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Gene: Cdk6 (cyclin-dependent kinase 6) Mus musculus
Symbol: Cdk6
Name: cyclin-dependent kinase 6
Description: Exhibits kinase activity. Involved in several processes, including hemopoiesis; regulation of gene expression; and regulation of hematopoietic stem cell differentiation. Localizes to the cyclin D2-CDK6 complex. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma; malignant glioma; pancreatic adenocarcinoma; pancreatic ductal carcinoma; and primary autosomal recessive microcephaly 12. Is expressed in several structures, including branchial arch; central nervous system; forelimb bud; incisor; and sensory organ. Orthologous to human CDK6 (cyclin dependent kinase 6).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 5830411I20; AI504062; cell division protein kinase 6; CR2 protein kinase; Crk2; serine/threonine-protein kinase PLSTIRE
Homo sapiens (human) : CDK6 (cyclin dependent kinase 6)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cdk6 (cyclin-dependent kinase 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cdk6 (cyclin dependent kinase 6)
Pan paniscus (bonobo/pygmy chimpanzee) : CDK6 (cyclin dependent kinase 6)
Canis lupus familiaris (dog) : CDK6 (cyclin dependent kinase 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cdk6 (cyclin dependent kinase 6)
Sus scrofa (pig) : CDK6 (cyclin dependent kinase 6)
more info ...
Related Pseudogenes: Gm11786  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm3853,341,004 - 3,531,008 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3753,344,312 - 3,522,225 (+)NCBIGRCm37mm9NCBIm37
MGSCv3653,350,318 - 3,528,231 (+)NCBImm8
Celera53,279,311 - 3,457,786 (+)NCBICelera
Cytogenetic Map5 A1NCBI
cM Map52.04NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Cdk6
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735401
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.