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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of triglyceride metabolic process
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Accession:GO:0090207 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving triglyceride, any triester of glycerol.


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regulation of triglyceride metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E IDA RGD PMID:9225228 RGD:10059686 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Atg14 autophagy related 14 acts_upstream_of_or_within ISO (MGI:5467161|PMID:22992773) RGD PMID:22992773 MGI:5467161 NCBI chr15:24,343,418...24,374,776
Ensembl chr15:24,343,314...24,374,753
JBrowse link
G Gnb3 G protein subunit beta 3 involved_in ISO UniProtKB:Q61011 (PMID:29206867) RGD PMID:29206867 NCBI chr 4:157,352,558...157,359,237
Ensembl chr 4:157,352,372...157,358,262
JBrowse link
G Lmf1 lipase maturation factor 1 acts_upstream_of_or_within ISO MGI:1856820 (MGI:3771138|PMID:17994020), (MGI:55554|PMID:6857276) RGD PMID:6857276 PMID:17994020 MGI:3771138 MGI:55554 NCBI chr10:14,945,185...15,031,855
Ensembl chr10:14,945,265...15,031,942
JBrowse link
G Mboat7 membrane bound O-acyltransferase domain containing 7 involved_in ISO (PMID:32253259)
(MGI:6467705|PMID:32253259)
RGD PMID:32253259 MGI:6467705 NCBI chr 1:64,100,159...64,114,437
Ensembl chr 1:64,101,018...64,113,792
JBrowse link
G Pank2 pantothenate kinase 2 involved_in ISO (PMID:22221393) RGD PMID:22221393 NCBI chr 3:123,807,911...123,841,797
Ensembl chr 3:123,807,952...123,841,797
JBrowse link
G Serpina12 serpin family A member 12 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:5568548 (MGI:5563627|PMID:22837305)
Ensembl
RGD
PMID:22837305 GO_REF:0000107 MGI:5563627 NCBI chr 6:127,696,501...127,711,238
Ensembl chr 6:127,696,252...127,711,212
JBrowse link
G Tbl1xr1 TBL1X receptor 1 acts_upstream_of_or_within ISO MGI:5511131 (MGI:5495568|PMID:23499424) RGD PMID:23499424 MGI:5495568 NCBI chr 2:107,221,913...107,359,229
Ensembl chr 2:107,233,054...107,359,229
JBrowse link
G Thrb thyroid hormone receptor beta IMP RGD PMID:17878314 RGD:2315101 NCBI chr15:8,890,578...9,239,815
Ensembl chr15:8,890,578...9,086,282
JBrowse link
negative regulation of phosphatidate phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lpin1 lipin 1 IMP RGD PMID:21715287 RGD:38599010 NCBI chr 6:41,796,214...41,905,149
Ensembl chr 6:41,799,749...41,870,046
JBrowse link
negative regulation of triglyceride biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 IMP RGD PMID:29148806 RGD:15042869 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link
G Sik1 salt-inducible kinase 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:5294536|PMID:19244231)
UniProt
RGD
PMID:19244231 GO_REF:0000024 MGI:5294536 NCBI chr20:10,670,747...10,680,279
Ensembl chr20:10,668,411...10,680,283
JBrowse link
negative regulation of triglyceride catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoc3 apolipoprotein C3 involved_in ISO
IEA
IBA
(PMID:18635818), (PMID:3973011)
GO_REF:0000107
PMID:21873635
RGD
Ensembl
PMID:3973011 PMID:18635818, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 8:50,529,318...50,531,498
Ensembl chr 8:50,529,318...50,531,498
JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 involved_in ISS
ISO
GO_REF:0000024
(MGI:3617276|PMID:16219662)
UniProt
RGD
PMID:16219662 GO_REF:0000024 MGI:3617276 NCBI chr17:42,085,027...42,131,344
