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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:hexane-1,6-diamine
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Accession:CHEBI:39618 term browser browse the term
Definition:A C6 alkane-alpha,omega-diamine.
Synonyms:related_synonym: 1,6-diamino-n-hexane;   1,6-diaminohexane;   1,6-hexamethylenediamine;   1,6-hexanediamine;   1,6-hexylenediamine;   Formula=C6H16N2;   H2N(CH2)6NH2;   HEX-NH2;   HMDA;   InChI=1S/C6H16N2/c7-5-3-1-2-4-6-8/h1-8H2;   InChIKey=NAQMVNRVTILPCV-UHFFFAOYSA-N;   SMILES=NCCCCCCN;   diaminohexane;   hexamethylene diamine;   hexamethylenediamine;   hexylenediamine
 xref: Beilstein:1098307;   CAS:124-09-4;   DrugBank:DB03260;   Gmelin:2578
 xref_mesh: MESH:C007297
 xref: PDBeChem:16D;   PMID:21527495;   PMID:22986425;   PMID:23530439;   PMID:23933844;   PMID:24064415;   PMID:6182245;   Reaxys:1098307;   Wikipedia:Hexamethylenediamine


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hexane-1,6-diamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adgrl3 adhesion G protein-coupled receptor L3 increases abundance ISO ADGRL3 gene modified form results in increased abundance of 1,6-diaminohexane CTD PMID:25445006 NCBI chr14:26,336,320...27,104,060
Ensembl chr14:26,368,277...27,105,860 		JBrowse link
G Mpo myeloperoxidase multiple interactions ISO [1,6-diaminohexane binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; [1,6-diaminohexane binds to TEMPO] inhibits the reaction [MPO protein results in increased degradation of Hydrogen Peroxide]; [1,6-diaminohexane binds to TEMPO] inhibits the reaction [MPO protein results in increased oxidation of Nitric Oxide]; Heparin inhibits the reaction [[1,6-diaminohexane binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]] CTD PMID:34085520 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Scara5 scavenger receptor class A, member 5 increases abundance ISO SCARA5 gene modified form results in increased abundance of 1,6-diaminohexane CTD PMID:25445006 NCBI chr15:39,880,017...39,985,007
Ensembl chr15:39,880,035...39,983,373 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19838
    role 19814
      application 19658
        solvent 17028
          non-polar solvent 8652
            hexane 435
              hexane-1,6-diamine 3
                N(1),N(6)-bis-DNCP-1,6-hexanediamine 0
                N-(2,4-dinitro-6-carboxy)phenyl-1.6-diaminohexane 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19838
    subatomic particle 19836
      composite particle 19836
        hadron 19836
          baryon 19836
            nucleon 19836
              atomic nucleus 19836
                atom 19836
                  main group element atom 19786
                    main group molecular entity 19786
                      s-block molecular entity 19624
                        hydrogen molecular entity 19611
                          hydrides 19117
                            inorganic hydride 18115
                              pnictogen hydride 18104
                                nitrogen hydride 18011
                                  azane 17821
                                    ammonia 17820
                                      organic amino compound 17820
                                        polyamine 9026
                                          diamine 8961
                                            primary diamine 5706
                                              alkane-alpha,omega-diamine 3783
                                                hexane-1,6-diamine 3
                                                  N(1),N(6)-bis-DNCP-1,6-hexanediamine 0
                                                  N-(2,4-dinitro-6-carboxy)phenyl-1.6-diaminohexane 0
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