Sfrp1 (secreted frizzled-related protein 1) - Rat Genome Database

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Gene: Sfrp1 (secreted frizzled-related protein 1) Mus musculus
Symbol: Sfrp1
Name: secreted frizzled-related protein 1
RGD ID: 735755
Description: Predicted to enable several functions, including Wnt-protein binding activity; frizzled binding activity; and heparin binding activity. Involved in several processes, including cellular response to X-ray; cellular response to estrogen stimulus; and negative regulation of B cell differentiation. Acts upstream of or within several processes, including animal organ development; chordate embryonic development; and regulation of signal transduction. Located in extracellular space. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; heart; and sensory organ. Orthologous to human SFRP1 (secreted frizzled related protein 1); PARTICIPATES IN Wnt signaling, canonical pathway; Wnt signaling pathway; INTERACTS WITH (-)-epigallocatechin 3-gallate; 1,1-dichloroethene; 1,2-dimethylhydrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2210415K03Rik; AW011917; AW107218; AW742929; secreted frizzled-related sequence protein 1; sFR; sFRP-1
RGD Orthologs
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm39823,901,401 - 23,939,648 (+)NCBIGRCm39mm39
GRCm39 Ensembl823,901,518 - 23,939,648 (+)Ensembl
GRCm38823,411,383 - 23,449,632 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl823,411,502 - 23,449,632 (+)EnsemblGRCm38mm10GRCm38
MGSCv37824,521,974 - 24,560,104 (+)NCBIGRCm37mm9NCBIm37
MGSCv36824,877,063 - 24,915,177 (+)NCBImm8
Celera824,905,624 - 24,944,019 (+)NCBICelera
Cytogenetic Map8A2NCBI
cM Map811.48NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (EXP)
1,1-dichloroethene  (EXP)
1,2-dimethylhydrazine  (EXP)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2-hydroxypropanoic acid  (ISO)
3-aminobenzamide  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (EXP)
3-methylcholanthrene  (EXP)
4-hydroxyphenyl retinamide  (EXP)
5-aza-2'-deoxycytidine  (ISO)
5-formyltetrahydrofolic acid  (ISO)
6-propyl-2-thiouracil  (ISO)
8-Br-cAMP  (ISO)
acetamide  (ISO)
aflatoxin B1  (ISO)
aflatoxin B2  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (ISO)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (EXP,ISO)
beta-naphthoflavone  (ISO)
biguanides  (ISO)
bisphenol A  (ISO)
bleomycin A2  (EXP)
boron nitride  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
calciol  (EXP)
carbamazepine  (ISO)
carbon nanotube  (EXP,ISO)
chloropicrin  (ISO)
choline  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
Cuprizon  (ISO)
cytarabine  (ISO)
decabromodiphenyl ether  (ISO)
dexamethasone  (EXP,ISO)
diarsenic trioxide  (ISO)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
ethanol  (EXP,ISO)
folic acid  (EXP,ISO)
glyphosate  (ISO)
heparin  (ISO)
hydroquinone  (ISO)
lead diacetate  (ISO)
mercury atom  (ISO)
mercury dibromide  (ISO)
mercury(0)  (ISO)
methotrexate  (ISO)
methylmercury chloride  (ISO)
mifepristone  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
naphthalene  (EXP)
nickel atom  (ISO)
oxaliplatin  (ISO)
p-chloromercuribenzoic acid  (ISO)
p-menthan-3-ol  (ISO)
panobinostat  (ISO)
PCB138  (EXP)
phenylmercury acetate  (ISO)
phorbol 13-acetate 12-myristate  (EXP)
pirinixic acid  (EXP)
pravastatin  (EXP)
quercetin  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
serpentine asbestos  (ISO)
silicon dioxide  (ISO)
silver atom  (EXP)
silver(0)  (EXP)
sodium arsenate  (EXP,ISO)
Soman  (ISO)
Sporidesmin  (ISO)
sulforaphane  (EXP)
sunitinib  (ISO)
tamoxifen  (EXP)
temozolomide  (ISO)
tetrachloromethane  (ISO)
theaflavin  (EXP)
thimerosal  (ISO)
titanium dioxide  (EXP)
