Sfrp1 (secreted frizzled-related protein 1) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Sfrp1 (secreted frizzled-related protein 1) Mus musculus
Analyze
Symbol: Sfrp1
Name: secreted frizzled-related protein 1
RGD ID: 735755
MGI Page MGI
Description: Predicted to enable several functions, including Wnt-protein binding activity; frizzled binding activity; and heparin binding activity. Involved in several processes, including cellular response to X-ray; cellular response to estrogen stimulus; and negative regulation of canonical Wnt signaling pathway. Acts upstream of or within several processes, including chordate embryonic development; regulation of signal transduction; and reproductive structure development. Located in extracellular space. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; heart; and sensory organ. Orthologous to human SFRP1 (secreted frizzled related protein 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2210415K03Rik; AW011917; AW107218; AW742929; secreted frizzled-related sequence protein 1; sFR; sFRP-1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39823,901,401 - 23,939,648 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl823,901,518 - 23,939,648 (+)EnsemblGRCm39 Ensembl
GRCm38823,411,383 - 23,449,632 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl823,411,502 - 23,449,632 (+)EnsemblGRCm38mm10GRCm38
MGSCv37824,521,974 - 24,560,104 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36824,877,063 - 24,915,177 (+)NCBIMGSCv36mm8
Celera824,905,624 - 24,944,019 (+)NCBICelera
Cytogenetic Map8A2NCBI
cM Map811.48NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (EXP)
1,1-dichloroethene  (EXP)
1,2-dimethylhydrazine  (EXP)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP)
2-hydroxypropanoic acid  (ISO)
3-aminobenzamide  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (EXP)
3-methylcholanthrene  (EXP)
3-Nitrobenzanthrone  (ISO)
4,4'-sulfonyldiphenol  (EXP)
4-hydroxyphenyl retinamide  (EXP)
5-aza-2'-deoxycytidine  (ISO)
5-formyltetrahydrofolic acid  (ISO)
6-propyl-2-thiouracil  (ISO)
8-Br-cAMP  (ISO)
acetamide  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (ISO)
ammonium chloride  (ISO)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (EXP,ISO)
beta-naphthoflavone  (ISO)
biguanides  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (ISO)
bleomycin A2  (EXP)
boron nitride  (ISO)
Butylbenzyl phthalate  (EXP)
cadmium dichloride  (ISO)
caffeine  (ISO)
calciol  (EXP)
carbamazepine  (ISO)
carbon nanotube  (EXP,ISO)
CGP 52608  (ISO)
chloropicrin  (ISO)
chlorpyrifos  (EXP)
choline  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper(II) chloride  (ISO)
CU-O LINKAGE  (ISO)
Cuprizon  (ISO)
cytarabine  (ISO)
decabromodiphenyl ether  (ISO)
dexamethasone  (EXP,ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP)
diethyl phthalate  (EXP)
diisobutyl phthalate  (EXP)
diisononyl phthalate  (EXP)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
epoxiconazole  (EXP)
ethanol  (EXP,ISO)
folic acid  (EXP,ISO)
glycidyl methacrylate  (ISO)
glyphosate  (ISO)
heparin  (ISO)
hydroquinone  (ISO)
inulin  (EXP)
lead diacetate  (ISO)
mercury atom  (ISO)
mercury dibromide  (ISO)
mercury(0)  (ISO)
methimazole  (ISO)
methotrexate  (ISO)
