Kat5 (K(lysine) acetyltransferase 5) - Rat Genome Database

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Gene: Kat5 (K(lysine) acetyltransferase 5) Mus musculus
Analyze
Symbol: Kat5
Name: K(lysine) acetyltransferase 5
RGD ID: 1550306
MGI Page MGI
Description: Enables chromatin binding activity; histone acetyltransferase activity; and transcription coactivator activity. Involved in several processes, including nervous system development; positive regulation of regulatory T cell differentiation; and sperm DNA condensation. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Part of NuA4 histone acetyltransferase complex and transcription regulator complex. Is expressed in several structures, including central nervous system; eye; genitourinary system; hemolymphoid system gland; and limb. Orthologous to human KAT5 (lysine acetyltransferase 5).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 60 kDa Tat-interactive protein; 60kDa; AI839539; CPLA2; histone acetyltransferase HTATIP; histone acetyltransferase KAT5; HIV-1 tat interactive protein 1, 60 kDa homolog; HIV-1 tat interactive protein 1, homolog; HIV-1 tat interactive protein, homolog; Hta; Htatip; Htatip1; lysine acetyltransferase 5; MGC117972; mHTATIP/CPLA2; PLIP; Tat-interactive protein-60; Tip; Tip55; Tip60
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39195,653,042 - 5,661,584 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl195,653,042 - 5,660,265 (-)EnsemblGRCm39 Ensembl
GRCm38195,603,014 - 5,611,556 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl195,603,014 - 5,610,237 (-)EnsemblGRCm38mm10GRCm38
MGSCv37195,603,418 - 5,610,029 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36195,603,418 - 5,610,029 (-)NCBIMGSCv36mm8
Celera195,473,388 - 5,479,999 (-)NCBICelera
Cytogenetic Map19ANCBI
cM Map194.34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
apoptotic process  (IDA)
cellular response to estradiol stimulus  (IEA,ISO)
cellular response to glucose starvation  (ISO,ISS)
cellular response to glucose stimulus  (IMP)
cellular response to hydrogen peroxide  (ISO)
cellular response to X-ray  (ISO)
DNA damage response  (IDA,ISO)
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator  (ISO,ISS)
DNA repair-dependent chromatin remodeling  (IEA,ISO)
double-strand break repair  (ISO)
double-strand break repair via homologous recombination  (IBA,IMP,ISO)
establishment of mitotic spindle orientation  (ISO,ISS)
innate immune response  (IEA)
lipid droplet disassembly  (ISO,ISS)
negative regulation of DNA-templated transcription  (ISO)
negative regulation of double-strand break repair via homologous recombination  (IEA,ISO)
negative regulation of interleukin-2 production  (IEA,ISO)
negative regulation of transcription by RNA polymerase II  (IEA,ISO)
neural tube development  (IDA)
neurogenesis  (IDA)
nucleotide-excision repair  (ISO,ISS)
peptidyl-lysine acetylation  (IDA,ISO)
positive regulation of aggrephagy  (IEA,ISO)
positive regulation of attachment of mitotic spindle microtubules to kinetochore  (ISO,ISS)
positive regulation of autophagy  (IDA,ISO)
positive regulation of circadian rhythm  (IDA)
positive regulation of DNA-templated transcription  (ISO,ISS,NAS)
positive regulation of double-strand break repair via homologous recombination  (ISO,ISS)
positive regulation of innate immune response  (ISO)
positive regulation of mitotic sister chromatid segregation  (ISO,ISS)
positive regulation of myoblast differentiation  (ISO,ISS)
positive regulation of protein acetylation  (IEA,ISO)
positive regulation of regulatory T cell differentiation  (IMP,ISO)
positive regulation of transcription by RNA polymerase II  (IGI,ISO,ISS)