topotecan  (ISO)
trichostatin A  (ISO)
valproic acid  (ISO)
vancomycin  (EXP)
vorinostat  (ISO)
XL147  (EXP)
zaragozic acid A  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
actin cytoskeleton organization  (ISO)
anterior/posterior pattern specification  (IGI)
bone trabecula formation  (IMP)
canonical Wnt signaling pathway  (IBA,ISO)
cell differentiation  (IEA)
cellular response to BMP stimulus  (ISO)
cellular response to estradiol stimulus  (ISO)
cellular response to estrogen stimulus  (IDA,ISO)
cellular response to fibroblast growth factor stimulus  (ISO)
cellular response to growth factor stimulus  (ISO)
cellular response to heparin  (ISO)
cellular response to hypoxia  (ISO)
cellular response to interleukin-1  (ISO)
cellular response to prostaglandin E stimulus  (ISO)
cellular response to starvation  (ISO)
cellular response to transforming growth factor beta stimulus  (ISO)
cellular response to tumor necrosis factor  (ISO)
cellular response to vitamin D  (ISO)
cellular response to X-ray  (IDA)
convergent extension involved in somitogenesis  (IGI)
development of primary male sexual characteristics  (IGI)
digestive tract morphogenesis  (IGI)
dopaminergic neuron differentiation  (IDA)
dorsal/ventral axis specification  (ISO)
female gonad development  (IGI)
hematopoietic progenitor cell differentiation  (ISO)
hematopoietic stem cell differentiation  (ISO)
hemopoiesis  (IMP)
male gonad development  (IGI)
negative regulation of androgen receptor signaling pathway  (ISO)
negative regulation of apoptotic process  (ISO)
negative regulation of B cell differentiation  (IMP,ISO)
negative regulation of BMP signaling pathway  (IGI)
negative regulation of bone remodeling  (ISO)
negative regulation of canonical Wnt signaling pathway  (IBA,IDA,IGI,ISO)
negative regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation  (ISO)
negative regulation of cell growth  (ISO)
negative regulation of cell migration  (ISO)
negative regulation of cell population proliferation  (ISO)
negative regulation of epithelial cell proliferation  (ISO)
negative regulation of epithelial to mesenchymal transition  (ISO)
negative regulation of fibroblast apoptotic process  (ISO)
negative regulation of fibroblast proliferation  (ISO)
negative regulation of gene expression  (IMP,ISO)
negative regulation of insulin secretion  (ISO)
negative regulation of JUN kinase activity  (IGI)
negative regulation of ossification  (IMP,ISO)
negative regulation of osteoblast differentiation  (IMP)
negative regulation of osteoblast proliferation  (IMP,ISO)
negative regulation of osteoclast differentiation  (IMP,ISO)
negative regulation of peptidyl-tyrosine phosphorylation  (ISO)
negative regulation of planar cell polarity pathway involved in axis elongation  (IGI)
negative regulation of transcription, DNA-templated  (ISO)
negative regulation of Wnt signaling pathway  (IGI,ISO)
negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification  (ISO)
neural crest cell fate commitment  (IMP)
neural tube closure  (IGI)
neural tube development  (IGI)
non-canonical Wnt signaling pathway  (IBA)
osteoblast differentiation  (ISO)
planar cell polarity pathway involved in neural tube closure  (IGI)
positive regulation of apoptotic process  (ISO)
positive regulation of canonical Wnt signaling pathway  (ISO)
positive regulation of cell growth  (ISO)
positive regulation of cell population proliferation  (ISO)
positive regulation of epithelial cell proliferation  (ISO)
positive regulation of extrinsic apoptotic signaling pathway  (IMP)
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors  (ISO)
positive regulation of fat cell differentiation  (ISO)
positive regulation of fibroblast apoptotic process  (ISO)
