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ONTOLOGY REPORT - ANNOTATIONS

Term:stress-activated protein kinase signaling cascade
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Accession:GO:0031098 term browser browse the term
Definition:The series of molecular signals in which a stress-activated protein kinase (SAPK) cascade relays a signal.
Synonyms:exact_synonym: SAPK signaling pathway;   SAPK signalling pathway;   stress-activated protein kinase signaling pathway;   stress-activated protein kinase signalling pathway
 narrow_synonym: JNK signaling pathway;   JNK signalling pathway


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stress-activated protein kinase signaling cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKR1B1 aldo-keto reductase family 1 member B ISO RGD PMID:16669970 RGD:1626090 NCBI chr 7:134,442,350...134,459,239
Ensembl chr 7:134,442,356...134,459,284 		JBrowse link
G GFRAL GDNF family receptor alpha like involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16086688) Ensembl
MGI		 PMID:16086688 GO_REF:0000107 NCBI chr 6:55,327,469...55,402,493
Ensembl chr 6:55,327,469...55,402,493 		JBrowse link
G KAT7 lysine acetyltransferase 7 involved_in IDA (PMID:21856198) CAFA PMID:21856198 NCBI chr17:49,788,681...49,835,026
Ensembl chr17:49,788,624...49,835,026 		JBrowse link
G MAP2K3 mitogen-activated protein kinase kinase 3 involved_in IDA (PMID:8622669) UniProt PMID:8622669 NCBI chr17:21,284,711...21,315,240
Ensembl chr17:21,284,672...21,315,232 		JBrowse link
G MAP2K6 mitogen-activated protein kinase kinase 6 involved_in IDA (PMID:35857590) UniProt PMID:35857590 NCBI chr17:69,414,697...69,553,865
Ensembl chr17:69,414,697...69,553,865 		JBrowse link
G MAP3K20 mitogen-activated protein kinase kinase kinase 20 involved_in IDA (PMID:35857590) UniProt PMID:35857590 NCBI chr 2:173,075,517...173,268,015
Ensembl chr 2:173,075,435...173,268,015 		JBrowse link
G MAPK11 mitogen-activated protein kinase 11 involved_in IDA (PMID:35857590) UniProt PMID:35857590 NCBI chr22:50,263,713...50,270,380
Ensembl chr22:50,263,713...50,270,767 		JBrowse link
G MAPK14 mitogen-activated protein kinase 14 involved_in IDA (PMID:35857590) UniProt PMID:35857590 NCBI chr 6:36,027,808...36,124,214
Ensembl chr 6:36,027,782...36,111,236 		JBrowse link
G RHOA ras homolog family member A ISO RGD PMID:17369826 RGD:1642964 NCBI chr 3:49,359,145...49,411,976
Ensembl chr 3:49,359,139...49,412,998 		JBrowse link
G USP25 ubiquitin specific peptidase 25 involved_in ISO (PMID:23042150) MGI PMID:23042150 NCBI chr21:15,729,982...15,880,064
Ensembl chr21:15,729,982...15,880,064 		JBrowse link
negative regulation of stress-activated MAPK cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DUSP10 dual specificity phosphatase 10 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19696743) Ensembl
MGI		 PMID:19696743 GO_REF:0000107 NCBI chr 1:221,701,424...221,742,089
Ensembl chr 1:221,701,424...221,742,089 		JBrowse link
G FOXM1 forkhead box M1 involved_in IMP (PMID:19696738) BHF-UCL PMID:19696738 NCBI chr12:2,857,680...2,877,174
Ensembl chr12:2,857,680...2,877,174 		JBrowse link
G FOXO1 forkhead box O1 involved_in IDA (PMID:19696738) BHF-UCL PMID:19696738 NCBI chr13:40,555,667...40,666,641
Ensembl chr13:40,555,667...40,666,641 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656 		JBrowse link
G IGBP1 immunoglobulin binding protein 1 involved_in IMP (PMID:17438131) UniProt PMID:17438131 NCBI chr  X:70,133,447...70,166,324
Ensembl chr  X:70,133,447...70,166,324 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor involved_in ISS UniProt GO_REF:0000024 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951 		JBrowse link
