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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:hexane
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Accession:CHEBI:29021 term browser browse the term
Definition:An unbranched alkane containing six carbon atoms.
Synonyms:related_synonym: CH3-[CH2]4-CH3;   Formula=C6H14;   Hexan;   InChI=1S/C6H14/c1-3-5-6-4-2/h3-6H2,1-2H3;   InChIKey=VLKZOEOYAKHREP-UHFFFAOYSA-N;   SMILES=CCCCCC;   n-Hexane
 alt_id: CHEBI:10606;   CHEBI:24566;   CHEBI:24568;   CHEBI:43148
 xref: Beilstein:1730733;   CAS:110-54-3;   DrugBank:DB02764;   Gmelin:1985;   HMDB:HMDB0029600;   KEGG:C11271;   LIPID_MAPS_instance:LMFA11000007
 xref_mesh: MESH:C026385
 xref: PDBeChem:HEX;   PMID:11292478;   PMID:11684179;   PMID:11886809;   PMID:15325316;   PMID:18231777;   PMID:19229957;   PMID:19384711;   PMID:23452516;   PMID:23567114;   PMID:23620851;   PMID:23740543;   PMID:23822317;   PMID:23931182;   PMID:7612176;   Reaxys:1730733;   Wikipedia:Hexane


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hexane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenoceptor beta 1 multiple interactions ISO [Particulate Matter co-treated with n-hexane] results in decreased expression of ADRB1 mRNA CTD PMID:30503853 NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259 		JBrowse link
G Adrb2 adrenoceptor beta 2 multiple interactions ISO [Particulate Matter co-treated with n-hexane] results in decreased expression of ADRB2 mRNA CTD PMID:30503853 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512 		JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B1 increases expression ISO n-hexane results in increased expression of AKR1B1 mRNA CTD PMID:20566472 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157 		JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases expression ISO n-hexane results in increased expression of AKR1B10 mRNA CTD PMID:20566472 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852 		JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 increases expression ISO n-hexane results in increased expression of AKR1C1 mRNA CTD PMID:20566472 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326 		JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 increases expression ISO n-hexane results in increased expression of AKR1C3 mRNA CTD PMID:20566472 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873 		JBrowse link
G Alpl alkaline phosphatase, biomineralization associated decreases methylation EXP n-hexane results in decreased methylation of ALPL promoter CTD PMID:23740543 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446 		JBrowse link
G Areg amphiregulin decreases methylation EXP n-hexane results in decreased methylation of AREG promoter CTD PMID:23740543 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535 		JBrowse link
G Arhgap45 Rho GTPase activating protein 45 increases methylation EXP n-hexane results in increased methylation of ARHGAP45 promoter CTD PMID:23740543 NCBI chr 7:9,674,873...9,690,286
Ensembl chr 7:9,674,897...9,690,268 		JBrowse link
G Atl2 atlastin GTPase 2 decreases methylation EXP n-hexane results in decreased methylation of ATL2 promoter CTD PMID:23740543 NCBI chr 6:15,139,071...15,180,421
Ensembl chr 6:15,139,044...15,180,421 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression EXP n-hexane metabolite results in increased expression of BAX protein CTD PMID:17492505 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression EXP n-hexane metabolite results in increased expression of BCL2 protein CTD PMID:17492505 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bclaf1 BCL2-associated transcription factor 1 decreases methylation EXP n-hexane results in decreased methylation of BCLAF1 promoter CTD PMID:23740543 NCBI chr 1:15,088,436...15,117,666
Ensembl chr 1:15,070,894...15,148,832 		JBrowse link
G C16h19orf44 similar to human chromosome 19 open reading frame 44 increases methylation EXP n-hexane results in increased methylation of C16H19ORF44 promoter CTD PMID:23740543 NCBI chr16:17,379,999...17,396,088
Ensembl chr16:17,380,003...17,396,002 		JBrowse link
G Calr3 calreticulin 3 increases methylation EXP n-hexane results in increased methylation of CALR3 promoter CTD PMID:23740543 NCBI chr16:17,396,064...17,423,166
Ensembl chr16:17,396,247...17,423,015 		JBrowse link
G Cap1 cyclase associated actin cytoskeleton regulatory protein 1 decreases methylation EXP n-hexane results in decreased methylation of CAP1 promoter CTD PMID:23740543 NCBI chr 5:135,142,108...135,168,885
Ensembl chr 5:135,142,112...135,168,769 		JBrowse link
G Casp3 caspase 3 increases expression EXP n-hexane metabolite results in increased expression of CASP3 protein CTD PMID:17492505 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Ccnk cyclin K decreases methylation EXP n-hexane results in decreased methylation of CCNK promoter CTD PMID:23740543 NCBI chr 6:127,090,115...127,113,195
Ensembl chr 6:127,090,569...127,113,191 		JBrowse link
G Cfap20 cilia and flagella associated protein 20 decreases methylation EXP n-hexane results in decreased methylation of CFAP20 promoter CTD PMID:23740543 NCBI chr19:9,608,867...9,622,558
Ensembl chr19:9,608,859...9,622,558 		JBrowse link
G Chic2 cysteine-rich hydrophobic domain 2 decreases methylation EXP n-hexane results in decreased methylation of CHIC2 promoter CTD PMID:23740543 NCBI chr14:33,157,669...33,192,015
Ensembl chr14:33,157,537...33,191,895 		JBrowse link
G Chmp2a charged multivesicular body protein 2A decreases methylation EXP n-hexane results in decreased methylation of CHMP2A promoter CTD PMID:23740543 NCBI chr 1:73,660,045...73,662,894
Ensembl chr 1:73,660,046...73,662,452 		JBrowse link
G Clcn2 chloride voltage-gated channel 2 decreases methylation EXP n-hexane results in decreased methylation of CLCN2 promoter CTD PMID:23740543 NCBI chr11:80,197,741...80,211,657
Ensembl chr11:80,198,153...80,211,657 		JBrowse link
G Coprs coordinator of PRMT5 and differentiation stimulator decreases methylation EXP n-hexane results in decreased methylation of COPRS promoter CTD PMID:23740543 NCBI chr16:75,721,264...75,726,375
Ensembl chr16:75,720,061...75,726,375 		JBrowse link
G Copz2 COPI coat complex subunit zeta 2 decreases methylation EXP n-hexane results in decreased methylation of COPZ2 promoter CTD PMID:23740543 NCBI chr10:81,832,441...81,845,514
Ensembl chr10:81,832,418...81,845,514 		JBrowse link
G Crppa CDP-L-ribitol pyrophosphorylase A decreases methylation EXP n-hexane results in decreased methylation of CRPPA promoter CTD PMID:23740543 NCBI chr 6:53,120,264...53,397,030
Ensembl chr 6:53,121,438...53,397,028 		JBrowse link
G Cspg4 chondroitin sulfate proteoglycan 4 increases methylation EXP n-hexane results in increased methylation of CSPG4 promoter CTD PMID:23740543 NCBI chr 8:57,264,962...57,300,010
Ensembl chr 8:57,264,962...57,300,010 		JBrowse link
G Cthrc1 collagen triple helix repeat containing 1 decreases methylation EXP n-hexane results in decreased methylation of CTHRC1 promoter CTD PMID:23740543 NCBI chr 7:70,122,474...70,132,756
Ensembl chr 7:70,122,474...70,132,756 		JBrowse link
G Cul4a cullin 4A decreases methylation EXP n-hexane results in decreased methylation of CUL4A promoter CTD PMID:23740543 NCBI chr16:76,385,298...76,422,316
Ensembl chr16:76,384,546...76,422,330 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 affects expression
affects methylation		 EXP n-hexane affects the expression of CYP11A1 mRNA; n-hexane affects the expression of CYP11A1 protein
n-hexane affects the methylation of CYP11A1 promoter		 CTD PMID:26410608 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 affects expression
affects methylation		 EXP n-hexane affects the expression of CYP17A1 mRNA; n-hexane affects the expression of CYP17A1 protein
n-hexane affects the methylation of CYP17A1 promoter		 CTD PMID:26410608 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases hydroxylation
multiple interactions		 EXP CYP1A1 protein results in increased hydroxylation of n-hexane
diallyl trisulfide promotes the reaction [n-hexane results in increased expression of and results in increased activity of CYP1A1 protein]; n-hexane results in increased expression of and results in increased activity of CYP1A1 protein		 CTD PMID:16484137 PMID:28115069 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases hydroxylation
multiple interactions		 EXP CYP1A2 protein results in increased hydroxylation of n-hexane
diallyl trisulfide inhibits the reaction [n-hexane results in increased expression of CYP1A2 protein]; n-hexane results in increased expression of and results in increased activity of CYP1A2 protein		 CTD PMID:16484137 PMID:28115069 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions
increases activity		 EXP diallyl trisulfide inhibits the reaction [n-hexane results in increased activity of CYP2B1 protein] CTD PMID:28115069 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases hydroxylation ISO CYP2B1 protein results in increased hydroxylation of n-hexane; CYP2B6 protein results in increased hydroxylation of n-hexane CTD PMID:16484137 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 affects response to substance
multiple interactions
increases metabolic processing
increases hydroxylation		 ISO
EXP		 CYP2E1 gene polymorphism affects the susceptibility to n-hexane
diallyl trisulfide inhibits the reaction [n-hexane results in increased expression of and results in increased activity of CYP2E1 protein]; n-hexane results in increased expression of and results in increased activity of CYP2E1 protein
CYP2E1 protein results in increased metabolism of n-hexane
CYP2E1 protein results in increased hydroxylation of n-hexane		 CTD PMID:11201664 PMID:16484137 PMID:28115069 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Dip2c disco-interacting protein 2 homolog C decreases methylation EXP n-hexane results in decreased methylation of DIP2C promoter CTD PMID:23740543 NCBI chr17:60,647,346...61,032,467
Ensembl chr17:60,649,065...61,032,305 		JBrowse link
G Dnmt1 DNA methyltransferase 1 decreases methylation EXP n-hexane results in decreased methylation of DNMT1 promoter CTD PMID:23740543 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659 		JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha decreases methylation EXP n-hexane results in decreased methylation of DNMT3A promoter CTD PMID:23740543 NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687 		JBrowse link
G Dnttip1 deoxynucleotidyltransferase, terminal, interacting protein 1 decreases methylation EXP n-hexane results in decreased methylation of DNTTIP1 promoter CTD PMID:23740543 NCBI chr 3:153,481,718...153,505,403
Ensembl chr 3:153,481,705...153,505,759 		JBrowse link
G Drd5 dopamine receptor D5 decreases methylation EXP n-hexane results in decreased methylation of DRD5 promoter CTD PMID:23740543 NCBI chr14:72,487,950...72,491,050
Ensembl chr14:72,489,347...72,490,774 		JBrowse link
G E2f3 E2F transcription factor 3 decreases methylation EXP n-hexane results in decreased methylation of E2F3 promoter CTD PMID:23740543 NCBI chr17:34,601,756...34,679,139
Ensembl chr17:34,601,830...34,676,253 		JBrowse link
G Epn3 epsin 3 decreases methylation EXP n-hexane results in decreased methylation of EPN3 promoter CTD PMID:23740543 NCBI chr10:79,438,978...79,449,516
Ensembl chr10:79,438,978...79,447,356 		JBrowse link
G Fam20a FAM20A, golgi associated secretory pathway pseudokinase increases methylation EXP n-hexane results in increased methylation of FAM20A promoter CTD PMID:23740543 NCBI chr10:94,638,836...94,697,814
Ensembl chr10:94,642,850...94,697,672 		JBrowse link
G Fech ferrochelatase increases expression ISO n-hexane results in increased expression of FECH mRNA CTD PMID:20566472 NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348 		JBrowse link
G Fgfbp1 fibroblast growth factor binding protein 1 decreases methylation EXP n-hexane results in decreased methylation of FGFBP1 promoter CTD PMID:23740543 NCBI chr14:67,103,686...67,107,492
Ensembl chr14:67,104,545...67,107,496 		JBrowse link
G Fjx1 four-jointed box kinase 1 decreases methylation EXP n-hexane results in decreased methylation of FJX1 promoter CTD PMID:23740543 NCBI chr 3:88,774,220...88,776,321
Ensembl chr 3:88,774,220...88,776,321 		JBrowse link
G Fmo3 flavin containing dimethylaniline monoxygenase 3 decreases methylation EXP n-hexane results in decreased methylation of FMO3 promoter CTD PMID:23740543 NCBI chr13:75,309,367...75,334,915
Ensembl chr13:75,309,374...75,328,028 		JBrowse link
G Foxi1 forkhead box I1 decreases methylation EXP n-hexane results in decreased methylation of FOXI1 promoter CTD PMID:23740543 NCBI chr10:18,806,292...18,810,231
Ensembl chr10:18,806,308...18,810,231 		JBrowse link
G Ftl1 ferritin light chain 1 increases expression ISO n-hexane results in increased expression of FTL mRNA CTD PMID:20566472 NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725
Ensembl chr10:95,936,387...95,939,725 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase increases expression ISO n-hexane results in increased expression of G6PD mRNA CTD PMID:20566472 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801 		JBrowse link
G Galnt17 polypeptide N-acetylgalactosaminyltransferase 17 decreases methylation EXP n-hexane results in decreased methylation of GALNT17 promoter CTD PMID:23740543 NCBI chr12:25,323,230...25,781,897
