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ONTOLOGY REPORT - ANNOTATIONS


Term:triglyceride metabolic process
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Accession:GO:0006641 term browser browse the term
Definition:The chemical reactions and pathways involving triglyceride, any triester of glycerol. The three fatty acid residues may all be the same or differ in any permutation. Triglycerides are important components of plant oils, animal fats and animal plasma lipoproteins.
Synonyms:exact_synonym: triacylglycerol metabolic process;   triacylglycerol metabolism;   triglyceride metabolism


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triglyceride metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apoa5 apolipoprotein A5 JBrowse link 8 50,559,079 50,561,720 RGD:1624291
G Apobec1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 JBrowse link 4 155,386,367 155,414,034 RGD:1624291
G Apobr apolipoprotein B receptor JBrowse link 1 197,999,209 198,003,839 RGD:1624291
RGD:13792537
G Apoc1 apolipoprotein C1 JBrowse link 1 80,606,638 80,609,921 RGD:1624291
RGD:13792537
G Apoc3 apolipoprotein C3 JBrowse link 8 50,529,318 50,531,498 RGD:1624291
G Apoe apolipoprotein E JBrowse link 1 80,612,894 80,616,820 RGD:1600115
RGD:1624291
G Apof apolipoprotein F JBrowse link 7 2,689,501 2,690,938 RGD:1624291
G Apoh apolipoprotein H JBrowse link 10 96,640,013 96,653,939 RGD:1624291
RGD:1600115
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:1624291
G Cav1 caveolin 1 JBrowse link 4 44,597,123 44,630,206 RGD:1624291
RGD:1600115
G Cav3 caveolin 3 JBrowse link 4 144,382,945 144,398,919 RGD:1624291
G Cd36 CD36 molecule JBrowse link 4 14,150,309 14,191,498 RGD:1598387
G Cpt1a carnitine palmitoyltransferase 1A JBrowse link 1 218,568,157 218,629,679 RGD:2311348
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 JBrowse link 1 213,511,892 213,522,195 RGD:2317269
G Dbi diazepam binding inhibitor, acyl-CoA binding protein JBrowse link 13 36,147,667 36,156,076 RGD:1624291
G G6pc glucose-6-phosphatase, catalytic subunit JBrowse link 10 89,286,009 89,296,213 RGD:1624291
G Gk glycerol kinase JBrowse link X 54,227,291 54,303,897 RGD:1624291
RGD:13792537
G Gk2 glycerol kinase 2 JBrowse link 14 13,751,284 13,753,136 RGD:13792537
G Gk5 glycerol kinase 5 JBrowse link 8 103,929,093 104,001,916 RGD:13792537
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial JBrowse link 1 275,843,823 275,906,880 RGD:1624291
G Gpat4 glycerol-3-phosphate acyltransferase 4 JBrowse link 16 73,615,949 73,649,769 RGD:1624291
G Gpx1 glutathione peroxidase 1 JBrowse link 8 117,117,430 117,118,528 RGD:1624291
RGD:1600115
G Gykl1 glycerol kinase-like 1 JBrowse link 18 47,659,128 47,660,777 RGD:13792537
G Insig1 insulin induced gene 1 JBrowse link 4 342,302 350,515 RGD:1624291
G Insig2 insulin induced gene 2 JBrowse link 13 37,264,818 37,292,718 RGD:1624291
G Lipc lipase C, hepatic type JBrowse link 8 77,272,582 77,398,485 RGD:1600640
G Lmf1 lipase maturation factor 1 JBrowse link 10 14,945,185 15,031,855 RGD:1624291
G LOC100910181 apolipoprotein C-I-like RGD:13792537
G Mecp2 methyl CpG binding protein 2 JBrowse link X 156,650,389 156,713,813 RGD:1624291
G Mttp microsomal triglyceride transfer protein JBrowse link 2 243,366,181 243,407,608 RGD:1624291