G PBK PDZ binding kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21715333) Ensembl
MGI		 PMID:21715333 GO_REF:0000107 NCBI chr 8:27,809,624...27,837,817
Ensembl chr 8:27,809,624...27,838,082 		JBrowse link
G PPIA peptidylprolyl isomerase A involved_in IMP (PMID:26095851) UniProt PMID:26095851 NCBI chr 7:44,796,681...44,803,117
Ensembl chr 7:44,796,680...44,824,564 		JBrowse link
G QARS1 glutaminyl-tRNA synthetase 1 involved_in IDA (PMID:11096076) CAFA PMID:11096076 NCBI chr 3:49,095,932...49,104,757
Ensembl chr 3:49,095,932...49,105,130 		JBrowse link
negative regulation of stress-activated protein kinase signaling cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MAP3K20 mitogen-activated protein kinase kinase kinase 20 involved_in IDA (PMID:35857590) UniProt PMID:35857590 NCBI chr 2:173,075,517...173,268,015
Ensembl chr 2:173,075,435...173,268,015 		JBrowse link
positive regulation of stress-activated MAPK cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARL6IP5 ADP ribosylation factor like GTPase 6 interacting protein 5 involved_in IMP (PMID:18387645) UniProt PMID:18387645 NCBI chr 3:69,084,937...69,106,092
Ensembl chr 3:69,084,937...69,106,092 		JBrowse link
G CARD9 caspase recruitment domain family member 9 involved_in
acts_upstream_of_or_within		 ISS
IDA
IEA		 (PMID:17187069) UniProt
MGI
Ensembl		 PMID:17187069 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:136,363,956...136,373,669
Ensembl chr 9:136,363,956...136,373,681 		JBrowse link
G CLEC7A C-type lectin domain containing 7A involved_in ISO (MGI:5803730|PMID:27288407) UniProt PMID:27288407 MGI:5803730 NCBI chr12:10,116,777...10,130,304
Ensembl chr12:10,116,777...10,130,258 		JBrowse link
G CRHR2 corticotropin releasing hormone receptor 2 ISO RGD PMID:19211730 RGD:5130956 NCBI chr 7:30,651,942...30,700,103
Ensembl chr 7:30,651,942...30,700,129 		JBrowse link
G EIF2AK2 eukaryotic translation initiation factor 2 alpha kinase 2 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:37,099,210...37,156,980
Ensembl chr 2:37,099,210...37,157,522 		JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase ISO RGD PMID:17161379 RGD:5508698 NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001 		JBrowse link
G IGFBP6 insulin like growth factor binding protein 6 involved_in IDA (PMID:24003225) UniProt PMID:24003225 NCBI chr12:53,097,667...53,102,340
Ensembl chr12:53,097,436...53,102,345 		JBrowse link
G IL1A interleukin 1 alpha involved_in ISO
IEA		 RGD
Ensembl		 PMID:15671867 GO_REF:0000107 RGD:1358666 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493 		JBrowse link
G IL1B interleukin 1 beta ISO RGD PMID:12629164 PMID:15671867 RGD:1358666 RGD:1626685 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL26 interleukin 26 involved_in IDA (PMID:18483078) UniProt PMID:18483078 NCBI chr12:68,201,349...68,225,810
Ensembl chr12:68,201,349...68,225,810 		JBrowse link
G INAVA innate immunity activator involved_in IMP (PMID:28436939) UniProt PMID:28436939 NCBI chr 1:200,891,531...200,915,742
Ensembl chr 1:200,891,048...200,915,742 		JBrowse link
G KISS1 KiSS-1 metastasis suppressor NOT ISO RGD PMID:16222076 RGD:1599289 NCBI chr 1:204,190,341...204,196,491
Ensembl chr 1:204,190,341...204,196,491 		JBrowse link
G KLHDC10 kelch domain containing 10 involved_in IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 7:130,070,534...130,135,705
Ensembl chr 7:130,070,534...130,135,705 		JBrowse link
G MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2 involved_in ISO
IEA		 RGD
Ensembl		 PMID:12024021 GO_REF:0000107 RGD:2302280 NCBI chr22:50,600,793...50,613,978