Ensembl chr17:42,085,028...42,127,678
JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma IMP RGD PMID:21435395 RGD:6482711 NCBI chr 6:51,465,696...51,501,234
Ensembl chr 6:51,465,908...51,498,337
JBrowse link
G Plin5 perilipin 5 involved_in ISS
ISO
GO_REF:0000024
(MGI:5476606|PMID:23345411), (MGI:5559662|PMID:22675471)
UniProt
RGD
PMID:22675471 PMID:23345411 GO_REF:0000024 MGI:5476606 MGI:5559662 NCBI chr 9:10,956,013...10,961,782
Ensembl chr 9:10,956,056...10,961,782
JBrowse link
G Sorl1 sortilin related receptor 1 involved_in ISO (MGI:5811185|PMID:27322061) RGD PMID:27322061 MGI:5811185 NCBI chr 8:46,228,077...46,287,171 JBrowse link
negative regulation of triglyceride metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apobec1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 acts_upstream_of_or_within ISO MGI:88057 (MGI:894899|PMID:9240444) RGD PMID:9240444 MGI:894899 NCBI chr 4:155,386,367...155,414,034
Ensembl chr 4:155,386,711...155,401,480
JBrowse link
G Apoe apolipoprotein E acts_upstream_of_or_within ISO MGI:103298 (MGI:894899|PMID:9240444) RGD PMID:9240444 MGI:894899 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Ccnc cyclin C IMP RGD PMID:22684109 RGD:9590256 NCBI chr 5:35,865,598...35,883,732
Ensembl chr 5:35,865,605...35,883,706
JBrowse link
G Cdk8 cyclin-dependent kinase 8 IMP RGD PMID:22684109 RGD:9590256 NCBI chr12:10,496,273...10,561,335 JBrowse link
G Esr1 estrogen receptor 1 IDA RGD PMID:23871901 RGD:8552990 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
positive regulation of triglyceride biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsl5 acyl-CoA synthetase long-chain family member 5 IDA RGD PMID:16263710 RGD:2312807 NCBI chr 1:276,240,703...276,290,012
Ensembl chr 1:276,240,703...276,290,008
JBrowse link
G Apoc3 apolipoprotein C3 IMP RGD PMID:23542898 RGD:10054091 NCBI chr 8:50,529,318...50,531,498
Ensembl chr 8:50,529,318...50,531,498
JBrowse link
G Cnep1r1 CTD nuclear envelope phosphatase 1 regulatory subunit 1 involved_in ISO (PMID:22134922) RGD PMID:22134922 NCBI chr19:19,899,306...19,913,605
Ensembl chr19:19,899,306...19,913,605
JBrowse link
G Ctdnep1 CTD nuclear envelope phosphatase 1 involved_in ISO
ISS
(PMID:22134922)
GO_REF:0000024
RGD
UniProt
PMID:22134922 GO_REF:0000024 NCBI chr10:56,590,822...56,600,235
Ensembl chr10:56,591,292...56,600,232
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 IMP RGD PMID:23449193 RGD:10400846 NCBI chr 7:117,566,363...117,576,735
Ensembl chr 7:117,566,368...117,576,737
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 IMP RGD PMID:17526931 RGD:10400884 NCBI chr 1:164,113,459...164,143,818
Ensembl chr 1:164,113,459...164,143,818
JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial IDA RGD PMID:15598672 RGD:2313665 NCBI chr 1:275,843,823...275,906,880
Ensembl chr 1:275,846,819...275,906,686
JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 involved_in ISS
ISO
GO_REF:0000024
(MGI:3617276|PMID:16219662)
UniProt
RGD
PMID:16219662 GO_REF:0000024 MGI:3617276 NCBI chr17:42,085,027...42,131,344
Ensembl chr17:42,085,028...42,127,678
JBrowse link
G Ldlr low density lipoprotein receptor involved_in IEA
ISO
GO_REF:0000107
(MGI:3784112|PMID:18175806)
Ensembl
RGD
PMID:18175806 GO_REF:0000107 MGI:3784112 NCBI chr 8:22,750,425...22,773,305
Ensembl chr 8:22,750,336...22,774,903
JBrowse link