G NEWGENE_2134 apolipoprotein C1 JBrowse link 1 80,606,634 80,609,954 RGD:13792537
G Nkx2-3 NK2 homeobox 3 JBrowse link 1 263,361,238 263,371,043 RGD:1624291
G Pcsk9 proprotein convertase subtilisin/kexin type 9 JBrowse link 5 126,031,368 126,053,726 RGD:1624291
G Plaat3 phospholipase A and acyltransferase 3 JBrowse link 1 222,844,238 222,877,180 RGD:1624291
RGD:1600115
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 JBrowse link 12 40,895,515 40,955,999 RGD:1624291
G Scd stearoyl-CoA desaturase JBrowse link 1 264,159,966 264,173,061 RGD:1624291
G Sel1l SEL1L adaptor subunit of ERAD E3 ubiquitin ligase JBrowse link 6 115,572,683 115,616,904 RGD:1600115
RGD:1624291
G Slc22a4 solute carrier family 22 member 4 JBrowse link 10 39,334,972 39,373,508 RGD:1624291
G Slc37a4 solute carrier family 37 member 4 JBrowse link 8 48,716,914 48,723,024 RGD:1624291
G Tnxb tenascin XB RGD:1624291
glycerol biosynthetic process from pyruvate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pck1 phosphoenolpyruvate carboxykinase 1 JBrowse link 3 171,213,936 171,219,885 RGD:8553288
RGD:13792537
RGD:1624291
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) JBrowse link 15 34,216,735 34,224,357 RGD:13792537
negative regulation of triglyceride biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 JBrowse link 7 30,003,429 30,162,095 RGD:15042869
G Sik1 salt-inducible kinase 1 JBrowse link 20 10,670,747 10,680,279 RGD:1624291
RGD:1600115
negative regulation of triglyceride catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apoc3 apolipoprotein C3 JBrowse link 8 50,529,318 50,531,498 RGD:1600115
RGD:13792537
RGD:1624291
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 JBrowse link 17 42,085,027 42,131,344 RGD:1624291
RGD:1600115
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma JBrowse link 6 51,465,696 51,501,234 RGD:6482711
G Plin5 perilipin 5 JBrowse link 9 10,956,013 10,961,782 RGD:1600115
RGD:1624291
G Sorl1 sortilin related receptor 1 JBrowse link 8 46,228,077 46,287,171 RGD:1624291
negative regulation of triglyceride metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apobec1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 JBrowse link 4 155,386,367 155,414,034 RGD:1624291
G Apoe apolipoprotein E JBrowse link 1 80,612,894 80,616,820 RGD:1624291
G Ccnc cyclin C JBrowse link 5 35,865,598 35,883,732 RGD:9590256
G Cdk8 cyclin-dependent kinase 8 JBrowse link 12 10,496,273 10,561,335 RGD:9590256
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:8552990
positive regulation of triglyceride biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acsl5 acyl-CoA synthetase long-chain family member 5 JBrowse link 1 276,240,703 276,290,012 RGD:2312807
G Apoc3 apolipoprotein C3 JBrowse link 8 50,529,318 50,531,498 RGD:10054091
G Cnep1r1 CTD nuclear envelope phosphatase 1 regulatory subunit 1 JBrowse link 19 19,899,306 19,913,605 RGD:1624291
G Ctdnep1 CTD nuclear envelope phosphatase 1 JBrowse link 10 56,590,822 56,600,235 RGD:1624291
RGD:1600115
G Dgat1 diacylglycerol O-acyltransferase 1 JBrowse link 7 117,566,363 117,576,735 RGD:10400846
G Dgat2 diacylglycerol O-acyltransferase 2 JBrowse link 1 164,113,459 164,143,818 RGD:10400884
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial JBrowse link 1 275,843,823 275,906,880 RGD:2313665