positive regulation of non-canonical Wnt signaling pathway  (ISO)
positive regulation of smoothened signaling pathway  (ISO)
positive regulation of transcription, DNA-templated  (ISO)
positive regulation of Wnt signaling pathway  (ISO)
prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis  (IMP)
regulation of branching involved in prostate gland morphogenesis  (IMP)
regulation of cell cycle process  (ISO)
regulation of establishment of planar polarity  (IGI)
regulation of midbrain dopaminergic neuron differentiation  (IGI)
regulation of neuron projection development  (IDA)
regulation of ossification  (ISO)
response to organic cyclic compound  (ISO)
response to xenobiotic stimulus  (IDA)
somatic stem cell population maintenance  (IMP)
somitogenesis  (IEP,IGI)
stromal-epithelial cell signaling involved in prostate gland development  (IEP)
substrate adhesion-dependent cell spreading  (ISO)
ureteric bud development  (IEP)
Wnt signaling pathway  (IEA)
Wnt signaling pathway involved in somitogenesis  (IGI)
Wnt signaling pathway, planar cell polarity pathway  (IDA)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View

Additional References at PubMed
PMID:9096311   PMID:9192640   PMID:9671940   PMID:9739103   PMID:9853965   PMID:10349636   PMID:10640709   PMID:10654605   PMID:11042159   PMID:11076861   PMID:11335128   PMID:11731256  
PMID:11731265   PMID:12055200   PMID:12210517   PMID:12412008   PMID:12477932   PMID:12490556   PMID:12812787   PMID:12815618   PMID:14581414   PMID:14681479   PMID:14976225   PMID:15306229  
PMID:15457338   PMID:15476588   PMID:15489334   PMID:15634693   PMID:15782199   PMID:15809042   PMID:15880404   PMID:16141072   PMID:16141073   PMID:16149051   PMID:16288033   PMID:16467359  
PMID:16545622   PMID:16567562   PMID:16575902   PMID:16602821   PMID:16672052   PMID:16849540   PMID:16920270   PMID:16942767   PMID:17044082   PMID:17158062   PMID:17287250   PMID:17389379  
PMID:17462603   PMID:17481602   PMID:17485441   PMID:17644613   PMID:17720858   PMID:18156211   PMID:18255031   PMID:18257070   PMID:18287559   PMID:18322704   PMID:18371946   PMID:18392598  
PMID:18403408   PMID:18498122   PMID:18521945   PMID:18554416   PMID:18565209   PMID:18729207   PMID:18941195   PMID:19100252   PMID:19185060   PMID:19188438   PMID:19223557   PMID:19254787  
PMID:19282366   PMID:19285468   PMID:19300477   PMID:19301255   PMID:19369394   PMID:19473496   PMID:19515997   PMID:19562671   PMID:19664990   PMID:19778523   PMID:19799774   PMID:19850029  
PMID:19896444   PMID:19924825   PMID:20027618   PMID:20130188   PMID:20185815   PMID:20308569   PMID:20595636   PMID:20887955   PMID:20890044   PMID:21041481   PMID:21150899   PMID:21267068  
PMID:21478884   PMID:21490069   PMID:21586556   PMID:21731673   PMID:21779340   PMID:21799872   PMID:21806977   PMID:21836067   PMID:21858105   PMID:21873635   PMID:21896628   PMID:22166339  
PMID:22173065   PMID:22235033   PMID:22290867   PMID:22359602   PMID:22371338   PMID:22535492   PMID:22863011   PMID:22928951   PMID:23022129   PMID:23044044   PMID:23087175   PMID:23213461  
PMID:23261541   PMID:23349620   PMID:23469192   PMID:23827310   PMID:24006456   PMID:24038862   PMID:24055172   PMID:24080158   PMID:24140542   PMID:24278461   PMID:24339864   PMID:24523460  
PMID:24590292   PMID:24885183   PMID:24952961   PMID:25212222   PMID:25253698   PMID:25669938   PMID:25788689   PMID:25809273   PMID:25827793   PMID:25920569   PMID:26235626   PMID:26288816  
PMID:26371318   PMID:26450967   PMID:26859490   PMID:27395006   PMID:27445154   PMID:27671872   PMID:27713059   PMID:28009287   PMID:28250050   PMID:28292423   PMID:28400434   PMID:28535371  
