Fcer1g (Fc epsilon receptor Ig) - Rat Genome Database

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Gene: Fcer1g (Fc epsilon receptor Ig) Rattus norvegicus
Analyze
Symbol: Fcer1g
Name: Fc epsilon receptor Ig
RGD ID: 2599
Description: Enables protein heterodimerization activity and protein homodimerization activity. Predicted to be involved in several processes, including antigen processing and presentation of exogenous peptide antigen via MHC class II; cell surface receptor signaling pathway; and defense response to other organism. Predicted to act upstream of or within several processes, including negative regulation of mast cell apoptotic process; positive regulation of cytokine production; and positive regulation of immune effector process. Part of Fc-gamma receptor III complex. Orthologous to human FCER1G (Fc epsilon receptor Ig); PARTICIPATES IN Fc epsilon receptor mediated signaling pathway; asthma pathway; tuberculosis pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 17beta-estradiol 3-benzoate.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Fc fragment of Ige high affinity I receptor for gamma polypeptide; Fc fragment of IgE receptor Ig; Fc fragment of IgE, high affinity I, receptor for; Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide; Fc receptor gamma-chain; Fc receptor, IgE, high affinity I, gamma polypeptide; fc-epsilon RI-gamma; fceRI gamma; fcRgamma; gamma polypeptide; high affinity immunoglobulin epsilon receptor subunit gamma; igE Fc receptor subunit gamma; MGC188226
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Candidate Gene For: Glom27
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81386,181,908 - 86,186,766 (-)NCBIGRCr8
mRatBN7.21383,649,447 - 83,654,248 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1383,649,449 - 83,671,443 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1386,155,292 - 86,160,092 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01387,553,532 - 87,558,332 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01384,785,150 - 84,789,956 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01389,601,894 - 89,606,326 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1389,601,896 - 89,606,326 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01394,228,759 - 94,233,459 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41387,119,464 - 87,123,902 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11387,308,348 - 87,312,727 (-)NCBI
Celera1383,280,630 - 83,285,062 (-)NCBICelera
Cytogenetic Map13q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,5-hexanedione  (EXP)
3,3',5,5'-tetrabromobisphenol A  (EXP)
4,4'-diaminodiphenylmethane  (EXP,ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acetylsalicylic acid  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
amphetamine  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsenous acid  (ISO)
beclomethasone  (EXP)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP,ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
chlordecone  (ISO)
choline  (ISO)
cisplatin  (EXP)
citalopram  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
Cuprizon  (EXP)
cyclophosphamide  (ISO)
D-glucose  (ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
diarsenic trioxide  (ISO)
diclofenac  (ISO)
diethylstilbestrol  (ISO)
diquat  (ISO)
diuron  (EXP)
fenbuconazole  (ISO)
folic acid  (ISO)
fulvestrant  (ISO)
ginkgolide B  (EXP)
glucose  (ISO)
ketotifen  (EXP)
L-methionine  (ISO)
lipopolysaccharide  (ISO)
mercury atom  (ISO)
mercury(0)  (ISO)
methimazole  (EXP)
methotrexate  (ISO)
methylmercury chloride  (EXP)
N-nitrosodiethylamine  (EXP)
N-nitrosodimethylamine  (EXP)
nickel atom  (ISO)
nilotinib  (ISO)
ochratoxin A  (EXP)
ozone  (EXP,ISO)
paracetamol  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
probucol  (ISO)
quercetin  (ISO)
resveratrol  (EXP)
serpentine asbestos  (ISO)
silicon dioxide  (EXP)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
streptozocin  (EXP)
tamibarotene  (ISO)
testosterone  (EXP)
testosterone enanthate  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
triphenyl phosphate  (EXP)
troglitazone  (ISO)
tungsten  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
antigen processing and presentation of exogenous peptide antigen via MHC class I  (IBA,IEA,ISO)
antigen processing and presentation of exogenous peptide antigen via MHC class II  (IBA,IEA,ISO)
cell surface receptor signaling pathway  (ISO)
cellular response to low-density lipoprotein particle stimulus  (ISO,ISS)
defense response to bacterium  (IBA,IEA,ISO)
Fc receptor mediated stimulatory signaling pathway  (IBA,IEA,ISO)
Fc-epsilon receptor signaling pathway  (IEA,ISO)
Fc-gamma receptor signaling pathway  (IBA,IEA,ISO)
immunoglobulin mediated immune response  (IBA,IEA,ISO)
innate immune response  (IBA,IEA,ISO)
integrin-mediated signaling pathway  (ISO)
interleukin-3-mediated signaling pathway  (ISO,ISS)
mast cell activation  (ISO)
mast cell apoptotic process  (ISO)
mast cell degranulation  (ISO)
negative regulation of mast cell apoptotic process  (ISO)
neutrophil activation involved in immune response  (IBA,IEA,ISO)
neutrophil chemotaxis  (IBA,IEA,ISO)