Ensembl chr12:25,322,701...25,781,290 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO n-hexane results in increased expression of GCLC mRNA CTD PMID:20566472 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO n-hexane results in increased expression of GCLM mRNA CTD PMID:20566472 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G Glrx2 glutaredoxin 2 decreases methylation EXP n-hexane results in decreased methylation of GLRX2 promoter CTD PMID:23740543 NCBI chr13:55,481,875...55,504,737
Ensembl chr13:55,482,694...55,492,831 		JBrowse link
G Gna14 G protein subunit alpha 14 decreases methylation EXP n-hexane results in decreased methylation of GNA14 promoter CTD PMID:23740543 NCBI chr 1:213,714,993...213,900,083
Ensembl chr 1:213,716,020...213,897,423 		JBrowse link
G Gnaq G protein subunit alpha q decreases methylation EXP n-hexane results in decreased methylation of GNAQ promoter CTD PMID:23740543 NCBI chr 1:213,425,631...213,671,947
Ensembl chr 1:213,424,465...213,667,672 		JBrowse link
G Gosr1 golgi SNAP receptor complex member 1 decreases methylation EXP n-hexane results in decreased methylation of GOSR1 promoter CTD PMID:23740543 NCBI chr10:61,570,499...61,607,287
Ensembl chr10:61,450,494...61,607,177
Ensembl chr10:61,450,494...61,607,177 		JBrowse link
G Grm6 glutamate metabotropic receptor 6 decreases methylation EXP n-hexane results in decreased methylation of GRM6 promoter CTD PMID:23740543 NCBI chr10:35,167,985...35,182,717
Ensembl chr10:35,167,985...35,182,717 		JBrowse link
G Gsr glutathione-disulfide reductase increases expression ISO n-hexane results in increased expression of GSR mRNA CTD PMID:20566472 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions		 ISO n-hexane results in increased expression of HMOX1 mRNA
[Particulate Matter co-treated with n-hexane] results in increased expression of HMOX1 mRNA		 CTD PMID:20566472 PMID:30503853 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hook1 hook microtubule-tethering protein 1 decreases methylation EXP n-hexane results in decreased methylation of HOOK1 promoter CTD PMID:23740543 NCBI chr 5:110,824,501...110,887,791
Ensembl chr 5:110,824,501...110,887,787 		JBrowse link
G Hp1bp3 heterochromatin protein 1, binding protein 3 decreases methylation EXP n-hexane results in decreased methylation of HP1BP3 promoter CTD PMID:23740543 NCBI chr 5:150,435,781...150,463,004
Ensembl chr 5:150,433,740...150,463,000 		JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO [Particulate Matter co-treated with n-hexane] results in increased expression of IL1A mRNA; carazolol promotes the reaction [[Particulate Matter co-treated with n-hexane] results in increased expression of IL1A mRNA] CTD PMID:30503853 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO [Particulate Matter co-treated with n-hexane] results in increased expression of IL1B mRNA CTD PMID:30503853 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 increases expression ISO n-hexane results in increased expression of IL6 protein CTD PMID:23353815 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Ing2 inhibitor of growth family, member 2 decreases methylation EXP n-hexane results in decreased methylation of ING2 promoter CTD PMID:23740543 NCBI chr16:44,573,592...44,584,180
Ensembl chr16:44,575,597...44,583,482 		JBrowse link
G Kcnk1 potassium two pore domain channel subfamily K member 1 increases methylation EXP n-hexane results in increased methylation of KCNK1 promoter CTD PMID:23740543 NCBI chr19:53,959,411...53,997,726
Ensembl chr19:53,959,657...53,997,724 		JBrowse link
G Khdrbs1 KH RNA binding domain containing, signal transduction associated 1 decreases methylation EXP n-hexane results in decreased methylation of KHDRBS1 promoter CTD PMID:23740543 NCBI chr 5:142,051,844...142,089,175
Ensembl chr 5:142,063,570...142,089,180 		JBrowse link
G Kif15 kinesin family member 15 increases methylation EXP n-hexane results in increased methylation of KIF15 promoter CTD PMID:23740543 NCBI chr 8:122,601,888...122,672,750
Ensembl chr 8:122,601,897...122,672,750 		JBrowse link
G Klhl21 kelch-like family member 21 decreases methylation EXP n-hexane results in decreased methylation of KLHL21 promoter CTD PMID:23740543 NCBI chr 5:162,514,888...162,523,545
Ensembl chr 5:162,514,765...162,523,545 		JBrowse link
G Krt84 keratin 84 decreases methylation EXP n-hexane results in decreased methylation of KRT84 promoter CTD PMID:23740543 NCBI chr 7:132,649,064...132,656,885
Ensembl chr 7:132,649,061...132,656,874 		JBrowse link
G Letm2 leucine zipper and EF-hand containing transmembrane protein 2 decreases methylation EXP n-hexane results in decreased methylation of LETM2 promoter CTD PMID:23740543 NCBI chr16:66,464,958...66,489,640
Ensembl chr16:66,469,111...66,489,704 		JBrowse link
G Loxl4 lysyl oxidase-like 4 increases methylation EXP n-hexane results in increased methylation of LOXL4 promoter CTD PMID:23740543 NCBI chr 1:241,396,183...241,416,385
Ensembl chr 1:241,397,983...241,416,322 		JBrowse link
G Lrfn1 leucine rich repeat and fibronectin type III domain containing 1 increases methylation EXP n-hexane results in increased methylation of LRFN1 promoter CTD PMID:23740543 NCBI chr 1:83,742,442...83,761,450
Ensembl chr 1:83,682,964...83,761,449 		JBrowse link
G Lrfn3 leucine rich repeat and fibronectin type III domain containing 3 decreases methylation EXP n-hexane results in decreased methylation of LRFN3 promoter CTD PMID:23740543 NCBI chr 1:85,616,862...85,623,725
Ensembl chr 1:85,616,868...85,623,725 		JBrowse link
G Mafg MAF bZIP transcription factor G increases expression ISO n-hexane results in increased expression of MAFG mRNA CTD PMID:20566472 NCBI chr10:105,903,307...105,911,808
Ensembl chr10:105,903,237...105,912,026 		JBrowse link
G Magi2 membrane associated guanylate kinase, WW and PDZ domain containing 2 increases methylation EXP n-hexane results in increased methylation of MAGI2 promoter CTD PMID:23740543 NCBI chr 4:14,386,389...15,870,036
Ensembl chr 4:14,386,399...15,870,240 		JBrowse link
G Marchf8 membrane associated ring-CH-type finger 8 decreases methylation EXP n-hexane results in decreased methylation of MARCHF8 promoter CTD PMID:23740543 NCBI chr 4:149,415,642...149,530,771
Ensembl chr 4:149,416,071...149,530,770 		JBrowse link
G Mau2 MAU2 sister chromatid cohesion factor decreases methylation EXP n-hexane results in decreased methylation of MAU2 promoter CTD PMID:23740543 NCBI chr16:19,383,847...19,414,996
Ensembl chr16:19,383,492...19,408,727 		JBrowse link
G Mdk midkine decreases methylation EXP n-hexane results in decreased methylation of MDK promoter CTD PMID:23740543 NCBI chr 3:77,901,134...77,903,997
Ensembl chr 3:77,901,158...77,903,130 		JBrowse link
G Me1 malic enzyme 1 increases expression ISO n-hexane results in increased expression of ME1 mRNA CTD PMID:20566472 NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304 		JBrowse link
G Mei1 meiotic double-stranded break formation protein 1 decreases methylation EXP n-hexane results in decreased methylation of MEI1 promoter CTD PMID:23740543 NCBI chr 7:113,590,142...113,643,513
Ensembl chr 7:113,590,142...113,643,511 		JBrowse link
G Mfap2 microfibril associated protein 2 decreases methylation EXP n-hexane results in decreased methylation of MFAP2 promoter CTD PMID:23740543 NCBI chr 5:153,312,068...153,320,266
Ensembl chr 5:153,314,711...153,320,259 		JBrowse link
G Mip major intrinsic protein of lens fiber increases methylation EXP n-hexane results in increased methylation of MIP promoter CTD PMID:23740543 NCBI chr 7:643,502...653,121
Ensembl chr 7:647,315...654,400 		JBrowse link
G Mpped2 metallophosphoesterase domain containing 2 decreases methylation EXP n-hexane results in decreased methylation of MPPED2 promoter CTD PMID:23740543 NCBI chr 3:93,180,895...93,355,605
Ensembl chr 3:93,181,167...93,355,618 		JBrowse link
G Ndufb4 NADH:ubiquinone oxidoreductase subunit B4 decreases methylation EXP n-hexane results in decreased methylation of NDUFB4 promoter CTD PMID:23740543 NCBI chr11:63,063,723...63,070,426
Ensembl chr11:63,063,795...63,070,425 		JBrowse link
G Ndufb8 NADH:ubiquinone oxidoreductase subunit B8 decreases methylation EXP n-hexane results in decreased methylation of NDUFB8 promoter CTD PMID:23740543 NCBI chr 1:243,408,656...243,413,715
Ensembl chr 1:243,408,619...243,413,817 		JBrowse link
G Nfatc2ip nuclear factor of activated T-cells 2 interacting protein increases methylation EXP n-hexane results in increased methylation of NFATC2IP promoter CTD PMID:23740543 NCBI chr 1:180,954,834...180,971,847
Ensembl chr 1:180,955,043...180,971,747 		JBrowse link
G Npepl1 aminopeptidase-like 1 increases methylation EXP n-hexane results in increased methylation of NPEPL1 promoter CTD PMID:23740543 NCBI chr 3:162,893,932...162,906,491
Ensembl chr 3:162,893,943...162,906,492 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO n-hexane results in increased expression of NQO1 mRNA CTD PMID:20566472 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Odc1 ornithine decarboxylase 1 decreases methylation EXP n-hexane results in decreased methylation of ODC1 promoter CTD PMID:23740543 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440 		JBrowse link
G Pcid2 PCI domain containing 2 decreases methylation EXP n-hexane results in decreased methylation of PCID2 promoter CTD PMID:23740543 NCBI chr16:76,423,245...76,448,712
Ensembl chr16:76,423,245...76,448,712 		JBrowse link
G Pgd phosphogluconate dehydrogenase increases expression ISO n-hexane results in increased expression of PGD mRNA CTD PMID:20566472 NCBI chr 5:159,582,746...159,598,945
Ensembl chr 5:159,561,271...159,742,778 		JBrowse link
G Phlda1 pleckstrin homology-like domain, family A, member 1 decreases methylation EXP n-hexane results in decreased methylation of PHLDA1 promoter CTD PMID:23740543 NCBI chr 7:46,967,433...46,969,637
Ensembl chr 7:46,967,409...46,969,861 		JBrowse link
G Poglut3 protein O-glucosyltransferase 3 decreases methylation EXP n-hexane results in decreased methylation of POGLUT3 promoter CTD PMID:23740543 NCBI chr 8:53,777,614...53,795,404
Ensembl chr 8:53,777,785...53,795,399 		JBrowse link
G Ppp1cb protein phosphatase 1 catalytic subunit beta decreases methylation EXP n-hexane results in decreased methylation of PPP1CB promoter CTD PMID:23740543 NCBI chr 6:23,958,813...23,992,841
Ensembl chr 6:23,960,998...23,992,824 		JBrowse link
G Prok2 prokineticin 2 decreases methylation EXP n-hexane results in decreased methylation of PROK2 promoter CTD PMID:23740543 NCBI chr 4:132,346,681...132,361,754
Ensembl chr 4:132,347,103...132,361,385 		JBrowse link
G Prpf19 pre-mRNA processing factor 19 decreases methylation EXP n-hexane results in decreased methylation of PRPF19 promoter CTD PMID:23740543 NCBI chr 1:207,541,582...207,552,664
Ensembl chr 1:207,541,595...207,552,662 		JBrowse link
G Prps2 phosphoribosyl pyrophosphate synthetase 2 decreases methylation EXP n-hexane results in decreased methylation of PRPS2 promoter CTD PMID:23740543 NCBI chr  X:26,975,915...27,013,184
Ensembl chr  X:26,976,061...27,013,181 		JBrowse link
G Ptgr1 prostaglandin reductase 1 increases expression ISO n-hexane results in increased expression of PTGR1 mRNA CTD PMID:20566472 NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO [Particulate Matter co-treated with n-hexane] results in increased expression of PTGS2 mRNA CTD PMID:30503853 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Rab5b RAB5B, member RAS oncogene family decreases methylation EXP n-hexane results in decreased methylation of RAB5B promoter CTD PMID:23740543 NCBI chr 7:1,109,449...1,128,348
Ensembl chr 7:1,109,454...1,128,268 		JBrowse link
G Rabl6 RAB, member RAS oncogene family-like 6 decreases methylation EXP n-hexane results in decreased methylation of RABL6 promoter CTD PMID:23740543 NCBI chr 3:8,402,666...8,428,588
Ensembl chr 3:8,402,672...8,428,611 		JBrowse link
G Raly RALY heterogeneous nuclear ribonucleoprotein decreases methylation EXP n-hexane results in decreased methylation of RALY promoter CTD PMID:23740543 NCBI chr 3:143,306,039...143,370,542
Ensembl chr 3:143,306,300...143,370,539 		JBrowse link
G Reep1 receptor accessory protein 1 decreases methylation EXP n-hexane results in decreased methylation of REEP1 promoter CTD PMID:23740543 NCBI chr 4:103,746,004...103,862,347
Ensembl chr 4:103,745,633...103,862,338 		JBrowse link
G RGD1311745 similar to RIKEN cDNA 1110059G10 increases methylation EXP n-hexane results in increased methylation of RGD1311745 promoter CTD PMID:23740543 NCBI chr 8:122,598,363...122,609,127
Ensembl chr 8:122,598,401...122,609,168 		JBrowse link
G Rp2 RP2 activator of ARL3 GTPase decreases methylation EXP n-hexane results in decreased methylation of RP2 promoter CTD PMID:23740543 NCBI chr  X:1,872,582...1,916,704
Ensembl chr  X:1,873,306...1,916,688 		JBrowse link
G Rprm reprimo, TP53 dependent G2 arrest mediator homolog increases methylation EXP n-hexane results in increased methylation of RPRM promoter CTD PMID:23740543 NCBI chr 3:38,539,581...38,540,998
Ensembl chr 3:38,539,581...38,540,998 		JBrowse link
G Rps6ka5 ribosomal protein S6 kinase A5 decreases methylation EXP n-hexane results in decreased methylation of RPS6KA5 promoter CTD PMID:23740543 NCBI chr 6:119,828,823...120,006,190
Ensembl chr 6:119,828,846...120,006,224 		JBrowse link
G Saxo5 stabilizer of axonemal microtubules 5 decreases methylation EXP n-hexane results in decreased methylation of SAXO5 promoter CTD PMID:23740543 NCBI chr12:1,520,983...1,538,127
Ensembl chr12:1,521,014...1,538,118 		JBrowse link
G Selenov selenoprotein V decreases methylation EXP n-hexane results in decreased methylation of SELENOV promoter CTD PMID:23740543 NCBI chr 1:83,551,473...83,558,756