G Mfsd2a major facilitator superfamily domain containing 2A acts_upstream_of_or_within ISO (MGI:5474727|PMID:23209793) RGD PMID:23209793 MGI:5474727 NCBI chr 5:140,642,865...140,657,759
Ensembl chr 5:140,642,885...140,657,745
JBrowse link
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 involved_in ISO (PMID:17186944) RGD PMID:17186944 NCBI chr 1:100,554,577...100,559,896
Ensembl chr 1:100,554,544...100,559,942
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 involved_in ISO
IEA
(PMID:17693624)
GO_REF:0000107
RGD
Ensembl
PMID:17693624 GO_REF:0000107 NCBI chr 3:80,004,130...80,014,197
Ensembl chr 3:80,004,130...80,012,750
JBrowse link
G Plin5 perilipin 5 involved_in ISS
ISO
GO_REF:0000024
(MGI:3709110|PMID:17130488), (MGI:5440401|PMID:22532565), (MGI:5559666|PMID:21885430)
UniProt
RGD
PMID:17130488 PMID:21885430 PMID:22532565 GO_REF:0000024 MGI:3709110 MGI:5440401 MGI:5559666 NCBI chr 9:10,956,013...10,961,782
Ensembl chr 9:10,956,056...10,961,782
JBrowse link
G Rgn regucalcin IDA RGD PMID:16817230 RGD:9590221 NCBI chr  X:1,833,484...1,848,904
Ensembl chr  X:1,833,492...1,848,904
JBrowse link
G Scarb1 scavenger receptor class B, member 1 involved_in ISO (MGI:3784112|PMID:18175806) RGD PMID:18175806 MGI:3784112 NCBI chr12:36,694,952...36,761,445
Ensembl chr12:36,694,960...36,761,455
JBrowse link
G Slc27a1 solute carrier family 27 member 1 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:6154651|PMID:12235169)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:12235169 GO_REF:0000024 GO_REF:0000107 MGI:6154651 NCBI chr16:19,997,823...20,016,193
Ensembl chr16:19,999,112...20,016,190
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
MGI:2177959 (MGI:3603730|PMID:16046411)
(MGI:5294536|PMID:19244231)
UniProt
RGD
PMID:16046411 PMID:19244231 GO_REF:0000024 MGI:3603730 MGI:5294536 NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009
JBrowse link
G Tcf7l2 transcription factor 7 like 2 acts_upstream_of_or_within ISO MGI:1926344 (MGI:5468191|PMID:23260145) RGD PMID:23260145 MGI:5468191 NCBI chr 1:276,686,911...276,730,517
Ensembl chr 1:276,659,542...276,730,514
Ensembl chr 1:276,659,542...276,730,514
JBrowse link
positive regulation of triglyceride catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aadac arylacetamide deacetylase involved_in IEA
ISO
IBA
GO_REF:0000107
(MGI:4430797|PMID:19654421)
PMID:21873635
Ensembl
RGD
PMID:19654421, PMID:21873635 GO_REF:0000107 MGI:4430797, RGD:13792537 NCBI chr 2:150,146,234...150,157,480
Ensembl chr 2:150,146,234...150,157,480
JBrowse link
G Abhd5 abhydrolase domain containing 5, lysophosphatidic acid acyltransferase involved_in ISS
ISO
IBA
GO_REF:0000024
(MGI:3769941|PMID:16679289)
PMID:21873635
(PMID:16679289)
UniProt
RGD
PMID:16679289, PMID:21873635 GO_REF:0000024 MGI:3769941, RGD:13792537 NCBI chr 8:130,973,222...131,001,448
Ensembl chr 8:130,973,201...131,001,458
JBrowse link
G Apoa1 apolipoprotein A1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Apoa4 apolipoprotein A4 involved_in IBA
IEA
ISO
PMID:21873635
GO_REF:0000107
(PMID:2307668)
Ensembl
RGD
PMID:2307668, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 8:50,536,983...50,539,371
Ensembl chr 8:50,537,009...50,539,376
JBrowse link
G Apoa5 apolipoprotein A5 involved_in ISO
IEA
IBA
(PMID:18635818)
GO_REF:0000107
PMID:21873635
RGD
Ensembl
PMID:18635818, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 8:50,559,079...50,561,720
Ensembl chr 8:50,559,126...50,561,736
JBrowse link
G Apoc2 apolipoprotein C2 involved_in ISO (PMID:10727238) RGD PMID:10727238 NCBI chr 1:80,589,023...80,593,991
