Mir3582 (microRNA 3582) - Rat Genome Database

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Gene: Mir3582 (microRNA 3582) Rattus norvegicus
Analyze
Symbol: Mir3582
Name: microRNA 3582
RGD ID: 4888581
Description: Predicted to enable mRNA 3'-UTR binding activity and mRNA base-pairing translational repressor activity. Predicted to be involved in several processes, including negative regulation of low-density lipoprotein particle clearance; negative regulation of vascular associated smooth muscle cell proliferation; and regulation of gene expression. Predicted to act upstream of or within several processes, including cellular response to leukemia inhibitory factor; miRNA-mediated post-transcriptional gene silencing; and negative regulation of osteoblast differentiation. Predicted to be located in extracellular space; INTERACTS WITH hexanal; warfarin (ortholog).
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: microRNA mir-3582; Mir133c; rno-mir-133c; rno-mir-3582
RGD Orthologs
Human
Mouse
Dog
Pig
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8182,157,853 - 2,157,970 (+)NCBIGRCr8
mRatBN7.2181,885,063 - 1,885,180 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl181,885,063 - 1,885,180 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx182,114,703 - 2,114,820 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0182,902,404 - 2,902,521 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0182,116,585 - 2,116,702 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0182,052,459 - 2,052,576 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl182,052,459 - 2,052,576 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0182,085,438 - 2,085,555 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera181,764,854 - 1,764,971 (+)NCBICelera
Cytogenetic Map18p13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
hexanal  (EXP)
warfarin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:16381832   PMID:19015276   PMID:19188439   PMID:20403161   PMID:20439489   PMID:21628588   PMID:24205035  


Genomics

Comparative Map Data
Mir3582
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8182,157,853 - 2,157,970 (+)NCBIGRCr8
mRatBN7.2181,885,063 - 1,885,180 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl181,885,063 - 1,885,180 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx182,114,703 - 2,114,820 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0182,902,404 - 2,902,521 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0182,116,585 - 2,116,702 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0182,052,459 - 2,052,576 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl182,052,459 - 2,052,576 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0182,085,438 - 2,085,555 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera181,764,854 - 1,764,971 (+)NCBICelera
Cytogenetic Map18p13NCBI
MIR133A2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382062,564,912 - 62,565,013 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2062,564,912 - 62,565,013 (+)EnsemblGRCh38hg38GRCh38
GRCh372061,162,119 - 61,162,220 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362060,572,563 - 60,572,664 (+)NCBINCBI36Build 36hg18NCBI36
Celera2057,872,455 - 57,872,556 (+)NCBICelera
Cytogenetic Map20q13.33NCBI
HuRef2057,916,762 - 57,916,863 (+)NCBIHuRef
CHM1_12061,063,178 - 61,063,279 (+)NCBICHM1_1
T2T-CHM13v2.02064,363,437 - 64,363,538 (+)NCBIT2T-CHM13v2.0
Mir133a-2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392180,040,172 - 180,040,275 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2180,040,172 - 180,040,275 (+)EnsemblGRCm39 Ensembl
GRCm382180,398,379 - 180,398,482 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2180,398,379 - 180,398,482 (+)EnsemblGRCm38mm10GRCm38
MGSCv372180,133,084 - 180,133,187 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera2184,483,296 - 184,483,399 (+)NCBICelera
Cytogenetic Map2H4NCBI
cM Map2102.93NCBI
MIR133C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12446,490,501 - 46,490,586 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2446,490,497 - 46,490,588 (+)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.02447,360,810 - 47,360,895 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.12446,462,042 - 46,462,127 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02446,585,253 - 46,585,338 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02447,339,810 - 47,339,895 (+)NCBIUU_Cfam_GSD_1.0
MIR133A-1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1761,904,781 - 61,904,883 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11761,904,781 - 61,904,883 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21769,274,653 - 69,274,755 (-)NCBISscrofa10.2Sscrofa10.2susScr3

miRNA Target Status

Predicted Targets
Summary Value
Count of predictions:8104
Count of gene targets:5592
Count of transcripts:6012
Interacting mature miRNAs:rno-miR-133c
Prediction methods:Microtar, Miranda, Pita, Pita,Microtar, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8552968Pigfal19Plasma insulin-like growth factor 1 level QTL 1911.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)18125758124Rat
9590248Scort10Serum corticosterone level QTL 1019.710.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)18125758124Rat
2312598Bp340Blood pressure QTL 3400.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)18130558703Rat
2300180Bmd67Bone mineral density QTL 674.80.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)18134291613Rat
2293661Bss50Bone structure and strength QTL 504.640.0003lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)18134291613Rat
61388Bp2Blood pressure QTL 23.23arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)18135374722Rat
9589153Insul31Insulin level QTL 317.150.05blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)18142547119Rat

Markers in Region
RH139837  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2181,884,892 - 1,885,066 (+)MAPPERmRatBN7.2
Rnor_6.0182,052,289 - 2,052,462NCBIRnor6.0
Rnor_5.0182,085,268 - 2,085,441UniSTSRnor5.0
RGSC_v3.4182,189,027 - 2,189,200UniSTSRGSC3.4
Celera181,764,684 - 1,764,857UniSTS
RH 3.4 Map189.7UniSTS
Cytogenetic Map18p13UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 7 8 10 1 3 7 8
Low 2 6 31 15 19 15 1 29 16 14 4
Below cutoff 2 2 2 2 4 2 6

Sequence

Nucleotide Sequences
RefSeq Transcripts NR_037376 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000053774
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl181,885,063 - 1,885,180 (+)Ensembl
Rnor_6.0 Ensembl182,052,459 - 2,052,576 (+)Ensembl
RefSeq Acc Id: NR_037376
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8182,157,853 - 2,157,970 (+)NCBI
mRatBN7.2181,885,063 - 1,885,180 (+)NCBI
Rnor_6.0182,052,459 - 2,052,576 (+)NCBI
Rnor_5.0182,085,438 - 2,085,555 (+)NCBI
Celera181,764,854 - 1,764,971 (+)NCBI
Sequence:
Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-8405 BioCyc
Ensembl Genes ENSRNOG00000035651 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000053774 ENTREZGENE
miRBase MI0015456 ENTREZGENE
NCBI Gene 100526597 ENTREZGENE
PhenoGen Mir3582 PhenoGen
RatGTEx ENSRNOG00000035651 RatGTEx
RNAcentral URS000075A43B RNACentral
  URS000075DB86 RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-03-25 Mir3582  microRNA 3582  Mir3582  microRNA mir-3582  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-11-23 Mir3582  microRNA mir-3582      Symbol and Name status set to provisional 70820 PROVISIONAL