PMID:28605600   PMID:28687085   PMID:28894084   PMID:29196093   PMID:29215727   PMID:29463648   PMID:29513653   PMID:30084950   PMID:30586565   PMID:30635555   PMID:31257105   PMID:31308530  
PMID:32198470   PMID:32325033   PMID:32553120   PMID:32571845   PMID:32715478   PMID:33109217  


Comparative Map Data
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm39823,901,401 - 23,939,648 (+)NCBIGRCm39mm39
GRCm39 Ensembl823,901,518 - 23,939,648 (+)Ensembl
GRCm38823,411,383 - 23,449,632 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl823,411,502 - 23,449,632 (+)EnsemblGRCm38mm10GRCm38
MGSCv37824,521,974 - 24,560,104 (+)NCBIGRCm37mm9NCBIm37
MGSCv36824,877,063 - 24,915,177 (+)NCBImm8
Celera824,905,624 - 24,944,019 (+)NCBICelera
Cytogenetic Map8A2NCBI
cM Map811.48NCBI
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl841,261,962 - 41,309,473 (-)EnsemblGRCh38hg38GRCh38
GRCh38841,261,962 - 41,309,473 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37841,119,481 - 41,166,992 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36841,238,635 - 41,286,137 (-)NCBINCBI36hg18NCBI36
Build 34841,238,635 - 41,286,137NCBI
Celera840,068,517 - 40,116,053 (-)NCBI
Cytogenetic Map8p11.21NCBI
HuRef839,647,919 - 39,695,566 (-)NCBIHuRef
CHM1_1841,167,412 - 41,215,102 (-)NCBICHM1_1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
mRatBN7.21668,575,763 - 68,613,905 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1668,575,763 - 68,614,286 (-)Ensembl
Rnor_6.01673,372,007 - 73,410,777 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1673,372,007 - 73,410,777 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01673,006,739 - 73,045,509 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41673,030,458 - 73,067,304 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11673,031,966 - 73,066,892 (-)NCBI
Celera1666,467,691 - 66,505,810 (-)NCBICelera
Cytogenetic Map16q12.5NCBI
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
ChiLan1.0 EnsemblNW_0049555361,663,344 - 1,703,514 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555361,663,721 - 1,702,678 (+)NCBIChiLan1.0ChiLan1.0
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
PanPan1.1837,956,423 - 38,001,865 (-)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v0840,507,027 - 40,555,053 (-)NCBIMhudiblu_PPA_v0panPan3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
CanFam3.11624,262,451 - 24,306,162 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1624,261,946 - 24,302,964 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1624,766,734 - 24,810,532 (+)NCBI
ROS_Cfam_1.01626,010,215 - 26,053,984 (+)NCBI
UMICH_Zoey_3.11624,382,043 - 24,425,801 (+)NCBI
UNSW_CanFamBas_1.01624,943,898 - 24,987,804 (+)NCBI
UU_Cfam_GSD_1.01624,995,596 - 25,039,359 (+)NCBI
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
HiC_Itri_2NW_02440494347,320,083 - 47,364,001 (+)NCBI
SpeTri2.0NW_0049367851,276,478 - 1,320,397 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
Sscrofa11.1 Ensembl1710,436,426 - 10,489,748 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11710,436,414 - 10,489,773 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21711,790,230 - 11,878,539 (-)NCBISscrofa10.2Sscrofa10.2susScr3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
ChlSab1.1839,243,775 - 39,289,050 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl839,243,780 - 39,288,984 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660522,558,131 - 2,612,751 (+)NCBIVero_WHO_p1.0
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
HetGla 1.0NW_0046247802,133,105 - 2,172,301 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv37824,556,800 - 24,557,756UniSTSGRCm37
MGSCv37824,556,798 - 24,557,756UniSTSGRCm37
MGSCv37824,559,804 - 24,560,049UniSTSGRCm37