methoxychlor  (ISO)
methylmercury chloride  (ISO)
microcystin-LR  (ISO)
mifepristone  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
naphthalene  (EXP)
nickel atom  (ISO)
oxaliplatin  (ISO)
ozone  (EXP,ISO)
p-chloromercuribenzoic acid  (ISO)
p-menthan-3-ol  (ISO)
panobinostat  (ISO)
paracetamol  (ISO)
PCB138  (EXP)
perfluorooctane-1-sulfonic acid  (EXP)
phenylmercury acetate  (ISO)
phorbol 13-acetate 12-myristate  (EXP)
pirinixic acid  (EXP)
pravastatin  (EXP)
pregnenolone 16alpha-carbonitrile  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
serpentine asbestos  (ISO)
silicon dioxide  (ISO)
silver atom  (EXP)
silver(0)  (EXP)
sodium arsenate  (EXP,ISO)
sodium arsenite  (EXP,ISO)
Soman  (ISO)
sporidesmin A  (ISO)
sulforaphane  (EXP)
sunitinib  (ISO)
tamoxifen  (EXP)
temozolomide  (ISO)
tetrachloromethane  (ISO)
theaflavin  (EXP)
thimerosal  (ISO)
thioacetamide  (ISO)
thiram  (ISO)
titanium dioxide  (EXP)
topotecan  (ISO)
trichostatin A  (ISO)
valproic acid  (ISO)
vancomycin  (EXP)
vorinostat  (ISO)
XL147  (EXP)
zaragozic acid A  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
actin cytoskeleton organization  (ISO)
anterior/posterior pattern specification  (IGI)
BMP signaling pathway  (IGI)
bone trabecula formation  (IMP)
canonical Wnt signaling pathway  (IBA,IGI,ISO)
cellular response to BMP stimulus  (ISO)
cellular response to estradiol stimulus  (IEA)
cellular response to estrogen stimulus  (IDA,ISO)
cellular response to fibroblast growth factor stimulus  (IEA,ISO)
cellular response to growth factor stimulus  (ISO)
cellular response to heparin  (IEA,ISO)
cellular response to hypoxia  (IEA)
cellular response to interleukin-1  (IEA)
cellular response to prostaglandin E stimulus  (IEA,ISO)
cellular response to starvation  (IEA)
cellular response to transforming growth factor beta stimulus  (IEA)
cellular response to tumor necrosis factor  (IEA,ISO)
cellular response to vitamin D  (IEA)
cellular response to X-ray  (IDA)
convergent extension involved in somitogenesis  (IGI)
development of primary male sexual characteristics  (IGI)
digestive tract morphogenesis  (IGI)
dopaminergic neuron differentiation  (IDA)
dorsal/ventral axis specification  (IEA,ISO)
extrinsic apoptotic signaling pathway  (IMP)
female gonad development  (IGI)
hematopoietic progenitor cell differentiation  (ISO)
hematopoietic stem cell differentiation  (IEA,ISO)
hemopoiesis  (IMP)
male gonad development  (IGI)
negative regulation of androgen receptor signaling pathway  (IEA,ISO)
negative regulation of apoptotic process  (ISO)
negative regulation of B cell differentiation  (IMP,ISO)
negative regulation of BMP signaling pathway  (IGI)
negative regulation of bone remodeling  (IEA,ISO)
negative regulation of canonical Wnt signaling pathway  (IDA,IGI,ISO)
negative regulation of cell growth  (IEA,ISO)
negative regulation of cell migration  (IEA,ISO)
negative regulation of cell population proliferation  (ISO)
negative regulation of DNA-templated transcription  (IEA,ISO)
negative regulation of epithelial cell proliferation  (IEA,ISO)
negative regulation of epithelial to mesenchymal transition  (IEA,ISO)
negative regulation of fibroblast apoptotic process  (IEA,ISO)
negative regulation of fibroblast proliferation  (IEA,ISO)