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 JBrowse link 17 42,085,027 42,131,344 RGD:1624291
RGD:1600115
G Ldlr low density lipoprotein receptor JBrowse link 8 22,750,425 22,773,305 RGD:1624291
RGD:1600115
G Mfsd2a major facilitator superfamily domain containing 2A JBrowse link 5 140,642,865 140,657,759 RGD:1624291
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 JBrowse link 1 100,554,577 100,559,896 RGD:1624291
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 JBrowse link 3 80,004,130 80,014,197 RGD:1624291
G Plin5 perilipin 5 JBrowse link 9 10,956,013 10,961,782 RGD:1600115
RGD:1624291
G Rgn regucalcin JBrowse link X 1,833,484 1,848,904 RGD:9590221
G Scarb1 scavenger receptor class B, member 1 JBrowse link 12 36,694,952 36,761,445 RGD:1624291
G Slc27a1 solute carrier family 27 member 1 JBrowse link 16 19,997,823 20,016,193 RGD:1600115
RGD:1624291
G Srebf1 sterol regulatory element binding transcription factor 1 JBrowse link 10 46,570,996 46,593,021 RGD:1600115
RGD:1624291
G Tcf7l2 transcription factor 7 like 2 JBrowse link 1 276,686,911 276,730,517 RGD:1624291
positive regulation of triglyceride catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aadac arylacetamide deacetylase JBrowse link 2 150,146,234 150,157,480 RGD:1600115
RGD:13792537
RGD:1624291
G Abhd5 abhydrolase domain containing 5, lysophosphatidic acid acyltransferase JBrowse link 8 130,973,222 131,001,448 RGD:1624291
RGD:13792537
RGD:1600115
G Apoa1 apolipoprotein A1 JBrowse link 8 50,525,091 50,526,875 RGD:13792537
G Apoa4 apolipoprotein A4 JBrowse link 8 50,536,983 50,539,371 RGD:1624291
RGD:13792537
RGD:1600115
G Apoa5 apolipoprotein A5 JBrowse link 8 50,559,079 50,561,720 RGD:1624291
RGD:13792537
RGD:1600115
G Apoc2 apolipoprotein C2 JBrowse link 1 80,589,023 80,593,991 RGD:1624291
G Apoh apolipoprotein H JBrowse link 10 96,640,013 96,653,939 RGD:8554677
G Daglb diacylglycerol lipase, beta JBrowse link 12 13,113,073 13,157,748 RGD:25671402
RGD:1624291
G Fgf21 fibroblast growth factor 21 JBrowse link 1 101,595,579 101,596,822 RGD:10401916
G Ldlr low density lipoprotein receptor JBrowse link 8 22,750,425 22,773,305 RGD:12910100
G LOC100911615 patatin-like phospholipase domain-containing protein 2-like JBrowse link 1 213,997,721 214,002,811 RGD:1600115
G Pnpla2 patatin-like phospholipase domain containing 2 JBrowse link 1 214,434,638 214,439,720 RGD:1624291
RGD:1600115
G Sirt1 sirtuin 1 JBrowse link 20 26,831,971 26,851,587 RGD:1624291
positive regulation of triglyceride metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd36 CD36 molecule JBrowse link 4 14,150,309 14,191,498 RGD:11041154
regulation of triglyceride biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C3 complement C3 JBrowse link 9 9,721,137 9,747,084 RGD:1600115
RGD:1624291
G Fitm2 fat storage-inducing transmembrane protein 2 JBrowse link 3 159,856,994 159,863,506 RGD:1624291
RGD:1600115
G Thrsp thyroid hormone responsive JBrowse link 1 162,381,251 162,385,575 RGD:1600115
RGD:1624291
regulation of triglyceride metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apoe apolipoprotein E JBrowse link 1 80,612,894 80,616,820 RGD:10059686
G Atg14 autophagy related 14 JBrowse link 15 24,343,418 24,374,776 RGD:1624291
G Gnb3 G protein subunit beta 3 JBrowse link 4 157,352,558 157,359,237 RGD:1624291
