Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:increased hematopoietic stem cell number
go back to main search page
Accession:MP:0004809 term browser browse the term
Definition:greater cell count of the multipotent, self-renewing stem cells found in the bone marrow, yolk sac and the fetal liver; HSCs give rise to all the types of both the myeloid and lymphoid cell lineages
Synonyms:exact_synonym: increased HSCs;   increased haematopoietic progenitor cell number;   increased haematopoietic stem cell number;   increased haemopoietic progenitor cell number;   increased hematopoietic progenitor cell number;   increased hemopoietic progenitor cell number;   increased number of hematopoietic stem cells
 narrow_synonym: increased LSK cell number


show annotations for term's descendants           Sort by:
increased hematopoietic stem cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP-binding cassette, sub-family A member 1 IAGP MGI PMID:22862945 NCBI chr 4:53,030,789...53,159,988
Ensembl chr 4:53,030,787...53,159,895 		JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 IAGP MGI PMID:22862945 NCBI chr17:31,276,668...31,336,958
Ensembl chr17:31,276,649...31,336,962 		JBrowse link
G Adam10 a disintegrin and metallopeptidase domain 10 IAGP MGI PMID:22042698 NCBI chr 9:70,586,133...70,687,511
Ensembl chr 9:70,586,279...70,687,511 		JBrowse link
G Ang angiogenin, ribonuclease, RNase A family, 5 IAGP MGI PMID:27518564 NCBI chr14:51,328,607...51,339,462
Ensembl chr14:51,328,607...51,339,466 		JBrowse link
G Arid1a AT-rich interaction domain 1A IAGP MGI PMID:20522713 NCBI chr 4:133,406,319...133,484,682
Ensembl chr 4:133,406,319...133,484,080 		JBrowse link
G Arid4a AT-rich interaction domain 4A IAGP MGI PMID:18728284 NCBI chr12:71,061,314...71,146,125
Ensembl chr12:71,062,764...71,145,366 		JBrowse link
G Arid4b AT-rich interaction domain 4B IAGP MGI PMID:18728284 NCBI chr13:14,238,334...14,374,188
Ensembl chr13:14,237,817...14,374,188 		JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 IAGP MGI PMID:29908121 NCBI chr 8:41,793,683...41,850,681
Ensembl chr 8:41,793,234...41,827,810 		JBrowse link
G Asxl1 ASXL transcriptional regulator 1 IAGP MGI PMID:24218140 PMID:24255920 NCBI chr 2:153,187,750...153,245,927
Ensembl chr 2:153,187,749...153,245,927 		JBrowse link
G Babam1 BRISC and BRCA1 A complex member 1 IAGP MGI PMID:25636339 NCBI chr 8:71,848,809...71,857,416
Ensembl chr 8:71,849,505...71,857,263 		JBrowse link
G Bap1 Brca1 associated protein 1 IAGP MGI PMID:22878500 NCBI chr14:30,973,358...30,981,887
Ensembl chr14:30,973,407...30,981,901 		JBrowse link
G Bloc1s2 biogenesis of lysosomal organelles complex-1, subunit 2 IAGP MGI PMID:27719760 NCBI chr19:44,127,685...44,134,909
Ensembl chr19:44,127,685...44,134,885 		JBrowse link
G Cbfb core binding factor beta IAGP MGI PMID:12434155 PMID:16413472 NCBI chr 8:105,897,306...105,944,621
Ensembl chr 8:105,897,306...105,944,621 		JBrowse link
G Cbl Casitas B-lineage lymphoma IAGP MGI PMID:19620960 NCBI chr 9:44,054,273...44,145,556
Ensembl chr 9:44,054,273...44,145,346 		JBrowse link
G Cdk19 cyclin dependent kinase 19 IAGP MGI PMID:35110726 NCBI chr10:40,225,283...40,359,814
Ensembl chr10:40,215,560...40,359,814 		JBrowse link
G Cdk6 cyclin dependent kinase 6 IAGP MGI PMID:21508411 NCBI chr 5:3,391,004...3,581,008
Ensembl chr 5:3,391,485...3,581,008 		JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A IAGP MGI PMID:10710306 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701 		JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha IAGP MGI PMID:22715416 NCBI chr 7:34,818,718...34,821,353
