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Gene: Ramp3 (receptor (calcitonin) activity modifying protein 3) Mus musculus

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Symbol:

Ramp3

Name:

receptor (calcitonin) activity modifying protein 3

RGD ID:

62165

MGI Page

MGI

Description:

Enables coreceptor activity. Involved in G protein-coupled receptor signaling pathway involved in heart process and cellular response to estradiol stimulus. Acts upstream of or within G protein-coupled receptor signaling pathway. Located in plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; heart; liver; and lung. Orthologous to human RAMP3 (receptor activity modifying protein 3).

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

AI850306; receptor activity-modifying protein 3

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	6,608,507 - 6,627,478 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	6,608,521 - 6,627,475 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	11	6,658,506 - 6,677,478 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	6,658,521 - 6,677,475 (+)	Ensembl			mm10	GRCm38
MGSCv37	11	6,558,536 - 6,577,478 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	11	6,558,536 - 6,577,478 (+)	NCBI		MGSCv36	mm8
Celera	11	18,979,836 - 18,982,575 (-)	NCBI		Celera
Cytogenetic Map	11	A1	NCBI
cM Map	11	4.61	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

colorectal cancer (ISO)

Lymphatic Metastasis (ISO)

pleomorphic xanthoastrocytoma (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(S)-nicotine (EXP,ISO)

1,2-dimethylhydrazine (EXP)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (EXP,ISO)

17beta-estradiol 3-benzoate (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4,6-trinitrobenzenesulfonic acid (ISO)

2,4-dibromophenyl 2,4,5-tribromophenyl ether (EXP)

2-palmitoylglycerol (ISO)

3,3',5,5'-tetrabromobisphenol A (EXP)

4,4'-sulfonyldiphenol (EXP)

4-hydroxyphenyl retinamide (EXP)

5-aza-2'-deoxycytidine (EXP)

6-propyl-2-thiouracil (ISO)

acetamide (ISO)

acrylamide (ISO)

aldehydo-D-glucose (EXP)

alpha-Zearalanol (ISO)

amitrole (ISO)

ammonium chloride (ISO)

amphotericin B (ISO)

atrazine (ISO)

Azoxymethane (EXP)

benzo[a]pyrene (EXP,ISO)

benzo[b]fluoranthene (EXP)

Benzo[k]fluoranthene (EXP)

bisphenol A (EXP,ISO)

buta-1,3-diene (EXP)

calciol (ISO)

carbon nanotube (EXP)

chloroprene (EXP)

chrysene (EXP)

D-glucose (EXP)

dextran sulfate (EXP)

dibenz[a,h]anthracene (EXP)

dibutyl phthalate (ISO)

dioxygen (EXP)

ethanol (EXP)

furan (ISO)

glucose (EXP)

hydralazine (ISO)

hydrochlorothiazide (ISO)

hydrogen cyanide (EXP)

indole-3-methanol (ISO)

inulin (EXP)

isoprenaline (ISO)

methimazole (ISO)

methoxychlor (ISO)

morphine (EXP)

N(gamma)-nitro-L-arginine methyl ester (ISO)

nicotine (EXP,ISO)

nitric oxide (ISO)

oxaliplatin (ISO)

perfluorohexanesulfonic acid (EXP)

perfluorooctane-1-sulfonic acid (EXP)

perfluorooctanoic acid (ISO)

phenylephrine (ISO)

pirinixic acid (EXP)

potassium cyanide (EXP)

progesterone (EXP)

sulfadimethoxine (ISO)

testosterone (ISO)

tetrachloromethane (ISO)

tetraphene (EXP)

titanium dioxide (EXP)

topotecan (ISO)

trichloroethene (ISO)

troglitazone (EXP)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adenylate cyclase-activating G protein-coupled receptor signaling pathway (IEA,ISO)

adrenomedullin receptor signaling pathway (IEA,ISO)

amylin receptor 3 signaling pathway (IEA,ISO)

amylin receptor signaling pathway (IEA,ISO)

calcium ion transport (IBA,IEA,ISO)

cellular response to estradiol stimulus (IDA)

cellular response to hormone stimulus (IBA)

cross-receptor inhibition within G protein-coupled receptor heterodimer (ISO)

