|
G
|
Ahr
|
aryl hydrocarbon receptor
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multiple interactions
|
ISO EXP
|
iprodione binds to and results in increased activity of AHR protein
|
CTD |
PMID:14636698 |
|
NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901
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|
G
|
Aldh2
|
aldehyde dehydrogenase 2 family member
|
multiple interactions
|
ISO
|
[Maneb co-treated with mancozeb co-treated with iprodione co-treated with enilconazole co-treated with Chlorpyrifos co-treated with Diazinon co-treated with Dimethoate] results in decreased expression of ALDH2 mRNA; [Maneb co-treated with mancozeb co-treated with iprodione co-treated with enilconazole co-treated with Chlorpyrifos co-treated with Diazinon co-treated with Dimethoate] results in decreased expression of and results in decreased activity of ALDH2 protein
|
CTD |
PMID:34830855 |
|
NCBI chr12:40,610,244...40,643,220
Ensembl chr12:40,610,224...40,643,219
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|
G
|
Anxa10
|
annexin A10
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increases expression
|
ISO
|
iprodione results in increased expression of ANXA10 mRNA
|
CTD |
PMID:32194361 |
|
NCBI chr16:32,505,025...32,571,961
Ensembl chr16:32,467,126...32,571,961
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G
|
Ar
|
androgen receptor
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multiple interactions affects binding
|
ISO
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[iprodione binds to and results in decreased activity of AR protein] inhibits the reaction [Metribolone binds to AR protein]; iprodione inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; iprodione inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein] iprodione binds to AR protein
|
CTD |
PMID:19564212 PMID:33049310 |
|
NCBI chr X:67,135,317...67,304,476
Ensembl chr X:67,135,317...67,304,467
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G
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Bcl2
|
BCL2, apoptosis regulator
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decreases expression multiple interactions
|
EXP
|
iprodione results in decreased expression of BCL2 protein Chlorpyrifos promotes the reaction [iprodione results in decreased expression of BCL2 protein]; iprodione promotes the reaction [Chlorpyrifos results in decreased expression of BCL2 protein]
|
CTD |
PMID:33586219 PMID:34060014 |
|
NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
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G
|
Casp3
|
caspase 3
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increases expression multiple interactions
|
EXP
|
iprodione results in increased expression of CASP3 protein Chlorpyrifos promotes the reaction [iprodione results in increased expression of CASP3 protein]; iprodione promotes the reaction [Chlorpyrifos results in increased expression of CASP3 protein]
|
CTD |
PMID:33586219 PMID:34060014 |
|
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
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G
|
Cdh1
|
cadherin 1
|
multiple interactions
|
ISO
|
[procymidone co-treated with iprodione co-treated with cyprodinil co-treated with fludioxonil co-treated with cyhalothrin co-treated with 4-hydroxy-2-nonenal] results in decreased expression of CDH1 protein; [procymidone co-treated with iprodione co-treated with cyprodinil co-treated with fludioxonil co-treated with cyhalothrin] results in decreased expression of CDH1 protein
|
CTD |
PMID:34503147 |
|
NCBI chr19:51,402,178...51,471,572
Ensembl chr19:51,402,034...51,471,565
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|
G
|
Cldn11
|
claudin 11
|
increases expression multiple interactions
|
EXP
|
iprodione results in increased expression of CLDN11 protein [carbendazim co-treated with iprodione] results in decreased expression of CLDN11 protein
|
CTD |
PMID:28576679 |
|
NCBI chr 2:114,136,234...114,149,539
Ensembl chr 2:114,136,234...114,149,539
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G
|
Cyp19a1
|
cytochrome P450, family 19, subfamily a, polypeptide 1
|
increases activity
|
ISO
|
iprodione results in increased activity of CYP19A1 protein
|
CTD |
PMID:11884232 |
|
NCBI chr 8:63,449,148...63,476,534
Ensembl chr 8:63,449,148...63,476,917
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G
|
Cyp1a1
|
cytochrome P450, family 1, subfamily a, polypeptide 1
|
increases expression
|
ISO
|
iprodione results in increased expression of CYP1A1 mRNA; iprodione results in increased expression of CYP1A1 protein
|
CTD |
PMID:16696176 PMID:32194361 |
|
NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
|
|
G
|
Cyp2c6
|
cytochrome P450, family 2, subfamily C, polypeptide 6
|
decreases expression
|
ISO
|
iprodione results in decreased expression of CYP2C19 protein
|
CTD |
PMID:32194361 |
|
NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:247,879,078...247,916,798
|
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G
|
Cyp3a2
|