Ensembl chr 7:34,818,718...34,821,353 		JBrowse link
G Commd10 COMM domain containing 10 IAGP MGI PMID:22422825 PMID:22763442 PMID:30952670 PMID:33753942 NCBI chr18:47,091,917...47,242,435
Ensembl chr18:47,091,883...47,367,351 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 IAGP MGI PMID:20833981 NCBI chr 6:117,145,496...117,158,329
Ensembl chr 6:117,145,496...117,158,328 		JBrowse link
G Dhx36 DEAH-box helicase 36 IAGP MGI PMID:22422825 NCBI chr 3:62,375,436...62,414,464
Ensembl chr 3:62,375,434...62,414,425 		JBrowse link
G Dnmt3a DNA methyltransferase 3A IAGP MGI PMID:30692594 NCBI chr12:3,851,559...3,964,442
Ensembl chr12:3,856,007...3,964,443 		JBrowse link
G Dppa3 developmental pluripotency-associated 3 IAGP MGI PMID:26692333 NCBI chr 6:122,603,383...122,607,230
Ensembl chr 6:122,603,369...122,607,231 		JBrowse link
G Elf4 E74 like ETS transcription factor 4 IAGP MGI PMID:16530702 NCBI chr  X:47,499,926...47,552,009
Ensembl chr  X:47,499,923...47,552,009 		JBrowse link
G Etv6 ets variant 6 IAGP MGI PMID:19570513 NCBI chr 6:134,012,663...134,247,121
Ensembl chr 6:134,012,663...134,247,121 		JBrowse link
G Flt3 FMS-like tyrosine kinase 3 IAGP MGI PMID:18245664 NCBI chr 5:147,267,551...147,337,299
Ensembl chr 5:147,267,551...147,337,299 		JBrowse link
G Gfi1 growth factor independent 1 transcription repressor IAGP MGI PMID:22932805 NCBI chr 5:107,864,521...107,873,671
Ensembl chr 5:107,864,523...107,873,902 		JBrowse link
G Gfi1b growth factor independent 1B IAGP MGI PMID:20826720 NCBI chr 2:28,499,462...28,511,994
Ensembl chr 2:28,499,462...28,511,994 		JBrowse link
G Gimap5 GTPase, IMAP family member 5 IAGP MGI PMID:20190135 NCBI chr 6:48,723,131...48,731,134
Ensembl chr 6:48,723,131...48,731,144 		JBrowse link
G Gmnn geminin IAGP MGI PMID:21041951 NCBI chr13:24,935,828...24,954,222
Ensembl chr13:24,935,828...24,945,906 		JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:16980619 PMID:20010698 PMID:20616797 PMID:22606246 PMID:22699452 More... NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,054,294 		JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit IAGP MGI PMID:22995899 NCBI chr12:73,948,186...73,994,304
Ensembl chr12:73,948,149...73,994,304 		JBrowse link
G Hip1 huntingtin interacting protein 1 IAGP MGI PMID:19647224 NCBI chr 5:135,435,350...135,574,167
Ensembl chr 5:135,435,385...135,573,974 		JBrowse link
G Hoxa9 homeobox A9 IAGP MGI PMID:17761289 NCBI chr 6:52,200,077...52,203,169
Ensembl chr 6:52,200,080...52,208,069 		JBrowse link
G Idh1 isocitrate dehydrogenase 1 (NADP+), soluble IAGP MGI PMID:22763442 NCBI chr 1:65,197,775...65,225,638
Ensembl chr 1:65,197,775...65,225,659 		JBrowse link
G Ifng interferon gamma IAGP MGI PMID:25342713 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797 		JBrowse link
G Il2ra interleukin 2 receptor, alpha chain IAGP MGI PMID:21508411 NCBI chr 2:11,647,603...11,698,005
Ensembl chr 2:11,647,618...11,698,004 		JBrowse link
G Itga2b integrin alpha 2b IAGP MGI PMID:12871637 NCBI chr11:102,344,134...102,360,570
Ensembl chr11:102,344,123...102,360,948 		JBrowse link
G Jak2 Janus kinase 2 IAGP MGI PMID:22144185 PMID:23863895 PMID:26692333 NCBI chr19:29,229,006...29,290,495
Ensembl chr19:29,229,228...29,290,480 		JBrowse link
G Kdm1a lysine (K)-specific demethylase 1A IAGP MGI PMID:23795291 NCBI chr 4:136,277,844...136,330,127
Ensembl chr 4:136,277,851...136,330,034 		JBrowse link
G Kdm6a lysine (K)-specific demethylase 6A IAGP MGI PMID:29479066 NCBI chr  X:18,027,101...18,147,061