G protein-coupled receptor signaling pathway (IBA,IPI)

G protein-coupled receptor signaling pathway involved in heart process (IMP)

intracellular protein transport (IEA)

positive regulation of calcium-mediated signaling (IEA,ISO)

positive regulation of cAMP/PKA signal transduction (IEA,ISO)

positive regulation of ERK1 and ERK2 cascade (IEA,ISO)

positive regulation of gene expression (IEA,ISO)

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction (IEA,ISO)

positive regulation of protein localization to plasma membrane (IEA,ISO,ISS)

positive regulation of receptor recycling (IEA,ISO)

protein localization to plasma membrane (IBA,IEA,ISO)

protein transport (IBA,IEA,ISO)

receptor internalization (IBA,IEA,ISO)

regulation of G protein-coupled receptor signaling pathway (IEA)

response to amyloid-beta (IEA,ISO)

Cellular Component

adrenomedullin receptor complex (IEA,ISO)

amylin receptor complex 3 (IEA,ISO)

cell surface (IBA,IEA,ISO)

lysosome (IEA,ISO)

membrane (IEA)

plasma membrane (IDA,IEA,ISO)

receptor complex (IBA,IEA,ISO)

Molecular Function

adrenomedullin receptor activity (IEA,ISO)

amylin receptor activity (IEA,ISO)

coreceptor activity (IBA,IDA,IEA,ISO)

protein binding (ISO)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

decreased body weight (IAGP)

References

References - curated

#	Reference Title	Reference Citation
1.	Adrenomedullin production is increased in colorectal adenocarcinomas; its relation to matrix metalloproteinase-9.	Hikosaka T, etal., Peptides. 2011 Sep;32(9):1825-31. doi: 10.1016/j.peptides.2011.07.012. Epub 2011 Aug 3.
2.	Functional annotation of a full-length mouse cDNA collection.	Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
3.	Electronic Transfer of Homolog Data	MGD and Homologene mouse data transfer
4.	MGDs mouse GO annotations	MGD data from the GO Consortium
5.	Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.	Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6.	Mouse MP Annotation Import Pipeline	RGD automated import pipeline
7.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:8889548	PMID:10349636	PMID:10777702	PMID:10828067	PMID:10854696	PMID:11042159	PMID:11060459	PMID:11076861	PMID:11854283	PMID:12477932	PMID:14610273	PMID:15489334
PMID:16141072	PMID:16141073	PMID:16284245	PMID:16602821	PMID:17470425	PMID:18097473	PMID:18255060	PMID:18287559	PMID:18981183	PMID:21267068	PMID:21873635	PMID:22100352
PMID:22563471	PMID:23674134	PMID:25264174	PMID:27668656	PMID:27940069	PMID:29467172	PMID:30385288	PMID:30728831	PMID:31754214	PMID:31881259	PMID:33385343	PMID:33545715
PMID:33905587	PMID:35628521	PMID:36971701	PMID:37528140	PMID:38012983	PMID:39415015

Genomics

Comparative Map Data

Ramp3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	6,608,507 - 6,627,478 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	6,608,521 - 6,627,475 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	11	6,658,506 - 6,677,478 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	6,658,521 - 6,677,475 (+)	Ensembl			mm10	GRCm38
MGSCv37	11	6,558,536 - 6,577,478 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	11	6,558,536 - 6,577,478 (+)	NCBI		MGSCv36	mm8
Celera	11	18,979,836 - 18,982,575 (-)	NCBI		Celera
Cytogenetic Map	11	A1	NCBI
cM Map	11	4.61	NCBI

