Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of stress-activated protein kinase signaling cascade
go back to main search page
Accession:GO:0070302 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of signaling via a stress-activated protein kinase signaling cascade.
Synonyms:exact_synonym: regulation of SAPK signaling pathway;   regulation of stress-activated protein kinase signaling pathway;   regulation of stress-activated protein kinase signalling pathway


show annotations for term's descendants           Sort by:
regulation of stress-activated protein kinase signaling cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ZMPSTE24 zinc metallopeptidase STE24 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16079796) Ensembl
MGI		 PMID:16079796 GO_REF:0000107 NCBI chr 1:40,258,236...40,294,180
Ensembl chr 1:40,258,041...40,294,180 		JBrowse link
negative regulation of stress-activated MAPK cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DUSP10 dual specificity phosphatase 10 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19696743) Ensembl
MGI		 PMID:19696743 GO_REF:0000107 NCBI chr 1:221,701,424...221,742,089
Ensembl chr 1:221,701,424...221,742,089 		JBrowse link
G FOXM1 forkhead box M1 involved_in IMP (PMID:19696738) BHF-UCL PMID:19696738 NCBI chr12:2,857,680...2,877,174
Ensembl chr12:2,857,680...2,877,174 		JBrowse link
G FOXO1 forkhead box O1 involved_in IDA (PMID:19696738) BHF-UCL PMID:19696738 NCBI chr13:40,555,667...40,666,641
Ensembl chr13:40,555,667...40,666,641 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656 		JBrowse link
G IGBP1 immunoglobulin binding protein 1 involved_in IMP (PMID:17438131) UniProt PMID:17438131 NCBI chr  X:70,133,447...70,166,324
Ensembl chr  X:70,133,447...70,166,324 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor involved_in ISS UniProt GO_REF:0000024 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951 		JBrowse link
G PBK PDZ binding kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21715333) Ensembl
MGI		 PMID:21715333 GO_REF:0000107 NCBI chr 8:27,809,624...27,837,817
Ensembl chr 8:27,809,624...27,838,082 		JBrowse link
G PPIA peptidylprolyl isomerase A involved_in IMP (PMID:26095851) UniProt PMID:26095851 NCBI chr 7:44,796,681...44,803,117
Ensembl chr 7:44,796,680...44,824,564 		JBrowse link
G QARS1 glutaminyl-tRNA synthetase 1 involved_in IDA (PMID:11096076) CAFA PMID:11096076 NCBI chr 3:49,095,932...49,104,757
Ensembl chr 3:49,095,932...49,105,130 		JBrowse link
negative regulation of stress-activated protein kinase signaling cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MAP3K20 mitogen-activated protein kinase kinase kinase 20 involved_in IDA (PMID:35857590) UniProt PMID:35857590 NCBI chr 2:173,075,517...173,268,015
Ensembl chr 2:173,075,435...173,268,015 		JBrowse link
positive regulation of stress-activated MAPK cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARL6IP5 ADP ribosylation factor like GTPase 6 interacting protein 5 involved_in IMP (PMID:18387645) UniProt PMID:18387645 NCBI chr 3:69,084,937...69,106,092
Ensembl chr 3:69,084,937...69,106,092 		JBrowse link
G CARD9 caspase recruitment domain family member 9 acts_upstream_of_or_within
involved_in		 IDA
IEA
ISS		 (PMID:17187069) MGI
Ensembl
UniProt		 PMID:17187069 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:136,363,956...136,373,669
Ensembl chr 9:136,363,956...136,373,681 		JBrowse link
G CLEC7A C-type lectin domain containing 7A involved_in ISO (MGI:5803730|PMID:27288407) UniProt PMID:27288407 MGI:5803730 NCBI chr12:10,116,777...10,130,304
Ensembl chr12:10,116,777...10,130,258 		JBrowse link
G CRHR2 corticotropin releasing hormone receptor 2 ISO RGD PMID:19211730 RGD:5130956 NCBI chr 7:30,651,942...30,700,103