Ensembl chr 1:83,551,473...83,558,756 		JBrowse link
G Sema5b semaphorin 5B decreases methylation EXP n-hexane results in decreased methylation of SEMA5B promoter CTD PMID:23740543 NCBI chr11:65,102,532...65,225,456
Ensembl chr11:65,102,031...65,225,311 		JBrowse link
G Serpinb2 serpin family B member 2 multiple interactions ISO [Particulate Matter co-treated with n-hexane] results in increased expression of SERPINB2 mRNA CTD PMID:30503853 NCBI chr13:23,537,312...23,551,823
Ensembl chr13:23,541,400...23,550,408 		JBrowse link
G Sidt2 SID1 transmembrane family, member 2 decreases methylation EXP n-hexane results in decreased methylation of SIDT2 promoter CTD PMID:23740543 NCBI chr 8:46,232,379...46,248,913
Ensembl chr 8:46,232,383...46,248,700 		JBrowse link
G Sipa1l3 signal-induced proliferation-associated 1 like 3 decreases methylation EXP n-hexane results in decreased methylation of SIPA1L3 promoter CTD PMID:23740543 NCBI chr 1:84,618,714...84,825,956
Ensembl chr 1:84,618,719...84,703,802 		JBrowse link
G Slc27a3 solute carrier family 27 member 3 decreases methylation EXP n-hexane results in decreased methylation of SLC27A3 promoter CTD PMID:23740543 NCBI chr 2:175,853,241...175,857,909
Ensembl chr 2:175,853,241...175,857,909 		JBrowse link
G Slc39a14 solute carrier family 39 member 14 increases expression ISO n-hexane results in increased expression of SLC39A14 mRNA CTD PMID:23353815 NCBI chr15:45,376,806...45,423,549
Ensembl chr15:45,376,917...45,423,524 		JBrowse link
G Slc40a1 solute carrier family 40 member 1 decreases expression ISO n-hexane results in decreased expression of SLC40A1 mRNA CTD PMID:23353815 NCBI chr 9:48,033,526...48,053,876
Ensembl chr 9:48,033,526...48,051,481 		JBrowse link
G Slc47a1 solute carrier family 47 member 1 decreases methylation EXP n-hexane results in decreased methylation of SLC47A1 promoter CTD PMID:23740543 NCBI chr10:46,034,115...46,088,617
Ensembl chr10:46,034,122...46,087,637 		JBrowse link
G Slc52a3 solute carrier family 52 member 3 decreases methylation EXP n-hexane results in decreased methylation of SLC52A3 promoter CTD PMID:23740543 NCBI chr 3:140,498,924...140,515,845
Ensembl chr 3:140,509,473...140,514,096 		JBrowse link
G Slc7a5 solute carrier family 7 member 5 decreases methylation EXP n-hexane results in decreased methylation of SLC7A5 promoter CTD PMID:23740543 NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823 		JBrowse link
G Slco4c1 solute carrier organic anion transporter family, member 4C1 decreases methylation EXP n-hexane results in decreased methylation of SLCO4C1 promoter CTD PMID:23740543 NCBI chr 9:97,177,497...97,229,161
Ensembl chr 9:97,178,861...97,229,715 		JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO n-hexane results in increased expression of SRXN1 mRNA CTD PMID:20566472 NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448 		JBrowse link
G Star steroidogenic acute regulatory protein affects expression
affects methylation		 EXP n-hexane affects the expression of STAR mRNA; n-hexane affects the expression of STAR protein
n-hexane affects the methylation of STAR promoter		 CTD PMID:26410608 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672 		JBrowse link
G Sugp1 SURP and G patch domain containing 1 decreases methylation EXP n-hexane results in decreased methylation of SUGP1 promoter CTD PMID:23740543 NCBI chr16:19,352,659...19,383,533
Ensembl chr16:19,351,793...19,383,756 		JBrowse link
G Syngr1 synaptogyrin 1 decreases methylation EXP n-hexane results in decreased methylation of SYNGR1 promoter CTD PMID:23740543 NCBI chr 7:111,635,911...111,659,341
Ensembl chr 7:111,635,918...111,659,341 		JBrowse link
G Tacstd2 tumor-associated calcium signal transducer 2 increases methylation EXP n-hexane results in increased methylation of TACSTD2 promoter CTD PMID:23740543 NCBI chr 4:96,707,950...96,709,650
Ensembl chr 4:96,707,951...96,709,650 		JBrowse link
G Tbcb tubulin folding cofactor B increases methylation EXP n-hexane results in increased methylation of TBCB promoter CTD PMID:23740543 NCBI chr 1:85,477,639...85,483,488
Ensembl chr 1:85,477,640...85,483,488 		JBrowse link
G Tmem14c transmembrane protein 14C decreases methylation EXP n-hexane results in decreased methylation of TMEM14C promoter CTD PMID:23740543 NCBI chr17:23,733,769...23,739,906
Ensembl chr17:23,733,894...23,753,320 		JBrowse link
G Tspyl4 TSPY-like 4 decreases methylation EXP n-hexane results in decreased methylation of TSPYL4 promoter CTD PMID:23740543 NCBI chr20:38,098,756...38,100,752
Ensembl chr20:38,098,677...38,103,053 		JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO n-hexane results in increased expression of TXNRD1 mRNA CTD PMID:20566472 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863 		JBrowse link
G Usp11 ubiquitin specific peptidase 11 increases methylation EXP n-hexane results in increased methylation of USP11 promoter CTD PMID:23740543 NCBI chr  X:1,473,349...1,489,520
Ensembl chr  X:1,473,350...1,489,520 		JBrowse link
G Vegfc vascular endothelial growth factor C decreases methylation EXP n-hexane results in decreased methylation of VEGFC promoter CTD PMID:23740543 NCBI chr16:37,712,251...37,827,845
Ensembl chr16:37,712,262...37,827,848 		JBrowse link
G Vim vimentin multiple interactions ISO n-hexane metabolite promotes the reaction [VIM protein binds to VIM protein] CTD PMID:6361548 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187 		JBrowse link
G Vstm4 V-set and transmembrane domain containing 4 decreases methylation EXP n-hexane results in decreased methylation of VSTM4 promoter CTD PMID:23740543 NCBI chr16:8,120,336...8,200,272
Ensembl chr16:8,120,336...8,200,269 		JBrowse link
G Wwp1 WW domain containing E3 ubiquitin protein ligase 1 decreases methylation EXP n-hexane results in decreased methylation of WWP1 promoter CTD PMID:23740543 NCBI chr 5:33,092,379...33,185,887
Ensembl chr 5:33,098,494...33,186,046 		JBrowse link
G Zfp593 zinc finger protein 593 increases methylation EXP n-hexane results in increased methylation of ZFP593 promoter CTD PMID:23740543 NCBI chr 5:146,462,670...146,464,998
Ensembl chr 5:146,462,670...146,465,198 		JBrowse link
G Zpr1 ZPR1 zinc finger decreases methylation EXP n-hexane results in decreased methylation of ZPR1 promoter CTD PMID:23740543 NCBI chr 8:46,564,898...46,574,719
Ensembl chr 8:46,565,146...46,574,719 		JBrowse link
2,5-hexanedione term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abi2 abl-interactor 2 increases expression EXP 2,5-hexanedione results in increased expression of ABI2 mRNA CTD PMID:22952946 PMID:27466211 NCBI chr 9:61,827,186...61,905,703
Ensembl chr 9:61,827,139...61,905,699 		JBrowse link
G Aco2 aconitase 2 increases expression EXP 2,5-hexanedione results in increased expression of ACO2 protein CTD PMID:19033394 NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261 		JBrowse link
G Aif1 allograft inflammatory factor 1 increases expression
multiple interactions		 EXP 2,5-hexanedione results in increased expression of AIF1 protein
Glyburide inhibits the reaction [2,5-hexanedione results in increased expression of AIF1 protein]		 CTD PMID:32522579 PMID:32860822 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation
increases expression		 ISO 2,5-hexanedione results in decreased phosphorylation of AKT1 protein
2,5-hexanedione results in increased expression of AKT1 mRNA		 CTD PMID:33197454 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Alox15b arachidonate 15-lipoxygenase, type B decreases expression EXP 2,5-hexanedione results in decreased expression of ALOX15B mRNA CTD PMID:22952946 NCBI chr10:53,892,496...53,901,812
Ensembl chr10:53,892,466...53,901,812 		JBrowse link
G Angptl4 angiopoietin-like 4 affects expression EXP 2,5-hexanedione affects the expression of ANGPTL4 mRNA CTD PMID:20616210 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519 		JBrowse link
G Arg1 arginase 1 decreases expression
multiple interactions		 EXP 2,5-hexanedione results in decreased expression of ARG1 mRNA
Glyburide inhibits the reaction [2,5-hexanedione results in decreased expression of ARG1 mRNA]		 CTD PMID:32522579 PMID:32860822 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO
EXP		 2,5-hexanedione results in increased expression of BAX mRNA; 2,5-hexanedione results in increased expression of BAX protein CTD PMID:17492505 PMID:21901545 PMID:22337490 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression
decreases expression		 EXP
ISO		 2,5-hexanedione results in increased expression of BCL2 protein
2,5-hexanedione results in decreased expression of BCL2 mRNA
2,5-hexanedione results in decreased expression of BCL2 mRNA; 2,5-hexanedione results in decreased expression of BCL2 protein		 CTD PMID:17492505 PMID:21901545 PMID:22337490 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l14 Bcl2-like 14 increases expression EXP 2,5-hexanedione results in increased expression of BCL2L14 mRNA CTD PMID:22952946 NCBI chr 4:167,217,561...167,258,723
Ensembl chr 4:167,219,871...167,258,086 		JBrowse link
G Bdnf brain-derived neurotrophic factor decreases expression EXP 2,5-hexanedione results in decreased expression of BDNF protein CTD PMID:31760062 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Bfar bifunctional apoptosis regulator increases expression EXP 2,5-hexanedione results in increased expression of BFAR mRNA CTD PMID:22952946 NCBI chr10:1,552,019...1,585,040
Ensembl chr10:1,552,072...1,585,038 		JBrowse link
G Casp1 caspase 1 increases cleavage
increases expression
multiple interactions		 EXP 2,5-hexanedione results in increased cleavage of CASP1 protein
2,5-hexanedione results in increased expression of CASP1 mRNA
Glyburide inhibits the reaction [2,5-hexanedione results in increased cleavage of CASP1 protein]		 CTD PMID:32522579 PMID:32860822 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Casp3 caspase 3 increases expression ISO
EXP		 2,5-hexanedione results in increased expression of CASP3 mRNA; 2,5-hexanedione results in increased expression of CASP3 protein alternative form CTD PMID:17492505 PMID:21901545 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp8 caspase 8 decreases expression ISO 2,5-hexanedione results in decreased expression of CASP8 protein CTD PMID:33197454 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Ccdc171 coiled-coil domain containing 171 increases expression EXP 2,5-hexanedione results in increased expression of CCDC171 mRNA CTD PMID:22952946 NCBI chr 5:97,919,965...98,403,853
Ensembl chr 5:97,920,002...98,282,833 		JBrowse link
G Ccdc191 coiled-coil domain containing 191 increases expression EXP 2,5-hexanedione results in increased expression of CCDC191 mRNA CTD PMID:22952946 NCBI chr11:56,735,655...56,806,372
Ensembl chr11:56,735,652...56,806,375 		JBrowse link
G Cdin1 CDAN1 interacting nuclease 1 increases expression EXP 2,5-hexanedione results in increased expression of CDIN1 mRNA CTD PMID:22952946 NCBI chr 3:102,441,553...102,646,935
Ensembl chr 3:102,441,704...102,646,682 		JBrowse link
G Cep112 centrosomal protein 112 increases expression EXP 2,5-hexanedione results in increased expression of CEP112 mRNA CTD PMID:22952946 NCBI chr10:93,366,059...93,833,133
Ensembl chr10:93,366,136...93,833,131 		JBrowse link
G Cfap221 cilia and flagella associated protein 221 increases expression EXP 2,5-hexanedione results in increased expression of CFAP221 mRNA CTD PMID:22952946 NCBI chr13:31,046,550...31,118,141
Ensembl chr13:31,046,535...31,116,899 		JBrowse link
G Ckmt1 creatine kinase, mitochondrial 1 increases expression EXP 2,5-hexanedione results in increased expression of CKMT1B protein CTD PMID:19033394 NCBI chr 3:108,329,859...108,335,760
Ensembl chr 3:108,330,705...108,335,758 		JBrowse link
G Clca2 chloride channel accessory 2 multiple interactions EXP [carbendazim co-treated with 2,5-hexanedione] results in decreased expression of CLCA2 mRNA CTD PMID:22382377 NCBI chr 2:233,993,619...234,022,691
Ensembl chr 2:233,995,078...234,022,199 		JBrowse link
G Clu clusterin decreases expression
increases expression		 EXP 2,5-hexanedione results in decreased expression of CLU mRNA
2,5-hexanedione results in increased expression of CLU mRNA		 CTD PMID:22952946 PMID:27466211 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315 		JBrowse link
G Ctxn1 cortexin 1 increases expression EXP 2,5-hexanedione results in increased expression of CTXN1 mRNA CTD PMID:22952946 NCBI chr12:2,610,465...2,612,076 JBrowse link
G Dcn decorin increases expression EXP 2,5-hexanedione results in increased expression of DCN mRNA CTD PMID:22952946 NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270 		JBrowse link
G Dennd1a DENN domain containing 1A increases expression EXP 2,5-hexanedione results in increased expression of DENND1A mRNA CTD PMID:22952946 NCBI chr 3:21,564,749...22,052,057
Ensembl chr 3:21,564,749...22,052,062 		JBrowse link
G Dicer1 dicer 1 ribonuclease III increases expression ISO 2,5-hexanedione results in increased expression of DICER1 mRNA CTD PMID:33197454 NCBI chr 6:123,627,529...123,692,278
Ensembl chr 6:123,631,250...123,693,965 		JBrowse link
G Dnaaf11 dynein axonemal assembly factor 11 increases expression EXP 2,5-hexanedione results in increased expression of DNAAF11 mRNA CTD PMID:22952946 NCBI chr 7:98,141,525...98,245,906
Ensembl chr 7:98,144,763...98,245,837 		JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 increases expression EXP 2,5-hexanedione results in increased expression of DNAJB4 mRNA CTD PMID:22952946 NCBI chr 2:241,129,346...241,159,272
Ensembl chr 2:241,130,340...241,159,089 		JBrowse link