Celera824,940,715 - 24,941,665UniSTS
Celera824,943,714 - 24,943,964UniSTS
Celera824,940,713 - 24,941,665UniSTS
Cytogenetic Map8A2UniSTS
cM Map89.5UniSTS
cM Map89.5UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38823,446,832 - 23,447,088UniSTSGRCm38
MGSCv37824,557,304 - 24,557,560UniSTSGRCm37
Celera824,941,219 - 24,941,469UniSTS
Cytogenetic Map8A2UniSTS
cM Map89.5UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38823,447,800 - 23,447,940UniSTSGRCm38
MGSCv37824,558,272 - 24,558,412UniSTSGRCm37
Celera824,942,181 - 24,942,321UniSTS
Cytogenetic Map8A2UniSTS
cM Map89.5UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38823,449,159 - 23,449,304UniSTSGRCm38
MGSCv37824,559,631 - 24,559,776UniSTSGRCm37
Celera824,943,541 - 24,943,686UniSTS
Cytogenetic Map8A2UniSTS
cM Map89.5UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38823,447,979 - 23,448,150UniSTSGRCm38
MGSCv37824,558,451 - 24,558,622UniSTSGRCm37
Celera824,942,360 - 24,942,531UniSTS
Cytogenetic Map8A2UniSTS
cM Map89.5UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map8A2UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38823,446,326 - 23,447,284UniSTSGRCm38
MGSCv37824,556,798 - 24,557,756UniSTSGRCm37
Celera824,940,713 - 24,941,665UniSTS
Cytogenetic Map8A2UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38823,446,328 - 23,447,284UniSTSGRCm38
MGSCv37824,556,800 - 24,557,756UniSTSGRCm37
Celera824,940,715 - 24,941,665UniSTS
Cytogenetic Map8A2UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map8A2UniSTS
cM Map89.5UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map8A2UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38823,449,332 - 23,449,577UniSTSGRCm38
MGSCv37824,559,804 - 24,560,049UniSTSGRCm37
Celera824,943,714 - 24,943,964UniSTS
Cytogenetic Map8A2UniSTS

QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13432571Scvg1_msubcutaneous vessel growth QTL 1 (mouse)8124701082Mouse
11533914Mts5_mmammary tumor susceptibility 5 (mouse)8130397432Mouse
4140978Nilac5_mnicotine induced locomotor activity 5 (mouse)Not determined8131723288Mouse
27226756Femd2_mfemur midshaft diameter 2, 5 week (mouse)8490000034600000Mouse
1301532Scc8_mcolon tumor susceptibility 8 (mouse)Not determined8716249934642953Mouse
1300906Ap8q_malcohol preference 8 QTL (mouse)Not determined8749417341494326Mouse
1301128Sluc20_msusceptibility to lung cancer 20 (mouse)Not determined8761318541613356Mouse
1301929Eae24_msusceptibility to experimental allergic encephalomyelitis 24 (mouse)Not determined8761318541613356Mouse
10412209Cypr7_mcytokine production 7 (mouse)Not determined8761318541613356Mouse
11532713Sluc42_msusceptibility to lung cancer 42 (mouse)81339721034854071Mouse
1558870Eae36_mexperimental allergic encephalomyelitis susceptibility 36 (mouse)Not determined81472316071045600Mouse
1301088Alcw6_malcohol withdrawal 6 (mouse)Not determined81501654449016701Mouse
1300912Daq19_mdirectional asymmetry QTL 19 (mouse)Not determined81501654449016701Mouse
1301298Pgia4_mproteoglycan induced arthritis 4 (mouse)Not determined81607934550079669Mouse
4142199Poats1_mpost-ovarectomy adrenal tumor susceptibility 1 (mouse)Not determined1703261028359439Mouse
1301550Fembrs2_mfemur breaking strength 2 (mouse)Not determined81785394351854071Mouse
1301160Eae14_msusceptibility to experimental allergic encephalomyelitis 14 (mouse)Not determined81898786452987996Mouse
1300603Cd8ts2_mCD8 T cell subset 2 (mouse)Not determined81898786452987996Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1039
Count of miRNA genes:555
Interacting mature miRNAs:691
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (
For more information about miRGate, see PMID:25858286 or access the full paper here.