negative regulation of gene expression  (IMP,ISO)
negative regulation of insulin secretion  (IEA,ISO)
negative regulation of JUN kinase activity  (IGI)
negative regulation of ossification  (IMP,ISO)
negative regulation of osteoblast differentiation  (IMP)
negative regulation of osteoblast proliferation  (IMP,ISO)
negative regulation of osteoclast differentiation  (IMP,ISO)
negative regulation of peptidyl-tyrosine phosphorylation  (ISO)
negative regulation of Wnt signaling pathway  (IGI,ISO)
neural crest cell fate commitment  (IMP)
neural tube closure  (IGI)
neural tube development  (IGI)
non-canonical Wnt signaling pathway  (IBA)
obsolete response to organic cyclic compound  (ISO)
osteoblast differentiation  (IEA)
osteoclast differentiation  (IMP)
positive regulation of apoptotic process  (ISO)
positive regulation of canonical Wnt signaling pathway  (IEA,ISO)
positive regulation of cell growth  (IEA,ISO)
positive regulation of cell population proliferation  (ISO)
positive regulation of DNA-templated transcription  (IEA,ISO)
positive regulation of epithelial cell proliferation  (ISO)
positive regulation of extrinsic apoptotic signaling pathway  (IMP)
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors  (IEA,ISO)
positive regulation of fat cell differentiation  (ISO)
positive regulation of fibroblast apoptotic process  (IEA,ISO)
positive regulation of non-canonical Wnt signaling pathway  (IEA,ISO)
positive regulation of smoothened signaling pathway  (IEA,ISO)
positive regulation of type B pancreatic cell proliferation  (IEA,ISO)
positive regulation of Wnt signaling pathway  (ISO)
prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis  (IMP)
regulation of branching involved in prostate gland morphogenesis  (IMP)
regulation of cell cycle process  (IEA,ISO)
regulation of establishment of planar polarity  (IGI)
regulation of midbrain dopaminergic neuron differentiation  (IGI)
regulation of neuron projection development  (IDA)
regulation of ossification  (ISO)
response to xenobiotic stimulus  (IDA)
somatic stem cell population maintenance  (IMP)
somitogenesis  (IEP,IGI)
stromal-epithelial cell signaling involved in prostate gland development  (IEP)
substrate adhesion-dependent cell spreading  (ISO)
ureteric bud development  (IEP)
Wnt signaling pathway involved in somitogenesis  (IGI)
Wnt signaling pathway, planar cell polarity pathway  (IDA)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Secreted and transmembrane wnt inhibitors and activators. Cruciat CM and Niehrs C, Cold Spring Harb Perspect Biol. 2013 Mar 1;5(3):a015081. doi: 10.1101/cshperspect.a015081.
2. Identification of genes differentially expressed in testes containing carcinoma in situ. Hoei-Hansen CE, etal., Mol Hum Reprod. 2004 Jun;10(6):423-31.
3. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
4. Identifying mRNA targets of microRNA dysregulated in cancer: with application to clear cell Renal Cell Carcinoma. Liu H, etal., BMC Syst Biol. 2010 Apr 27;4:51.
5. Overexpression of the Wnt5b gene in leiomyoma cells: implications for a role of the Wnt signaling pathway in the uterine benign tumor. Mangioni S, etal., J Clin Endocrinol Metab. 2005 Sep;90(9):5349-55. Epub 2005 Jun 21.
6. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
7. MGDs mouse GO annotations MGD data from the GO Consortium
8. MGD IEA MGD IEA
9. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
10. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
11. Mouse MP Annotation Import Pipeline RGD automated import pipeline
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9096311   PMID:9192640   PMID:9671940   PMID:9739103   PMID:9853965   PMID:10349636   PMID:10640709   PMID:10654605   PMID:11042159   PMID:11076861   PMID:11335128   PMID:11731256  
PMID:11731265   PMID:12055200   PMID:12210517   PMID:12412008   PMID:12477932   PMID:12490556   PMID:12812787   PMID:12815618   PMID:14581414   PMID:14681479   PMID:14976225   PMID:15306229  
PMID:15457338   PMID:15476588   PMID:15489334   PMID:15634693   PMID:15782199   PMID:15809042   PMID:15880404   PMID:16141072   PMID:16141073   PMID:16149051   PMID:16288033   PMID:16467359  
PMID:16545622   PMID:16567562   PMID:16575902   PMID:16602821   PMID:16672052   PMID:16849540   PMID:16920270   PMID:16942767   PMID:17044082   PMID:17158062   PMID:17287250   PMID:17389379  
PMID:17462603   PMID:17481602   PMID:17485441   PMID:17644613   PMID:17720858   PMID:18156211   PMID:18255031   PMID:18257070   PMID:18287559   PMID:18322704   PMID:18351676   PMID:18371946  
PMID:18392598   PMID:18403408   PMID:18498122   PMID:18521945   PMID:18554416   PMID:18565209   PMID:18729207   PMID:18941195   PMID:19100252   PMID:19185060   PMID:19188438   PMID:19223557  
PMID:19254787   PMID:19282366   PMID:19285468   PMID:19300477   PMID:19301255   PMID:19369394   PMID:19473496   PMID:19515997   PMID:19562671   PMID:19664990   PMID:19778523   PMID:19799774  
PMID:19850029   PMID:19896444   PMID:19924825   PMID:20027618   PMID:20130188   PMID:20185815   PMID:20308569   PMID:20595636   PMID:20887955   PMID:20890044   PMID:21041481   PMID:21150899  
PMID:21267068   PMID:21478884   PMID:21490069   PMID:21586556   PMID:21731673   PMID:21779340   PMID:21799872   PMID:21806977   PMID:21836067   PMID:21858105   PMID:21873635   PMID:21896628  
PMID:22166339   PMID:22173065   PMID:22235033   PMID:22290867   PMID:22359602   PMID:22371338   PMID:22535492   PMID:22863011   PMID:22928951   PMID:23022129   PMID:23044044   PMID:23087175  
PMID:23213461   PMID:23261541   PMID:23288785   PMID:23349620   PMID:23376422   PMID:23469192   PMID:23531410   PMID:23827310   PMID:24006456   PMID:24038862   PMID:24055172   PMID:24080158  
PMID:24140542   PMID:24278461   PMID:24339864   PMID:24523460   PMID:24590292   PMID:24885183   PMID:24952961   PMID:25212222   PMID:25253698   PMID:25456500   PMID:25669938   PMID:25788689  
PMID:25809273   PMID:25827793   PMID:25920569   PMID:26235626   PMID:26288816   PMID:26371318   PMID:26450967   PMID:26859490   PMID:27395006   PMID:27445154   PMID:27671872   PMID:27713059  
PMID:28009287   PMID:28250050   PMID:28287088   PMID:28292423   PMID:28400434   PMID:28535371   PMID:28605600   PMID:28687085   PMID:28894084   PMID:29196093   PMID:29215727   PMID:29463648  
PMID:29513653   PMID:30065628   PMID:30084950   PMID:30146317   PMID:30586565   PMID:30635555   PMID:31118232   PMID:31257105   PMID:31308530   PMID:32198470   PMID:32325033   PMID:32553120  
PMID:32571845   PMID:32715478   PMID:33109217   PMID:34321999   PMID:34569685   PMID:34929134   PMID:35132078   PMID:35175194   PMID:35210419   PMID:35383354   PMID:35689817   PMID:35831952  
PMID:35950533   PMID:35998637   PMID:36762637   PMID:36960826   PMID:37227818   PMID:37298722   PMID:37545238   PMID:38212077   PMID:38355793   PMID:38554160   PMID:38722977   PMID:38748896  


Genomics

Comparative Map Data
Sfrp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39823,901,401 - 23,939,648 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl823,901,518 - 23,939,648 (+)EnsemblGRCm39 Ensembl