RAMP3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	7	45,157,791 - 45,184,250 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	7	45,157,791 - 45,186,302 (+)	Ensembl			hg38	GRCh38
GRCh37	7	45,197,390 - 45,223,849 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	45,163,892 - 45,190,374 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	7	44,970,638 - 44,997,087	NCBI
Celera	7	45,296,201 - 45,322,683 (+)	NCBI		Celera
Cytogenetic Map	7	p13	NCBI
HuRef	7	45,081,154 - 45,107,455 (+)	NCBI		HuRef
CHM1_1	7	45,201,027 - 45,227,508 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	7	45,318,568 - 45,345,028 (+)	NCBI		T2T-CHM13v2.0
CRA_TCAGchr7v2	7	45,236,530 - 45,263,012 (+)	NCBI

Ramp3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	85,741,314 - 85,758,813 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	14	85,755,211 - 85,758,818 (+)	Ensembl				GRCr8
mRatBN7.2	14	81,527,404 - 81,544,905 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	81,527,385 - 81,544,902 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	14	85,928,688 - 85,946,185 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	87,168,498 - 87,186,001 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	83,618,093 - 83,635,590 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	86,922,223 - 86,939,722 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	86,922,223 - 86,939,719 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	14	80,555,482 - 80,572,981 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	14	87,417,290 - 87,434,789 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	14	80,409,008 - 80,426,508 (+)	NCBI		Celera
RGSC_v3.1	14	87,436,434 - 87,453,933 (+)	NCBI
Cytogenetic Map	14	q21	NCBI

Ramp3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955456	7,159,845 - 7,168,792 (-)	Ensembl
ChiLan1.0	NW_004955456	7,159,845 - 7,168,718 (-)	NCBI	ChiLan1.0	ChiLan1.0

RAMP3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	6	50,070,783 - 50,097,555 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	7	98,395,524 - 98,422,292 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	7	45,871,687 - 45,898,159 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	7	45,937,607 - 45,964,088 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	7	45,937,607 - 45,966,041 (+)	Ensembl			panPan2	panpan1.1

RAMP3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Dog10K_Boxer_Tasha	16	2,664,601 - 2,679,402 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	16	14,181,470 - 14,196,274 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	16	14,181,436 - 14,196,296 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UNSW_CanFamBas_1.0	16	13,814,391 - 13,829,193 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	16	13,793,847 - 13,808,648 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Ramp3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	100,765,846 - 100,789,731 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936478	19,977,539 - 20,004,838 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936478	19,977,618 - 20,001,366 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RAMP3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	18	50,319,797 - 50,366,739 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	18	50,319,795 - 50,366,757 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	18	55,155,083 - 55,174,055 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RAMP3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	21	13,494,981 - 13,521,141 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666062	9,009,778 - 9,035,756 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ramp3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624740	7,241,296 - 7,249,410 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624740	7,240,841 - 7,249,313 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Variants

Variants in Ramp3
617 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	393
Count of miRNA genes:	323
Interacting mature miRNAs:	355
Transcripts:	ENSMUST00000045374, ENSMUST00000139540
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300599	Cocrb11_m	cocaine related behavior 11 (mouse)			Not determined		11	2670355	36671472	Mouse
26884446	Sklq10_m	skull length QTL 10, 10 week (mouse)					11	3250000	62890826	Mouse
1300661	Lmr6_m	leishmaniasis resistance 6 (mouse)			Not determined		11	1	25976374	Mouse
13208559	Wght10_m	weight 10 (mouse)					11	3950000	88890826	Mouse
13208558	Lgth12_m	body length 12 (mouse)					11	3950000	94890826	Mouse
27095925	Pglq5_m	pelvic girdle length QTL 5, 5 week (mouse)					11	3250000	19750000	Mouse
27226741	Metcl5_m	metatarsal-calcaneal length 5, 5 week (mouse)					11	4650000	46290827	Mouse
1357722	Vtbt11_m	vertebral trabecular bone trait 11 (mouse)			Not determined		11	1	23880487	Mouse
27226735	Metcl16_m	metatarsal-calcaneal length 16, 16 week (mouse)					11	5250000	35090827	Mouse
10044008	Hbnr15_m	Heligmosomoides bakeri nematode resistance 15 (mouse)			Not determined		11	227052	34227232	Mouse
27226798	Scvln18_m	sacral vertebrae length 2, 16 week (mouse)					11	3250000	60690826	Mouse
27095919	Pglq10_m	pelvic girdle length QTL 10, 10 week (mouse)					11	3250000	18450000	Mouse
1300768	Tshp9_m	tooth shape 9 (mouse)			Not determined		11	1	25976374	Mouse
10053676	Eae44a_m	experimental allergic encephalomyelitis susceptibility 44a (mouse)			Not determined		11	4507896	21379532	Mouse
1301765	Skull15_m	skull morphology 15 (mouse)			Not determined		11	1	25976374	Mouse
27095914	Pglq16_m	pelvic girdle length QTL 16, 16 week (mouse)					11	3250000	18150000	Mouse
27095909	Scvln6_m	sacral vertebrae length 2, 5 week (mouse)					11	3250000	44090827	Mouse
27095904	Scvln12_m	sacral vertebrae length 2, 10 week (mouse)					11	3250000	34495048	Mouse
26884453	Sklq16_m	skull length QTL 16, 16 week (mouse)					11	3250000	72690826	Mouse