G Dpp7 dipeptidylpeptidase 7 multiple interactions EXP [carbendazim co-treated with 2,5-hexanedione] results in decreased expression of DPP7 mRNA CTD PMID:22382377 NCBI chr 3:8,165,091...8,169,343
Ensembl chr 3:8,165,091...8,169,355 		JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 decreases expression EXP 2,5-hexanedione results in decreased expression of DPYSL2 protein CTD PMID:19033394 NCBI chr15:41,005,551...41,111,724
Ensembl chr15:41,005,551...41,111,829 		JBrowse link
G Egfr epidermal growth factor receptor increases expression EXP 2,5-hexanedione results in increased expression of EGFR mRNA CTD PMID:16141653 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Erc1 ELKS/RAB6-interacting/CAST family member 1 increases expression EXP 2,5-hexanedione results in increased expression of ERC1 mRNA CTD PMID:22952946 NCBI chr 4:152,763,664...153,055,724
Ensembl chr 4:152,767,419...153,055,639 		JBrowse link
G Faslg Fas ligand increases expression EXP 2,5-hexanedione results in increased expression of FASLG mRNA CTD PMID:22337490 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Fasn fatty acid synthase decreases expression EXP 2,5-hexanedione results in decreased expression of FASN protein CTD PMID:19033394 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261 		JBrowse link
G Fcer1g Fc epsilon receptor Ig increases expression EXP 2,5-hexanedione results in increased expression of FCER1G mRNA CTD PMID:22952946 NCBI chr13:83,649,447...83,654,248
Ensembl chr13:83,649,449...83,671,443 		JBrowse link
G Foxo3 forkhead box O3 increases phosphorylation
decreases expression		 ISO 2,5-hexanedione results in increased phosphorylation of FOXO3 protein
2,5-hexanedione results in decreased expression of FOXO3 mRNA		 CTD PMID:33197454 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression EXP 2,5-hexanedione results in increased expression of GADD45 mRNA CTD PMID:16141653 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G Gas2 growth arrest-specific 2 increases expression EXP 2,5-hexanedione results in increased expression of GAS2 mRNA CTD PMID:22952946 NCBI chr 1:101,452,361...101,582,619
Ensembl chr 1:101,482,591...101,582,619 		JBrowse link
G Gfap glial fibrillary acidic protein decreases expression
increases expression		 EXP 2,5-hexanedione results in decreased expression of GFAP protein
2,5-hexanedione results in increased expression of GFAP protein		 CTD PMID:19033394 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589 		JBrowse link
G Ghsr growth hormone secretagogue receptor affects expression EXP 2,5-hexanedione affects the expression of GHSR mRNA CTD PMID:20616210 NCBI chr 2:110,268,489...110,271,865
Ensembl chr 2:110,268,489...110,271,865 		JBrowse link
G Glud1 glutamate dehydrogenase 1 increases expression EXP 2,5-hexanedione results in increased expression of GLUD1 protein CTD PMID:19033394 NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957 		JBrowse link
G Gsdmd gasdermin D multiple interactions
increases cleavage		 EXP Glyburide inhibits the reaction [2,5-hexanedione results in increased cleavage of GSDMD protein] CTD PMID:32522579 PMID:32860822 NCBI chr 7:107,542,489...107,547,051
Ensembl chr 7:107,542,083...107,547,055 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases expression EXP 2,5-hexanedione results in decreased expression of GSK3B protein CTD PMID:31760062 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Gsn gelsolin decreases expression EXP 2,5-hexanedione results in decreased expression of GSN protein CTD PMID:19033394 NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402 		JBrowse link
G Gstm5l glutathione S-transferase, mu 5-like decreases expression EXP 2,5-hexanedione results in decreased expression of GSTM5 protein CTD PMID:19033394 NCBI chr 2:195,544,424...195,549,895
Ensembl chr 2:195,544,426...195,628,961 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 decreases expression EXP 2,5-hexanedione results in decreased expression of GSTP1 mRNA CTD PMID:16141653 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Hdgfl1 HDGF like 1 decreases expression EXP 2,5-hexanedione results in decreased expression of HDGFL1 mRNA CTD PMID:22952946 NCBI chr17:38,207,906...38,209,902 JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B increases expression EXP 2,5-hexanedione results in increased expression of HSPA1B mRNA CTD PMID:16141653 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240 		JBrowse link
G Ier3 immediate early response 3 affects expression EXP 2,5-hexanedione affects the expression of IER3 mRNA CTD PMID:20616210 NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583 		JBrowse link
G Ift81 intraflagellar transport 81 increases expression EXP 2,5-hexanedione results in increased expression of IFT81 mRNA CTD PMID:22952946 NCBI chr12:33,957,744...34,037,164
Ensembl chr12:33,957,806...34,037,057 		JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 decreases expression EXP 2,5-hexanedione results in decreased expression of IGFBP3 mRNA CTD PMID:16141653 NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083 		JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions		 EXP 2,5-hexanedione results in increased expression of IL1B mRNA; 2,5-hexanedione results in increased expression of IL1B protein
Glyburide inhibits the reaction [2,5-hexanedione results in increased expression of IL1B protein]		 CTD PMID:16141653 PMID:32522579 PMID:32860822 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Ina internexin neuronal intermediate filament protein, alpha decreases expression EXP 2,5-hexanedione results in decreased expression of INA protein CTD PMID:19033394 NCBI chr 1:245,896,775...245,908,330
Ensembl chr 1:245,896,775...245,908,330 		JBrowse link
G Itgam integrin subunit alpha M increases expression
multiple interactions		 ISO
EXP		 2,5-hexanedione results in increased expression of ITGAM protein
Glyburide inhibits the reaction [2,5-hexanedione results in increased expression of ITGAM protein]		 CTD PMID:19464574 PMID:32522579 PMID:32860822 NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503 		JBrowse link
G Itgb1 integrin subunit beta 1 decreases expression EXP 2,5-hexanedione results in decreased expression of ITGB1 mRNA CTD PMID:16141653 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195 		JBrowse link
G Kiaa0930 KIAA0930 homolog increases expression EXP 2,5-hexanedione results in increased expression of KIAA0930 mRNA CTD PMID:22952946 NCBI chr 7:116,067,974...116,107,678
Ensembl chr 7:116,071,447...116,107,727 		JBrowse link
G Kiaa1328 KIAA1328 homolog increases expression EXP 2,5-hexanedione results in increased expression of KIAA1328 mRNA CTD PMID:22952946 NCBI chr18:16,488,569...16,776,373
Ensembl chr18:16,489,408...16,775,548 		JBrowse link
G Kif6 kinesin family member 6 increases expression EXP 2,5-hexanedione results in increased expression of KIF6 mRNA CTD PMID:22952946 NCBI chr 9:11,076,203...11,373,205
Ensembl chr 9:11,072,824...11,373,006 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase decreases expression
multiple interactions		 EXP 2,5-hexanedione results in decreased expression of KIT protein
resveratrol inhibits the reaction [2,5-hexanedione results in decreased expression of KIT protein]		 CTD PMID:17725299 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652 		JBrowse link
G Loxl1 lysyl oxidase-like 1 increases expression
multiple interactions		 EXP 2,5-hexanedione results in increased expression of LOXL1 protein
2,5-hexanedione promotes the reaction [carbendazim results in increased expression of LOXL1 protein]; [carbendazim co-treated with 2,5-hexanedione] results in decreased expression of LOXL1 mRNA		 CTD PMID:22382377 NCBI chr 8:58,691,763...58,716,365
Ensembl chr 8:58,692,593...58,716,356 		JBrowse link
G Lrrc69 leucine rich repeat containing 69 increases expression EXP 2,5-hexanedione results in increased expression of LRRC69 mRNA CTD PMID:22952946 NCBI chr 5:28,023,591...28,181,963
Ensembl chr 5:28,023,593...28,214,384 		JBrowse link
G Lyz2 lysozyme 2 decreases expression
increases expression		 EXP 2,5-hexanedione results in decreased expression of LYZ2 mRNA
2,5-hexanedione results in increased expression of LYZ2 mRNA		 CTD PMID:22952946 NCBI chr 7:52,906,810...52,912,154
Ensembl chr 7:52,906,811...52,912,106 		JBrowse link
G Macrod1 mono-ADP ribosylhydrolase 1 increases expression
multiple interactions		 EXP 2,5-hexanedione results in increased expression of MACROD1 mRNA
[carbendazim co-treated with 2,5-hexanedione] results in decreased expression of MACROD1 mRNA		 CTD PMID:22382377 NCBI chr 1:204,246,238...204,387,027
Ensembl chr 1:204,246,166...204,389,716 		JBrowse link
G Map1a microtubule-associated protein 1A decreases expression EXP 2,5-hexanedione results in decreased expression of MAP1A protein CTD PMID:20554699 NCBI chr 3:108,263,217...108,283,936
Ensembl chr 3:108,263,151...108,282,899 		JBrowse link
G Map1b microtubule-associated protein 1B decreases expression EXP 2,5-hexanedione results in decreased expression of MAP1B protein; 2,5-hexanedione results in decreased expression of MAP1B protein modified form CTD PMID:20554699 PMID:31760062 NCBI chr 2:30,817,261...30,910,458
Ensembl chr 2:30,817,261...30,910,317 		JBrowse link
G Map2 microtubule-associated protein 2 decreases expression EXP 2,5-hexanedione results in decreased expression of MAP2 protein modified form CTD PMID:20554699 NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809 		JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 increases expression EXP 2,5-hexanedione results in increased expression of MAP3K1 protein CTD PMID:31760062 NCBI chr 2:43,348,572...43,414,706
Ensembl chr 2:43,350,098...43,414,463 		JBrowse link
G Mapt microtubule-associated protein tau decreases expression EXP 2,5-hexanedione results in decreased expression of MAPT protein modified form CTD PMID:20554699 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129 		JBrowse link
G Mbp myelin basic protein multiple interactions
decreases expression		 EXP Glyburide inhibits the reaction [2,5-hexanedione results in decreased expression of MBP protein] CTD PMID:32522579 PMID:32860822 NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404 		JBrowse link
G Mdh1 malate dehydrogenase 1 increases expression EXP 2,5-hexanedione results in increased expression of MDH1 protein CTD PMID:19033394 NCBI chr14:95,630,625...95,645,920
Ensembl chr14:95,630,306...95,645,925 		JBrowse link
G Mfap3l microfibril associated protein 3 like increases expression EXP 2,5-hexanedione results in increased expression of MFAP3L mRNA CTD PMID:22952946 NCBI chr16:29,411,643...29,454,665
Ensembl chr16:29,415,849...29,430,863 		JBrowse link
G Mir10b microRNA 10b increases expression EXP 2,5-hexanedione results in increased expression of MIR10B mRNA CTD PMID:31760062 NCBI chr 3:59,628,438...59,628,546
Ensembl chr 3:59,628,438...59,628,546 		JBrowse link
G Mir1224 microRNA 1224 increases expression EXP 2,5-hexanedione results in increased expression of MIR1224 mRNA CTD PMID:31760062 NCBI chr11:80,306,902...80,306,986
Ensembl chr11:80,306,902...80,306,986 		JBrowse link
G Mir125a microRNA 125a increases expression
decreases expression		 EXP 2,5-hexanedione results in increased expression of MIR125A mRNA
2,5-hexanedione results in decreased expression of MIR125A mRNA		 CTD PMID:31760062 NCBI chr 1:58,677,626...58,677,710
Ensembl chr 1:58,677,626...58,677,710 		JBrowse link
G Mir130b microRNA 130b decreases expression EXP 2,5-hexanedione results in decreased expression of MIR130B mRNA CTD PMID:31760062 NCBI chr11:83,880,163...83,880,244
Ensembl chr11:83,880,163...83,880,244 		JBrowse link
G Mir134 microRNA 134 decreases expression EXP 2,5-hexanedione results in decreased expression of MIR134 mRNA CTD PMID:31760062 NCBI chr 6:128,748,908...128,748,980 JBrowse link
G Mir155 microRNA 155 decreases expression EXP 2,5-hexanedione results in decreased expression of MIR155 mRNA CTD PMID:31760062 NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718 		JBrowse link
G Mir183 microRNA 183 decreases expression EXP 2,5-hexanedione results in decreased expression of MIR183 mRNA CTD PMID:31760062 NCBI chr 4:58,788,614...58,788,723
Ensembl chr 4:58,788,614...58,788,723 		JBrowse link
G Mir193 microRNA 193 increases expression EXP 2,5-hexanedione results in increased expression of MIR193 mRNA CTD PMID:31760062 NCBI chr10:64,672,354...64,672,439 JBrowse link
G Mir193a microRNA 193a decreases expression EXP 2,5-hexanedione results in decreased expression of MIR193A mRNA CTD PMID:31760062 NCBI chr10:64,672,343...64,672,454
Ensembl chr10:64,672,343...64,672,454 		JBrowse link
G Mir194-2 microRNA 194-2 decreases expression EXP 2,5-hexanedione results in decreased expression of MIR194-2 mRNA CTD PMID:31760062 NCBI chr 1:203,564,761...203,564,845
Ensembl chr 1:203,564,761...203,564,845 		JBrowse link
G Mir196a microRNA 196a increases expression EXP 2,5-hexanedione results in increased expression of MIR196A mRNA CTD PMID:31760062 NCBI chr 7:134,110,400...134,110,509
Ensembl chr 7:134,110,400...134,110,509 		JBrowse link
G Mir196c microRNA 196c increases expression EXP 2,5-hexanedione results in increased expression of MIR196C mRNA CTD PMID:31760062 NCBI chr10:81,231,006...81,231,085
Ensembl chr10:81,231,006...81,231,085 		JBrowse link
G Mir199a2 microRNA 199a-2 decreases expression EXP 2,5-hexanedione results in decreased expression of MIR199A-2 mRNA; 2,5-hexanedione results in decreased expression of MIR199A2 mRNA CTD PMID:31760062 NCBI chr13:74,582,954...74,583,063
Ensembl chr13:74,582,954...74,583,063 		JBrowse link