G Lmf1 lipase maturation factor 1 JBrowse link 10 14,945,185 15,031,855 RGD:1624291
G Pank2 pantothenate kinase 2 JBrowse link 3 123,807,911 123,841,797 RGD:1624291
G Serpina12 serpin family A member 12 JBrowse link 6 127,696,501 127,711,238 RGD:1624291
RGD:1600115
G Tbl1xr1 TBL1X receptor 1 JBrowse link 2 107,221,913 107,359,229 RGD:1624291
G Thrb thyroid hormone receptor beta JBrowse link 15 8,890,578 9,239,815 RGD:2315101
triglyceride acyl-chain remodeling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pnpla3 patatin-like phospholipase domain containing 3 JBrowse link 7 125,034,760 125,056,165 RGD:1624291
triglyceride biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acsl1 acyl-CoA synthetase long-chain family member 1 JBrowse link 16 48,937,456 49,003,898 RGD:2312800
G Acsl4 acyl-CoA synthetase long-chain family member 4 JBrowse link X 113,596,247 113,660,024 RGD:2312800
G Acsl6 acyl-CoA synthetase long-chain family member 6 JBrowse link 10 39,654,771 39,717,592 RGD:2312800
G Dgat1 diacylglycerol O-acyltransferase 1 JBrowse link 7 117,566,363 117,576,735 RGD:1625586
RGD:13792537
RGD:1624291
RGD:1600115
G Dgat2 diacylglycerol O-acyltransferase 2 JBrowse link 1 164,113,459 164,143,818 RGD:1600115
RGD:13792537
RGD:1624291
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial JBrowse link 1 275,843,823 275,906,880 RGD:1600115
RGD:13792537
RGD:1624291
G Gpat2 glycerol-3-phosphate acyltransferase 2, mitochondrial JBrowse link 3 119,949,921 120,003,090 RGD:1624291
RGD:13792537
G Gpat3 glycerol-3-phosphate acyltransferase 3 JBrowse link 14 10,343,287 10,396,565 RGD:1600115
RGD:1624291
G Gpat4 glycerol-3-phosphate acyltransferase 4 JBrowse link 16 73,615,949 73,649,769 RGD:1624291
G Lpin1 lipin 1 JBrowse link 6 41,796,214 41,905,149 RGD:13792537
G Lpin2 lipin 2 JBrowse link 9 119,517,101 119,591,533 RGD:13792537
G Lpin3 lipin 3 JBrowse link 3 156,874,805 156,899,601 RGD:13792537
G Lpl lipoprotein lipase JBrowse link 16 22,537,687 22,561,487 RGD:70246
G Mogat1 monoacylglycerol O-acyltransferase 1 JBrowse link 9 84,405,481 84,418,657 RGD:13792537
G Mogat2 monoacylglycerol O-acyltransferase 2 JBrowse link 1 164,181,762 164,205,222 RGD:1624291
G Mogat3 monoacylglycerol O-acyltransferase 3 JBrowse link 12 22,708,622 22,710,787 RGD:1624291
RGD:13792537
G Pnpla3 patatin-like phospholipase domain containing 3 JBrowse link 7 125,034,760 125,056,165 RGD:1624291
triglyceride catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07034648.1 RGD:13792537
G Apoa5 apolipoprotein A5 JBrowse link 8 50,559,079 50,561,720 RGD:1624291
RGD:1600115
G Apob apolipoprotein B JBrowse link 6 33,176,826 33,216,381 RGD:1626404
RGD:1624291
G Apoc3 apolipoprotein C3 JBrowse link 8 50,529,318 50,531,498 RGD:1624291
RGD:1600115
G Cps1 carbamoyl-phosphate synthase 1 JBrowse link 9 74,113,437 74,236,274 RGD:1624291
G Ddhd2 DDHD domain containing 2 JBrowse link 16 71,090,096 71,120,713 RGD:1624291
G Lipc lipase C, hepatic type JBrowse link 8 77,272,582 77,398,485 RGD:1600115
RGD:13792537
RGD:1624291
G Lipe lipase E, hormone sensitive type JBrowse link 1 82,248,031 82,266,727 RGD:1581873
RGD:1624291
RGD:1600115
G Lipg lipase G, endothelial type JBrowse link 18 70,903,528 70,924,434 RGD:13792537
G Liph lipase H JBrowse link 11 82,680,167 82,732,145 RGD:13792537