Markers in Region

AI850306

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	11	6,677,250 - 6,677,399	UniSTS	GRCm38
MGSCv37	11	6,577,253 - 6,577,402	UniSTS	GRCm37
Celera	11	18,979,912 - 18,980,061	UniSTS
Cytogenetic Map	11	A1	UniSTS
cM Map	11	2.1	UniSTS
Whitehead/MRC_RH	11	38.46	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_019511	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006514761	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AF146524	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF209907	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AJ250491	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK005513	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AL603787	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC024765	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSMUST00000045374 ⟹ ENSMUSP00000047518

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	11	6,608,521 - 6,627,475 (+)	Ensembl
GRCm38.p6 Ensembl	11	6,658,521 - 6,677,475 (+)	Ensembl

Ensembl Acc Id:

ENSMUST00000139540

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	11	6,608,565 - 6,627,472 (+)	Ensembl
GRCm38.p6 Ensembl	11	6,658,565 - 6,677,472 (+)	Ensembl

RefSeq Acc Id:

NM_019511 ⟹ NP_062384

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	11	6,608,533 - 6,627,475 (+)	NCBI
GRCm38	11	6,658,533 - 6,677,475 (+)	NCBI
MGSCv37	11	6,558,536 - 6,577,478 (+)	RGD
Celera	11	18,979,836 - 18,982,575 (-)	RGD
cM Map	11		ENTREZGENE

Sequence:

show sequence

ATGTCGCTGTTGCTGCAAGCCGGCTGCATCTTAGTTGGCCATGAAGACCCCAGCACAGCGGCTG
CACCTTCTTCCACTGTTGTTGCTGCTTTGTGGTGAGTGTGCCCAGGTATGCGGCTGCAACGAGA
CAGGGATGCTGGAGAGGCTGCCTCGCTGTGGGAAAGCCTTCGCTGACATGATGCAGAAGGTGGC
TGTCTGGAAGTGGTGCAACCTGTCGGAGTTCATCGTGTATTATGAAAGCTTCACTAACTGCACC
GAGATGGAGACCAACATCATGGGCTGCTACTGGCCCAACCCGCTGGCCCAGAGCTTCATCACTG
GAATCCACAGGCAGTTCTTTTCCAACTGCACGGTGGACAGGACCCACTGGGAAGACCCCCCGGA
TGAAGTACTCATCCCACTGATCGCGGTTCCTGTCGTGCTGACTGTGGCTATGGCTGGCCTGGTG
GTGTGGCGCAGCAAGCACACTGATCGGCTGCTGTGAGGATCTGCTGGATGGAGGGCCATGCCTG
GCAGGCTGGGAGAATGTTGCTCAGAGCTCTGAGAGCTGGCAGACTCGGCTTCTGTCTGGTTTGC
TTTGGCCACACCCTACCTGGCCATGCCAAAGTCCTCCTGACCAGGCTGGTGTGGCCCTTGCTGT
CTAGCCTGCCGCCTGCTGGGGTTCAGATTGTCCATACTTTGCTCTTTCTTGGGCTAGTGGAAGA
AAGTGACAAATCCCAAGTTTGTGGACCAGGCATGGAAATCAACTGTTGCTGAGCCCCGCTCCCC
AGGCTCGGTTCCCTAGTTTCTAGCCGTTTCTTGGCAGAGTCTTGCTCAGCCTGAACCCCGCCCC
AGGTCCTGACCCATTTCTAGTCCTGACCCTGACCCCTGCTACACTTGGCCAGAGAGGGCAGGCA
AGGTCATCTGGAAGATGTGGACGCCCCCCCGCCTCTGTTCAAGAGACTGAGCACATCATTTATC
AGACATGAAGGATAGCCTGGGGTCATTAGGAGCCACGTGTGACCTACTGACCCACCTGCCTGTC
CTCTCTGTGATCTGTCACGATTCTGTGTCCAGTGTGGGCTGGAGCTGTGGCTTGTTTAGCCCTT
CAAAGACACCTACCCTGCAGGTAGAGCGTGAACCTCCTTCTTGAGGGGTATTCCTGGGAGTGGG
GCGCACTGAGTGTGCTCAAGGGTTCTGTCTGCTGATGTCAGTTCTTTTTGATTAAAGTGTCTCC
TTACA