Reference Sequences
RefSeq Acc Id: ENSMUST00000033952   ⟹   ENSMUSP00000033952
RefSeq Status:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl823,901,518 - 23,939,648 (+)Ensembl
GRCm38.p6 Ensembl823,411,502 - 23,449,632 (+)Ensembl
RefSeq Acc Id: NM_013834   ⟹   NP_038862
RefSeq Status: VALIDATED
Mouse AssemblyChrPosition (strand)Source
GRCm39823,901,518 - 23,939,648 (+)NCBI
GRCm38823,411,502 - 23,449,632 (+)NCBI
MGSCv37824,521,974 - 24,560,104 (+)RGD
Celera824,905,624 - 24,944,019 (+)RGD
RefSeq Acc Id: XM_011242128   ⟹   XP_011240430
RefSeq Status:
Mouse AssemblyChrPosition (strand)Source
GRCm39823,901,401 - 23,939,648 (+)NCBI
GRCm38823,411,383 - 23,449,632 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_038862   ⟸   NM_013834
- Peptide Label: precursor
- UniProtKB: Q8C4U3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011240430   ⟸   XM_011242128
- Peptide Label: isoform X1
- UniProtKB: Q8C4U3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000033952   ⟸   ENSMUST00000033952
Protein Domains

RGD ID:8666717
Promoter ID:EPDNEW_M11390
Type:multiple initiation site
Description:Mus musculus secreted frizzled-related protein 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database,
Experiment Methods:Single-end sequencing.
Mouse AssemblyChrPosition (strand)Source
GRCm38823,411,500 - 23,411,560EPDNEW
RGD ID:6843700
Promoter ID:MM_KWN:53966
SO ACC ID:SO:0000170
Tissues & Cell Lines:ES_Cell,   Kidney
Mouse AssemblyChrPosition (strand)Source
MGSCv36824,521,701 - 24,522,201 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:892014 AgrOrtholog
Ensembl Genes ENSMUSG00000031548 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000033952 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000033952 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.2000.10 UniProtKB/Swiss-Prot UniProtKB/Swiss-Prot
InterPro Frizzled/SFRP UniProtKB/Swiss-Prot
  Frizzled_dom UniProtKB/Swiss-Prot
  Frizzled_dom_sf UniProtKB/Swiss-Prot
  Netrin_domain UniProtKB/Swiss-Prot
  Netrin_module_non-TIMP UniProtKB/Swiss-Prot
  SFRP1 UniProtKB/Swiss-Prot
  SFRP1_CRD UniProtKB/Swiss-Prot
  TIMP-like_OB-fold UniProtKB/Swiss-Prot
KEGG Report mmu:20377 UniProtKB/Swiss-Prot
PANTHER PTHR11309 UniProtKB/Swiss-Prot
  PTHR11309:SF87 UniProtKB/Swiss-Prot
Pfam NTR UniProtKB/Swiss-Prot
  PF01392 UniProtKB/Swiss-Prot
PhenoGen Sfrp1 PhenoGen
PROSITE NTR UniProtKB/Swiss-Prot
  PS50038 UniProtKB/Swiss-Prot
SMART C345C UniProtKB/Swiss-Prot
  FRI UniProtKB/Swiss-Prot
Superfamily-SCOP SSF50242 UniProtKB/Swiss-Prot
  SSF63501 UniProtKB/Swiss-Prot
UniProt Q8C4U3 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary O08861 UniProtKB/Swiss-Prot
  Q505A2 UniProtKB/Swiss-Prot
  Q8R1J4 UniProtKB/Swiss-Prot