G Lipi lipase I JBrowse link 11 13,960,246 13,999,869 RGD:13792537
G LOC100911615 patatin-like phospholipase domain-containing protein 2-like JBrowse link 1 213,997,721 214,002,811 RGD:1600115
RGD:13792537
G Lpl lipoprotein lipase JBrowse link 16 22,537,687 22,561,487 RGD:1624291
RGD:13792537
RGD:1600115
G Mgll monoglyceride lipase JBrowse link 4 120,671,436 120,773,458 RGD:1600115
G Plb1 phospholipase B1 JBrowse link 6 25,375,699 25,507,108 RGD:633237
RGD:30309923
G Pnliprp2 pancreatic lipase related protein 2 JBrowse link 1 279,896,973 279,927,600 RGD:1624291
RGD:1600115
G Pnpla1 patatin-like phospholipase domain containing 1 JBrowse link 20 6,101,061 6,143,762 RGD:13792537
G Pnpla2 patatin-like phospholipase domain containing 2 JBrowse link 1 214,434,638 214,439,720 RGD:1600115
RGD:1624291
RGD:13792537
G Pnpla3 patatin-like phospholipase domain containing 3 JBrowse link 7 125,034,760 125,056,165 RGD:1624291
RGD:13792537
G Pnpla4 patatin like phospholipase domain containing 4 JBrowse link X 45,519,406 45,522,988 RGD:13792537
G Pnpla5 patatin-like phospholipase domain containing 5 JBrowse link 7 124,988,524 124,999,137 RGD:13792537
triglyceride mobilization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apob apolipoprotein B JBrowse link 6 33,176,826 33,216,381 RGD:1624291
RGD:13792537
G Apoc3 apolipoprotein C3 JBrowse link 8 50,529,318 50,531,498 RGD:1624291
G Il6st interleukin 6 signal transducer JBrowse link 2 44,279,199 44,319,427 RGD:1626687
G Lpin1 lipin 1 JBrowse link 6 41,796,214 41,905,149 RGD:1624291
G Sirt1 sirtuin 1 JBrowse link 20 26,831,971 26,851,587 RGD:1624291
G Slc27a5 solute carrier family 27 member 5 JBrowse link 1 65,576,599 65,587,192 RGD:1624291
RGD:13792537

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    cellular process 18618
      cellular metabolic process 10918
        cellular lipid metabolic process 1043
          neutral lipid metabolic process 145
            acylglycerol metabolic process 143
              triglyceride metabolic process 113
                negative regulation of triglyceride metabolic process + 12
                positive regulation of triglyceride metabolic process + 31
                regulation of triglyceride metabolic process + 50
                triglyceride acyl-chain remodeling 1
                triglyceride biosynthetic process + 39
                triglyceride catabolic process + 35
                triglyceride mobilization 6
Path 2
Term Annotations click to browse term
  biological_process 19858
    metabolic process 12097
      primary metabolic process 10750
        lipid metabolic process 1363
          cellular lipid metabolic process 1043
            neutral lipid metabolic process 145
              acylglycerol metabolic process 143
                triglyceride metabolic process 113
                  negative regulation of triglyceride metabolic process + 12
                  positive regulation of triglyceride metabolic process + 31
                  regulation of triglyceride metabolic process + 50
                  triglyceride acyl-chain remodeling 1
                  triglyceride biosynthetic process + 39
                  triglyceride catabolic process + 35
                  triglyceride mobilization 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.