Ensembl chr 1:80,589,023...80,594,136
JBrowse link
G Apoh apolipoprotein H IDA RGD PMID:7078428 RGD:8554677 NCBI chr10:96,640,013...96,653,939
Ensembl chr10:96,639,924...96,653,938
JBrowse link
G Daglb diacylglycerol lipase, beta involved_in ISS
ISO
IEA
PMID:31991095
(MGI:6415524|PMID:31991095)
GO_REF:0000107
RGD
Ensembl
PMID:31991095, PMID:31991095 GO_REF:0000107 MGI:6415524, RGD:25671402 NCBI chr12:13,113,073...13,157,748
Ensembl chr12:13,113,237...13,157,666
JBrowse link
G Fgf21 fibroblast growth factor 21 IMP RGD PMID:23262585 RGD:10401916 NCBI chr 1:101,595,579...101,596,822
Ensembl chr 1:101,595,579...101,596,822
JBrowse link
G Ldlr low density lipoprotein receptor IMP RGD PMID:28469073 RGD:12910100 NCBI chr 8:22,750,425...22,773,305
Ensembl chr 8:22,750,336...22,774,903
JBrowse link
G Pnpla2 patatin-like phospholipase domain containing 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:3769941|PMID:16679289)
(PMID:16679289)
UniProt
RGD
PMID:16679289 GO_REF:0000024 MGI:3769941 NCBI chr 1:214,434,638...214,439,720
Ensembl chr 1:214,434,626...214,439,720
Ensembl chr 1:214,434,626...214,439,720
JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (PMID:23296834) RGD PMID:23296834 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
positive regulation of triglyceride metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd36 CD36 molecule IDA RGD PMID:23099442 RGD:11041154 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
regulation of triglyceride biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:10432298)
Ensembl
UniProt
RGD
PMID:10432298 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G Fitm2 fat storage-inducing transmembrane protein 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:3772596|PMID:18160536)
UniProt
RGD
PMID:18160536 GO_REF:0000024 MGI:3772596 NCBI chr 3:159,856,994...159,863,506
Ensembl chr 3:159,856,994...159,863,506
JBrowse link
G Thrsp thyroid hormone responsive involved_in IEA
ISO
GO_REF:0000107
(MGI:3769289|PMID:15890771)
Ensembl
RGD
PMID:15890771 GO_REF:0000107 MGI:3769289 NCBI chr 1:162,381,251...162,385,575
Ensembl chr 1:162,381,253...162,385,575
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19491
    regulation of biological process 12772
      regulation of cellular process 12273
        regulation of cellular metabolic process 5950
          regulation of triglyceride metabolic process 51
            negative regulation of triglyceride metabolic process + 13
            positive regulation of triglyceride metabolic process + 30
            regulation of triglyceride biosynthetic process + 24
            regulation of triglyceride catabolic process + 17
Path 2
Term Annotations click to browse term
  biological_process 19491
    metabolic process 11797
      primary metabolic process 10565
        lipid metabolic process 1362
          cellular lipid metabolic process 1018
            glycerolipid metabolic process 389
              acylglycerol metabolic process 144
                triglyceride metabolic process 114
                  regulation of triglyceride metabolic process 51
                    negative regulation of triglyceride metabolic process + 13
                    positive regulation of triglyceride metabolic process + 30
                    regulation of triglyceride biosynthetic process + 24
                    regulation of triglyceride catabolic process + 17
paths to the root