XR_005737337
RefSeq Status:
Type: NON-CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440530145,265,697 - 45,273,674 (-)NCBI
Protein Sequences
Protein RefSeqs XP_005327597 (Get FASTA)   NCBI Sequence Viewer  
  XP_021583560 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005327597   ⟸   XM_005327540
- UniProtKB: I3NAE4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021583560   ⟸   XM_021727885
- Sequence:
RefSeq Acc Id: XP_021583559   ⟸   XM_021727884
- Sequence:
Protein Domains
Homeobox   POU-specific


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000021113 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000021341 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000023796 UniProtKB/TrEMBL
Gene3D-CATH 1.10.260.40 UniProtKB/TrEMBL
InterPro Cro/C1-type_HTH UniProtKB/TrEMBL
  Homeobox-like UniProtKB/TrEMBL
  Homeobox_CS UniProtKB/TrEMBL
  Homeobox_dom UniProtKB/TrEMBL
  Lambda_DNA-bd_dom UniProtKB/TrEMBL
  POU UniProtKB/TrEMBL
  POU_dom UniProtKB/TrEMBL
NCBI Gene Pou4f2 ENTREZGENE
Pfam Homeobox UniProtKB/TrEMBL
  Pou UniProtKB/TrEMBL
PRINTS POUDOMAIN UniProtKB/TrEMBL
PROSITE HOMEOBOX_1 UniProtKB/TrEMBL
  HOMEOBOX_2 UniProtKB/TrEMBL
  POU_1 UniProtKB/TrEMBL
  POU_2 UniProtKB/TrEMBL
  POU_3 UniProtKB/TrEMBL
SMART HOX UniProtKB/TrEMBL
  POU UniProtKB/TrEMBL
Superfamily-SCOP SSF46689 UniProtKB/TrEMBL
  SSF47413 UniProtKB/TrEMBL
UniProt I3NAE4 ENTREZGENE, UniProtKB/TrEMBL