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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of cell-substrate adhesion
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Accession:GO:0010812 term browser browse the term
Definition:Any process that decreases the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules.



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negative regulation of cell-substrate adhesion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angpt2 angiopoietin 2 acts_upstream_of_or_within IDA (PMID:9846489) MGI PMID:9846489 NCBI chr 8:18,740,279...18,791,578
Ensembl chr 8:18,740,279...18,791,578
JBrowse link
G Col1a1 collagen, type I, alpha 1 acts_upstream_of_or_within IDA (PMID:17018525) MGI PMID:17018525 NCBI chr11:94,827,050...94,843,868
Ensembl chr11:94,827,050...94,843,868
JBrowse link
G Coro2b coronin, actin binding protein, 2B acts_upstream_of_or_within ISO (PMID:29162887) MGI PMID:29162887 NCBI chr 9:62,326,770...62,444,326
Ensembl chr 9:62,326,774...62,444,326
JBrowse link
G Dmtn dematin actin binding protein involved_in IMP (PMID:18505823) UniProt PMID:18505823 NCBI chr14:70,839,624...70,873,488
Ensembl chr14:70,838,703...70,873,418
JBrowse link
G Fzd4 frizzled class receptor 4 involved_in ISO
IMP
(PMID:18156211) GO_Central
BHF-UCL
PMID:18156211 GO_REF:0000119 NCBI chr 7:89,053,574...89,062,341
Ensembl chr 7:89,053,563...89,062,342
JBrowse link
G Fzd7 frizzled class receptor 7 involved_in IMP
ISO
(PMID:18156211) BHF-UCL
GO_Central
PMID:18156211 GO_REF:0000119 NCBI chr 1:59,521,306...59,526,114
Ensembl chr 1:59,521,583...59,526,114
JBrowse link
G Gcnt2 glucosaminyl (N-acetyl) transferase 2 (I blood group) involved_in ISO GO_Central GO_REF:0000119 NCBI chr13:41,013,417...41,114,368
Ensembl chr13:41,013,230...41,114,368
JBrowse link
G Lgals1 lectin, galactose binding, soluble 1 involved_in ISO RGD
GO_Central
PMID:1955484 GO_REF:0000096 RGD:2316546 NCBI chr15:78,810,925...78,814,665
Ensembl chr15:78,810,925...78,814,665
JBrowse link
G Lrp1 low density lipoprotein receptor-related protein 1 involved_in ISO RGD
GO_Central
PMID:20197276 GO_REF:0000096 RGD:13800550 NCBI chr10:127,374,026...127,457,158
Ensembl chr10:127,374,030...127,457,017
JBrowse link
G Men1 multiple endocrine neoplasia 1 involved_in ISO RGD
GO_Central
PMID:15054094 GO_REF:0000096 RGD:1304318 NCBI chr19:6,385,009...6,390,924
Ensembl chr19:6,385,009...6,390,921
JBrowse link
G Mir183 microRNA 183 acts_upstream_of ISO (PMID:19940135) ARUK-UCL PMID:19940135 NCBI chr 6:30,169,667...30,169,736
Ensembl chr 6:30,169,667...30,169,736
JBrowse link
G Mir503 microRNA 503 involved_in ISO (PMID:21220732) BHF-UCL PMID:21220732 NCBI chr  X:52,142,861...52,142,931
Ensembl chr  X:52,142,861...52,142,931
JBrowse link
G Muc21 mucin 21 acts_upstream_of_or_within IDA (PMID:20388707) MGI PMID:20388707 NCBI chr17:35,928,815...35,937,529
Ensembl chr17:35,928,815...35,937,529
JBrowse link
G Notch1 notch 1 involved_in IEA
ISO
Ensembl
GO_Central
GO_REF:0000107 GO_REF:0000119 NCBI chr 2:26,347,914...26,393,834
Ensembl chr 2:26,347,915...26,406,675
JBrowse link