positive regulation of triglyceride biosynthetic process  (ISO,ISS)
proteasome-mediated ubiquitin-dependent protein catabolic process  (IEA,ISO)
protein acetylation  (IMP)
protein modification process  (ISO)
regulation of apoptotic process  (NAS)
regulation of cell cycle  (ISO)
regulation of chromatin organization  (NAS)
regulation of double-strand break repair  (NAS)
regulation of hematopoietic stem cell differentiation  (IMP)
regulation of transcription by RNA polymerase II  (IDA)
response to ionizing radiation  (IEA,ISO)
sperm DNA condensation  (IMP)
spermatid development  (IMP)

Cellular Component

Molecular Function
chromatin binding  (IDA,ISO)
DNA-binding transcription factor binding  (IEA,ISO)
histone acetyltransferase activity  (IMP,ISO)
histone crotonyltransferase activity  (IEA)
histone H2A acetyltransferase activity  (ISO,ISS)
histone H2AK5 acetyltransferase activity  (IEA,ISO)
histone H2AK9 acetyltransferase activity  (IEA)
histone H2BK12 acetyltransferase activity  (IEA)
histone H2BK5 acetyltransferase activity  (IEA)
histone H3K122 acetyltransferase activity  (IEA)
histone H3K14 acetyltransferase activity  (IEA)
histone H3K18 acetyltransferase activity  (IEA)
histone H3K23 acetyltransferase activity  (IEA)
histone H3K27 acetyltransferase activity  (IEA)
histone H3K36 acetyltransferase activity  (IEA)
histone H3K4 acetyltransferase activity  (IEA)
histone H3K56 acetyltransferase activity  (IEA)
histone H3K9 acetyltransferase activity  (IEA)
histone H4 acetyltransferase activity  (ISO)
histone H4K12 acetyltransferase activity  (IEA)
histone H4K16 acetyltransferase activity  (IBA,IEA,ISO)
histone H4K5 acetyltransferase activity  (IEA)
histone H4K8 acetyltransferase activity  (IEA)
histone lactyltransferase (CoA-dependent) activity  (IEA)
metal ion binding  (IEA)
peptide 2-hydroxyisobutyryltransferase activity  (IEA)
peptide butyryltransferase activity  (ISO,ISS)
peptide crotonyltransferase activity  (ISO,ISS)
peptide lactyltransferase (CoA-dependent) activity  (ISS)
peptide-lysine-N-acetyltransferase activity  (IDA,ISO)
phospholipase binding  (ISO)
protein binding  (IPI)
protein-containing complex binding  (ISO)
transcription coactivator activity  (IDA,ISO,ISS)

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transcriptional regulation by p53. Beckerman R and Prives C, Cold Spring Harb Perspect Biol. 2010 Aug;2(8):a000935. doi: 10.1101/cshperspect.a000935. Epub 2010 Apr 28.
2. ATM protein kinase: the linchpin of cellular defenses to stress. Bhatti S, etal., Cell Mol Life Sci. 2011 Sep;68(18):2977-3006. doi: 10.1007/s00018-011-0683-9. Epub 2011 May 2.
3. Iron deficiency alters expression of genes implicated in Alzheimer disease pathogenesis. Carlson ES, etal., Brain Res. 2008 Aug 7.
4. Characterisation of a Tip60 specific inhibitor, NU9056, in prostate cancer. Coffey K, etal., PLoS One. 2012;7(10):e45539. doi: 10.1371/journal.pone.0045539. Epub 2012 Oct 8.
5. Tip60 is a haplo-insufficient tumour suppressor required for an oncogene-induced DNA damage response. Gorrini C, etal., Nature. 2007 Aug 30;448(7157):1063-7.
6. Modes of p53 regulation. Kruse JP and Gu W, Cell. 2009 May 15;137(4):609-22. doi: 10.1016/j.cell.2009.04.050.
7. MGDs mouse GO annotations MGD data from the GO Consortium
8. Histone-modifier gene expression profiles are associated with pathological and clinical outcomes in human breast cancer. Patani N, etal., Anticancer Res. 2011 Dec;31(12):4115-25.
9. Physical and functional HAT/HDAC interplay regulates protein acetylation balance. Peserico A and Simone C, J Biomed Biotechnol. 2011;2011:371832. doi: 10.1155/2011/371832. Epub 2010 Dec 5.
10. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
11. Mouse MP Annotation Import Pipeline RGD automated import pipeline
12. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. The ATM signaling network in development and disease. Stracker TH, etal., Front Genet. 2013 Mar 25;4:37. doi: 10.3389/fgene.2013.00037. eCollection 2013.
15. The INO80 family of chromatin-remodeling enzymes: regulators of histone variant dynamics. Watanabe S and Peterson CL, Cold Spring Harb Symp Quant Biol. 2010;75:35-42. doi: 10.1101/sqb.2010.75.063. Epub 2011 Apr 18.
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11111051   PMID:11217851   PMID:12036595   PMID:12464179   PMID:12466851   PMID:12477932   PMID:12801643   PMID:14610273  
PMID:14681479   PMID:14687547   PMID:14966270   PMID:15065000   PMID:15782199   PMID:15944124   PMID:15985650   PMID:16141072   PMID:16141073   PMID:16597624   PMID:16678094   PMID:17015433  
PMID:17110330   PMID:17255939   PMID:17368826   PMID:17517537   PMID:17636029   PMID:17980166   PMID:18022353   PMID:18096664   PMID:18390577   PMID:18414493   PMID:18614019   PMID:19176879  
PMID:19282473   PMID:19362146   PMID:19842187   PMID:19909775   PMID:20059953   PMID:20159953   PMID:20211142   PMID:21267068   PMID:21427130   PMID:21540835   PMID:21658600   PMID:21677750  
PMID:21858214   PMID:21873635   PMID:21936881   PMID:22348108   PMID:22354990   PMID:22539723   PMID:22579476   PMID:22586264   PMID:22766506   PMID:23754744   PMID:23810942   PMID:23995786  
PMID:24141283   PMID:24194600   PMID:24287617   PMID:24302573   PMID:24621507   PMID:24835996   PMID:24853677   PMID:24870614   PMID:26291311   PMID:26700317   PMID:26915295   PMID:27153538  
PMID:27768769   PMID:27769803   PMID:28445719   PMID:28694333   PMID:29184203   PMID:29765047   PMID:30297459   PMID:30297694   PMID:30559296   PMID:30655546   PMID:30699357   PMID:30704899  
PMID:31294688   PMID:31700011   PMID:32542325   PMID:32817552   PMID:33609538   PMID:34610340   PMID:34650217   PMID:34651296   PMID:35986817   PMID:36377816   PMID:36417913   PMID:36768434  
PMID:36916958   PMID:37024457   PMID:38355793   PMID:38402617   PMID:39422647  


Genomics

Comparative Map Data
Kat5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39195,653,042 - 5,661,584 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl195,653,042 - 5,660,265 (-)EnsemblGRCm39 Ensembl
GRCm38195,603,014 - 5,611,556 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl195,603,014 - 5,610,237 (-)EnsemblGRCm38mm10GRCm38
MGSCv37195,603,418 - 5,610,029 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36195,603,418 - 5,610,029 (-)NCBIMGSCv36mm8
Celera195,473,388 - 5,479,999 (-)NCBICelera
Cytogenetic Map19ANCBI
cM Map194.34NCBI
KAT5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381165,712,018 - 65,719,604 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1165,711,996 - 65,719,604 (+)EnsemblGRCh38hg38GRCh38
GRCh371165,479,723 - 65,487,075 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361165,236,065 - 65,243,651 (+)NCBINCBI36Build 36hg18NCBI36
Build 341165,236,064 - 65,243,650NCBI
Celera1162,806,503 - 62,814,088 (+)NCBICelera
Cytogenetic Map11q13.1NCBI
HuRef1161,806,327 - 61,813,930 (+)NCBIHuRef
CHM1_11165,363,389 - 65,370,993 (+)NCBICHM1_1
T2T-CHM13v2.01165,706,411 - 65,713,762 (+)NCBIT2T-CHM13v2.0
Kat5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81212,325,089 - 212,332,640 (-)NCBIGRCr8
mRatBN7.21202,895,751 - 202,903,178 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1202,895,751 - 202,903,458 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1211,248,063 - 211,255,604 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01218,341,145 - 218,348,449 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01211,032,196 - 211,039,500 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01220,967,795 - 220,974,596 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1220,967,796 - 220,974,597 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01227,898,843 - 227,906,221 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41208,233,434 - 208,240,738 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11208,387,311 - 208,393,493 (-)NCBI
Celera1200,431,510 - 200,438,814 (-)NCBICelera
Cytogenetic Map1q43NCBI