osteoclast differentiation  (ISO)
phagocytosis, engulfment  (ISO)
positive regulation of immune response  (ISO)
positive regulation of interleukin-10 production  (ISO)
positive regulation of interleukin-4 production  (ISO,ISS)
positive regulation of interleukin-6 production  (ISO)
positive regulation of mast cell cytokine production  (ISO)
positive regulation of mast cell degranulation  (ISO)
positive regulation of phagocytosis  (IBA,IEA,ISO)
positive regulation of protein localization to cell surface  (ISO)
positive regulation of tumor necrosis factor production  (ISO)
positive regulation of type I hypersensitivity  (ISO)
positive regulation of type IIa hypersensitivity  (ISO)
positive regulation of type III hypersensitivity  (ISO)
protein localization to plasma membrane  (ISO)
receptor internalization  (ISO,ISS)
regulation of immune response  (ISO)
regulation of platelet activation  (IBA,IEA,ISO)
serotonin secretion by platelet  (ISO)
signal transduction  (ISO)
T cell differentiation involved in immune response  (IBA,IEA,ISO)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Complete structure and expression in transfected cells of high affinity IgE receptor. Blank U, etal., Nature 1989 Jan 12;337(6203):187-9.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Analysis of Fc gamma RIII (CD16) membrane expression and association with CD3 zeta and Fc epsilon RI-gamma by site-directed mutation. Lanier LL, etal., J Immunol. 1991 Mar 1;146(5):1571-6.
5. Mincle, the receptor for mycobacterial cord factor, forms a functional receptor complex with MCL and FcεRI-γ. Lobato-Pascual A, etal., Eur J Immunol. 2013 Dec;43(12):3167-74. doi: 10.1002/eji.201343752. Epub 2013 Aug 26.
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
8. Online Mendelian Inheritance in Man, OMIM (TM). Online Mendelian Inheritance in Man, OMIM (TM).
9. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
10. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
11. GOA pipeline RGD automated data pipeline
12. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1535625   PMID:2527850   PMID:8976192   PMID:9000133   PMID:9171347   PMID:10229794   PMID:10395649   PMID:11237803   PMID:11420040   PMID:11901193   PMID:11911823   PMID:11911824  
PMID:12192036   PMID:12477932   PMID:14643301   PMID:14764707   PMID:14967045   PMID:15184345   PMID:15339843   PMID:16735691   PMID:17086186   PMID:17365510   PMID:17543387   PMID:19098920  
PMID:19356729   PMID:21841309   PMID:22964482   PMID:23395392   PMID:23602766   PMID:28033741   PMID:28393919  


Genomics

Comparative Map Data
Fcer1g
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81386,181,908 - 86,186,766 (-)NCBIGRCr8
mRatBN7.21383,649,447 - 83,654,248 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1383,649,449 - 83,671,443 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1386,155,292 - 86,160,092 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01387,553,532 - 87,558,332 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01384,785,150 - 84,789,956 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01389,601,894 - 89,606,326 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1389,601,896 - 89,606,326 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01394,228,759 - 94,233,459 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41387,119,464 - 87,123,902 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11387,308,348 - 87,312,727 (-)NCBI
Celera1383,280,630 - 83,285,062 (-)NCBICelera
Cytogenetic Map13q24NCBI
FCER1G
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381161,215,295 - 161,219,245 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1161,215,234 - 161,220,699 (+)EnsemblGRCh38hg38GRCh38
GRCh371161,185,085 - 161,189,035 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361159,451,711 - 159,455,662 (+)NCBINCBI36Build 36hg18NCBI36
Build 341157,998,159 - 158,002,111NCBI
Celera1134,252,239 - 134,256,190 (+)NCBICelera
Cytogenetic Map1q23.3NCBI
HuRef1132,542,035 - 132,545,988 (+)NCBIHuRef
CHM1_11162,581,340 - 162,585,295 (+)NCBICHM1_1
T2T-CHM13v2.01160,352,747 - 160,356,700 (+)NCBIT2T-CHM13v2.0
Fcer1g
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391171,057,141 - 171,061,918 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1171,057,141 - 171,061,934 (-)EnsemblGRCm39 Ensembl
GRCm381171,229,572 - 171,234,349 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1171,229,572 - 171,234,365 (-)EnsemblGRCm38mm10GRCm38
MGSCv371173,159,703 - 173,164,480 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361173,066,247 - 173,071,024 (-)NCBIMGSCv36mm8
Celera1173,677,711 - 173,690,567 (-)NCBICelera
Cytogenetic Map1H3NCBI
cM Map179.23NCBI
Fcer1g
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546812,971,931 - 12,975,206 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495546812,971,931 - 12,975,206 (+)NCBIChiLan1.0ChiLan1.0
FCER1G
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2188,632,756 - 88,636,775 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1188,323,067 - 88,327,094 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01136,627,672 - 136,631,696 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11140,539,555 - 140,543,545 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1140,539,555 - 140,544,810 (+)Ensemblpanpan1.1panPan2