G Plg plasminogen involved_in ISO GO_Central GO_REF:0000119 NCBI chr17:12,597,496...12,638,271
Ensembl chr17:12,597,495...12,638,272
JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 involved_in ISO
IEA
RGD
GO_Central
Ensembl
PMID:10484424 GO_REF:0000096 GO_REF:0000107 RGD:401965470 NCBI chr 2:167,772,670...167,821,305
Ensembl chr 2:167,773,977...167,821,305
JBrowse link
G Ptprz1 protein tyrosine phosphatase receptor type Z, polypeptide 1 involved_in ISO RGD
GO_Central
PMID:12821372 GO_REF:0000096 RGD:9589826 NCBI chr 6:22,875,302...23,052,915
Ensembl chr 6:22,875,501...23,052,915
JBrowse link
G Rhoa ras homolog family member A involved_in IMP (PMID:18981818) ARUK-UCL PMID:18981818 NCBI chr 9:108,183,359...108,215,142
Ensembl chr 9:108,183,328...108,215,133
JBrowse link
G Spock1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1 involved_in ISO
ISS
GO_Central
UniProt
GO_REF:0000024 GO_REF:0000119 NCBI chr13:57,569,008...58,056,194
Ensembl chr13:57,569,008...58,056,146
JBrowse link
G Tbcd tubulin-specific chaperone d involved_in ISS UniProt GO_REF:0000024 NCBI chr11:121,342,817...121,507,996
Ensembl chr11:121,342,775...121,507,990
JBrowse link
G Wnt1 wingless-type MMTV integration site family, member 1 involved_in ISO
IEA
GO_Central
Ensembl
GO_REF:0000107 GO_REF:0000119 NCBI chr15:98,687,738...98,691,711
Ensembl chr15:98,687,738...98,691,718
JBrowse link
negative regulation of cell-matrix adhesion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acer2 alkaline ceramidase 2 involved_in IEA
ISO
Ensembl
GO_Central
GO_REF:0000107 GO_REF:0000119 NCBI chr 4:86,792,585...86,853,059
Ensembl chr 4:86,792,633...86,853,059
JBrowse link
G Adam15 ADAM metallopeptidase domain 15 involved_in IEA
ISO
Ensembl
GO_Central
GO_REF:0000107 GO_REF:0000119 NCBI chr 3:89,246,947...89,257,589
Ensembl chr 3:89,245,849...89,257,303
JBrowse link
G Ajap1 adherens junction associated protein 1 involved_in IEA
ISO
Ensembl
GO_Central
GO_REF:0000107 GO_REF:0000119 NCBI chr 4:153,457,678...153,568,313
Ensembl chr 4:153,457,678...153,567,268
JBrowse link
G Bcl6 B cell leukemia/lymphoma 6 acts_upstream_of_or_within IMP (PMID:15860730) MGI PMID:15860730 NCBI chr16:23,780,058...23,807,602
Ensembl chr16:23,783,802...23,807,602
JBrowse link
G Cask calcium/calmodulin dependent serine protein kinase involved_in ISO
IEA
GO_Central
Ensembl
GO_REF:0000107 GO_REF:0000119 NCBI chr  X:13,383,319...13,713,020
Ensembl chr  X:13,383,319...13,717,606
JBrowse link
G Cdkn2a cyclin dependent kinase inhibitor 2A involved_in ISO GO_Central GO_REF:0000119 NCBI chr 4:89,192,710...89,212,856
Ensembl chr 4:89,192,708...89,212,890
JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 involved_in ISO RGD
GO_Central
PMID:12837632 GO_REF:0000096 RGD:1299196 NCBI chr15:54,702,297...54,816,284
Ensembl chr15:54,702,297...54,816,288
JBrowse link
G Hoxa7 homeobox A7 involved_in IEA
ISO
Ensembl
GO_Central
GO_REF:0000107 GO_REF:0000119 NCBI chr 6:52,191,471...52,198,757
Ensembl chr 6:52,191,471...52,198,834
JBrowse link
G Jag1 jagged 1 involved_in IEA
ISO
Ensembl
GO_Central
GO_REF:0000107 GO_REF:0000119 NCBI chr 2:136,923,371...136,958,440
