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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of interleukin-10 production
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Accession:GO:0032733 term browser browse the term
Definition:Any process that activates or increases the frequency, rate, or extent of interleukin-10 production.
Synonyms:exact_synonym: positive regulation of IL-10 production;   up regulation of interleukin-10 production;   upregulation of interleukin-10 production
 narrow_synonym: activation of interleukin-10 production;   positive regulation of interleukin-10 biosynthetic process;   positive regulation of interleukin-10 secretion;   stimulation of interleukin-10 production
 alt_id: GO:0045082;   GO:2001181


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positive regulation of interleukin-10 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl3 BCL3, transcription coactivator acts_upstream_of_or_within ISO (PMID:15465827) RGD PMID:15465827 NCBI chr 1:79,471,368...79,485,908
Ensembl chr 1:79,471,369...79,485,607 		JBrowse link
G Cd274 CD274 molecule involved_in ISO (PMID:10581077) RGD PMID:10581077 NCBI chr 1:227,116,674...227,137,379
Ensembl chr 1:227,116,649...227,134,450 		JBrowse link
G Cd28 Cd28 molecule involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:8617933)		 UniProt
Ensembl
RGD		 PMID:8617933 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:62,166,324...62,194,674
Ensembl chr 9:62,166,192...62,194,685 		JBrowse link
G Cd40lg CD40 ligand involved_in IDA
IEA
ISO		 GO_REF:0000107
(PMID:8617933)		 Ensembl
RGD		 PMID:8617933 PMID:18262271 GO_REF:0000107, RGD:2313421 NCBI chr  X:135,127,052...135,138,768
Ensembl chr  X:135,126,969...135,138,306 		JBrowse link
G Cd46 CD46 molecule involved_in ISO (PMID:12540904), (PMID:23086448) RGD PMID:12540904 PMID:23086448 NCBI chr13:106,575,586...106,606,325
Ensembl chr13:106,574,858...106,660,445 		JBrowse link
G Cd83 CD83 molecule acts_upstream_of_or_within ISO MGI:3055293 (PMID:15322158) RGD PMID:15322158 NCBI chr17:20,887,309...20,907,009
Ensembl chr17:20,887,309...20,907,083 		JBrowse link
G Clec7a C-type lectin domain containing 7A involved_in ISO (PMID:19358895)
(PMID:19136564)		 RGD PMID:19136564 PMID:19358895 NCBI chr 4:162,902,731...162,913,931
Ensembl chr 4:162,902,732...162,913,897 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISO
ISS		 (PMID:18453611)
GO_REF:0000024		 RGD
UniProt		 PMID:18453611 GO_REF:0000024 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226 		JBrowse link
G Fcer1g Fc epsilon receptor Ig acts_upstream_of_or_within ISO MGI:2384004 (PMID:11911824) RGD PMID:11911824 NCBI chr13:83,649,447...83,654,248
Ensembl chr13:83,649,449...83,671,443 		JBrowse link
G Gdnf glial cell derived neurotrophic factor IMP RGD PMID:32428552 RGD:405878062 NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209 		JBrowse link
G Hgf hepatocyte growth factor involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:21072211)		 Ensembl
RGD		 PMID:21072211 GO_REF:0000107 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409 		JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:22473704) RGD PMID:22473704 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 involved_in ISO (PMID:16148103) RGD PMID:16148103 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662 		JBrowse link
G Il12b interleukin 12B involved_in ISO (PMID:15265908) RGD PMID:15265908 NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903 		JBrowse link
G Il13 interleukin 13 involved_in ISO UniProtKB:P05112 (PMID:30634164) RGD PMID:30634164 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737 		JBrowse link
G Il20rb interleukin 20 receptor subunit beta acts_upstream_of_or_within ISO MGI:3830304 (PMID:19124723) RGD PMID:19124723 NCBI chr 8:100,979,085...101,010,829
Ensembl chr 8:100,980,383...101,009,942 		JBrowse link
G Il21 interleukin 21 acts_upstream_of_or_within ISO (PMID:14764669) RGD PMID:14764669 NCBI chr 2:120,117,105...120,127,012
Ensembl chr 2:120,119,444...120,126,996 		JBrowse link
G Il23a interleukin 23 subunit alpha involved_in ISO (PMID:15265908) RGD PMID:15265908 NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923 		JBrowse link
G Il4 interleukin 4 involved_in IDA
ISO		 UniProtKB:P35225 (PMID:30634164) RGD PMID:30634164 PMID:17125592 RGD:2317299 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il6 interleukin 6 involved_in ISO (PMID:31886314) RGD PMID:31886314 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Inava innate immunity activator involved_in ISO (PMID:28436939) RGD PMID:28436939 NCBI chr13:47,666,446...47,687,383
Ensembl chr13:47,666,447...47,686,729 		JBrowse link
G Irf4 interferon regulatory factor 4 involved_in ISO (PMID:12374808) RGD PMID:12374808 NCBI chr17:33,721,800...33,742,570
Ensembl chr17:33,721,811...33,740,070 		JBrowse link
G Isg15 ISG15 ubiquitin-like modifier involved_in ISO (PMID:29100055) RGD PMID:29100055 NCBI chr 5:166,784,148...166,785,435
Ensembl chr 5:166,784,148...166,785,435 		JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:16116184), (PMID:20209097)