Kat5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542219,557,498 - 19,565,036 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542219,557,498 - 19,565,044 (-)NCBIChiLan1.0ChiLan1.0
KAT5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2966,917,509 - 66,949,266 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11167,960,283 - 67,992,053 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01161,071,118 - 61,078,667 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11164,405,088 - 64,412,667 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1164,404,572 - 64,412,667 (+)Ensemblpanpan1.1panPan2
KAT5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11851,499,615 - 51,507,434 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1851,499,938 - 51,576,699 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1850,108,124 - 50,115,932 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01852,537,753 - 52,545,551 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1852,537,754 - 52,545,323 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11851,637,256 - 51,645,064 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01851,211,884 - 51,219,692 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01852,001,339 - 52,009,137 (-)NCBIUU_Cfam_GSD_1.0
Kat5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049477,325,177 - 7,332,932 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365993,766,242 - 3,776,128 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365993,767,526 - 3,775,416 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KAT5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl26,560,513 - 6,572,466 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.126,560,544 - 6,572,461 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.225,668,370 - 5,676,947 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KAT5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.118,528,097 - 8,544,512 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl18,526,788 - 8,544,972 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038105,821,178 - 105,829,346 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kat5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476720,666,763 - 20,675,164 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476720,668,759 - 20,675,367 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Kat5
220 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:226
Count of miRNA genes:180
Interacting mature miRNAs:204
Transcripts:ENSMUST00000113641
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142302Nstr1_mnerve sheath tumor resistance QTL 1 (mouse)Not determined19122371338Mouse
1301271Datd_mdopamine transporter density (mouse)Not determined19132340234Mouse
1300923Bits4_mbitterness sensitivity 4 (mouse)Not determined19332321637323348Mouse
11039522Tbbr4_mTrypanosoma brucei brucei response 4 (mouse)19531332639313470Mouse
25394536Skmw86_mskeletal muscle weight 86, TA (mouse)1950648178957825Mouse
4142161Drinksac2_mdrink saccharin 2 (mouse)Not determined120695286Mouse
1357819Tgct2_mtesticular germ cell tumor 2 (mouse)Not determined19332855120539663Mouse
4142406Pbctlp1_mperipheral blood cytotoxic T lymphocyte percentage 1 (mouse)Not determined132875174Mouse
1300776Lfp3_mlong free running period 3 (mouse)Not determined19120328703Mouse
1300904Chab5_mcholesterol absorption 5 (mouse)Not determined19165376435653927Mouse
26884385Skwq14_mskull length QTL 14, 16 week (mouse)19325000035877400Mouse
1301800Faq10_mfluctuating asymmetry QTL 10 (mouse)Not determined19332321637323348Mouse
1300591Pas3_mpulmonary adenoma susceptibility 3 (mouse)Not determined19332321637323348Mouse
1302126Skull26_mskull morphology 26 (mouse)Not determined19332321637323348Mouse

Markers in Region
AI839539  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38195,603,031 - 5,603,136UniSTSGRCm38
MGSCv37195,603,031 - 5,603,136UniSTSGRCm37
Celera195,473,001 - 5,473,106UniSTS
Cytogenetic Map19AUniSTS