Ensembl chr 2:136,923,376...136,958,564
JBrowse link
G Mir192 microRNA 192 involved_in ISO (PMID:26506238) ARUK-UCL PMID:26506238 NCBI chr19:6,314,874...6,314,962
Ensembl chr19:6,314,874...6,314,962
JBrowse link
G Mir29c microRNA 29c involved_in ISO (PMID:23936390) BHF-UCL PMID:23936390 NCBI chr 1:194,719,855...194,719,942
Ensembl chr 1:194,719,855...194,719,942
JBrowse link
G Muc4 mucin 4 involved_in ISO RGD
GO_Central
PMID:9407114 GO_REF:0000096 RGD:2303753 NCBI chr16:32,555,089...32,602,786
Ensembl chr16:32,555,015...32,602,754
JBrowse link
G Myoc myocilin involved_in ISO
ISS
GO_Central
UniProt
GO_REF:0000024 GO_REF:0000119 NCBI chr 1:162,466,719...162,477,263
Ensembl chr 1:162,466,724...162,477,262
JBrowse link
G Nexmif neurite extension and migration factor involved_in ISO
IEA
IBA
RGD
GO_Central
Ensembl
PMID:24071057 GO_REF:0000033 GO_REF:0000096 GO_REF:0000107 RGD:13442493 NCBI chr  X:103,120,367...103,245,403
Ensembl chr  X:103,121,040...103,244,791
JBrowse link
G Nf1 neurofibromin 1 acts_upstream_of_or_within IGI (PMID:17053831) MGI PMID:17053831 NCBI chr11:79,223,541...79,472,435
Ensembl chr11:79,230,519...79,472,438
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 acts_upstream_of_or_within IGI (PMID:17053831) MGI PMID:17053831 NCBI chr13:101,817,269...101,904,725
Ensembl chr13:101,817,071...101,904,725
JBrowse link
G Plet1 placenta expressed transcript 1 involved_in IBA
IMP
(PMID:20130590) GO_Central
UniProt
PMID:20130590 GO_REF:0000033 NCBI chr 9:50,405,825...50,416,939
Ensembl chr 9:50,405,825...50,416,782
JBrowse link
G Postn periostin, osteoblast specific factor involved_in ISO
IEA
RGD
Ensembl
GO_Central
PMID:15381649 GO_REF:0000096 GO_REF:0000107 RGD:10040999 NCBI chr 3:54,266,688...54,298,462
Ensembl chr 3:54,268,530...54,298,458
JBrowse link
G Rasa1 RAS p21 protein activator 1 involved_in ISO GO_Central GO_REF:0000119 NCBI chr13:85,362,893...85,437,487
Ensembl chr13:85,362,899...85,437,249
JBrowse link
G Sema3e sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E involved_in IMP (PMID:20385769) UniProt PMID:20385769 NCBI chr 5:14,075,290...14,306,703
Ensembl chr 5:14,075,290...14,306,703
JBrowse link
G Thbs1 thrombospondin 1 acts_upstream_of_or_within
involved_in
ISO (PMID:16150726) MGI
GO_Central
PMID:16150726 GO_REF:0000119 NCBI chr 2:117,942,357...117,957,614
Ensembl chr 2:117,942,357...117,957,614
JBrowse link
negative regulation of endothelial cell-matrix adhesion via fibronectin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir92-1 microRNA 92-1 involved_in ISO (PMID:19460962) BHF-UCL PMID:19460962 NCBI chr14:115,281,859...115,281,938
Ensembl chr14:115,281,859...115,281,938
JBrowse link
G Mir92-2 microRNA 92-2 involved_in ISO (PMID:19460962) BHF-UCL PMID:19460962 NCBI chr  X:51,830,715...51,830,805
Ensembl chr  X:51,830,715...51,830,805
JBrowse link
G Mmp12 matrix metallopeptidase 12 involved_in ISO
IEA
GO_Central
Ensembl
GO_REF:0000107 GO_REF:0000119 NCBI chr 9:7,344,397...7,360,461
Ensembl chr 9:7,344,381...7,369,499
JBrowse link