hide sequence

RefSeq Acc Id:

XM_006514761 ⟹ XP_006514824

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	11	6,608,507 - 6,627,478 (+)	NCBI
GRCm38	11	6,658,506 - 6,677,478 (+)	NCBI

Sequence:

show sequence

TCCCGCCCCAAGCCTCTTACCTCCGAATGTCGCTGTTGCTGCAAGCCGGCTGCATCTTAGTTGG
CCATGAAGACCCCAGCACAGCGGCTGCACCTTCTTCCACTGTTGTTGCTGCTTTGTGGTTCCTT
GCTGCCGTCCCTTCCCCGTGAGCTCAACTGAACCATTTCCTCCTCTAAAGTTGGTTTTGGACGG
TGATTACCACAGCAACAGACCAGCAAACTAGGACACCTGTGTAATTATTCCCTTTGAAGTACTT
CAGAGCCTAGAGGTGAGTGTGCCCAGGTATGCGGCTGCAACGAGACAGGGATGCTGGAGAGGCT
GCCTCGCTGTGGGAAAGCCTTCGCTGACATGATGCAGAAGGTGGCTGTCTGGAAGTGGTGCAAC
CTGTCGGAGTTCATCGTGTATTATGAAAGCTTCACTAACTGCACCGAGATGGAGACCAACATCA
TGGGCTGCTACTGGCCCAACCCGCTGGCCCAGAGCTTCATCACTGGAATCCACAGGCAGTTCTT
TTCCAACTGCACGGTGGACAGGACCCACTGGGAAGACCCCCCGGATGAAGTACTCATCCCACTG
ATCGCGGTTCCTGTCGTGCTGACTGTGGCTATGGCTGGCCTGGTGGTGTGGCGCAGCAAGCACA
CTGATCGGCTGCTGTGAGGATCTGCTGGATGGAGGGCCATGCCTGGCAGGCTGGGAGAATGTTG
CTCAGAGCTCTGAGAGCTGGCAGACTCGGCTTCTGTCTGGTTTGCTTTGGCCACACCCTACCTG
GCCATGCCAAAGTCCTCCTGACCAGGCTGGTGTGGCCCTTGCTGTCTAGCCTGCCGCCTGCTGG
GGTTCAGATTGTCCATACTTTGCTCTTTCTTGGGCTAGTGGAAGAAAGTGACAAATCCCAAGTT
TGTGGACCAGGCATGGAAATCAACTGTTGCTGAGCCCCGCTCCCCAGGCTCGGTTCCCTAGTTT
CTAGCCGTTTCTTGGCAGAGTCTTGCTCAGCCTGAACCCCGCCCCAGGTCCTGACCCATTTCTA
GTCCTGACCCTGACCCCTGCTACACTTGGCCAGAGAGGGCAGGCAAGGTCATCTGGAAGATGTG
GACGCCCCCCCGCCTCTGTTCAAGAGACTGAGCACATCATTTATCAGACATGAAGGATAGCCTG
GGGTCATTAGGAGCCACGTGTGACCTACTGACCCACCTGCCTGTCCTCTCTGTGATCTGTCACG
ATTCTGTGTCCAGTGTGGGCTGGAGCTGTGGCTTGTTTAGCCCTTCAAAGACACCTACCCTGCA
GGTAGAGCGTGAACCTCCTTCTTGAGGGGTATTCCTGGGAGTGGGGCGCACTGAGTGTGCTCAA
GGGTTCTGTCTGCTGATGTCAGTTCTTTTTGATTAAAGTGTCTCCTTACACGT