(PMID:25065622)		 RGD PMID:16116184 PMID:20209097 PMID:25065622 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045 		JBrowse link
G Lilra5 leukocyte immunoglobulin like receptor A5 involved_in ISO (PMID:19009525) RGD PMID:19009525 NCBI chr 1:69,973,292...69,978,750
Ensembl chr 1:69,973,292...70,001,718 		JBrowse link
G Mir145 microRNA 145 acts_upstream_of ISO (PMID:30634164) RGD PMID:30634164 NCBI chr18:55,099,640...55,099,727
Ensembl chr18:55,099,640...55,099,727 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of ISO (PMID:21156799) RGD PMID:21156799 NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Pibf1 progesterone immunomodulatory binding factor 1 involved_in ISO (PMID:14634107) RGD PMID:14634107 NCBI chr15:75,850,389...76,019,711
Ensembl chr15:75,850,624...76,019,712 		JBrowse link
G Plcg2 phospholipase C, gamma 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:19136564), (PMID:22041900)		 Ensembl
RGD		 PMID:19136564 PMID:22041900 GO_REF:0000107 NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930 		JBrowse link
G Prkcz protein kinase C, zeta involved_in ISS
ISO		 GO_REF:0000024
(PMID:15987782)		 UniProt
RGD		 PMID:15987782 GO_REF:0000024 NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367 		JBrowse link
G Ptger4 prostaglandin E receptor 4 IMP RGD PMID:15560120 RGD:10043380 NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670 		JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO (PMID:16982856) RGD PMID:16982856 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Rad21 RAD21 cohesin complex component IMP RGD PMID:36538854 RGD:243065265 NCBI chr 7:83,287,867...83,314,810
Ensembl chr 7:83,287,870...83,314,817 		JBrowse link
G Rbm47 RNA binding motif protein 47 involved_in ISO (PMID:29844590) RGD PMID:29844590 NCBI chr14:42,053,290...42,191,572
Ensembl chr14:42,154,142...42,189,431 		JBrowse link
G Sash3 SAM and SH3 domain containing 3 acts_upstream_of_or_within ISO MGI:3716944 (PMID:16227612) RGD PMID:16227612 NCBI chr  X:127,326,815...127,341,521
Ensembl chr  X:127,326,859...127,341,519 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 involved_in ISO
IEA		 RNAcentral:URS00004E0808_9606|UniProtKB:P05231 (PMID:31886314)
GO_REF:0000107		 RGD
Ensembl		 PMID:31886314 GO_REF:0000107 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Syk spleen associated tyrosine kinase involved_in ISO
IEA		 (PMID:19358895)
GO_REF:0000107		 RGD
Ensembl		 PMID:19358895 GO_REF:0000107 NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410 		JBrowse link
G Tigit T cell immunoreceptor with Ig and ITIM domains involved_in ISO
IBA		 (PMID:19011627)
GO_REF:0000033		 RGD
GO_Central		 PMID:19011627 GO_REF:0000033 NCBI chr11:57,029,024...57,046,627
Ensembl chr11:57,029,118...57,045,994 		JBrowse link
G Tlr2 toll-like receptor 2 IDA RGD PMID:22653369 RGD:7241093 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tlr4 toll-like receptor 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:15356140)
(PMID:21609717)		 Ensembl
RGD		 PMID:15356140 PMID:21609717 GO_REF:0000107 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tlr9 toll-like receptor 9 involved_in ISO (PMID:15356140) RGD PMID:15356140 NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796 		JBrowse link
G Tnfsf18 TNF superfamily member 18 NOT|involved_in ISO (PMID:24107315) RGD PMID:24107315 NCBI chr13:73,833,478...73,907,249
Ensembl chr13:73,831,252...73,843,169 		JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (PMID:20844189) RGD PMID:20844189 NCBI chr13:73,723,329...73,746,809
Ensembl chr13:73,723,329...73,746,788 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:28592261) RGD PMID:28592261 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
G Tslp thymic stromal lymphopoietin involved_in ISO
IBA		 (PMID:17242164)
GO_REF:0000033		 RGD
GO_Central		 PMID:17242164 GO_REF:0000033 NCBI chr18:24,447,409...24,454,244
Ensembl chr18:24,449,844...24,453,548 		JBrowse link
G Tusc2 tumor suppressor 2, mitochondrial calcium regulator acts_upstream_of_or_within ISO MGI:3706236 (PMID:24042119) RGD PMID:24042119 NCBI chr 8:108,236,838...108,240,056
Ensembl chr 8:108,236,838...108,240,056 		JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (PMID:18832695) RGD PMID:18832695 NCBI chr13:77,248,687...77,252,343
Ensembl chr13:77,248,717...77,252,329 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20069
    positive regulation of biological process 6746
      positive regulation of multicellular organismal process 1895
        positive regulation of cytokine production 535
          positive regulation of interleukin-10 production 47
Path 2
Term Annotations click to browse term
  biological_process 20069
    biological regulation 13554
      regulation of biological process 13131
        regulation of cellular process 12768
          regulation of metabolic process 6743
            regulation of biosynthetic process 5507
              regulation of macromolecule biosynthetic process 5305
                regulation of gene expression 5186
                  regulation of cytokine production 906
                    positive regulation of cytokine production 535
                      positive regulation of interleukin-10 production 47
paths to the root