cytochrome P450, family 3, subfamily a, polypeptide 2
|
multiple interactions
|
ISO
|
[procymidone co-treated with iprodione co-treated with cyprodinil co-treated with fludioxonil co-treated with cyhalothrin] results in increased expression of CYP3A4 mRNA
|
CTD |
PMID:25028461 |
|
NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857
|
|
G
|
Cyp7a1
|
cytochrome P450 family 7 subfamily A member 1
|
decreases expression
|
ISO
|
iprodione results in decreased expression of CYP7A1 protein
|
CTD |
PMID:32194361 |
|
NCBI chr 5:24,174,505...24,184,202
Ensembl chr 5:24,174,505...24,184,202
|
|
G
|
Ddit3
|
DNA-damage inducible transcript 3
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increases expression
|
ISO
|
iprodione results in increased expression of DDIT3 mRNA
|
CTD |
PMID:16696176 |
|
NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509
|
|
G
|
Esr1
|
estrogen receptor 1
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multiple interactions
|
ISO
|
iprodione binds to and results in increased activity of ESR1 protein
|
CTD |
PMID:33049310 |
|
NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354
|
|
G
|
Esr2
|
estrogen receptor 2
|
multiple interactions
|
ISO
|
iprodione binds to and results in increased activity of ESR2 protein
|
CTD |
PMID:33049310 |
|
NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:100,545,206...100,644,709
|
|
G
|
Fos
|
Fos proto-oncogene, AP-1 transcription factor subunit
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increases expression
|
ISO
|
iprodione results in increased expression of FOS mRNA
|
CTD |
PMID:16696176 |
|
NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598
|
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G
|
Fshb
|
follicle stimulating hormone subunit beta
|
multiple interactions decreases expression
|
EXP
|
Chlorpyrifos inhibits the reaction [iprodione results in decreased expression of FSHB protein]; iprodione inhibits the reaction [Chlorpyrifos results in decreased expression of FSHB protein]; iprodione promotes the reaction [Chlorpyrifos results in decreased expression of FSHB protein]
|
CTD |
PMID:33586219 PMID:34060014 |
|
NCBI chr 3:114,003,262...114,007,072
Ensembl chr 3:114,003,262...114,007,072
|
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G
|
Gadd45a
|
growth arrest and DNA-damage-inducible, alpha
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increases expression
|
ISO
|
iprodione results in increased expression of GADD45A mRNA
|
CTD |
PMID:16696176 |
|
NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:97,484,502...97,486,807
|
|
G
|
Gja1
|
gap junction protein, alpha 1
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multiple interactions
|
EXP
|
[carbendazim co-treated with iprodione] results in decreased expression of GJA1 protein
|
CTD |
PMID:28576679 |
|
NCBI chr20:36,302,490...36,315,010
Ensembl chr20:36,302,352...36,319,689
|
|
G
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Gsta2
|
glutathione S-transferase alpha 2
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increases expression
|
ISO
|
iprodione results in increased expression of GSTA2 mRNA
|
CTD |
PMID:16696176 |
|
NCBI chr 8:88,064,829...88,077,168
Ensembl chr 8:88,064,616...88,077,092
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G
|
H2ax
|
H2A.X variant histone
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multiple interactions
|
ISO
|
[fludioxonil co-treated with cyprodinil co-treated with procymidone co-treated with iprodione co-treated with cyhalothrin] results in increased phosphorylation of H2AX protein; [Maneb co-treated with mancozeb co-treated with iprodione co-treated with enilconazole co-treated with Chlorpyrifos co-treated with Diazinon co-treated with Dimethoate] results in increased expression of H2AX protein; [procymidone co-treated with iprodione co-treated with cyprodinil co-treated with fludioxonil co-treated with cyhalothrin co-treated with 4-hydroxy-2-nonenal] results in increased expression of H2AX protein; [procymidone co-treated with iprodione co-treated with cyprodinil co-treated with fludioxonil co-treated with cyhalothrin] results in increased expression of H2AX protein
|
CTD |
PMID:22389207 PMID:34503147 PMID:34830855 |
|
NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079
|
|
G
|
Hsd17b3
|
hydroxysteroid (17-beta) dehydrogenase 3
|
multiple interactions decreases expression
|
EXP
|
[Chlorpyrifos co-treated with iprodione] results in decreased expression of HSD17B3 mRNA; [iprodione co-treated with Chlorpyrifos] results in decreased expression of HSD17B3 mRNA iprodione results in decreased expression of HSD17B3 mRNA
|
CTD |
PMID:33586219 PMID:34060014 |
|
NCBI chr17:1,032,958...1,064,283
Ensembl chr17:1,032,958...1,064,283
|
|
G
|
Hspa5
|
heat shock protein family A (Hsp70) member 5
|
increases expression
|
ISO
|
iprodione results in increased expression of HSPA5 mRNA
|
CTD |
PMID:16696176 |
|
NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:38,453,041...38,458,790
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G
