Mir1224 (microRNA 1224) - Rat Genome Database

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Gene: Mir1224 (microRNA 1224) Rattus norvegicus
Analyze
Symbol: Mir1224
Name: microRNA 1224
RGD ID: 2325484
Description: Predicted to enable mRNA base-pairing translational repressor activity. Predicted to be involved in miRNA-mediated post-transcriptional gene silencing; positive regulation of sprouting angiogenesis; and regulation of signal transduction. Predicted to act upstream of or within cellular response to amino acid stimulus; cellular response to forskolin; and cellular response to inorganic substance. Orthologous to human MIR1224 (microRNA 1224); INTERACTS WITH 2,5-hexanedione; bisphenol A; bleomycin A2.
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: rno-mir-1224
RGD Orthologs
Human
Mouse
Pig
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81193,811,291 - 93,811,375 (-)NCBIGRCr8
mRatBN7.21180,306,902 - 80,306,986 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1180,306,902 - 80,306,986 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1189,029,549 - 89,029,633 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01181,682,968 - 81,683,052 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01180,744,034 - 80,744,118 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01183,992,628 - 83,992,712 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1183,992,628 - 83,992,712 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01187,064,950 - 87,065,034 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1179,146,571 - 79,146,655 (-)NCBICelera
Cytogenetic Map11q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:16381832   PMID:18215311   PMID:20403161   PMID:20548288   PMID:21993888   PMID:33989616   PMID:36346578  


Genomics

Comparative Map Data
Mir1224
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81193,811,291 - 93,811,375 (-)NCBIGRCr8
mRatBN7.21180,306,902 - 80,306,986 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1180,306,902 - 80,306,986 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1189,029,549 - 89,029,633 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01181,682,968 - 81,683,052 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01180,744,034 - 80,744,118 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01183,992,628 - 83,992,712 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1183,992,628 - 83,992,712 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01187,064,950 - 87,065,034 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1179,146,571 - 79,146,655 (-)NCBICelera
Cytogenetic Map11q23NCBI
MIR1224
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383184,241,405 - 184,241,489 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3184,241,405 - 184,241,489 (+)EnsemblGRCh38hg38GRCh38
GRCh373183,959,193 - 183,959,277 (+)NCBIGRCh37GRCh37hg19GRCh37
Celera3182,399,957 - 182,400,041 (+)NCBICelera
Cytogenetic Map3q27.1NCBI
HuRef3181,366,162 - 181,366,246 (+)NCBIHuRef
CHM1_13183,923,615 - 183,923,699 (+)NCBICHM1_1
T2T-CHM13v2.03187,050,689 - 187,050,773 (+)NCBIT2T-CHM13v2.0
Mir1224
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391620,423,202 - 20,423,286 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1620,423,202 - 20,423,286 (+)EnsemblGRCm39 Ensembl
GRCm381620,604,452 - 20,604,536 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1620,604,452 - 20,604,536 (+)EnsemblGRCm38mm10GRCm38
Celera1621,168,528 - 21,168,612 (+)NCBICelera
Cytogenetic Map16A3NCBI
cM Map1612.48NCBI
MIR1224
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13122,141,042 - 122,141,149 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113122,141,042 - 122,141,149 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213131,580,811 - 131,580,918 (+)NCBISscrofa10.2Sscrofa10.2susScr3

miRNA Target Status

Predicted Targets
Summary Value
Count of predictions:13177
Count of gene targets:6701
Count of transcripts:7217
Interacting mature miRNAs:rno-miR-1224
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112767241082846715Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)112952841882566702Rat
1300135Rf19Renal function QTL 193.38blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)114094618882566702Rat
2312566Glom20Glomerulus QTL 203.60.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)114428575982566702Rat
1581565Pur10Proteinuria QTL 100.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)114480331882846466Rat
1581572Uae35Urinary albumin excretion QTL 350.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)114480331882846466Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)115445753486241447Rat
4889521Gluco62Glucose level QTL 622.820.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)115513672982993457Rat
7411658Foco27Food consumption QTL 2716.20.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)115635142486241447Rat
631506Bp104Blood pressure QTL 1042.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)115980279482566545Rat
70208Niddm22Non-insulin dependent diabetes mellitus QTL 223.61blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)115980279482566553Rat
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)116034659086241447Rat
1549848Bvd6Brain ventricular dilatation QTL 63.10.0001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)116611332182169223Rat
634339Niddm50Non-insulin dependent diabetes mellitus QTL 503.32blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)116642214886241447Rat
1354593Stl12Serum triglyceride level QTL 123.36blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)116642214886241447Rat
1354656Bvd3Brain ventricular dilatation QTL 33.640.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)116944607082846715Rat
10450831Scl80Serum cholesterol level QTL 804.70.01blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)117695713183051965Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

circulatory system endocrine system hemolymphoid system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium
Low 3 10 11 5 5 6 5 4 1 5
Below cutoff 2 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000063288
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1180,306,902 - 80,306,986 (-)Ensembl
Rnor_6.0 Ensembl1183,992,628 - 83,992,712 (-)Ensembl
RefSeq Acc Id: NR_032740
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81193,811,291 - 93,811,375 (-)NCBI
mRatBN7.21180,306,902 - 80,306,986 (-)NCBI
Rnor_6.01183,992,628 - 83,992,712 (-)NCBI
Rnor_5.01187,064,950 - 87,065,034 (-)NCBI
Celera1179,146,571 - 79,146,655 (-)NCBI
Sequence:
Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2325484 AgrOrtholog
BioCyc Gene G2FUF-20738 BioCyc
Ensembl Genes ENSRNOG00000041535 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000063288 ENTREZGENE
miRBase MI0012589 ENTREZGENE
NCBI Gene 100314125 ENTREZGENE
PhenoGen Mir1224 PhenoGen
RatGTEx ENSRNOG00000041535 RatGTEx
RNAcentral URS0000224406 RNACentral
  URS0000633B7D RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-04-09 Mir1224  microRNA 1224  Mir1224  microRNA mir-1224  Name updated 61478 APPROVED
2010-06-02 Mir1224  microRNA mir-1224      Symbol and Name status set to provisional 70820 PROVISIONAL