Ensembl chr 7:30,651,942...30,700,129 		JBrowse link
G EIF2AK2 eukaryotic translation initiation factor 2 alpha kinase 2 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:37,099,210...37,156,980
Ensembl chr 2:37,099,210...37,157,522 		JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase ISO RGD PMID:17161379 RGD:5508698 NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001 		JBrowse link
G IGFBP6 insulin like growth factor binding protein 6 involved_in IDA (PMID:24003225) UniProt PMID:24003225 NCBI chr12:53,097,667...53,102,340
Ensembl chr12:53,097,436...53,102,345 		JBrowse link
G IL1A interleukin 1 alpha involved_in ISO
IEA		 RGD
Ensembl		 PMID:15671867 GO_REF:0000107 RGD:1358666 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493 		JBrowse link
G IL1B interleukin 1 beta ISO RGD PMID:12629164 PMID:15671867 RGD:1358666 RGD:1626685 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL26 interleukin 26 involved_in IDA (PMID:18483078) UniProt PMID:18483078 NCBI chr12:68,201,349...68,225,810
Ensembl chr12:68,201,349...68,225,810 		JBrowse link
G INAVA innate immunity activator involved_in IMP (PMID:28436939) UniProt PMID:28436939 NCBI chr 1:200,891,531...200,915,742
Ensembl chr 1:200,891,048...200,915,742 		JBrowse link
G KISS1 KiSS-1 metastasis suppressor NOT ISO RGD PMID:16222076 RGD:1599289 NCBI chr 1:204,190,341...204,196,491
Ensembl chr 1:204,190,341...204,196,491 		JBrowse link
G KLHDC10 kelch domain containing 10 involved_in IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 7:130,070,534...130,135,705
Ensembl chr 7:130,070,534...130,135,705 		JBrowse link
G MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2 involved_in ISO
IEA		 RGD
Ensembl		 PMID:12024021 GO_REF:0000107 RGD:2302280 NCBI chr22:50,600,793...50,613,978
Ensembl chr22:50,600,793...50,613,981 		JBrowse link
G MID1 midline 1 involved_in IMP (PMID:17438131) UniProt PMID:17438131 NCBI chr  X:10,445,310...10,833,683
Ensembl chr  X:10,445,310...10,833,654 		JBrowse link
G NOD1 nucleotide binding oligomerization domain containing 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18261938) Ensembl
MGI		 PMID:18261938 GO_REF:0000107 NCBI chr 7:30,424,527...30,478,784
Ensembl chr 7:30,424,527...30,478,784 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within
involved_in		 IDA
IEA		 (PMID:17187069) MGI
Ensembl		 PMID:17187069 GO_REF:0000107 NCBI chr16:50,693,606...50,733,075
Ensembl chr16:50,693,588...50,733,077 		JBrowse link
G PDCD10 programmed cell death 10 involved_in IDA (PMID:22652780) UniProt PMID:22652780 NCBI chr 3:167,683,298...167,734,892
Ensembl chr 3:167,683,298...167,734,939 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11894097)
(PMID:11894098), (PMID:18261938)		 Ensembl
MGI		 PMID:11894097 PMID:11894098 PMID:18261938 GO_REF:0000107 NCBI chr 8:89,757,816...89,791,064
Ensembl chr 8:89,757,806...89,791,064 		JBrowse link
G SCIMP SLP adaptor and CSK interacting membrane protein involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:5,208,920...5,234,860
Ensembl chr17:5,208,920...5,234,860 		JBrowse link
G SEMA4C semaphorin 4C involved_in IDA (PMID:17498836) UniProt PMID:17498836 NCBI chr 2:96,859,718...96,870,830
Ensembl chr 2:96,859,718...96,870,757 		JBrowse link
G STK25 serine/threonine kinase 25 involved_in IDA (PMID:22652780) UniProt PMID:22652780 NCBI chr 2:241,492,670...241,509,572
Ensembl chr 2:241,492,670...241,509,730 		JBrowse link
G TAOK1 TAO kinase 1 involved_in IMP (PMID:17396146) UniProt PMID:17396146 NCBI chr17:29,390,363...29,551,903
Ensembl chr17:29,390,363...29,551,903 		JBrowse link
G TAOK2 TAO kinase 2 involved_in IMP (PMID:17396146) UniProt PMID:17396146 NCBI chr16:29,973,868...29,992,261