G Mir200c microRNA 200c decreases expression EXP 2,5-hexanedione results in decreased expression of MIR200C mRNA CTD PMID:31760062 NCBI chr 4:157,523,679...157,523,747 JBrowse link
G Mir202 microRNA 202 decreases expression EXP 2,5-hexanedione results in decreased expression of MIR202 mRNA CTD PMID:31760062 NCBI chr 1:194,754,730...194,754,801
Ensembl chr 1:194,754,730...194,754,801 		JBrowse link
G Mir206 microRNA 206 decreases expression EXP 2,5-hexanedione results in decreased expression of MIR206 mRNA CTD PMID:31760062 NCBI chr 9:23,094,249...23,094,332
Ensembl chr 9:23,094,249...23,094,332 		JBrowse link
G Mir208a microRNA 208a increases expression EXP 2,5-hexanedione results in increased expression of MIR208A mRNA CTD PMID:31760062 NCBI chr15:28,425,570...28,425,652 JBrowse link
G Mir20a microRNA 20a decreases expression EXP 2,5-hexanedione results in decreased expression of MIR20A mRNA CTD PMID:31760062 NCBI chr15:92,181,084...92,181,168
Ensembl chr15:92,181,084...92,181,168 		JBrowse link
G Mir21 microRNA 21 increases expression
decreases expression		 EXP 2,5-hexanedione results in increased expression of MIR21 mRNA
2,5-hexanedione results in decreased expression of MIR21 mRNA		 CTD PMID:31760062 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mir212 microRNA 212 increases expression EXP 2,5-hexanedione results in increased expression of MIR212 mRNA CTD PMID:31760062 NCBI chr10:60,023,403...60,023,513
Ensembl chr10:60,023,403...60,023,513 		JBrowse link
G Mir214 microRNA 214 increases expression ISO 2,5-hexanedione results in increased expression of MIR214 mRNA CTD PMID:33197454 NCBI chr13:74,588,374...74,588,481
Ensembl chr13:74,588,372...74,588,481 		JBrowse link
G Mir22 microRNA 22 increases expression EXP 2,5-hexanedione results in increased expression of MIR22 mRNA CTD PMID:31760062 NCBI chr10:60,307,039...60,307,133
Ensembl chr10:60,307,039...60,307,133 		JBrowse link
G Mir223 microRNA 223 increases expression EXP 2,5-hexanedione results in increased expression of MIR223 mRNA CTD PMID:31760062 NCBI chr  X:61,141,887...61,141,996
Ensembl chr  X:61,141,887...61,141,996 		JBrowse link
G Mir224 microRNA 224 increases expression EXP 2,5-hexanedione results in increased expression of MIR224 mRNA CTD PMID:31760062 NCBI chr  X:150,065,088...150,065,169
Ensembl chr  X:150,065,088...150,065,169 		JBrowse link
G Mir27a microRNA 27a decreases expression EXP 2,5-hexanedione results in decreased expression of MIR27A mRNA CTD PMID:31760062 NCBI chr19:23,954,831...23,954,917
Ensembl chr19:23,954,831...23,954,917 		JBrowse link
G Mir27b microRNA 27b increases expression EXP 2,5-hexanedione results in increased expression of MIR27B mRNA CTD PMID:31760062 NCBI chr17:1,813,427...1,813,523
Ensembl chr17:1,813,426...1,813,529 		JBrowse link
G Mir300 microRNA 300 increases expression EXP 2,5-hexanedione results in increased expression of MIR300 mRNA CTD PMID:31760062 NCBI chr 6:128,738,513...128,738,591
Ensembl chr 6:128,738,505...128,738,594 		JBrowse link
G Mir30a microRNA 30a increases expression EXP 2,5-hexanedione results in increased expression of MIR30A mRNA CTD PMID:31760062 NCBI chr 9:25,737,600...25,737,670
Ensembl chr 9:25,737,600...25,737,670 		JBrowse link
G Mir32 microRNA 32 increases expression EXP 2,5-hexanedione results in increased expression of MIR32 mRNA CTD PMID:31760062 NCBI chr 5:71,596,083...71,596,152
Ensembl chr 5:71,596,083...71,596,152 		JBrowse link
G Mir320a microRNA 320a increases expression EXP 2,5-hexanedione results in increased expression of MIR320A mRNA CTD PMID:31760062 NCBI chr15:45,516,392...45,516,473
Ensembl chr15:45,516,392...45,516,473 		JBrowse link
G Mir323 microRNA 323 decreases expression EXP 2,5-hexanedione results in decreased expression of MIR323 mRNA CTD PMID:31760062 NCBI chr 6:128,725,539...128,725,624
Ensembl chr 6:128,725,539...128,725,624 		JBrowse link
G Mir326 microRNA 326 increases expression EXP 2,5-hexanedione results in increased expression of MIR326 mRNA CTD PMID:31760062 NCBI chr 1:153,854,029...153,854,123
Ensembl chr 1:153,854,029...153,854,123 		JBrowse link
G Mir33 microRNA 33 increases expression EXP 2,5-hexanedione results in increased expression of MIR33 mRNA CTD PMID:31760062 NCBI chr 7:113,713,855...113,713,923
Ensembl chr 7:113,713,855...113,713,923 		JBrowse link
G Mir330 microRNA 330 increases expression EXP 2,5-hexanedione results in increased expression of MIR330 mRNA CTD PMID:31760062 NCBI chr 1:78,833,178...78,833,274
Ensembl chr 1:78,833,178...78,833,274 		JBrowse link
G Mir331 microRNA 331 decreases expression EXP 2,5-hexanedione results in decreased expression of MIR331 mRNA CTD PMID:31760062 NCBI chr 7:28,527,390...28,527,485
Ensembl chr 7:28,527,390...28,527,485 		JBrowse link
G Mir339 microRNA 339 increases expression EXP 2,5-hexanedione results in increased expression of MIR339 mRNA CTD PMID:31760062 NCBI chr12:15,277,546...15,277,641
Ensembl chr12:15,277,546...15,277,641 		JBrowse link
G Mir344-1 microRNA 344-1 decreases expression EXP 2,5-hexanedione results in decreased expression of MIR344-1 mRNA CTD PMID:31760062 NCBI chr 1:115,306,861...115,306,958 JBrowse link
G Mir345 microRNA 345 increases expression EXP 2,5-hexanedione results in increased expression of MIR345 mRNA CTD PMID:31760062 NCBI chr 6:127,754,027...127,754,122
Ensembl chr 6:127,754,027...127,754,122 		JBrowse link
G Mir3556a microRNA 3556a decreases expression EXP 2,5-hexanedione results in decreased expression of MIR3556A mRNA CTD PMID:31760062 NCBI chr 4:59,650,596...59,650,713
Ensembl chr 4:59,650,596...59,650,713 		JBrowse link
G Mir3558 microRNA 3558 decreases expression EXP 2,5-hexanedione results in decreased expression of MIR3558 mRNA CTD PMID:31760062 NCBI chr 6:7,181,751...7,181,864
Ensembl chr 6:7,181,751...7,181,864 		JBrowse link
G Mir3560 microRNA 3560 decreases expression EXP 2,5-hexanedione results in decreased expression of MIR3560 mRNA CTD PMID:31760062 NCBI chr  X:15,255,308...15,255,419
Ensembl chr  X:15,255,308...15,255,419 		JBrowse link
G Mir3573 microRNA 3573 increases expression EXP 2,5-hexanedione results in increased expression of MIR3573 mRNA CTD PMID:31760062 NCBI chr  X:64,259,096...64,259,167
Ensembl chr  X:64,259,096...64,259,167 		JBrowse link
G Mir3580 microRNA 3580 decreases expression EXP 2,5-hexanedione results in decreased expression of MIR3580 mRNA CTD PMID:31760062 NCBI chr  X:145,445,018...145,445,098
Ensembl chr  X:145,445,018...145,445,098 		JBrowse link
G Mir3593 microRNA 3593 decreases expression EXP 2,5-hexanedione results in decreased expression of MIR3593 mRNA CTD PMID:31760062 NCBI chr 6:73,252,647...73,252,737
Ensembl chr 6:73,252,647...73,252,737 		JBrowse link
G Mir370 microRNA 370 decreases expression EXP 2,5-hexanedione results in decreased expression of MIR370 mRNA CTD PMID:31760062 NCBI chr 6:128,572,257...128,572,335
Ensembl chr 6:128,572,257...128,572,335 		JBrowse link
G Mir375 microRNA 375 decreases expression EXP 2,5-hexanedione results in decreased expression of MIR375 mRNA CTD PMID:31760062 NCBI chr 9:76,457,911...76,457,985
Ensembl chr 9:76,457,911...76,457,985 		JBrowse link
G Mir412 microRNA 412 increases expression EXP 2,5-hexanedione results in increased expression of MIR412 mRNA CTD PMID:31760062 NCBI chr 6:128,757,932...128,758,001
Ensembl chr 6:128,757,926...128,758,005 		JBrowse link
G Mir423 microRNA 423 increases expression EXP 2,5-hexanedione results in increased expression of MIR423 mRNA CTD PMID:31760062 NCBI chr10:61,914,142...61,914,220
Ensembl chr10:61,914,133...61,914,226 		JBrowse link
G Mir433 microRNA 433 decreases expression EXP 2,5-hexanedione results in decreased expression of MIR433 mRNA CTD PMID:31760062 NCBI chr 6:128,545,119...128,545,211
Ensembl chr 6:128,545,112...128,545,217 		JBrowse link
G Mir450a1 microRNA 450a-1 decreases expression EXP 2,5-hexanedione results in decreased expression of MIR450A1 mRNA CTD PMID:31760062 NCBI chr  X:132,801,380...132,801,470
Ensembl chr  X:132,801,380...132,801,470 		JBrowse link
G Mir487b microRNA 487b increases expression EXP 2,5-hexanedione results in increased expression of MIR487B mRNA CTD PMID:31760062 NCBI chr 6:128,741,485...128,741,566
Ensembl chr 6:128,741,485...128,741,566 		JBrowse link
G Mir488 microRNA 488 increases expression EXP 2,5-hexanedione results in increased expression of MIR488 mRNA CTD PMID:31760062 NCBI chr13:70,683,064...70,683,142
Ensembl chr13:70,683,064...70,683,142 		JBrowse link
G Mir497 microRNA 497 decreases expression EXP 2,5-hexanedione results in decreased expression of MIR497 mRNA CTD PMID:31760062 NCBI chr10:54,951,514...54,951,582
Ensembl chr10:54,951,505...54,951,584 		JBrowse link
G Mir503 microRNA 503 decreases expression EXP 2,5-hexanedione results in decreased expression of MIR503 mRNA CTD PMID:31760062 NCBI chr  X:132,806,303...132,806,373
Ensembl chr  X:132,806,303...132,806,373 		JBrowse link
G Mir541 microRNA 541 decreases expression EXP 2,5-hexanedione results in decreased expression of MIR541 mRNA CTD PMID:31760062 NCBI chr 6:128,757,016...128,757,105
Ensembl chr 6:128,757,016...128,757,105 		JBrowse link
G Mir542 microRNA 542 increases expression EXP 2,5-hexanedione results in increased expression of MIR542 mRNA CTD PMID:31760062 NCBI chr  X:132,802,623...132,802,701
Ensembl chr  X:132,802,623...132,802,701 		JBrowse link
G Mir551b microRNA 551b decreases expression EXP 2,5-hexanedione results in decreased expression of MIR551B mRNA CTD PMID:31760062 NCBI chr 2:113,989,203...113,989,300
Ensembl chr 2:113,989,203...113,989,300 		JBrowse link
G Mir582 microRNA 582 increases expression EXP 2,5-hexanedione results in increased expression of MIR582 mRNA CTD PMID:31760062 NCBI chr 2:40,928,571...40,928,651
Ensembl chr 2:40,928,571...40,928,651 		JBrowse link
G Mir652 microRNA 652 decreases expression EXP 2,5-hexanedione results in decreased expression of MIR652 mRNA CTD PMID:31760062 NCBI chr  X:106,343,293...106,343,373
Ensembl chr  X:106,343,293...106,343,373 		JBrowse link
G Mir653 microRNA 653 decreases expression EXP 2,5-hexanedione results in decreased expression of MIR653 mRNA CTD PMID:31760062 NCBI chr 4:31,692,714...31,692,810
Ensembl chr 4:31,692,714...31,692,810 		JBrowse link
G Mir665 microRNA 665 increases expression EXP 2,5-hexanedione results in increased expression of MIR665 mRNA CTD PMID:31760062 NCBI chr 6:128,539,440...128,539,533
Ensembl chr 6:128,539,440...128,539,533 		JBrowse link
G Mir675 microRNA 675 increases expression EXP 2,5-hexanedione results in increased expression of MIR675 mRNA CTD PMID:31760062 NCBI chr 1:197,732,275...197,732,358
Ensembl chr 1:197,732,275...197,732,358 		JBrowse link
G Mir743a microRNA 743a increases expression EXP 2,5-hexanedione results in increased expression of MIR743A mRNA CTD PMID:31760062 NCBI chr  X:145,402,692...145,402,767
Ensembl chr  X:145,402,692...145,402,767 		JBrowse link
G Mir760 microRNA 760 decreases expression EXP 2,5-hexanedione results in decreased expression of MIR760 mRNA CTD PMID:31760062 NCBI chr 2:210,392,616...210,392,695
Ensembl chr 2:210,392,616...210,392,695 		JBrowse link
G Mir770 microRNA 770 increases expression EXP 2,5-hexanedione results in increased expression of MIR770 mRNA CTD PMID:31760062 NCBI chr 6:128,515,843...128,515,918
Ensembl chr 6:128,515,835...128,515,928 		JBrowse link
G Mir8 microRNA 8 increases expression EXP 2,5-hexanedione results in increased expression of MIR8 mRNA CTD PMID:31760062 NCBI chr 1:132,806,420...132,806,514
Ensembl chr 1:132,806,420...132,806,514 		JBrowse link
G Mir873 microRNA 873 increases expression EXP 2,5-hexanedione results in increased expression of MIR873 mRNA CTD PMID:31760062 NCBI chr 5:51,356,919...51,356,995
Ensembl chr 5:51,356,919...51,356,995 		JBrowse link
G Mir877 microRNA 877 increases expression EXP 2,5-hexanedione results in increased expression of MIR877 mRNA CTD PMID:31760062 NCBI chr20:2,811,476...2,811,560
Ensembl chr20:2,811,476...2,811,560 		JBrowse link
G Mir883 microRNA 883 decreases expression EXP 2,5-hexanedione results in decreased expression of MIR883 mRNA CTD PMID:31760062 NCBI chr  X:145,410,566...145,410,642
Ensembl chr  X:145,410,566...145,410,642 		JBrowse link
G Mirlet7b microRNA let-7b increases expression EXP 2,5-hexanedione results in increased expression of MIRLET7B mRNA CTD PMID:31760062 NCBI chr 7:116,804,186...116,804,270
Ensembl chr 7:116,804,186...116,804,270 		JBrowse link
G Mirlet7f-1 microRNA let7f-1 decreases expression EXP 2,5-hexanedione results in decreased expression of MIRLET7F1 mRNA CTD PMID:31760062 NCBI chr17:16,114,130...16,114,226
Ensembl chr17:16,114,130...16,114,226 		JBrowse link
G Mirlet7i microRNA let-7i increases expression EXP 2,5-hexanedione results in increased expression of MIRLET7I mRNA CTD PMID:31760062 NCBI chr 7:58,642,485...58,642,569
Ensembl chr 7:58,642,480...58,642,571 		JBrowse link
G Mrc1 mannose receptor, C type 1 decreases expression
multiple interactions		 EXP 2,5-hexanedione results in decreased expression of MRC1 mRNA
Glyburide inhibits the reaction [2,5-hexanedione results in decreased expression of MRC1 mRNA]		 CTD PMID:32522579 PMID:32860822 NCBI chr17:77,249,187...77,330,857
Ensembl chr17:77,249,187...77,330,857 		JBrowse link
G Mtm1 myotubularin 1 increases expression EXP 2,5-hexanedione results in increased expression of MTM1 mRNA CTD PMID:22952946 NCBI chr 6:488,923...506,882
Ensembl chr 6:488,969...506,860 		JBrowse link
G Napa NSF attachment protein alpha decreases expression EXP 2,5-hexanedione results in decreased expression of NAPA protein CTD PMID:19033394 NCBI chr 1:76,787,036...76,805,869
Ensembl chr 1:76,786,932...76,805,869 		JBrowse link