Whitehead/MRC_RH1954.9UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001199247 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001199248 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001199249 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001362370 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001362371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001362372 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_178637 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_155544 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006531860 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB055409 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC126029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF528194 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF528195 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF528196 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK133843 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK143674 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK146352 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159568 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK160077 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK177994 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK187951 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK195015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205910 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK206382 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK219598 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK219943 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY061983 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC022768 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC110675 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC129967 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC129968 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY269987 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CA317697 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ080877 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ139980 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DV648619 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000113641   ⟹   ENSMUSP00000109271
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl195,653,042 - 5,660,265 (-)Ensembl
GRCm38.p6 Ensembl195,603,014 - 5,610,237 (-)Ensembl
Ensembl Acc Id: ENSMUST00000235701   ⟹   ENSMUSP00000158181
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl195,653,045 - 5,660,076 (-)Ensembl
GRCm38.p6 Ensembl195,603,017 - 5,610,048 (-)Ensembl
Ensembl Acc Id: ENSMUST00000235788
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl195,655,094 - 5,660,072 (-)Ensembl
GRCm38.p6 Ensembl195,605,066 - 5,610,044 (-)Ensembl
Ensembl Acc Id: ENSMUST00000235796   ⟹   ENSMUSP00000157995
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl195,655,587 - 5,658,298 (-)Ensembl
GRCm38.p6 Ensembl195,605,559 - 5,608,270 (-)Ensembl
Ensembl Acc Id: ENSMUST00000236062
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl195,657,810 - 5,659,735 (-)Ensembl
GRCm38.p6 Ensembl195,607,782 - 5,609,707 (-)Ensembl
Ensembl Acc Id: ENSMUST00000236229   ⟹   ENSMUSP00000158391
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl195,653,446 - 5,660,057 (-)Ensembl
GRCm38.p6 Ensembl195,603,418 - 5,610,029 (-)Ensembl
Ensembl Acc Id: ENSMUST00000236259
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl195,658,855 - 5,659,946 (-)Ensembl
GRCm38.p6 Ensembl195,608,827 - 5,609,918 (-)Ensembl
Ensembl Acc Id: ENSMUST00000236264   ⟹   ENSMUSP00000157904
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl195,658,954 - 5,660,079 (-)Ensembl
GRCm38.p6 Ensembl195,608,926 - 5,610,051 (-)Ensembl
Ensembl Acc Id: ENSMUST00000236729
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl195,657,761 - 5,659,817 (-)Ensembl
GRCm38.p6 Ensembl195,607,733 - 5,609,789 (-)Ensembl
Ensembl Acc Id: ENSMUST00000236883   ⟹   ENSMUSP00000157766
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl195,653,042 - 5,660,063 (-)Ensembl
GRCm38.p6 Ensembl195,603,014 - 5,610,035 (-)Ensembl
Ensembl Acc Id: ENSMUST00000236964
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl195,653,044 - 5,659,810 (-)Ensembl
GRCm38.p6 Ensembl195,603,016 - 5,609,782 (-)Ensembl
Ensembl Acc Id: ENSMUST00000237072   ⟹   ENSMUSP00000157522
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl195,653,042 - 5,653,994 (-)Ensembl
GRCm38.p6 Ensembl195,603,014 - 5,603,966 (-)Ensembl
RefSeq Acc Id: NM_001199247   ⟹   NP_001186176