Ensembl chr22:50,600,793...50,613,981 		JBrowse link
G MID1 midline 1 involved_in IMP (PMID:17438131) UniProt PMID:17438131 NCBI chr  X:10,445,310...10,833,683
Ensembl chr  X:10,445,310...10,833,654 		JBrowse link
G NOD1 nucleotide binding oligomerization domain containing 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18261938) Ensembl
MGI		 PMID:18261938 GO_REF:0000107 NCBI chr 7:30,424,527...30,478,784
Ensembl chr 7:30,424,527...30,478,784 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within
involved_in		 IDA
IEA		 (PMID:17187069) MGI
Ensembl		 PMID:17187069 GO_REF:0000107 NCBI chr16:50,693,606...50,733,075
Ensembl chr16:50,693,588...50,733,077 		JBrowse link
G PDCD10 programmed cell death 10 involved_in IDA (PMID:22652780) UniProt PMID:22652780 NCBI chr 3:167,683,298...167,734,892
Ensembl chr 3:167,683,298...167,734,939 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11894097)
(PMID:11894098), (PMID:18261938)		 Ensembl
MGI		 PMID:11894097 PMID:11894098 PMID:18261938 GO_REF:0000107 NCBI chr 8:89,757,816...89,791,064
Ensembl chr 8:89,757,806...89,791,064 		JBrowse link
G SCIMP SLP adaptor and CSK interacting membrane protein involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:5,208,920...5,234,860
Ensembl chr17:5,208,920...5,234,860 		JBrowse link
G SEMA4C semaphorin 4C involved_in IDA (PMID:17498836) UniProt PMID:17498836 NCBI chr 2:96,859,718...96,870,830
Ensembl chr 2:96,859,718...96,870,757 		JBrowse link
G STK25 serine/threonine kinase 25 involved_in IDA (PMID:22652780) UniProt PMID:22652780 NCBI chr 2:241,492,670...241,509,572
Ensembl chr 2:241,492,670...241,509,730 		JBrowse link
G TAOK1 TAO kinase 1 involved_in IMP (PMID:17396146) UniProt PMID:17396146 NCBI chr17:29,390,363...29,551,903
Ensembl chr17:29,390,363...29,551,903 		JBrowse link
G TAOK2 TAO kinase 2 involved_in IMP (PMID:17396146) UniProt PMID:17396146 NCBI chr16:29,973,868...29,992,261
Ensembl chr16:29,973,868...29,992,261 		JBrowse link
G TAOK3 TAO kinase 3 involved_in IMP (PMID:17396146) UniProt PMID:17396146 NCBI chr12:118,149,801...118,372,907
Ensembl chr12:118,149,801...118,372,907 		JBrowse link
G TGFB2 transforming growth factor beta 2 involved_in IDA (PMID:17192487) BHF-UCL PMID:17192487 NCBI chr 1:218,345,336...218,444,619
Ensembl chr 1:218,345,336...218,444,619 		JBrowse link
G TLR4 toll like receptor 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18261938) Ensembl
MGI		 PMID:18261938 GO_REF:0000107 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
regulation of stress-activated MAPK cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FAS Fas cell surface death receptor involved_in IMP
IEA
IBA		 (PMID:11096076) CAFA
TreeGrafter
GO_Central		 PMID:11096076 GO_REF:0000033 GO_REF:0000118 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605 		JBrowse link
G GREM1 gremlin 1, DAN family BMP antagonist NOT|involved_in ISS (PMID:9660951) BHF-UCL PMID:9660951 NCBI chr15:32,718,004...32,745,106
Ensembl chr15:32,718,004...32,745,106 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656 		JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 involved_in TAS
IEA		 (PMID:19565474) UniProt PMID:19565474 GO_REF:0000117 NCBI chr15:66,386,912...66,491,544
Ensembl chr15:66,386,837...66,491,656 		JBrowse link
G MAP2K2 mitogen-activated protein kinase kinase 2 involved_in TAS
IEA		 (PMID:19565474) UniProt PMID:19565474 GO_REF:0000117 NCBI chr19:4,090,321...4,124,122
Ensembl chr19:4,090,321...4,124,122 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 involved_in TAS
IEA		 (PMID:19565474) UniProt PMID:19565474 GO_REF:0000117 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 involved_in TAS