G Ndufa10 NADH:ubiquinone oxidoreductase subunit A10 increases expression
decreases expression		 EXP 2,5-hexanedione results in increased expression of NDUFA10 protein
2,5-hexanedione results in decreased expression of NDUFA10 protein		 CTD PMID:19033394 NCBI chr 9:93,007,034...93,041,825
Ensembl chr 9:93,007,042...93,042,560 		JBrowse link
G Nefh neurofilament heavy chain decreases expression EXP 2,5-hexanedione results in decreased expression of NEFH protein CTD PMID:19033394 NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351 		JBrowse link
G Nefl neurofilament light chain decreases expression
multiple interactions		 EXP 2,5-hexanedione results in decreased expression of NEFL protein
Glyburide inhibits the reaction [2,5-hexanedione results in decreased expression of NEFL protein]		 CTD PMID:19033394 PMID:32522579 PMID:32860822 NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793 		JBrowse link
G Nefm neurofilament medium chain decreases expression EXP 2,5-hexanedione results in decreased expression of NEFM protein CTD PMID:19033394 NCBI chr15:42,360,449...42,365,753
Ensembl chr15:42,360,454...42,365,755 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions
increases expression		 EXP Glyburide inhibits the reaction [2,5-hexanedione results in increased expression of NLRP3 protein]
2,5-hexanedione results in increased expression of NLRP3 mRNA; 2,5-hexanedione results in increased expression of NLRP3 protein		 CTD PMID:32522579 PMID:32860822 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811 		JBrowse link
G Nos2 nitric oxide synthase 2 increases expression
multiple interactions		 EXP 2,5-hexanedione results in increased expression of NOS2 mRNA
Glyburide inhibits the reaction [2,5-hexanedione results in increased expression of NOS2 mRNA]		 CTD PMID:32522579 PMID:32860822 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nsf N-ethylmaleimide sensitive factor, vesicle fusing ATPase decreases expression EXP 2,5-hexanedione results in decreased expression of NSF protein CTD PMID:19033394 NCBI chr10:88,727,912...88,857,375
Ensembl chr10:88,727,912...88,857,386 		JBrowse link
G Nupr2 nuclear protein 2, transcriptional regulator increases expression EXP 2,5-hexanedione results in increased expression of NUPR2 mRNA CTD PMID:22952946 NCBI chr12:26,800,123...26,803,228
Ensembl chr12:26,799,800...26,803,304 		JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 decreases expression EXP 2,5-hexanedione results in decreased expression of PDIA3 protein CTD PMID:19033394 NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236 		JBrowse link
G Pdlim3 PDZ and LIM domain 3 decreases expression EXP 2,5-hexanedione results in decreased expression of PDLIM3 protein CTD PMID:19033394 NCBI chr16:46,352,460...46,383,680
Ensembl chr16:46,352,467...46,383,657 		JBrowse link
G Pgam1 phosphoglycerate mutase 1 increases expression EXP 2,5-hexanedione results in increased expression of PGAM1 protein CTD PMID:19033394 NCBI chr 1:240,723,832...240,731,443
Ensembl chr 1:240,723,920...240,738,452 		JBrowse link
G Phospho1 phosphoethanolamine/phosphocholine phosphatase 1 increases expression EXP 2,5-hexanedione results in increased expression of PHOSPHO1 mRNA CTD PMID:22952946 NCBI chr10:80,762,062...80,769,596
Ensembl chr10:80,760,792...80,770,342 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha decreases expression ISO 2,5-hexanedione results in decreased expression of PIK3CA mRNA CTD PMID:33197454 NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 decreases expression ISO 2,5-hexanedione results in decreased expression of PIK3R1 protein CTD PMID:33197454 NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631 		JBrowse link
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase increases expression EXP 2,5-hexanedione results in increased expression of PIM1 mRNA CTD PMID:22952946 NCBI chr20:7,554,921...7,559,174
Ensembl chr20:7,554,921...7,559,174 		JBrowse link
G Pkm pyruvate kinase M1/2 increases expression EXP 2,5-hexanedione results in increased expression of PKM protein CTD PMID:19033394 NCBI chr 8:60,057,629...60,079,600
Ensembl chr 8:60,057,402...60,079,599 		JBrowse link
G Pou2f1 POU class 2 homeobox 1 increases expression EXP 2,5-hexanedione results in increased expression of POU2F1 mRNA CTD PMID:22952946 NCBI chr13:78,120,617...78,263,306
Ensembl chr13:78,130,685...78,263,363 		JBrowse link
G Prkcsh PRKCSH beta subunit of glucosidase II decreases expression EXP 2,5-hexanedione results in decreased expression of PRKCSH protein CTD PMID:19033394 NCBI chr 8:20,534,787...20,546,493
Ensembl chr 8:20,534,880...20,546,492 		JBrowse link
G Ptgds prostaglandin D2 synthase increases expression EXP 2,5-hexanedione results in increased expression of PTGDS mRNA CTD PMID:22952946 PMID:27466211 NCBI chr 3:8,281,899...8,284,833
Ensembl chr 3:8,281,899...8,284,833 		JBrowse link
G Pycard PYD and CARD domain containing increases expression EXP 2,5-hexanedione results in increased expression of PYCARD mRNA; 2,5-hexanedione results in increased expression of PYCARD protein CTD PMID:32860822 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Pygb glycogen phosphorylase B decreases expression EXP 2,5-hexanedione results in decreased expression of PYGB protein CTD PMID:19033394 NCBI chr 3:139,611,724...139,658,521
Ensembl chr 3:139,611,749...139,663,553 		JBrowse link
G Pygm glycogen phosphorylase, muscle associated decreases expression EXP 2,5-hexanedione results in decreased expression of PYGM protein CTD PMID:19033394 NCBI chr 1:203,690,550...203,705,369
Ensembl chr 1:203,690,533...203,705,368 		JBrowse link
G Ralgapa2 Ral GTPase activating protein catalytic subunit alpha 2 increases expression EXP 2,5-hexanedione results in increased expression of RALGAPA2 mRNA CTD PMID:22952946 NCBI chr 3:133,658,725...133,938,821
Ensembl chr 3:133,659,761...133,938,916 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP 2,5-hexanedione results in decreased expression of and affects the localization of RELA protein CTD PMID:22337490 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Rtkn2 rhotekin 2 increases expression EXP 2,5-hexanedione results in increased expression of RTKN2 mRNA CTD PMID:22952946 NCBI chr20:20,536,628...20,609,951
Ensembl chr20:20,525,256...20,609,951 		JBrowse link
G S100z S100 calcium binding protein Z increases expression EXP 2,5-hexanedione results in increased expression of S100Z mRNA CTD PMID:22952946 NCBI chr 2:26,737,796...26,753,611
Ensembl chr 2:26,738,776...26,752,390 		JBrowse link
G Sclt1 sodium channel and clathrin linker 1 increases expression EXP 2,5-hexanedione results in increased expression of SCLT1 mRNA CTD PMID:22952946 NCBI chr 2:124,605,445...124,763,964
Ensembl chr 2:124,605,658...124,764,065 		JBrowse link
G Septin8 septin 8 decreases expression EXP 2,5-hexanedione results in decreased expression of SEPTIN8 protein CTD PMID:19033394 NCBI chr10:37,684,649...37,713,704
Ensembl chr10:37,684,639...37,713,174 		JBrowse link
G Sh2d4a SH2 domain containing 4A decreases expression EXP 2,5-hexanedione results in decreased expression of SH2D4A mRNA CTD PMID:22952946 NCBI chr16:21,339,010...21,409,360
Ensembl chr16:21,340,015...21,409,260 		JBrowse link
G Shank3 SH3 and multiple ankyrin repeat domains 3 multiple interactions EXP [carbendazim co-treated with 2,5-hexanedione] affects the expression of SHANK3 mRNA CTD PMID:22382377 NCBI chr 7:120,568,707...120,630,796
Ensembl chr 7:120,570,402...120,630,374 		JBrowse link
G Sil1 SIL1 nucleotide exchange factor increases expression EXP 2,5-hexanedione results in increased expression of SIL1 mRNA CTD PMID:22952946 NCBI chr18:26,872,423...27,104,365
Ensembl chr18:26,872,429...27,104,332 		JBrowse link
G Slc10a7 solute carrier family 10, member 7 increases expression EXP 2,5-hexanedione results in increased expression of SLC10A7 mRNA CTD PMID:22952946 NCBI chr19:29,183,143...29,407,470
Ensembl chr19:29,183,155...29,407,464 		JBrowse link
G Sltm SAFB-like, transcription modulator increases expression EXP 2,5-hexanedione results in increased expression of SLTM mRNA CTD PMID:22952946 NCBI chr 8:71,215,995...71,261,821
Ensembl chr 8:71,216,612...71,261,825 		JBrowse link
G Sod3 superoxide dismutase 3 increases expression EXP 2,5-hexanedione results in increased expression of SOD3 mRNA CTD PMID:22952946 PMID:27466211 NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990 		JBrowse link
G Sppl3 signal peptide peptidase like 3 increases expression EXP 2,5-hexanedione results in increased expression of SPPL3 mRNA CTD PMID:22952946 NCBI chr12:41,515,635...41,600,079
Ensembl chr12:41,515,640...41,600,126 		JBrowse link
G Sptan1 spectrin, alpha, non-erythrocytic 1 decreases expression EXP 2,5-hexanedione results in decreased expression of SPTAN1 protein CTD PMID:19033394 NCBI chr 3:13,241,164...13,306,047
Ensembl chr 3:13,241,217...13,306,046 		JBrowse link
G Stmn1 stathmin 1 decreases expression EXP 2,5-hexanedione results in decreased expression of STMN1 mRNA CTD PMID:22952946 NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154 		JBrowse link
G Strbp spermatid perinuclear RNA binding protein increases expression EXP 2,5-hexanedione results in increased expression of STRBP mRNA CTD PMID:22952946 NCBI chr 3:21,328,310...21,467,753
Ensembl chr 3:21,337,855...21,414,949 		JBrowse link
G Styxl1 serine/threonine/tyrosine interacting-like 1 increases expression EXP 2,5-hexanedione results in increased expression of STYXL1 mRNA CTD PMID:22952946 NCBI chr12:20,907,410...20,940,232
Ensembl chr12:20,907,435...20,939,752 		JBrowse link
G Tax1bp1 Tax1 binding protein 1 increases expression EXP 2,5-hexanedione results in increased expression of TAX1BP1 mRNA CTD PMID:22952946 NCBI chr 4:81,821,991...81,877,906
Ensembl chr 4:81,821,989...81,879,100 		JBrowse link
G Tbc1d5 TBC1 domain family, member 5 increases expression EXP 2,5-hexanedione results in increased expression of TBC1D5 mRNA CTD PMID:22952946 NCBI chr 9:3,503,328...4,017,131
Ensembl chr 9:3,513,623...4,016,913 		JBrowse link
G Tmem192 transmembrane protein 192 increases expression EXP 2,5-hexanedione results in increased expression of TMEM192 mRNA CTD PMID:22952946 NCBI chr16:24,740,166...24,760,994
Ensembl chr16:24,740,124...24,761,021 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression		 EXP Glyburide inhibits the reaction [2,5-hexanedione results in increased expression of TNF mRNA] CTD PMID:32522579 PMID:32860822 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tpi1 triosephosphate isomerase 1 increases expression EXP 2,5-hexanedione results in increased expression of TPI1 mRNA; 2,5-hexanedione results in increased expression of TPI1 protein CTD PMID:19033394 PMID:22952946 NCBI chr 4:157,615,283...157,618,813
Ensembl chr 4:157,615,386...157,619,541 		JBrowse link
G Uba1 ubiquitin-like modifier activating enzyme 1 increases expression EXP 2,5-hexanedione results in increased expression of UBA1 protein CTD PMID:19033394 NCBI chr  X:1,508,700...1,530,677
Ensembl chr  X:1,508,666...1,530,636 		JBrowse link
G Ubn2 ubinuclein 2 increases expression EXP 2,5-hexanedione results in increased expression of UBN2 mRNA CTD PMID:22952946 NCBI chr 4:67,165,278...67,251,562
Ensembl chr 4:67,166,346...67,230,491 		JBrowse link
G Uqcrc2 ubiquinol cytochrome c reductase core protein 2 decreases expression EXP 2,5-hexanedione results in decreased expression of UQCRC2 mRNA CTD PMID:22952946 NCBI chr 1:175,167,933...175,198,499
Ensembl chr 1:175,167,894...175,199,453 		JBrowse link
G Vim vimentin multiple interactions ISO 2,5-hexanedione promotes the reaction [VIM protein binds to VIM protein] CTD PMID:6361548 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187 		JBrowse link
G Xiap X-linked inhibitor of apoptosis decreases expression EXP 2,5-hexanedione results in decreased expression of XIAP mRNA CTD PMID:22337490 NCBI chr  X:120,890,537...120,938,413
Ensembl chr  X:120,897,907...120,934,700 		JBrowse link
G Zfp169 zinc finger protein 169 decreases expression EXP 2,5-hexanedione results in decreased expression of ZFP169 protein CTD PMID:19033394 NCBI chr17:16,139,204...16,167,242
Ensembl chr17:16,139,253...16,169,914 		JBrowse link
G Zfp407 zinc finger protein 407 increases expression EXP 2,5-hexanedione results in increased expression of ZFP407 mRNA CTD PMID:22952946 NCBI chr18:77,571,140...77,970,282
Ensembl chr18:77,571,204...77,974,129 		JBrowse link
hexanal term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acot9 acyl-CoA thioesterase 9 increases methylation ISO n-hexanal results in increased methylation of ACOT9 gene CTD PMID:30002397 NCBI chr  X:40,073,197...40,123,573
Ensembl chr  X:40,064,810...40,123,559 		JBrowse link
G Adh6 alcohol dehydrogenase 6 (class V) affects expression EXP n-hexanal affects the expression of ADH6 mRNA CTD PMID:26880647 NCBI chr 2:226,903,208...226,934,564
Ensembl chr 2:226,903,250...226,934,534 		JBrowse link
G Aire autoimmune regulator increases methylation ISO n-hexanal results in increased methylation of AIRE gene CTD PMID:30002397 NCBI chr20:10,636,058...10,651,060
Ensembl chr20:10,636,123...10,651,060 		JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B1 affects reduction
increases reduction		 ISO AKR1B1 protein affects the reduction of n-hexanal; AKR1B1 protein affects the reduction of n-hexanal analog
AKR1B1 protein results in increased reduction of n-hexanal		 CTD PMID:9890881 PMID:11306073 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157 		JBrowse link
G Akr7a2 aldo-keto reductase family 7, member A2 decreases response to substance ISO AKR7A5 protein results in decreased susceptibility to n-hexanal CTD PMID:24590062 NCBI chr 5:151,552,375...151,560,914