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39195,653,042 - 5,660,122 (-)NCBI
GRCm38195,603,014 - 5,610,094 (-)NCBI
Celera195,472,984 - 5,480,064 (-)ENTREZGENE
cM Map19 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001199248   ⟹   NP_001186177
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39195,653,042 - 5,660,122 (-)NCBI
GRCm38195,603,014 - 5,610,094 (-)NCBI
Celera195,472,984 - 5,480,064 (-)ENTREZGENE
cM Map19 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001199249   ⟹   NP_001186178
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39195,655,150 - 5,660,122 (-)NCBI
GRCm38195,605,122 - 5,610,094 (-)NCBI
Celera195,472,984 - 5,480,064 (-)ENTREZGENE
cM Map19 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001362370   ⟹   NP_001349299
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39195,653,042 - 5,659,772 (-)NCBI
GRCm38195,603,014 - 5,609,744 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001362371   ⟹   NP_001349300
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39195,653,042 - 5,659,772 (-)NCBI
GRCm38195,603,014 - 5,609,744 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001362372   ⟹   NP_001349301
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39195,653,042 - 5,660,122 (-)NCBI
GRCm38195,603,014 - 5,610,094 (-)NCBI
Sequence:
RefSeq Acc Id: NM_178637   ⟹   NP_848752
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39195,653,042 - 5,660,122 (-)NCBI
GRCm38195,603,014 - 5,610,094 (-)NCBI
MGSCv37195,603,418 - 5,610,029 (-)RGD
Celera195,472,984 - 5,480,064 (-)ENTREZGENE
cM Map19 ENTREZGENE
Sequence:
RefSeq Acc Id: NR_155544
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39195,653,042 - 5,660,122 (-)NCBI
GRCm38195,603,014 - 5,610,094 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006531860   ⟹   XP_006531923
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39195,653,042 - 5,661,584 (-)NCBI
GRCm38195,603,014 - 5,611,556 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001186176 (Get FASTA)   NCBI Sequence Viewer  
  NP_001186177 (Get FASTA)   NCBI Sequence Viewer  
  NP_001186178 (Get FASTA)   NCBI Sequence Viewer  
  NP_001349299 (Get FASTA)   NCBI Sequence Viewer  
  NP_001349300 (Get FASTA)   NCBI Sequence Viewer  
  NP_001349301 (Get FASTA)   NCBI Sequence Viewer  
  NP_848752 (Get FASTA)   NCBI Sequence Viewer  
  XP_006531923 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI10676 (Get FASTA)   NCBI Sequence Viewer  
  AAI29968 (Get FASTA)   NCBI Sequence Viewer  
  AAI29969 (Get FASTA)   NCBI Sequence Viewer  
  AAL34981 (Get FASTA)   NCBI Sequence Viewer  
  AAN77140 (Get FASTA)   NCBI Sequence Viewer  
  AAN77141 (Get FASTA)   NCBI Sequence Viewer  
  AAN77142 (Get FASTA)   NCBI Sequence Viewer  
  AAZ67923 (Get FASTA)   NCBI Sequence Viewer  
  BAC53807 (Get FASTA)   NCBI Sequence Viewer  
  BAE27104 (Get FASTA)   NCBI Sequence Viewer  
  EDL33153 (Get FASTA)   NCBI Sequence Viewer  
  EDL33154 (Get FASTA)   NCBI Sequence Viewer  
  EDL33155 (Get FASTA)   NCBI Sequence Viewer  
  EDL33156 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000109271
  ENSMUSP00000109271.3
  ENSMUSP00000157522.2
  ENSMUSP00000157766.2
  ENSMUSP00000157904.2
  ENSMUSP00000157995.2
  ENSMUSP00000158181
  ENSMUSP00000158181.2
  ENSMUSP00000158391
  ENSMUSP00000158391.2
GenBank Protein Q8CHK4 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_848752   ⟸   NM_178637
- Peptide Label: isoform 1
- UniProtKB: Q8CGZ4 (UniProtKB/Swiss-Prot),   Q8CGZ3 (UniProtKB/Swiss-Prot),   Q3YFI9 (UniProtKB/Swiss-Prot),   A1L394 (UniProtKB/Swiss-Prot),   A0A494B9U8 (UniProtKB/Swiss-Prot),   Q8VIH0 (UniProtKB/Swiss-Prot),   Q8CHK4 (UniProtKB/Swiss-Prot),   Q3UJQ1 (UniProtKB/TrEMBL),   A2VDH4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001186176   ⟸   NM_001199247
- Peptide Label: isoform 2
- UniProtKB: A2VDH4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001186177   ⟸   NM_001199248
- Peptide Label: isoform 3
- UniProtKB: A0A494BAP7 (UniProtKB/TrEMBL),   A2VDH4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001186178   ⟸   NM_001199249
- Peptide Label: isoform 4
- Sequence:
RefSeq Acc Id: XP_006531923   ⟸   XM_006531860
- Peptide Label: isoform X1
- UniProtKB: A2VDH4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001349301   ⟸   NM_001362372
