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Gene: Man2a1 (mannosidase 2, alpha 1) Mus musculus
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Symbol: Man2a1
Name: mannosidase 2, alpha 1
Description: Exhibits hydrolase activity, hydrolyzing N-glycosyl compounds and mannosidase activity. Involved in several processes, including N-glycan processing; animal organ development; and respiratory gaseous exchange by respiratory system. Localizes to the Golgi membrane; cis-Golgi network; and extracellular space. Used to study congenital dyserythropoietic anemia and systemic lupus erythematosus. Is expressed in adrenal gland; gland; and white fat. Orthologous to human MAN2A1 (mannosidase alpha class 2A member 1); PARTICIPATES IN N-linked glycan biosynthetic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4'-tetrachlorobiphenyl; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: alpha-mannosidase 2; AMan II; golgi alpha-mannosidase II; man II; Mana-2; Mana2; mannosidase alpha class 2A member 1; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase; Map-2
Orthologs:
Homo sapiens (human) : MAN2A1 (mannosidase alpha class 2A member 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Man2a1 (mannosidase, alpha, class 2A, member 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Man2a1 (mannosidase alpha class 2A member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MAN2A1 (mannosidase alpha class 2A member 1)
Canis lupus familiaris (dog) : MAN2A1 (mannosidase alpha class 2A member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Man2a1 (mannosidase alpha class 2A member 1)
Sus scrofa (pig) : MAN2A1 (mannosidase alpha class 2A member 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1764,600,736 - 64,755,110 (+)Ensembl
GRCm381764,600,688 - 64,755,110 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371764,950,989 - 65,104,450 (+)NCBIGRCm37mm9NCBIm37
MGSCv361764,497,940 - 64,651,401 (+)NCBImm8
Celera1768,918,943 - 69,071,751 (+)NCBICelera
Cytogenetic Map17 E1.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Man2a1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735706
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.