Gene: Pde4a (phosphodiesterase 4A, cAMP-specific)  Rattus norvegicus

Symbol: Pde4a
Name: phosphodiesterase 4A, cAMP-specific
Description: ENCODES a protein that exhibits 3',5'-cyclic-AMP phosphodiesterase activity; INVOLVED IN cAMP catabolic process; response to drug; cellular response to drug (ortholog); PARTICIPATES IN protein kinase A (PKA) signaling pathway; purine metabolic pathway; ASSOCIATED WITH Brucellosis; Seizures; FOUND IN cytoplasm; nucleus; perinuclear region of cytoplasm; INTERACTS WITH 3H-1,2-dithiole-3-thione; ammonium chloride; clozapine
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: cAMP-specific 3',5'-cyclic phosphodiesterase 4A; DPDE2; PHOSA; phosphodiesterase 4A; phosphodiesterase 4A, cAMP specific; phosphodiesterase 4A, cAMP-specific (phosphodiesterase E2 dunce homolog, Drosophila)
Orthologs: Homo sapiens : PDE4A (phosphodiesterase 4A, cAMP-specific)  HGNC
Mus musculus : Pde4a (phosphodiesterase 4A, cAMP specific)  MGI
Allele / Splice: Pde4a_v1   Pde4a_v3   Pde4a_v2  
Latest Assembly: RGSC Genome Assembly v3.4
NCBI Annotation Information: Annotation category: suggests misassembly; Annotation category: partial on reference assembly
Position:
MapChrPositionStrandSource
Rat Cytogenetic Map8q13 NCBI
RGSC Genome Assembly v5.0822,245,707 - 22,289,417+NCBI
RGSC Genome Assembly v3.4820,192,677 - 20,241,557+NCBI
Rat Celera Assembly821,100,973 - 21,145,549+NCBI
Genome Assembly 3.1820,192,676 - 20,241,557+NCBI
Model

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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v3.4)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on Pde4a
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Ensembl Gene
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RGD Object Information
RGD ID: 3279
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2013-04-16
Status: ACTIVE