Mir664-2 (microRNA 664-2) - Rat Genome Database

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Pathways
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Gene: Mir664-2 (microRNA 664-2) Rattus norvegicus
Analyze
Symbol: Mir664-2
Name: microRNA 664-2
RGD ID: 2325513
Description: INTERACTS WITH bisphenol A; hexanal; paracetamol
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: rno-mir-664-2
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81399,324,650 - 99,324,708 (+)NCBIGRCr8
mRatBN7.21396,793,099 - 96,793,157 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1396,793,099 - 96,793,157 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1399,292,393 - 99,292,451 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.013100,698,199 - 100,698,257 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01397,874,647 - 97,874,705 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.013103,192,581 - 103,192,639 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13103,192,581 - 103,192,639 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013107,866,605 - 107,866,663 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1396,308,257 - 96,308,315 (+)NCBICelera
Cytogenetic Map13q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
bisphenol A  (EXP)
hexanal  (EXP)
paracetamol  (EXP)
Pirarubicin  (EXP)
rotenone  (EXP)
rutin  (EXP)
vinclozolin  (EXP)

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:16381832   PMID:16766679   PMID:20403161  


Genomics

miRNA Target Status

Confirmed Targets
Gene TargetMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mmp9rno-miR-664-3pMirtarbaseexternal_infoMicroarrayFunctional MTI (Weak)18258830

Predicted Targets
Summary Value
Count of predictions:14840
Count of gene targets:8911
Count of transcripts:9767
Interacting mature miRNAs:rno-miR-664-2-5p, rno-miR-664-3p
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131101056920Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)138897350101631289Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1320605871101339738Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1330395351101056920Rat
1641901Alcrsp6Alcohol response QTL 6response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)135236217197362171Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1356056920101056920Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1361825626106807694Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1365103704106807694Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1365103704106807694Rat
8655959Pur32Proteinuria QTL 328.4urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)137402391897213863Rat
2293341Glom15Glomerulus QTL 159.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1374862117101339893Rat
4889606Gluco63Glucose level QTL 632.860.003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1380753256106807694Rat


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NR_032143 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000071851
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1396,793,099 - 96,793,157 (+)Ensembl
Rnor_6.0 Ensembl13103,192,581 - 103,192,639 (+)Ensembl
RefSeq Acc Id: NR_032143
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81399,324,650 - 99,324,708 (+)NCBI
mRatBN7.21396,793,099 - 96,793,157 (+)NCBI
Rnor_6.013103,192,581 - 103,192,639 (+)NCBI
Rnor_5.013107,866,605 - 107,866,663 (+)NCBI
Celera1396,308,257 - 96,308,315 (+)NCBI
Sequence:
Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-16986 BioCyc
Ensembl Genes ENSRNOG00000046719 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000071851 ENTREZGENE
miRBase MI0003723 ENTREZGENE
NCBI Gene 100314092 ENTREZGENE
PhenoGen Mir664-2 PhenoGen
RatGTEx ENSRNOG00000046719 RatGTEx
RNAcentral URS000036FA83 RNACentral
  URS000075A652 RNACentral
  URS000075EC88 RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-04-09 Mir664-2  microRNA 664-2  Mir664-2  microRNA mir-664-2  Name updated 61478 APPROVED
2010-06-02 Mir664-2  microRNA mir-664-2      Symbol and Name status set to provisional 70820 PROVISIONAL