negative regulation of focal adhesion assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvrl1 activin A receptor, type II-like 1 involved_in ISO
IEA
GO_Central
Ensembl
GO_REF:0000107 GO_REF:0000119 NCBI chr15:101,026,403...101,043,217
Ensembl chr15:101,026,403...101,043,217
JBrowse link
G Apod apolipoprotein D involved_in ISS
ISO
UniProt
GO_Central
GO_REF:0000024 GO_REF:0000119 NCBI chr16:31,115,010...31,133,626
Ensembl chr16:31,115,010...31,133,626
JBrowse link
G Arhgap6 Rho GTPase activating protein 6 involved_in IEA
ISO
Ensembl
GO_Central
GO_REF:0000107 GO_REF:0000119 NCBI chr  X:167,578,091...168,087,436
Ensembl chr  X:167,578,095...168,087,431
JBrowse link
G Clasp2 CLIP associating protein 2 involved_in ISO GO_Central GO_REF:0000119 NCBI chr 9:113,567,776...113,748,765
Ensembl chr 9:113,570,541...113,748,750
JBrowse link
G Coro1c coronin, actin binding protein 1C involved_in ISO
IEA
GO_Central
Ensembl
GO_REF:0000107 GO_REF:0000119 NCBI chr 5:113,980,500...114,046,767
Ensembl chr 5:113,980,497...114,046,819
JBrowse link
G Dlc1 deleted in liver cancer 1 involved_in ISO GO_Central GO_REF:0000119 NCBI chr 8:37,034,893...37,420,343
Ensembl chr 8:37,034,905...37,420,297
JBrowse link
G Dmtn dematin actin binding protein involved_in IMP (PMID:18505823) UniProt PMID:18505823 NCBI chr14:70,839,624...70,873,488
Ensembl chr14:70,838,703...70,873,418
JBrowse link
G Dusp22 dual specificity phosphatase 22 involved_in IEA
ISO
Ensembl
GO_Central
GO_REF:0000107 GO_REF:0000119 NCBI chr13:30,844,042...30,895,215
Ensembl chr13:30,843,982...30,895,214
JBrowse link
G Fam107a family with sequence similarity 107, member A involved_in ISS
ISO
UniProt
GO_Central
GO_REF:0000024 GO_REF:0000119 NCBI chr14:14,152,166...14,173,503
Ensembl chr14:14,151,750...14,173,499
JBrowse link
G Itgb1bp1 integrin beta 1 binding protein 1 involved_in IBA
ISO
IMP
(PMID:18227284) GO_Central
UniProt
PMID:18227284 GO_REF:0000033 GO_REF:0000119 NCBI chr12:21,317,247...21,336,285
Ensembl chr12:21,290,826...21,336,285
JBrowse link
G Lrp1 low density lipoprotein receptor-related protein 1 involved_in ISO RGD
GO_Central
PMID:20197276 GO_REF:0000096 RGD:13800550 NCBI chr10:127,374,026...127,457,158
Ensembl chr10:127,374,030...127,457,017
JBrowse link
G Mmp14 matrix metallopeptidase 14 (membrane-inserted) involved_in ISO
IEA
RGD
Ensembl
GO_Central
PMID:15044209 GO_REF:0000096 GO_REF:0000107 RGD:1582604 NCBI chr14:54,669,055...54,679,913
Ensembl chr14:54,669,069...54,682,821
JBrowse link
G Phldb2 pleckstrin homology like domain, family B, member 2 involved_in IEA
ISO
Ensembl
GO_Central
GO_REF:0000107 GO_REF:0000119 NCBI chr16:45,566,593...45,773,961
Ensembl chr16:45,566,606...45,773,961
JBrowse link
G Pten phosphatase and tensin homolog involved_in ISO
ISS
GO_Central
UniProt
GO_REF:0000024 GO_REF:0000119 NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560
JBrowse link
G Rcc2 regulator of chromosome condensation 2 involved_in IMP (PMID:19738201) UniProt PMID:19738201 NCBI chr 4:140,427,308...140,450,531
Ensembl chr 4:140,427,852...140,450,531
JBrowse link
G Src Rous sarcoma oncogene involved_in ISO
IEA
GO_Central
Ensembl