- Peptide Label: isoform 6
- UniProtKB: A2VDH4 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001349299   ⟸   NM_001362370
- Peptide Label: isoform 5
RefSeq Acc Id: NP_001349300   ⟸   NM_001362371
- Peptide Label: isoform 5
Ensembl Acc Id: ENSMUSP00000157522   ⟸   ENSMUST00000237072
Ensembl Acc Id: ENSMUSP00000157766   ⟸   ENSMUST00000236883
Ensembl Acc Id: ENSMUSP00000157904   ⟸   ENSMUST00000236264
Ensembl Acc Id: ENSMUSP00000158391   ⟸   ENSMUST00000236229
Ensembl Acc Id: ENSMUSP00000109271   ⟸   ENSMUST00000113641
Ensembl Acc Id: ENSMUSP00000158181   ⟸   ENSMUST00000235701
Ensembl Acc Id: ENSMUSP00000157995   ⟸   ENSMUST00000235796
Protein Domains
Chromo   MYST-type HAT   Tudor-knot

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8CHK4-F1-model_v2 AlphaFold Q8CHK4 1-513 view protein structure

Promoters
RGD ID:6847588
Promoter ID:MM_ACW:25857
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   BoneMarrow_0Hour,   Brain,   Liver,   Lung,   Spleen
Transcripts:HTATIP.MSEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36195,603,491 - 5,604,542 (-)MPROMDB
RGD ID:6830206
Promoter ID:MM_KWN:26096
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000025865,   ENSMUST00000099970,   ENSMUST00000113640,   ENSMUST00000113641,   UC008GDY.1,   UC008GEC.1,   UC008GED.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36195,609,516 - 5,610,387 (-)MPROMDB
RGD ID:13678552
Promoter ID:EPDNEW_M23425
Type:single initiation site
Name:Kat5_1
Description:Mus musculus K acetyltransferase 5 , transcript variant 4, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38195,610,045 - 5,610,105EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1932051 AgrOrtholog
Ensembl Genes ENSMUSG00000024926 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000113641 ENTREZGENE
  ENSMUST00000113641.4 UniProtKB/Swiss-Prot
  ENSMUST00000235701 ENTREZGENE
  ENSMUST00000235701.2 UniProtKB/TrEMBL
  ENSMUST00000235788 ENTREZGENE
  ENSMUST00000235796.2 UniProtKB/TrEMBL
  ENSMUST00000236229 ENTREZGENE
  ENSMUST00000236229.2 UniProtKB/Swiss-Prot
  ENSMUST00000236264.2 UniProtKB/TrEMBL
  ENSMUST00000236883 ENTREZGENE
  ENSMUST00000236883.2 UniProtKB/Swiss-Prot
  ENSMUST00000236964 ENTREZGENE
  ENSMUST00000237072.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.30.30.140 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.630.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  N-acetyl transferase-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Acyl_CoA_acyltransferase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Chromo-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Chromo/chromo_shadow_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HAT_MYST-type UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MYST_HAT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tudor-knot UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Zf-MYST UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:81601 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1932051 ENTREZGENE
NCBI Gene 81601 ENTREZGENE
PANTHER HISTONE ACETYLTRANSFERASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HISTONE ACETYLTRANSFERASE KAT5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam MOZ_SAS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tudor-knot UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-MYST UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Kat5 PhenoGen
PROSITE MYST_HAT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART CHROMO UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54160 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF55729 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A494B979_MOUSE UniProtKB/TrEMBL
  A0A494B9U8 ENTREZGENE
  A0A494BA68_MOUSE UniProtKB/TrEMBL
  A0A494BA96_MOUSE UniProtKB/TrEMBL
  A0A494BAP7 ENTREZGENE, UniProtKB/TrEMBL
  A1L394 ENTREZGENE
  A2VDH4 ENTREZGENE, UniProtKB/TrEMBL
  KAT5_MOUSE UniProtKB/Swiss-Prot
  Q3UJQ1 ENTREZGENE, UniProtKB/TrEMBL
  Q3YFI9 ENTREZGENE
  Q8CGZ3 ENTREZGENE
  Q8CGZ4 ENTREZGENE
  Q8CHK4 ENTREZGENE
  Q8VIH0 ENTREZGENE
UniProt Secondary A0A494B9U8 UniProtKB/Swiss-Prot
  A1L394 UniProtKB/Swiss-Prot
  Q3YFI9 UniProtKB/Swiss-Prot
  Q8CGZ3 UniProtKB/Swiss-Prot
  Q8CGZ4 UniProtKB/Swiss-Prot
  Q8VIH0 UniProtKB/Swiss-Prot