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Protein Sequences


Protein RefSeqs	NP_062384	(Get FASTA)	NCBI Sequence Viewer
	XP_006514824	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAD35020	(Get FASTA)	NCBI Sequence Viewer
	AAF21039	(Get FASTA)	NCBI Sequence Viewer
	AAH24765	(Get FASTA)	NCBI Sequence Viewer
	CAB59513	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000047518
	ENSMUSP00000047518.8
GenBank Protein	Q9WUP1	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_062384 ⟸ NM_019511
- Peptide Label:	precursor
- UniProtKB:	Q5SWP4 (UniProtKB/Swiss-Prot), Q9WUP1 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MKTPAQRLHLLPLLLLLCGECAQVCGCNETGMLERLPRCGKAFADMMQKVAVWKWCNLSEFIVY YESFTNCTEMETNIMGCYWPNPLAQSFITGIHRQFFSNCTVDRTHWEDPPDEVLIPLIAVPVVL TVAMAGLVVWRSKHTDRLL hide sequence

RefSeq Acc Id:	XP_006514824 ⟸ XM_006514761
- Peptide Label:	isoform X1
- Sequence:	show sequence MLERLPRCGKAFADMMQKVAVWKWCNLSEFIVYYESFTNCTEMETNIMGCYWPNPLAQSFITGI HRQFFSNCTVDRTHWEDPPDEVLIPLIAVPVVLTVAMAGLVVWRSKHTDRLL hide sequence

Ensembl Acc Id:

ENSMUSP00000047518 ⟸ ENSMUST00000045374

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9WUP1-F1-model_v2	AlphaFold	Q9WUP1	1-147	view protein structure

Promoters

RGD ID:

8673926

Promoter ID:

EPDNEW_M14993

Type:

initiation region

Name:

Ramp3_1

Description:

Mus musculus receptor activity modifying protein 3 , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	11	6,658,525 - 6,658,585	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:1860292	AgrOrtholog
Ensembl Genes	ENSMUSG00000041046	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSMUST00000045374	ENTREZGENE
	ENSMUST00000045374.8	UniProtKB/Swiss-Prot
	ENSMUST00000139540	ENTREZGENE
Gene3D-CATH	1.10.150.510	UniProtKB/Swiss-Prot
InterPro	RAMP	UniProtKB/Swiss-Prot
	RAMP_sf	UniProtKB/Swiss-Prot
KEGG Report	mmu:56089	UniProtKB/Swiss-Prot
MGD	MGI:1860292	ENTREZGENE
NCBI Gene	56089	ENTREZGENE
PANTHER	PTHR14076	UniProtKB/Swiss-Prot
	RECEPTOR ACTIVITY-MODIFYING PROTEIN 3	UniProtKB/Swiss-Prot
Pfam	RAMP	UniProtKB/Swiss-Prot
PhenoGen	Ramp3	PhenoGen
UniProt	Q5SWP4	ENTREZGENE
	Q9WUP1	ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary	Q5SWP4	UniProtKB/Swiss-Prot

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar

Mammalian Phenotype