IEA		 (PMID:19565474) UniProt PMID:19565474 GO_REF:0000117 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G NBR1 NBR1 autophagy cargo receptor involved_in IEA
ISS		 Ensembl
BHF-UCL		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:43,170,409...43,211,688
Ensembl chr17:43,170,481...43,211,689 		JBrowse link
G PAGE4 PAGE family member 4 involved_in TAS (PMID:30658679) UniProt PMID:30658679 NCBI chr  X:49,829,260...49,834,264
Ensembl chr  X:49,829,260...49,834,264 		JBrowse link
G PRDX1 peroxiredoxin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16880205) Ensembl
MGI		 PMID:16880205 GO_REF:0000107 NCBI chr 1:45,511,051...45,522,890
Ensembl chr 1:45,510,914...45,542,732 		JBrowse link
regulation of stress-activated protein kinase signaling cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ZMPSTE24 zinc metallopeptidase STE24 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16079796) Ensembl
MGI		 PMID:16079796 GO_REF:0000107 NCBI chr 1:40,258,236...40,294,180
Ensembl chr 1:40,258,041...40,294,180 		JBrowse link
stress-activated MAPK cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen ISO RGD PMID:21367774 RGD:5129174 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576 		JBrowse link
G CARD9 caspase recruitment domain family member 9 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:17187069) Ensembl
MGI		 PMID:17187069 GO_REF:0000107 NCBI chr 9:136,363,956...136,373,669
Ensembl chr 9:136,363,956...136,373,681 		JBrowse link
G CCM2 CCM2 scaffold protein involved_in TAS (PMID:16037064) UniProt PMID:16037064 NCBI chr 7:44,999,746...45,076,470
Ensembl chr 7:44,999,475...45,076,469 		JBrowse link
G CD2AP CD2 associated protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15213232) Ensembl
MGI		 PMID:15213232 GO_REF:0000107 NCBI chr 6:47,477,789...47,627,263
Ensembl chr 6:47,477,789...47,627,263 		JBrowse link
G CRYAB crystallin alpha B involved_in ISO
IEA		 RGD
Ensembl		 PMID:18420382 GO_REF:0000107 RGD:2303631 NCBI chr11:111,908,564...111,923,740
Ensembl chr11:111,908,564...111,923,722 		JBrowse link
G DUSP10 dual specificity phosphatase 10 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:19696743) Ensembl
MGI		 PMID:19696743 GO_REF:0000107 NCBI chr 1:221,701,424...221,742,089
Ensembl chr 1:221,701,424...221,742,089 		JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta involved_in TAS Reactome Reactome:R-HSA-450294 NCBI chr 8:42,271,302...42,332,460
Ensembl chr 8:42,271,302...42,332,460 		JBrowse link
G MAP2K6 mitogen-activated protein kinase kinase 6 involved_in IDA (PMID:8663524), (PMID:9218798) UniProt PMID:8663524 PMID:9218798 NCBI chr17:69,414,697...69,553,865
Ensembl chr17:69,414,697...69,553,865 		JBrowse link
G MAP2K7 mitogen-activated protein kinase kinase 7 involved_in IDA
IBA		 (PMID:9535930) UniProt
GO_Central		 PMID:9535930 GO_REF:0000033 NCBI chr19:7,903,877...7,914,478
Ensembl chr19:7,903,843...7,914,478 		JBrowse link
G MAP3K13 mitogen-activated protein kinase kinase kinase 13 involved_in IDA (PMID:11726277) UniProt PMID:11726277 NCBI chr 3:185,282,961...185,489,094
Ensembl chr 3:185,282,941...185,489,094 		JBrowse link
G MAP3K20 mitogen-activated protein kinase kinase kinase 20 involved_in IEA
IDA		 (PMID:11836244), (PMID:20559024), (PMID:32289254), (PMID:32610081) Ensembl
UniProt		 PMID:11836244 PMID:20559024 PMID:32289254 PMID:32610081 GO_REF:0000107 NCBI chr 2:173,075,517...173,268,015
Ensembl chr 2:173,075,435...173,268,015 		JBrowse link
G MAP3K5 mitogen-activated protein kinase kinase kinase 5 involved_in IDA (PMID:11096076) CAFA PMID:11096076 NCBI chr 6:136,557,046...136,793,091