GRCm38823,411,383 - 23,449,632 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl823,411,502 - 23,449,632 (+)EnsemblGRCm38mm10GRCm38
MGSCv37824,521,974 - 24,560,104 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36824,877,063 - 24,915,177 (+)NCBIMGSCv36mm8
Celera824,905,624 - 24,944,019 (+)NCBICelera
Cytogenetic Map8A2NCBI
cM Map811.48NCBI
SFRP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38841,261,962 - 41,309,473 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl841,261,962 - 41,309,473 (-)EnsemblGRCh38hg38GRCh38
GRCh37841,119,481 - 41,166,992 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36841,238,635 - 41,286,137 (-)NCBINCBI36Build 36hg18NCBI36
Build 34841,238,635 - 41,286,137NCBI
Celera840,068,517 - 40,116,053 (-)NCBICelera
Cytogenetic Map8p11.21NCBI
HuRef839,647,919 - 39,695,566 (-)NCBIHuRef
CHM1_1841,167,412 - 41,215,102 (-)NCBICHM1_1
T2T-CHM13v2.0841,535,586 - 41,583,179 (-)NCBIT2T-CHM13v2.0
Sfrp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81675,278,325 - 75,316,736 (-)NCBIGRCr8
mRatBN7.21668,575,763 - 68,614,180 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1668,575,763 - 68,614,286 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1673,854,196 - 73,892,590 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01677,271,342 - 77,309,732 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01672,520,516 - 72,558,923 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01673,372,007 - 73,410,777 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1673,372,007 - 73,410,777 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01673,006,739 - 73,045,509 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41673,030,458 - 73,067,304 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11673,031,966 - 73,066,892 (-)NCBI
Celera1666,467,691 - 66,505,810 (-)NCBICelera
Cytogenetic Map16q12.5NCBI
Sfrp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555361,663,344 - 1,703,514 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555361,663,721 - 1,702,678 (+)NCBIChiLan1.0ChiLan1.0
SFRP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2759,714,926 - 59,762,921 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1835,432,207 - 35,480,221 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0840,507,027 - 40,555,053 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1837,956,423 - 38,001,865 (-)NCBIpanpan1.1PanPan1.1panPan2
SFRP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11624,262,451 - 24,306,162 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1624,261,946 - 24,302,964 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1624,766,734 - 24,810,532 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01626,010,215 - 26,053,984 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1626,010,215 - 26,053,974 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11624,382,043 - 24,425,801 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01624,943,898 - 24,987,804 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01624,995,596 - 25,039,359 (+)NCBIUU_Cfam_GSD_1.0
Sfrp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494347,320,083 - 47,364,001 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367851,276,420 - 1,321,017 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367851,276,478 - 1,320,397 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SFRP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1710,436,426 - 10,489,748 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11710,436,414 - 10,489,773 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21711,790,230 - 11,878,539 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SFRP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1839,243,775 - 39,289,050 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl839,243,780 - 39,288,984 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660522,558,131 - 2,612,751 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sfrp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247802,132,960 - 2,174,508 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247802,133,105 - 2,172,301 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Sfrp1