Ensembl chr 5:151,552,343...151,560,909 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases oxidation ISO ALDH1A1 protein results in increased oxidation of n-hexanal CTD PMID:23220587 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961 		JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 increases oxidation EXP ALDH1A2 protein results in increased oxidation of n-hexanal CTD PMID:23220587 NCBI chr 8:71,877,850...71,957,107
Ensembl chr 8:71,877,850...71,957,107 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member affects metabolic processing ISO ALDH2 protein polymorphism affects the metabolism of n-hexanal CTD PMID:11744614 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521 		JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 affects metabolic processing
decreases response to substance		 ISO ALDH3A1 protein affects the metabolism of n-hexanal
ALDH3A1 protein results in decreased susceptibility to n-hexanal		 CTD PMID:11306050 NCBI chr10:45,892,993...45,902,680
Ensembl chr10:45,892,924...45,902,681 		JBrowse link
G Aldh3b1 aldehyde dehydrogenase 3 family, member B1 affects binding
decreases response to substance		 ISO n-hexanal binds to ALDH3B1 protein
ALDH3B1 protein results in decreased susceptibility to n-hexanal		 CTD PMID:20699116 NCBI chr 1:201,145,309...201,162,675
Ensembl chr 1:201,145,309...201,163,921 		JBrowse link
G Aldh7a1 aldehyde dehydrogenase 7 family, member A1 decreases response to substance ISO ALDH7A1 protein results in decreased susceptibility to n-hexanal CTD PMID:21338592 NCBI chr18:50,003,242...50,042,193
Ensembl chr18:50,009,934...50,042,193 		JBrowse link
G B3galt4 Beta-1,3-galactosyltransferase 4 decreases expression ISO n-hexanal results in decreased expression of B3GALT4 mRNA CTD PMID:25014914 NCBI chr20:4,936,089...4,937,664
Ensembl chr20:4,931,768...4,938,315 		JBrowse link
G Bmp10 bone morphogenetic protein 10 increases methylation ISO n-hexanal results in increased methylation of BMP10 gene CTD PMID:30002397 NCBI chr 4:119,872,066...119,877,694
Ensembl chr 4:119,872,045...119,878,627 		JBrowse link
G C1h9orf57 similar to human chromosome 9 open reading frame 57 decreases methylation ISO n-hexanal results in decreased methylation of C9ORF57 gene CTD PMID:30002397 NCBI chr 1:219,079,683...219,084,806
Ensembl chr 1:219,079,683...219,084,806 		JBrowse link
G Car9 carbonic anhydrase 9 decreases expression ISO n-hexanal results in decreased expression of CA9 mRNA CTD PMID:25014914 NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838 		JBrowse link
G Ccl12 C-C motif chemokine ligand 12 affects expression EXP n-hexanal affects the expression of CCL12 mRNA CTD PMID:26880647 NCBI chr10:67,070,230...67,071,780
Ensembl chr10:67,070,230...67,071,780 		JBrowse link
G Ccna1 cyclin A1 increases methylation ISO n-hexanal results in increased methylation of CCNA1 gene CTD PMID:30002397 NCBI chr 2:139,231,738...139,278,066
Ensembl chr 2:139,201,074...139,243,157 		JBrowse link
G Ccnb1ip1 cyclin B1 interacting protein 1 increases methylation ISO n-hexanal results in increased methylation of CCNB1IP1 gene CTD PMID:30002397 NCBI chr15:24,014,905...24,031,357
Ensembl chr15:24,014,908...24,028,475 		JBrowse link
G Cebpd CCAAT/enhancer binding protein delta affects expression EXP n-hexanal affects the expression of CEBPD mRNA CTD PMID:26880647 NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829 		JBrowse link
G Cep85 centrosomal protein 85 increases methylation ISO n-hexanal results in increased methylation of CEP85 gene CTD PMID:30002397 NCBI chr 5:146,356,571...146,404,155
Ensembl chr 5:146,356,576...146,404,060 		JBrowse link
G Chd3 chromodomain helicase DNA binding protein 3 increases methylation ISO n-hexanal results in increased methylation of CHD3 gene CTD PMID:30002397 NCBI chr10:54,063,629...54,090,030
Ensembl chr10:54,063,629...54,090,047 		JBrowse link
G Chga chromogranin A increases expression EXP n-hexanal results in increased expression of CHGA mRNA CTD PMID:26403475 NCBI chr 6:121,696,051...121,707,399
Ensembl chr 6:121,696,051...121,707,398 		JBrowse link
G Cox17 cytochrome c oxidase copper chaperone COX17 increases methylation ISO n-hexanal results in increased methylation of COX17 gene CTD PMID:30002397 NCBI chr11:62,400,733...62,406,507 JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO n-hexanal results in increased expression of CYP1A1 mRNA CTD PMID:25014914 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 affects expression EXP n-hexanal affects the expression of DDIT4 mRNA CTD PMID:26880647 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105 		JBrowse link
G Dhrs9 dehydrogenase/reductase 9 increases expression ISO n-hexanal results in increased expression of DHRS9 mRNA CTD PMID:25014914 NCBI chr 3:54,147,834...54,170,052
Ensembl chr 3:54,147,803...54,220,241 		JBrowse link
G Dnaaf2 dynein, axonemal, assembly factor 2 increases methylation ISO n-hexanal results in increased methylation of DNAAF2 gene CTD PMID:30002397 NCBI chr 6:87,661,101...87,670,267
Ensembl chr 6:87,660,821...87,670,199 		JBrowse link
G H2bc6 H2B clustered histone 6 increases methylation ISO n-hexanal results in increased methylation of H2BC6 gene CTD PMID:30002397 NCBI chr17:41,520,775...41,521,238 JBrowse link
G Hmox1 heme oxygenase 1 decreases expression ISO n-hexanal results in decreased expression of HMOX1 mRNA CTD PMID:28947239 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hsd17b11 hydroxysteroid (17-beta) dehydrogenase 11 increases methylation ISO n-hexanal results in increased methylation of HSD17B11 gene CTD PMID:30002397 NCBI chr14:5,693,304...5,743,157
Ensembl chr14:5,711,964...5,743,161 		JBrowse link
G Jchain joining chain of multimeric IgA and IgM increases methylation ISO n-hexanal results in increased methylation of JCHAIN gene CTD PMID:30002397 NCBI chr14:19,538,927...19,547,023
Ensembl chr14:19,538,952...19,546,298 		JBrowse link
G Kcnf1 potassium voltage-gated channel modifier subfamily F member 1 increases methylation ISO n-hexanal results in increased methylation of KCNF1 gene CTD PMID:30002397 NCBI chr 6:39,962,301...39,964,979
Ensembl chr 6:39,962,307...39,964,979 		JBrowse link
G Kif7 kinesin family member 7 increases methylation ISO n-hexanal results in increased methylation of KIF7 gene CTD PMID:30002397 NCBI chr 1:133,639,487...133,658,539
Ensembl chr 1:133,640,065...133,658,576 		JBrowse link
G Klf2 KLF transcription factor 2 affects expression EXP n-hexanal affects the expression of KLF2 mRNA CTD PMID:26880647 NCBI chr16:17,521,107...17,523,739
Ensembl chr16:17,514,552...17,523,944 		JBrowse link
G Lhfpl3 LHFPL tetraspan subfamily member 3 increases methylation ISO n-hexanal results in increased methylation of LHFPL3 gene CTD PMID:30002397
G Lrrc74a leucine rich repeat containing 74A increases methylation ISO n-hexanal results in increased methylation of LRRC74A gene CTD PMID:30002397 NCBI chr 6:106,386,276...106,417,112
Ensembl chr 6:106,386,347...106,416,193 		JBrowse link
G Mfn1 mitofusin 1 increases methylation ISO n-hexanal results in increased methylation of MFN1 gene CTD PMID:30002397 NCBI chr 2:115,313,380...115,359,651
Ensembl chr 2:115,313,401...115,359,640 		JBrowse link
G Mir101a microRNA 101a decreases expression EXP n-hexanal results in decreased expression of MIR101A mRNA CTD PMID:26403475 NCBI chr 5:115,966,332...115,966,406
Ensembl chr 5:115,966,328...115,966,410 		JBrowse link
G Mir1224 microRNA 1224 decreases expression EXP n-hexanal results in decreased expression of MIR1224 mRNA CTD PMID:26403475 NCBI chr11:80,306,902...80,306,986
Ensembl chr11:80,306,902...80,306,986 		JBrowse link
G Mir1249 microRNA 1249 decreases expression EXP n-hexanal results in decreased expression of MIR1249 mRNA CTD PMID:26403475 NCBI chr 7:116,075,593...116,075,712
Ensembl chr 7:116,075,593...116,075,712 		JBrowse link
G Mir128-1 microRNA 128-1 increases methylation ISO n-hexanal results in increased methylation of MIR128-1 gene CTD PMID:30002397 NCBI chr13:39,699,449...39,699,530
Ensembl chr13:39,699,449...39,699,530 		JBrowse link
G Mir1306 microRNA 1306 decreases expression EXP n-hexanal results in decreased expression of MIR1306 mRNA CTD PMID:26403475 NCBI chr11:82,709,651...82,709,723
Ensembl chr11:82,709,637...82,709,719 		JBrowse link
G Mir132 microRNA 132 increases expression EXP n-hexanal results in increased expression of MIR132 mRNA CTD PMID:26403475 NCBI chr10:60,023,696...60,023,796
Ensembl chr10:60,023,696...60,023,796 		JBrowse link
G Mir136 microRNA 136 decreases expression EXP n-hexanal results in decreased expression of MIR136 mRNA CTD PMID:26403475 NCBI chr 6:128,549,096...128,549,177
Ensembl chr 6:128,549,096...128,549,177 		JBrowse link
G Mir145 microRNA 145 decreases expression EXP n-hexanal results in decreased expression of MIR145 mRNA CTD PMID:26403475 NCBI chr18:55,099,640...55,099,727
Ensembl chr18:55,099,640...55,099,727 		JBrowse link
G Mir153 microRNA 153 decreases expression EXP n-hexanal results in decreased expression of MIR153 mRNA CTD PMID:26403475 NCBI chr 6:138,163,595...138,163,681
Ensembl chr 6:138,163,595...138,163,681 		JBrowse link
G Mir181b1 microRNA 181b-1 decreases expression EXP n-hexanal results in decreased expression of MIR181B1 mRNA CTD PMID:26403475 NCBI chr13:49,485,688...49,485,797
Ensembl chr13:49,485,688...49,485,797 		JBrowse link
G Mir184 microRNA 184 decreases expression EXP n-hexanal results in decreased expression of MIR184 mRNA CTD PMID:26403475 NCBI chr 8:90,343,134...90,343,210
Ensembl chr 8:90,343,134...90,343,210 		JBrowse link
G Mir188 microRNA 188 decreases expression EXP n-hexanal results in decreased expression of MIR188 mRNA CTD PMID:26403475 NCBI chr  X:15,247,715...15,247,794
Ensembl chr  X:15,247,715...15,247,794 		JBrowse link
G Mir190 microRNA 190 decreases expression EXP n-hexanal results in decreased expression of MIR190 mRNA CTD PMID:26403475 NCBI chr 8:67,850,987...67,851,071
Ensembl chr 8:67,850,987...67,851,071 		JBrowse link
G Mir193a microRNA 193a decreases expression EXP n-hexanal results in decreased expression of MIR193A mRNA CTD PMID:26403475 NCBI chr10:64,672,343...64,672,454
Ensembl chr10:64,672,343...64,672,454 		JBrowse link
G Mir200a microRNA 200a decreases expression EXP n-hexanal results in decreased expression of MIR200A mRNA CTD PMID:26403475 NCBI chr 5:166,648,494...166,648,582 JBrowse link
G Mir217 microRNA 217 decreases expression EXP n-hexanal results in decreased expression of MIR217 mRNA CTD PMID:26403475 NCBI chr14:102,531,505...102,531,609
Ensembl chr14:102,531,505...102,531,609 		JBrowse link
G Mir221 microRNA 221 decreases expression EXP n-hexanal results in decreased expression of MIR221 mRNA CTD PMID:26403475 NCBI chr  X:3,429,465...3,429,573
Ensembl chr  X:3,429,465...3,429,573 		JBrowse link
G Mir224 microRNA 224 decreases expression EXP n-hexanal results in decreased expression of MIR224 mRNA CTD PMID:26403475 NCBI chr  X:150,065,088...150,065,169
Ensembl chr  X:150,065,088...150,065,169 		JBrowse link
G Mir299b microRNA 299b decreases expression EXP n-hexanal results in decreased expression of MIR299 mRNA CTD PMID:26403475 NCBI chr 6:128,723,635...128,723,752
Ensembl chr 6:128,723,635...128,723,752 		JBrowse link
G Mir29b2 microRNA 29b-2 decreases expression EXP n-hexanal results in decreased expression of MIR29B2 mRNA CTD PMID:26403475 NCBI chr13:106,570,371...106,570,451
Ensembl chr13:106,570,367...106,570,456 		JBrowse link
G Mir326 microRNA 326 decreases expression EXP n-hexanal results in decreased expression of MIR326 mRNA CTD PMID:26403475 NCBI chr 1:153,854,029...153,854,123
Ensembl chr 1:153,854,029...153,854,123 		JBrowse link
G Mir328b microRNA 328b decreases expression EXP n-hexanal results in decreased expression of MIR328B mRNA CTD PMID:26403475 NCBI chr14:43,663,068...43,663,185
Ensembl chr14:43,663,068...43,663,185 		JBrowse link
G Mir337 microRNA 337 decreases expression EXP n-hexanal results in decreased expression of MIR337 mRNA CTD PMID:26403475 NCBI chr 6:128,538,903...128,538,999
Ensembl chr 6:128,538,902...128,538,998 		JBrowse link
G Mir3568 microRNA 3568 decreases expression EXP n-hexanal results in decreased expression of MIR3568 mRNA CTD PMID:26403475 NCBI chr10:10,661,344...10,661,444
Ensembl chr10:10,661,344...10,661,444 		JBrowse link
G Mir3582 microRNA 3582 decreases expression EXP n-hexanal results in decreased expression of MIR3582 mRNA CTD PMID:26403475 NCBI chr18:1,885,063...1,885,180
Ensembl chr18:1,885,063...1,885,180 		JBrowse link
G Mir3585 microRNA 3585 decreases expression EXP n-hexanal results in decreased expression of MIR3585 mRNA CTD PMID:26403475 NCBI chr  X:146,662,031...146,662,148
Ensembl chr  X:146,662,031...146,662,148 		JBrowse link
G Mir3594 microRNA 3594 decreases expression EXP n-hexanal results in decreased expression of MIR3594 mRNA CTD PMID:26403475 NCBI chr10:105,347,412...105,347,476
Ensembl chr10:105,347,412...105,347,476 		JBrowse link
G Mir381 microRNA 381 decreases expression EXP n-hexanal results in decreased expression of MIR381 mRNA CTD PMID:26403475 NCBI chr 6:128,740,976...128,741,036 JBrowse link
G Mir411 microRNA 411 decreases expression EXP n-hexanal results in decreased expression of MIR411 mRNA CTD PMID:26403475 NCBI chr 6:128,723,189...128,723,264
Ensembl chr 6:128,723,184...128,723,279 		JBrowse link
G Mir425 microRNA 425 decreases expression EXP n-hexanal results in decreased expression of MIR425 mRNA CTD PMID:26403475 NCBI chr 8:109,264,555...109,264,637
Ensembl chr 8:109,264,555...109,264,637 		JBrowse link