FCER1G
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13821,267,841 - 21,271,036 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3821,268,001 - 21,270,940 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3821,342,857 - 21,345,796 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03821,385,844 - 21,388,784 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3821,385,844 - 21,388,784 (-)EnsemblROS_Cfam_1.0 Ensembl
UNSW_CanFamBas_1.03821,688,132 - 21,691,072 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03822,097,280 - 22,100,221 (-)NCBIUU_Cfam_GSD_1.0
Fcer1g
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244050587,305,613 - 7,309,317 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936903514,761 - 517,948 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936903514,278 - 517,975 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FCER1G
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl489,242,472 - 89,246,450 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1489,242,467 - 89,246,344 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2497,099,149 - 97,103,026 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FCER1G
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1202,763,412 - 2,767,774 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl202,763,417 - 2,767,248 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660381,811,779 - 1,815,687 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fcer1g
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624794168,564 - 172,034 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624794168,564 - 172,433 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Fcer1g
32 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:52
Count of miRNA genes:43
Interacting mature miRNAs:46
Transcripts:ENSRNOT00000029179
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131101056920Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)138897350101631289Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1320605871101339738Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1330395351101056920Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133124133193395974Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133975454484754544Rat
12879444Bp397Blood pressure QTL 397arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134504940490049404Rat
12879471Bp398Blood pressure QTL 398arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134551471990514719Rat
12879441Bp396Blood pressure QTL 396arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134569998390699983Rat
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134608804691088046Rat
71119Thym2Thymus enlargement QTL 23.8thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)134619797684753113Rat
1641901Alcrsp6Alcohol response QTL 6response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)135236217197362171Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1356056920101056920Rat
738026Lnnr5Liver neoplastic nodule remodeling QTL 53.29liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)135987440885581182Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1361825626106807694Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1365103704106807694Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1365103704106807694Rat
8655945Rf61Renal function QTL 613.6blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)136906051986800898Rat
1331783Bp221Blood pressure QTL 2213.72886arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)136906051986800898Rat
1300166Kidm6Kidney mass QTL 63.93kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)136906051986800898Rat
8655959Pur32Proteinuria QTL 328.4urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)137402391897213863Rat
738027Lnnr6Liver neoplastic nodule remodeling QTL 63.3liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)137486211785581182Rat
2293341Glom15Glomerulus QTL 159.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1374862117101339893Rat
4889606Gluco63Glucose level QTL 632.860.003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1380753256106807694Rat

Markers in Region
RH129161  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21383,649,476 - 83,649,659 (+)MAPPERmRatBN7.2
Rnor_6.01389,601,924 - 89,602,106NCBIRnor6.0
Rnor_5.01394,228,789 - 94,228,971UniSTSRnor5.0
RGSC_v3.41387,119,494 - 87,119,676UniSTSRGSC3.4
Celera1383,280,660 - 83,280,842UniSTS
RH 3.4 Map13551.5UniSTS
Cytogenetic Map13q24UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 25 48 36 19 36 2 62 34 31 11
Low 18 9 5 5 8 9 12 1 10 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000029179   ⟹   ENSRNOP00000036716
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1383,649,449 - 83,653,880 (-)Ensembl
Rnor_6.0 Ensembl1389,601,896 - 89,606,326 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000098830   ⟹   ENSRNOP00000077355
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1383,649,449 - 83,671,443 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000103864   ⟹   ENSRNOP00000096825
