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Gene: Cdk6 (cyclin-dependent kinase 6) Mus musculus
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Symbol: Cdk6
Name: cyclin-dependent kinase 6
Description: Exhibits kinase activity. Involved in several processes, including hemopoiesis; regulation of gene expression; and regulation of hematopoietic stem cell differentiation. Localizes to the cyclin D2-CDK6 complex. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma; malignant glioma; pancreatic adenocarcinoma; pancreatic ductal carcinoma; and primary autosomal recessive microcephaly 12. Is expressed in several structures, including branchial arch; central nervous system; forelimb bud; incisor; and sensory organ. Orthologous to human CDK6 (cyclin dependent kinase 6).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 5830411I20; AI504062; cell division protein kinase 6; CR2 protein kinase; Crk2; serine/threonine-protein kinase PLSTIRE
Orthologs:
Homo sapiens (human) : CDK6 (cyclin dependent kinase 6)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cdk6 (cyclin-dependent kinase 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cdk6 (cyclin dependent kinase 6)
Pan paniscus (bonobo/pygmy chimpanzee) : CDK6 (cyclin dependent kinase 6)
Canis lupus familiaris (dog) : CDK6 (cyclin dependent kinase 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cdk6 (cyclin dependent kinase 6)
Sus scrofa (pig) : CDK6 (cyclin dependent kinase 6)
more info ...
Related Pseudogenes: Gm11786  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3853,341,004 - 3,531,008 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3753,344,312 - 3,522,225 (+)NCBIGRCm37mm9NCBIm37
MGSCv3653,350,318 - 3,528,231 (+)NCBImm8
Celera53,279,311 - 3,457,786 (+)NCBICelera
Cytogenetic Map5 A1NCBI
cM Map52.04NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Cdk6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735401
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.