3221 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1039
Count of miRNA genes:555
Interacting mature miRNAs:691
Transcripts:ENSMUST00000033952
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1558870Eae36_mexperimental allergic encephalomyelitis susceptibility 36 (mouse)Not determined81477316071498244Mouse
1301298Pgia4_mproteoglycan induced arthritis 4 (mouse)Not determined81656937350569697Mouse
1300912Daq19_mdirectional asymmetry QTL 19 (mouse)Not determined81550657249506729Mouse
11532713Sluc42_msusceptibility to lung cancer 42 (mouse)81344721035321225Mouse
4142199Poats1_mpost-ovarectomy adrenal tumor susceptibility 1 (mouse)Not determined1708262628849467Mouse
1300603Cd8ts2_mCD8 T cell subset 2 (mouse)Not determined81945501853455150Mouse
4140978Nilac5_mnicotine induced locomotor activity 5 (mouse)Not determined8131773288Mouse
1301532Scc8_mcolon tumor susceptibility 8 (mouse)Not determined8721249935110107Mouse
10412209Cypr7_mcytokine production 7 (mouse)Not determined8810320142103372Mouse
1301088Alcw6_malcohol withdrawal 6 (mouse)Not determined81550657249506729Mouse
11533914Mts5_mmammary tumor susceptibility 5 (mouse)8130447432Mouse
13432571Scvg1_msubcutaneous vessel growth QTL 1 (mouse)8124751082Mouse
1300906Ap8q_malcohol preference 8 QTL (mouse)Not determined8798418941984342Mouse
1301929Eae24_msusceptibility to experimental allergic encephalomyelitis 24 (mouse)Not determined8810320142103372Mouse
27226756Femd2_mfemur midshaft diameter 2, 5 week (mouse)8495000035067154Mouse
1301128Sluc20_msusceptibility to lung cancer 20 (mouse)Not determined8810320142103372Mouse
1301160Eae14_msusceptibility to experimental allergic encephalomyelitis 14 (mouse)Not determined81945501853455150Mouse
1301550Fembrs2_mfemur breaking strength 2 (mouse)Not determined81832109752321225Mouse

Markers in Region
Sfrp1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv37824,556,800 - 24,557,756UniSTSGRCm37
MGSCv37824,556,798 - 24,557,756UniSTSGRCm37
MGSCv37824,559,804 - 24,560,049UniSTSGRCm37
Celera824,940,715 - 24,941,665UniSTS
Celera824,943,714 - 24,943,964UniSTS
Celera824,940,713 - 24,941,665UniSTS
Cytogenetic Map8A2UniSTS
cM Map89.5UniSTS
cM Map89.5UniSTS
AW742929  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38823,446,832 - 23,447,088UniSTSGRCm38
MGSCv37824,557,304 - 24,557,560UniSTSGRCm37
Celera824,941,219 - 24,941,469UniSTS
Cytogenetic Map8A2UniSTS
cM Map89.5UniSTS
Whitehead/MRC_RH8266.29UniSTS
AW011917  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38823,447,800 - 23,447,940UniSTSGRCm38
MGSCv37824,558,272 - 24,558,412UniSTSGRCm37
Celera824,942,181 - 24,942,321UniSTS
Cytogenetic Map8A2UniSTS
cM Map89.5UniSTS
Whitehead/MRC_RH8264.27UniSTS
AW107218  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38823,449,159 - 23,449,304UniSTSGRCm38
MGSCv37824,559,631 - 24,559,776UniSTSGRCm37
Celera824,943,541 - 24,943,686UniSTS
Cytogenetic Map8A2UniSTS
cM Map89.5UniSTS
Whitehead/MRC_RH8266.06UniSTS
RH141094  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38823,447,979 - 23,448,150UniSTSGRCm38
MGSCv37824,558,451 - 24,558,622UniSTSGRCm37
Celera824,942,360 - 24,942,531UniSTS
Cytogenetic Map8A2UniSTS
cM Map89.5UniSTS
Sfrp1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map8A2UniSTS
Sfrp1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38823,446,326 - 23,447,284UniSTSGRCm38