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1383,649,449 - 83,654,299 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000103998   ⟹   ENSRNOP00000088147
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1383,649,449 - 83,651,748 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000108934   ⟹   ENSRNOP00000089806
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1383,649,449 - 83,666,844 (-)Ensembl
RefSeq Acc Id: NM_001131001   ⟹   NP_001124473
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81386,181,908 - 86,186,323 (-)NCBI
mRatBN7.21383,649,447 - 83,653,863 (-)NCBI
Rnor_6.01389,601,894 - 89,606,326 (-)NCBI
Rnor_5.01394,228,759 - 94,233,459 (-)NCBI
RGSC_v3.41387,119,464 - 87,123,902 (-)RGD
Celera1383,280,630 - 83,285,062 (-)RGD
Sequence:
RefSeq Acc Id: NR_175264
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81386,181,908 - 86,186,708 (-)NCBI
mRatBN7.21383,649,447 - 83,654,248 (-)NCBI
RefSeq Acc Id: XM_039090390   ⟹   XP_038946318
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81386,181,908 - 86,186,710 (-)NCBI
mRatBN7.21383,649,447 - 83,654,215 (-)NCBI
RefSeq Acc Id: XM_063272045   ⟹   XP_063128115
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81386,181,908 - 86,186,606 (-)NCBI
RefSeq Acc Id: XM_063272047   ⟹   XP_063128117
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81386,182,728 - 86,186,766 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001124473   ⟸   NM_001131001
- Peptide Label: precursor
- UniProtKB: P20411 (UniProtKB/Swiss-Prot),   B1H251 (UniProtKB/TrEMBL),   A0A8I6AI77 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000036716   ⟸   ENSRNOT00000029179
RefSeq Acc Id: XP_038946318   ⟸   XM_039090390
- Peptide Label: isoform X3
- UniProtKB: A0A8I6GIE3 (UniProtKB/TrEMBL),   A0A8I6AI77 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000077355   ⟸   ENSRNOT00000098830
RefSeq Acc Id: ENSRNOP00000088147   ⟸   ENSRNOT00000103998
RefSeq Acc Id: ENSRNOP00000096825   ⟸   ENSRNOT00000103864
RefSeq Acc Id: ENSRNOP00000089806   ⟸   ENSRNOT00000108934
RefSeq Acc Id: XP_063128115   ⟸   XM_063272045
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063128117   ⟸   XM_063272047
- Peptide Label: isoform X2
Protein Domains
ITAM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P20411-F1-model_v2 AlphaFold P20411 1-86 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698997
Promoter ID:EPDNEW_R9522
Type:initiation region
Name:Fcer1g_1
Description:Fc fragment of IgE receptor Ig
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01389,606,303 - 89,606,363EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2599 AgrOrtholog
BioCyc Gene G2FUF-17382 BioCyc
Ensembl Genes ENSRNOG00000024159 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000029179.4 UniProtKB/TrEMBL
  ENSRNOT00000098830.1 UniProtKB/TrEMBL
  ENSRNOT00000103864 ENTREZGENE
  ENSRNOT00000103864.1 UniProtKB/TrEMBL
  ENSRNOT00000103998.1 UniProtKB/TrEMBL
  ENSRNOT00000108934.1 UniProtKB/TrEMBL
InterPro CD3_zeta/IgE_Fc_rcpt_gamma UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FCER1G UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Phos_immunorcpt_sig_ITAM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:25441 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 25441 ENTREZGENE
PANTHER HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR SUBUNIT GAMMA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR16803 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam ITAM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TCR_zetazeta UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Fcer1g PhenoGen
PROSITE ITAM_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000024159 RatGTEx
SMART ITAM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5YBS0_RAT UniProtKB/TrEMBL
  A0A8I6AI77 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ARQ1_RAT UniProtKB/TrEMBL
  A0A8I6GIE3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2QIN1_RAT UniProtKB/TrEMBL
  B1H251 ENTREZGENE, UniProtKB/TrEMBL
  FCERG_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-11-11 Fcer1g  Fc epsilon receptor Ig  Fcer1g  Fc fragment of IgE receptor Ig  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-01-20 Fcer1g  Fc fragment of IgE receptor Ig  Fcer1g  Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-06-15 Fcer1g  Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide  LOC498279  similar to NADH dehydrogenase (ubiquinone) Fe-S protein 2  Data merged from RGD:1594386 1643240 APPROVED
2008-09-25 Fcer1g  Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide  Fcer1g  Fc receptor, IgE, high affinity I, gamma polypeptide  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 LOC498279  similar to NADH dehydrogenase (ubiquinone) Fe-S protein 2      Symbol and Name status set to provisional 70820 PROVISIONAL
2002-06-10 Fcer1g  Fc fragment of Ige, high affinity I, receptor for gamma polypeptide      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_physical_interaction tetrameric complex composed of one alpha subunit, one beta subunit and a dimer of disulphide-linked gamma subunits 728449