Ensembl chr16:29,973,868...29,992,261 		JBrowse link
G TAOK3 TAO kinase 3 involved_in IMP (PMID:17396146) UniProt PMID:17396146 NCBI chr12:118,149,801...118,372,907
Ensembl chr12:118,149,801...118,372,907 		JBrowse link
G TGFB2 transforming growth factor beta 2 involved_in IDA (PMID:17192487) BHF-UCL PMID:17192487 NCBI chr 1:218,345,336...218,444,619
Ensembl chr 1:218,345,336...218,444,619 		JBrowse link
G TLR4 toll like receptor 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18261938) Ensembl
MGI		 PMID:18261938 GO_REF:0000107 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
regulation of stress-activated MAPK cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FAS Fas cell surface death receptor involved_in IMP
IEA
IBA		 (PMID:11096076) CAFA
TreeGrafter
GO_Central		 PMID:11096076 GO_REF:0000033 GO_REF:0000118 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605 		JBrowse link
G GREM1 gremlin 1, DAN family BMP antagonist NOT|involved_in ISS (PMID:9660951) BHF-UCL PMID:9660951 NCBI chr15:32,718,004...32,745,106
Ensembl chr15:32,718,004...32,745,106 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656 		JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 involved_in TAS
IEA		 (PMID:19565474) UniProt PMID:19565474 GO_REF:0000117 NCBI chr15:66,386,912...66,491,544
Ensembl chr15:66,386,837...66,491,656 		JBrowse link
G MAP2K2 mitogen-activated protein kinase kinase 2 involved_in TAS
IEA		 (PMID:19565474) UniProt PMID:19565474 GO_REF:0000117 NCBI chr19:4,090,321...4,124,122
Ensembl chr19:4,090,321...4,124,122 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 involved_in TAS
IEA		 (PMID:19565474) UniProt PMID:19565474 GO_REF:0000117 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 involved_in TAS
IEA		 (PMID:19565474) UniProt PMID:19565474 GO_REF:0000117 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G NBR1 NBR1 autophagy cargo receptor involved_in IEA
ISS		 Ensembl
BHF-UCL		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:43,170,409...43,211,688
Ensembl chr17:43,170,481...43,211,689 		JBrowse link
G PAGE4 PAGE family member 4 involved_in TAS (PMID:30658679) UniProt PMID:30658679 NCBI chr  X:49,829,260...49,834,264
Ensembl chr  X:49,793,653...49,834,264 		JBrowse link
G PRDX1 peroxiredoxin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16880205) Ensembl
MGI		 PMID:16880205 GO_REF:0000107 NCBI chr 1:45,511,051...45,522,890
Ensembl chr 1:45,510,914...45,542,732 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19612
    regulation of biological process 12981
      regulation of cellular process 12412
        regulation of cellular response to stress 596
          regulation of stress-activated protein kinase signaling cascade 47
            negative regulation of stress-activated protein kinase signaling cascade + 10
            positive regulation of stress-activated protein kinase signaling cascade + 27
            regulation of stress-activated MAPK cascade + 45
Path 2
Term Annotations click to browse term
  biological_process 19612
    biological regulation 13365
      regulation of biological process 12981
        signaling 7175
          signal transduction 6571
            regulation of signal transduction 3438
              regulation of intracellular signal transduction 2039
                regulation of stress-activated protein kinase signaling cascade 47
                  negative regulation of stress-activated protein kinase signaling cascade + 10
                  positive regulation of stress-activated protein kinase signaling cascade + 27
                  regulation of stress-activated MAPK cascade + 45
paths to the root