G Mir431 microRNA 431 decreases expression EXP n-hexanal results in decreased expression of MIR431 mRNA CTD PMID:26403475 NCBI chr 6:128,544,210...128,544,323
Ensembl chr 6:128,544,210...128,544,323 		JBrowse link
G Mir433 microRNA 433 decreases expression EXP n-hexanal results in decreased expression of MIR433 mRNA CTD PMID:26403475 NCBI chr 6:128,545,119...128,545,211
Ensembl chr 6:128,545,112...128,545,217 		JBrowse link
G Mir541 microRNA 541 decreases expression EXP n-hexanal results in decreased expression of MIR541 mRNA CTD PMID:26403475 NCBI chr 6:128,757,016...128,757,105
Ensembl chr 6:128,757,016...128,757,105 		JBrowse link
G Mir6315 microRNA 6315 decreases expression EXP n-hexanal results in decreased expression of MIR6315 mRNA CTD PMID:26403475 NCBI chr 1:203,363,908...203,364,008
Ensembl chr 1:203,363,908...203,364,008 		JBrowse link
G Mir6317-1 microRNA mir-6317-1 decreases expression EXP n-hexanal results in decreased expression of MIR6317-1 mRNA CTD PMID:26403475 NCBI chr 1:239,398,926...239,399,052
Ensembl chr 1:239,398,926...239,399,052 		JBrowse link
G Mir6332 microRNA 6332 decreases expression EXP n-hexanal results in decreased expression of MIR6332 mRNA CTD PMID:26403475 NCBI chr 5:160,837,304...160,837,424
Ensembl chr 5:160,837,304...160,837,424 		JBrowse link
G Mir664-2 microRNA 664-2 decreases expression EXP n-hexanal results in decreased expression of MIR664-2 mRNA CTD PMID:26403475 NCBI chr13:96,793,099...96,793,157
Ensembl chr13:96,793,099...96,793,157 		JBrowse link
G Mir9 microRNA 9 decreases expression EXP n-hexanal results in decreased expression of MIR7B mRNA CTD PMID:26403475 NCBI chr 9:1,080,274...1,080,383
Ensembl chr 9:1,080,274...1,080,383 		JBrowse link
G Mirlet7f-1 microRNA let7f-1 decreases expression EXP n-hexanal results in decreased expression of MIRLET7F-1 mRNA CTD PMID:26403475 NCBI chr17:16,114,130...16,114,226
Ensembl chr17:16,114,130...16,114,226 		JBrowse link
G Mmp9 matrix metallopeptidase 9 increases secretion ISO n-hexanal results in increased secretion of MMP9 protein CTD PMID:28947239 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Mrps18a mitochondrial ribosomal protein S18A increases methylation ISO n-hexanal results in increased methylation of MRPS18A gene CTD PMID:30002397 NCBI chr 9:14,853,322...14,869,819
Ensembl chr 9:14,853,291...14,869,835 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression ISO n-hexanal results in decreased expression of MYC mRNA CTD PMID:12921975 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Myt1 myelin transcription factor 1 increases methylation ISO n-hexanal results in increased methylation of MYT1 gene CTD PMID:30002397 NCBI chr 3:168,890,466...168,950,341
Ensembl chr 3:168,886,089...168,950,341 		JBrowse link
G Nfxl1 nuclear transcription factor, X-box binding-like 1 increases methylation ISO n-hexanal results in increased methylation of NFXL1 gene CTD PMID:30002397 NCBI chr14:35,626,086...35,667,505
Ensembl chr14:35,626,066...35,667,498 		JBrowse link
G Nmbr neuromedin B receptor increases methylation ISO n-hexanal results in increased methylation of NMBR gene CTD PMID:30002397 NCBI chr 1:9,115,033...9,146,081
Ensembl chr 1:9,134,889...9,145,462 		JBrowse link
G Nuf2 NUF2 component of NDC80 kinetochore complex increases methylation ISO n-hexanal results in increased methylation of NUF2 gene CTD PMID:30002397 NCBI chr13:81,693,675...81,722,765
Ensembl chr13:81,693,598...81,722,766 		JBrowse link
G Or10z1 olfactory receptor family 10 subfamily Z member 1 increases methylation ISO n-hexanal results in increased methylation of OR10Z1 gene CTD PMID:30002397 NCBI chr13:86,281,535...86,282,476
Ensembl chr13:86,278,626...86,283,642 		JBrowse link
G Pcdha10 protocadherin alpha 10 increases methylation ISO n-hexanal results in increased methylation of PCDHA10 gene CTD PMID:30002397 Ensembl chr18:28,581,225...28,846,211 JBrowse link
G Pcdha9 protocadherin alpha 9 increases methylation ISO n-hexanal results in increased methylation of PCDHA9 gene CTD PMID:30002397 Ensembl chr18:28,581,225...28,846,211 JBrowse link
G Pde4a phosphodiesterase 4A increases methylation ISO n-hexanal results in increased methylation of PDE4A gene CTD PMID:30002397 NCBI chr 8:19,690,816...19,753,538
Ensembl chr 8:19,703,290...19,751,961 		JBrowse link
G Pex2 peroxisomal biogenesis factor 2 increases methylation ISO n-hexanal results in increased methylation of PEX2 gene CTD PMID:30002397 NCBI chr 2:96,050,380...96,072,928
Ensembl chr 2:96,045,958...96,073,404 		JBrowse link
G Phactr1 phosphatase and actin regulator 1 increases methylation ISO n-hexanal results in increased methylation of PHACTR1 gene CTD PMID:30002397 NCBI chr17:21,560,364...22,040,166
Ensembl chr17:21,562,721...22,039,831 		JBrowse link
G Pik3c2a phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha increases methylation ISO n-hexanal results in increased methylation of PIK3C2A gene CTD PMID:30002397 NCBI chr 1:170,577,942...170,684,353
Ensembl chr 1:170,577,942...170,683,472 		JBrowse link
G Plppr5 phospholipid phosphatase related 5 increases methylation ISO n-hexanal results in increased methylation of PLPPR5 gene CTD PMID:30002397 NCBI chr 2:205,525,466...205,737,892
Ensembl chr 2:205,458,176...205,717,599 		JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta increases methylation ISO n-hexanal results in increased methylation of PRKACB gene CTD PMID:30002397 NCBI chr 2:235,636,878...235,726,928
Ensembl chr 2:235,636,885...235,726,198 		JBrowse link
G Reg1a regenerating family member 1 alpha increases methylation ISO n-hexanal results in increased methylation of REG1A gene CTD PMID:30002397 NCBI chr 4:110,892,451...110,895,115
Ensembl chr 4:110,892,453...110,895,570 		JBrowse link
G Scarna3 small Cajal body-specific RNA 3 decreases expression EXP n-hexanal results in decreased expression of SCARNA3 mRNA CTD PMID:26403475 NCBI chr 6:99,222,432...99,222,521
Ensembl chr 6:99,222,432...99,222,521 		JBrowse link
G Slc39a5 solute carrier family 39 member 5 decreases expression ISO n-hexanal results in decreased expression of SLC39A5 mRNA CTD PMID:25014914 NCBI chr 7:822,873...830,865
Ensembl chr 7:824,818...830,242 		JBrowse link
G Slk STE20-like kinase increases methylation ISO n-hexanal results in increased methylation of SLK gene CTD PMID:30002397 NCBI chr 1:246,473,712...246,529,643
Ensembl chr 1:246,473,712...246,526,530 		JBrowse link
G Snca synuclein alpha increases methylation ISO n-hexanal results in increased methylation of SNCA gene CTD PMID:30002397 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262 		JBrowse link
G Snora58 small nucleolar RNA, H/ACA box 58 decreases expression EXP n-hexanal results in decreased expression of SNORA58 mRNA CTD PMID:26403475 NCBI chr 6:107,080,945...107,081,020
Ensembl chr 6:107,080,945...107,081,020 		JBrowse link
G Spink4 serine peptidase inhibitor, Kazal type 4 increases methylation ISO n-hexanal results in increased methylation of SPINK4 gene CTD PMID:30002397 NCBI chr 5:56,043,936...56,064,841
Ensembl chr 5:55,981,624...56,064,795 		JBrowse link
G Stpg4 sperm-tail PG-rich repeat containing 4 increases methylation ISO n-hexanal results in increased methylation of STPG4 gene CTD PMID:30002397 NCBI chr 6:7,108,827...7,158,519
Ensembl chr 6:7,108,869...7,151,390 		JBrowse link
G Tdrkh tudor and KH domain containing increases methylation ISO n-hexanal results in increased methylation of TDRKH gene CTD PMID:30002397 NCBI chr 2:182,049,175...182,071,516
Ensembl chr 2:182,049,215...182,070,755 		JBrowse link
G Thumpd3 THUMP domain containing 3 increases methylation ISO n-hexanal results in increased methylation of THUMPD3 gene CTD PMID:30002397 NCBI chr 4:146,185,422...146,209,802
Ensembl chr 4:146,185,503...146,211,246 		JBrowse link
G Tnf tumor necrosis factor increases expression ISO n-hexanal results in increased expression of TNF mRNA CTD PMID:28947239 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tp53 tumor protein p53 decreases expression ISO n-hexanal results in decreased expression of TP53 mRNA CTD PMID:12921975 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Trim27 tripartite motif-containing 27 increases methylation ISO n-hexanal results in increased methylation of TRIM27 gene CTD PMID:30002397 NCBI chr17:43,538,282...43,550,633
Ensembl chr17:43,538,285...43,550,643 		JBrowse link
G Ubxn4 UBX domain protein 4 increases methylation ISO n-hexanal results in increased methylation of UBXN4 gene CTD PMID:30002397 NCBI chr13:39,740,064...39,772,493
Ensembl chr13:39,740,107...39,772,491 		JBrowse link
G Wdr75 WD repeat domain 75 increases methylation ISO n-hexanal results in increased methylation of WDR75 gene CTD PMID:30002397 NCBI chr 9:47,903,214...47,933,399
Ensembl chr 9:47,903,200...47,933,399 		JBrowse link
G Zfhx2 zinc finger homeobox 2 increases methylation ISO n-hexanal results in increased methylation of ZFHX2 gene CTD PMID:30002397 NCBI chr15:28,533,155...28,565,667
Ensembl chr15:28,533,156...28,565,128 		JBrowse link
hexane-1,6-diamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adgrl3 adhesion G protein-coupled receptor L3 increases abundance ISO ADGRL3 gene modified form results in increased abundance of 1,6-diaminohexane CTD PMID:25445006 NCBI chr14:26,336,320...27,104,060
Ensembl chr14:26,368,277...27,105,860 		JBrowse link
G Mpo myeloperoxidase multiple interactions ISO [1,6-diaminohexane binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; [1,6-diaminohexane binds to TEMPO] inhibits the reaction [MPO protein results in increased degradation of Hydrogen Peroxide]; [1,6-diaminohexane binds to TEMPO] inhibits the reaction [MPO protein results in increased oxidation of Nitric Oxide]; Heparin inhibits the reaction [[1,6-diaminohexane binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]] CTD PMID:34085520 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Scara5 scavenger receptor class A, member 5 increases abundance ISO SCARA5 gene modified form results in increased abundance of 1,6-diaminohexane CTD PMID:25445006 NCBI chr15:39,880,017...39,985,007
Ensembl chr15:39,880,035...39,983,373 		JBrowse link
monohexyl phthalate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsf1 heat shock transcription factor 1 increases activity ISO mono-n-hexyl phthalate results in increased activity of HSF1 protein CTD PMID:34170685 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha affects binding ISO mono-n-hexyl phthalate binds to PPARA protein CTD PMID:23843199 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Ppard peroxisome proliferator-activated receptor delta affects binding ISO mono-n-hexyl phthalate binds to PPARB protein CTD PMID:23843199 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma affects binding ISO mono-n-hexyl phthalate binds to PPARG protein CTD PMID:23843199 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19838
    role 19814
      biological role 19812
        aetiopathogenetic role 19192
          neurotoxin 18180
            hexane 435
              1-iminohexane-2,3,4,5-tetrol 0
              1-isothiocyanato-6-(methylsulfanyl)hexane 0
              1-nitrohexane 0
              2,3,5-trimethylhexane 0
              2,4-dimethylhexane 0
              2,5-hexanedione 198
              2-hexanamine 0
              3-hexanone 0
              3-mercaptohexanol + 0
              3-methoxy-3-methylhexane 0
              5-iminohexane-1,2,3,4,6-pentol 0
              7-(methylthio)heptanonitrile oxide 0
              hexanal 108
              hexane-1,6-diamine + 3
              hexane-1,6-diol + 0
              hexane-2,5-diol + 0
              hexanol + 4
              hexyl group 0
              perfluorohexane 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19838
    subatomic particle 19836
      composite particle 19836
        hadron 19836
          baryon 19836
            nucleon 19836
              atomic nucleus 19836
                atom 19836
                  main group element atom 19786
                    main group molecular entity 19786
                      s-block molecular entity 19624
                        hydrogen molecular entity 19611
                          hydrides 19117
                            organic hydride 18687
                              organic fundamental parent 18687
                                hydrocarbon 18432
                                  alkane 14578
                                    hexane 435
                                      1-iminohexane-2,3,4,5-tetrol 0
                                      1-isothiocyanato-6-(methylsulfanyl)hexane 0
                                      1-nitrohexane 0
                                      2,3,5-trimethylhexane 0
                                      2,4-dimethylhexane 0
                                      2,5-hexanedione 198
                                      2-hexanamine 0
                                      3-hexanone 0
                                      3-mercaptohexanol + 0
                                      3-methoxy-3-methylhexane 0
                                      5-iminohexane-1,2,3,4,6-pentol 0
                                      7-(methylthio)heptanonitrile oxide 0
                                      hexanal 108
                                      hexane-1,6-diamine + 3
                                      hexane-1,6-diol + 0
                                      hexane-2,5-diol + 0
                                      hexanol + 4
                                      hexyl group 0
                                      perfluorohexane 0
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