Gene: Gfap (glial fibrillary acidic protein) Rattus norvegicus
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Symbol: Gfap
Name: glial fibrillary acidic protein
Description: ENCODES a protein that exhibits integrin binding; kinase binding; structural constituent of cytoskeleton; INVOLVED IN positive regulation of glial cell proliferation; regulation of chaperone-mediated autophagy; response to wounding; PARTICIPATES IN chaperone mediated autophagy pathway; ASSOCIATED WITH Brain Edema; brain edema; Head Injuries, Closed; FOUND IN astrocyte projection; cytoplasmic side of lysosomal membrane; astrocyte end-foot (ortholog); INTERACTS WITH (+)-alpha-tocopherol; (RS)-amphetamine; 1,3,5-trinitro-1,3,5-triazinane
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: glial fibrillary acidic protein alpha; glial fibrillary acidic protein delta; intermediate filament
Orthologs:
Homo sapiens (human) : GFAP (glial fibrillary acidic protein)  HGNC  AGR
Mus musculus (house mouse) : Gfap (glial fibrillary acidic protein)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Gfap (glial fibrillary acidic protein)
Pan paniscus (bonobo/pygmy chimpanzee) : GFAP (glial fibrillary acidic protein)
Canis lupus familiaris (dog) : GFAP (glial fibrillary acidic protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gfap (glial fibrillary acidic protein)
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Allele / Splice: Gfapem1Ionsz  
Genetic Models: SD-Gfapem1Ionsz
Is Marker For: Strains:   F344/NRrrc   SD-Tg(Gfap-Tk1)Jog  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01090,990,762 - 90,999,435 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01090,763,150 - 90,771,823 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41092,059,881 - 92,068,555 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11092,074,249 - 92,082,949 (-)NCBI
Celera1086,555,367 - 86,564,160 (-)NCBICelera
Cytogenetic Map10q32.1NCBI
RH 3.4 Map10920.49RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Gfap
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2679
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2017-11-14
Status: ACTIVE