Ensembl chr 6:136,557,046...136,793,097 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 involved_in IDA (PMID:9079627) UniProt PMID:9079627 NCBI chr 6:90,513,579...90,587,072
Ensembl chr 6:90,513,573...90,587,086 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 involved_in IDA (PMID:11096076) CAFA PMID:11096076 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK11 mitogen-activated protein kinase 11 involved_in IDA (PMID:35857590), (PMID:8663524) UniProt PMID:8663524 PMID:35857590 NCBI chr22:50,263,713...50,270,380
Ensembl chr22:50,263,713...50,270,767 		JBrowse link
G MAPK13 mitogen-activated protein kinase 13 involved_in IDA (PMID:9218798) UniProt PMID:9218798 NCBI chr 6:36,130,513...36,144,521
Ensembl chr 6:36,127,809...36,144,524 		JBrowse link
G MAPK14 mitogen-activated protein kinase 14 involved_in ISO
IDA		 (PMID:35857590) RGD
UniProt		 PMID:16407200 PMID:35857590 RGD:1580544 NCBI chr 6:36,027,808...36,124,214
Ensembl chr 6:36,027,782...36,111,236 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 involved_in IDA (PMID:11096076) CAFA PMID:11096076 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 involved_in IDA (PMID:11096076) CAFA PMID:11096076 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360 		JBrowse link
G NOD1 nucleotide binding oligomerization domain containing 1 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:18261938) Ensembl
MGI		 PMID:18261938 GO_REF:0000107 NCBI chr 7:30,424,527...30,478,784
Ensembl chr 7:30,424,527...30,478,784 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:18261938) Ensembl
MGI		 PMID:18261938 GO_REF:0000107 NCBI chr16:50,693,606...50,733,075
Ensembl chr16:50,693,588...50,733,077 		JBrowse link
G PBK PDZ binding kinase involved_in
acts_upstream_of		 IEA
ISO		 (PMID:21715333) Ensembl
MGI		 PMID:21715333 GO_REF:0000107 NCBI chr 8:27,809,624...27,837,817
Ensembl chr 8:27,809,624...27,838,082 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:11894098), (PMID:18261938)
(PMID:11894097)		 Ensembl
MGI		 PMID:11894097 PMID:11894098 PMID:18261938 GO_REF:0000107 NCBI chr 8:89,757,816...89,791,064
Ensembl chr 8:89,757,806...89,791,064 		JBrowse link
G TAOK2 TAO kinase 2 involved_in IDA (PMID:11279118) UniProt PMID:11279118 NCBI chr16:29,973,868...29,992,261
Ensembl chr16:29,973,868...29,992,261 		JBrowse link
G TLR4 toll like receptor 4 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:18261938) Ensembl
MGI		 PMID:18261938 GO_REF:0000107 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19669
    cellular process 18301
      cellular response to stimulus 8383
        cellular response to stress 2150
          stress-activated protein kinase signaling cascade 67
            negative regulation of stress-activated protein kinase signaling cascade + 10
            positive regulation of stress-activated protein kinase signaling cascade + 27
            regulation of stress-activated protein kinase signaling cascade + 47
            stress-activated MAPK cascade + 60
Path 2
Term Annotations click to browse term
  biological_process 19669
    biological regulation 13404
      regulation of biological process 13020
        regulation of cellular process 12453
          signal transduction 6575
            intracellular signal transduction 2993
              stress-activated protein kinase signaling cascade 67
                negative regulation of stress-activated protein kinase signaling cascade + 10
                positive regulation of stress-activated protein kinase signaling cascade + 27
                regulation of stress-activated protein kinase signaling cascade + 47
                stress-activated MAPK cascade + 60
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