|
Lhb
|
luteinizing hormone subunit beta
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multiple interactions decreases expression
|
EXP
|
Chlorpyrifos inhibits the reaction [iprodione results in decreased expression of LHB protein]; iprodione inhibits the reaction [Chlorpyrifos results in decreased expression of LHB protein]
|
CTD |
PMID:34060014 |
|
NCBI chr 1:105,037,457...105,038,446
Ensembl chr 1:105,037,457...105,038,445
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G
|
Nr1i2
|
nuclear receptor subfamily 1, group I, member 2
|
multiple interactions
|
ISO
|
[procymidone co-treated with iprodione co-treated with cyprodinil co-treated with fludioxonil co-treated with cyhalothrin] results in increased activity of NR1I2 protein; iprodione binds to and results in increased activity of NR1I2 protein
|
CTD |
PMID:25028461 PMID:33049310 |
|
NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380
|
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G
|
Nr5a1
|
nuclear receptor subfamily 5, group A, member 1
|
decreases expression multiple interactions
|
EXP
|
iprodione results in decreased expression of NR5A1 mRNA [iprodione co-treated with Chlorpyrifos] results in decreased expression of NR5A1 mRNA; iprodione promotes the reaction [Chlorpyrifos results in decreased expression of NR5A1 mRNA]
|
CTD |
PMID:33586219 PMID:34060014 |
|
NCBI chr 3:42,874,505...42,896,109
Ensembl chr 3:42,875,221...42,896,046
|
|
G
|
Pparg
|
peroxisome proliferator-activated receptor gamma
|
increases activity multiple interactions
|
ISO
|
iprodione results in increased activity of PPARG protein iprodione binds to and results in increased activity of PPARG protein
|
CTD |
PMID:20143881 PMID:33049310 |
|
NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104
|
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G
|
Ppargc1a
|
PPARG coactivator 1 alpha
|
decreases expression multiple interactions
|
EXP
|
iprodione results in decreased expression of PPARGC1A mRNA Chlorpyrifos promotes the reaction [iprodione results in decreased expression of PPARGC1A mRNA]; iprodione promotes the reaction [Chlorpyrifos results in decreased expression of PPARGC1A mRNA]
|
CTD |
PMID:33586219 PMID:34060014 |
|
NCBI chr14:63,073,505...63,729,215
Ensembl chr14:63,273,189...63,729,213
|
|
G
|
Sirt1
|
sirtuin 1
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multiple interactions decreases expression
|
EXP
|
[iprodione co-treated with Chlorpyrifos] results in decreased expression of SIRT1 mRNA; iprodione promotes the reaction [Chlorpyrifos results in decreased expression of SIRT1 mRNA] iprodione results in decreased expression of SIRT1 mRNA
|
CTD |
PMID:33586219 PMID:34060014 |
|
NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,305,476...25,328,000
|
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G
|
Stmn1
|
stathmin 1
|
increases expression
|
EXP
|
iprodione results in increased expression of STMN1 mRNA
|
CTD |
PMID:28576679 |
|
NCBI chr 5:151,964,308...151,970,843
Ensembl chr 5:151,964,351...151,970,842
|
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G
|
Tert
|
telomerase reverse transcriptase
|
multiple interactions decreases expression
|
EXP
|
[Chlorpyrifos co-treated with iprodione] results in decreased expression of TERT mRNA; [iprodione co-treated with Chlorpyrifos] results in decreased expression of TERT mRNA iprodione results in decreased expression of TERT mRNA
|
CTD |
PMID:33586219 PMID:34060014 |
|
NCBI chr 1:31,465,766...31,488,650
Ensembl chr 1:31,466,056...31,488,111
|
|
G
|
Thra
|
thyroid hormone receptor alpha
|
multiple interactions
|
ISO
|
iprodione binds to and results in increased activity of THRA protein
|
CTD |
PMID:33049310 |
|
NCBI chr10:84,198,141...84,225,659
Ensembl chr10:84,197,011...84,225,657
|
|
G
|
Thrb
|
thyroid hormone receptor beta
|
multiple interactions
|
ISO
|
iprodione binds to and results in increased activity of THRB protein
|
CTD |
PMID:33049310 |
|
NCBI chr15:10,115,954...10,465,231
Ensembl chr15:10,115,954...10,313,680
|
|
G
|
Tnf
|
tumor necrosis factor
|
multiple interactions
|
ISO
|
Acetylcysteine inhibits the reaction [iprodione inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]]; iprodione inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]
|
CTD |
PMID:33226166 |
|
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
|
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G
|
Tp53bp1
|
tumor protein p53 binding protein 1
|
multiple interactions
|
ISO
|
[procymidone co-treated with iprodione co-treated with cyprodinil co-treated with fludioxonil co-treated with cyhalothrin co-treated with 4-hydroxy-2-nonenal] affects the expression of TP53BP1 protein; [procymidone co-treated with iprodione co-treated with cyprodinil co-treated with fludioxonil co-treated with cyhalothrin] affects the expression of TP53BP1 protein
|
CTD |
PMID:34503147 |
|
NCBI chr 3:128,620,320...128,724,716
Ensembl chr 3:128,620,322...128,696,747
|
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