MGSCv37824,556,798 - 24,557,756UniSTSGRCm37
Celera824,940,713 - 24,941,665UniSTS
Cytogenetic Map8A2UniSTS
Sfrp1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38823,446,328 - 23,447,284UniSTSGRCm38
MGSCv37824,556,800 - 24,557,756UniSTSGRCm37
Celera824,940,715 - 24,941,665UniSTS
Cytogenetic Map8A2UniSTS
Sfrp1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map8A2UniSTS
cM Map89.5UniSTS
Sfrp1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map8A2UniSTS
Sfrp1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38823,449,332 - 23,449,577UniSTSGRCm38
MGSCv37824,559,804 - 24,560,049UniSTSGRCm37
Celera824,943,714 - 24,943,964UniSTS
Cytogenetic Map8A2UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000033952   ⟹   ENSMUSP00000033952
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl823,901,518 - 23,939,648 (+)Ensembl
GRCm38.p6 Ensembl823,411,502 - 23,449,632 (+)Ensembl
RefSeq Acc Id: NM_013834   ⟹   NP_038862
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39823,901,518 - 23,939,648 (+)NCBI
GRCm38823,411,502 - 23,449,632 (+)NCBI
MGSCv37824,521,974 - 24,560,104 (+)RGD
Celera824,905,624 - 24,944,019 (+)RGD
cM Map8 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_011242128   ⟹   XP_011240430
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39823,901,401 - 23,939,648 (+)NCBI
GRCm38823,411,383 - 23,449,632 (+)NCBI
Sequence:
RefSeq Acc Id: NP_038862   ⟸   NM_013834
- Peptide Label: precursor
- UniProtKB: Q8C4U3 (UniProtKB/Swiss-Prot),   Q505A2 (UniProtKB/Swiss-Prot),   O08861 (UniProtKB/Swiss-Prot),   Q8R1J4 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011240430   ⟸   XM_011242128
- Peptide Label: isoform X1
- UniProtKB: Q8C4U3 (UniProtKB/Swiss-Prot),   Q505A2 (UniProtKB/Swiss-Prot),   O08861 (UniProtKB/Swiss-Prot),   Q8R1J4 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000033952   ⟸   ENSMUST00000033952
Protein Domains
FZ   NTR

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8C4U3-F1-model_v2 AlphaFold Q8C4U3 1-314 view protein structure

Promoters
RGD ID:8666717
Promoter ID:EPDNEW_M11390
Type:multiple initiation site
Name:Sfrp1_1
Description:Mus musculus secreted frizzled-related protein 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38823,411,500 - 23,411,560EPDNEW
RGD ID:6843700
Promoter ID:MM_KWN:53966
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:ES_Cell,   Kidney
Transcripts:OTTMUST00000049933
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36824,521,701 - 24,522,201 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:892014 AgrOrtholog
Ensembl Genes ENSMUSG00000031548 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000033952 ENTREZGENE
  ENSMUST00000033952.8 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.2000.10 UniProtKB/Swiss-Prot
  2.40.50.120 UniProtKB/Swiss-Prot
InterPro Frizzled/SFRP UniProtKB/Swiss-Prot
  Frizzled_dom UniProtKB/Swiss-Prot
  Frizzled_dom_sf UniProtKB/Swiss-Prot
  Netrin_domain UniProtKB/Swiss-Prot
  Netrin_module_non-TIMP UniProtKB/Swiss-Prot
  SFRP1_CRD UniProtKB/Swiss-Prot
  TIMP-like_OB-fold UniProtKB/Swiss-Prot
KEGG Report mmu:20377 UniProtKB/Swiss-Prot
MGD MGI:892014 ENTREZGENE
NCBI Gene 20377 ENTREZGENE
PANTHER PTHR11309 UniProtKB/Swiss-Prot
  PTHR11309:SF87 UniProtKB/Swiss-Prot
Pfam NTR UniProtKB/Swiss-Prot
  PF01392 UniProtKB/Swiss-Prot
PhenoGen Sfrp1 PhenoGen
PROSITE NTR UniProtKB/Swiss-Prot
  PS50038 UniProtKB/Swiss-Prot
SMART C345C UniProtKB/Swiss-Prot
  FRI UniProtKB/Swiss-Prot
Superfamily-SCOP SSF50242 UniProtKB/Swiss-Prot
  SSF63501 UniProtKB/Swiss-Prot
UniProt O08861 ENTREZGENE
  Q505A2 ENTREZGENE
  Q8C4U3 ENTREZGENE
  Q8R1J4 ENTREZGENE
  SFRP1_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary O08861 UniProtKB/Swiss-Prot
  Q505A2 UniProtKB/Swiss-Prot
  Q8R1J4 UniProtKB/Swiss-Prot