Ensembl chr  X:18,028,814...18,146,175 		JBrowse link
G Kmt2e lysine (K)-specific methyltransferase 2E IAGP MGI PMID:18818388 NCBI chr 5:23,638,034...23,709,233
Ensembl chr 5:23,639,439...23,709,233 		JBrowse link
G Kras Kirsten rat sarcoma viral oncogene homolog IAGP MGI PMID:25359213 NCBI chr 6:145,162,425...145,197,631
Ensembl chr 6:145,162,425...145,195,965 		JBrowse link
G Lyz2 lysozyme 2 IAGP MGI PMID:22763442 NCBI chr10:117,113,446...117,118,177
Ensembl chr10:117,113,236...117,118,226 		JBrowse link
G Man2a1 mannosidase 2, alpha 1 IAGP MGI PMID:9230311 NCBI chr17:64,907,683...65,062,105
Ensembl chr17:64,907,731...65,062,105 		JBrowse link
G Matk megakaryocyte-associated tyrosine kinase IAGP MGI PMID:16574955 NCBI chr10:81,088,769...81,098,819
Ensembl chr10:81,088,769...81,099,199 		JBrowse link
G Mcm3 minichromosome maintenance complex component 3 IAGP MGI PMID:26456157 NCBI chr 1:20,873,188...20,890,536
Ensembl chr 1:20,873,192...20,890,536 		JBrowse link
G Meis1 Meis homeobox 1 IAGP MGI PMID:22995899 NCBI chr11:18,830,428...18,968,992
Ensembl chr11:18,829,817...18,968,985 		JBrowse link
G Meox2 mesenchyme homeobox 2 IAGP MGI PMID:33681212 NCBI chr12:37,158,539...37,229,533
Ensembl chr12:37,158,539...37,229,533 		JBrowse link
G Ncstn nicastrin IAGP MGI PMID:21562564 NCBI chr 1:171,893,580...171,910,356
Ensembl chr 1:171,893,580...171,910,362 		JBrowse link
G Npm1 nucleophosmin 1 IAGP MGI PMID:21979879 PMID:23226219 NCBI chr11:33,102,498...33,114,143
Ensembl chr11:33,102,287...33,113,206 		JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 IAGP MGI PMID:17515897 NCBI chr15:101,151,783...101,172,676
Ensembl chr15:101,152,150...101,172,676 		JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 IAGP MGI PMID:17515897 NCBI chr 4:48,045,098...48,086,446
Ensembl chr 4:48,045,153...48,086,447 		JBrowse link
G Nras neuroblastoma ras oncogene IAGP MGI PMID:33681212 NCBI chr 3:102,965,643...102,975,230
Ensembl chr 3:102,965,601...102,975,230 		JBrowse link
G Ociad1 OCIA domain containing 1 IAGP MGI PMID:30952670 NCBI chr 5:73,450,093...73,471,420
Ensembl chr 5:73,450,127...73,471,412 		JBrowse link
G Pclaf PCNA clamp associated factor IAGP MGI PMID:21844206 NCBI chr 9:65,797,605...65,810,833
Ensembl chr 9:65,797,519...65,810,548 		JBrowse link
G Per2 period circadian clock 2 IAGP MGI PMID:23193187 NCBI chr 1:91,343,699...91,387,028
Ensembl chr 1:91,343,704...91,387,046 		JBrowse link
G Pfkm phosphofructokinase, muscle IAGP MGI PMID:19696889 NCBI chr15:97,990,470...98,030,328
Ensembl chr15:97,990,470...98,030,332 		JBrowse link
G Phf6 PHD finger protein 6 IAGP MGI PMID:30755422 PMID:31395598 NCBI chr  X:52,001,091...52,045,838
Ensembl chr  X:52,001,143...52,045,820 		JBrowse link
G Pml promyelocytic leukemia IAGP MGI PMID:29191918 NCBI chr 9:58,125,359...58,157,077
Ensembl chr 9:58,125,359...58,157,069 		JBrowse link
G Pole4 polymerase (DNA-directed), epsilon 4 (p12 subunit) IAGP MGI PMID:29754823 NCBI chr 6:82,593,513...82,629,985
Ensembl chr 6:82,595,973...82,682,346 		JBrowse link
G Ppp2ca protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform IAGP MGI PMID:21514445 NCBI chr11:51,989,651...52,013,576
Ensembl chr11:51,989,508...52,018,605 		JBrowse link
G Ptpmt1 protein tyrosine phosphatase, mitochondrial 1 IAGP MGI PMID:23290137 NCBI chr 2:90,741,057...90,748,395
Ensembl chr 2:90,739,060...90,748,389 		JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 IAGP MGI PMID:21930766 NCBI chr 5:121,268,596...121,329,460
Ensembl chr 5:121,268,596...121,329,460 		JBrowse link
G Rbm15 RNA binding motif protein 15 IAGP MGI PMID:17376872 PMID:19287095 PMID:19542301 NCBI chr 3:107,212,827...107,244,102
Ensembl chr 3:107,232,737...107,240,989 		JBrowse link
G Riok2 RIO kinase 2 IAGP MGI PMID:33753942 NCBI chr17:17,594,594...17,615,161
Ensembl chr17:17,594,571...17,615,161 		JBrowse link
G Runx1 runt related transcription factor 1 IAGP MGI PMID:16247465 PMID:19129762 PMID:19570513 PMID:19647224 PMID:20139099 More... NCBI chr16:92,398,354...92,622,962
Ensembl chr16:92,398,354...92,623,037 		JBrowse link
G Scmh1 sex comb on midleg homolog 1 IAGP MGI PMID:23207902 NCBI chr 4:120,262,347...120,387,397
Ensembl chr 4:120,262,478...120,387,383 		JBrowse link
G Sf3b1 splicing factor 3b, subunit 1 IAGP MGI PMID:27622333 NCBI chr 1:55,024,328...55,066,660
Ensembl chr 1:55,024,328...55,066,640 		JBrowse link
G Sipa1 signal-induced proliferation associated gene 1 IAGP MGI PMID:12892713 NCBI chr19:5,701,211...5,713,758
Ensembl chr19:5,701,213...5,713,735 		JBrowse link
G Spi1 Spi-1 proto-oncogene IAGP MGI PMID:23395001 NCBI chr 2:90,912,750...90,946,104
Ensembl chr 2:90,912,735...90,946,101 		JBrowse link
G Spp1 secreted phosphoprotein 1 IAGP MGI PMID:15845900 NCBI chr 5:104,582,977...104,588,919
Ensembl chr 5:104,582,984...104,588,916 		JBrowse link
G Srsf2 serine and arginine-rich splicing factor 2 IAGP MGI PMID:25965569 NCBI chr11:116,740,723...116,744,511
Ensembl chr11:116,740,727...116,743,920 		JBrowse link
G Stag2 STAG2 cohesin complex component IAGP MGI PMID:32249213 NCBI chr  X:41,238,172...41,366,063
Ensembl chr  X:41,238,194...41,366,062 		JBrowse link
G Stk11 serine/threonine kinase 11 IAGP MGI PMID:21124450 NCBI chr10:79,951,602...79,966,513
Ensembl chr10:79,951,637...79,966,516 		JBrowse link
G Tal1 T cell acute lymphocytic leukemia 1 IAGP MGI PMID:22401818 NCBI chr 4:114,913,623...114,928,952
Ensembl chr 4:114,913,623...114,928,952 		JBrowse link
G Tcim transcriptional and immune response regulator IAGP MGI PMID:24937306 NCBI chr 8:24,927,188...24,928,962
Ensembl chr 8:24,927,196...24,929,000 		JBrowse link
G Tet2 tet methylcytosine dioxygenase 2 IAGP MGI PMID:21723201 PMID:21803851 PMID:21873190 PMID:27622333 NCBI chr 3:133,169,438...133,250,882
Ensembl chr 3:133,169,440...133,250,900 		JBrowse link
G Trp53 transformation related protein 53 IAGP MGI PMID:21844206 PMID:23538418 PMID:29479066 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
G Vhl von Hippel-Lindau tumor suppressor IAGP MGI PMID:22464323 NCBI chr 6:113,600,955...113,608,595
Ensembl chr 6:113,600,920...113,608,594 		JBrowse link
G Wbp1l WW domain binding protein 1 like IAGP MGI PMID:31845480 NCBI chr19:46,587,545...46,645,828
Ensembl chr19:46,587,523...46,645,828 		JBrowse link
G Xist inactive X specific transcripts IAGP MGI PMID:16980619 NCBI chr  X:102,503,979...102,526,839
Ensembl chr  X:102,503,972...102,526,860 		JBrowse link
G Zbtb7a zinc finger and BTB domain containing 7a IAGP MGI PMID:17495164 NCBI chr10:80,971,113...80,988,056
Ensembl chr10:80,971,054...80,988,829 		JBrowse link
G Zfand2b zinc finger, AN1 type domain 2B IAGP MGI PMID:26692333 NCBI chr 1:75,145,290...75,148,270
Ensembl chr 1:75,145,290...75,148,273 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16879
    hematopoietic system phenotype 5514
      abnormal hematopoietic system morphology/development 5051
        abnormal hematopoietic cell morphology 4218
          abnormal hematopoietic cell number 3037
            increased hematopoietic cell number 2028
              increased hematopoietic stem cell number 84
paths to the root