GO_REF:0000096 GO_REF:0000107 NCBI chr 2:157,265,828...157,313,758
Ensembl chr 2:157,260,364...157,313,782
JBrowse link
negative regulation of smooth muscle cell-matrix adhesion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apod apolipoprotein D involved_in ISS
ISO
UniProt
GO_Central
GO_REF:0000024 GO_REF:0000119 NCBI chr16:31,115,010...31,133,626
Ensembl chr16:31,115,010...31,133,626
JBrowse link
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 involved_in ISO GO_Central GO_REF:0000119 NCBI chr 5:137,090,358...137,101,126
Ensembl chr 5:137,090,358...137,101,122
JBrowse link
negative regulation of substrate adhesion-dependent cell spreading term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn4 actinin alpha 4 involved_in ISO GO_Central GO_REF:0000119 NCBI chr 7:28,592,673...28,661,799
Ensembl chr 7:28,592,673...28,661,765
JBrowse link
G Ap1ar adaptor-related protein complex 1 associated regulatory protein acts_upstream_of_or_within IMP
ISO
(PMID:22689987) MGI PMID:22689987 GO_REF:0000008 NCBI chr 3:127,600,656...127,631,148
Ensembl chr 3:127,600,656...127,631,172
JBrowse link
G Bcar1 breast cancer anti-estrogen resistance 1 involved_in ISO RGD
GO_Central
PMID:15817476 GO_REF:0000096 RGD:7488898 NCBI chr 8:112,437,106...112,470,481
Ensembl chr 8:112,437,106...112,470,441
JBrowse link
G Coro1c coronin, actin binding protein 1C involved_in ISO
IEA
GO_Central
Ensembl
GO_REF:0000107 GO_REF:0000119 NCBI chr 5:113,980,500...114,046,767
Ensembl chr 5:113,980,497...114,046,819
JBrowse link
G Dmtn dematin actin binding protein involved_in IMP (PMID:18505823) UniProt PMID:18505823 NCBI chr14:70,839,624...70,873,488
Ensembl chr14:70,838,703...70,873,418
JBrowse link
G Efna5 ephrin A5 acts_upstream_of_or_within ISO (PMID:23242526) MGI PMID:23242526 NCBI chr17:62,909,949...63,188,431
Ensembl chr17:62,911,179...63,188,312
JBrowse link
G Fbln1 fibulin 1 involved_in IEA
ISO
Ensembl
GO_Central
GO_REF:0000107 GO_REF:0000119 NCBI chr15:85,090,150...85,170,495
Ensembl chr15:85,090,150...85,170,736
JBrowse link
G Gbp2b guanylate binding protein 2b involved_in ISO (PMID:24337748) UniProt PMID:24337748 NCBI chr 3:142,300,577...142,324,940
Ensembl chr 3:142,300,608...142,324,940
JBrowse link
G Itgb1bp1 integrin beta 1 binding protein 1 involved_in ISS
IDA
ISO
IBA
(PMID:18227284) UniProt
GO_Central
PMID:18227284 GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 NCBI chr12:21,317,247...21,336,285
Ensembl chr12:21,290,826...21,336,285
JBrowse link
G Kank1 KN motif and ankyrin repeat domains 1 involved_in ISO GO_Central GO_REF:0000119 NCBI chr19:25,214,146...25,411,861
Ensembl chr19:25,214,339...25,411,860
JBrowse link
G Meltf melanotransferrin involved_in ISO
IEA
GO_Central
Ensembl
GO_REF:0000107 GO_REF:0000119 NCBI chr16:31,697,449...31,717,838
Ensembl chr16:31,697,628...31,717,838
JBrowse link
G Postn periostin, osteoblast specific factor involved_in ISO
IEA
RGD
Ensembl
GO_Central
PMID:15381649 GO_REF:0000096 GO_REF:0000107 RGD:10040999 NCBI chr 3:54,266,688...54,298,462
Ensembl chr 3:54,268,530...54,298,458
JBrowse link
G Rcc2 regulator of chromosome condensation 2 involved_in IMP (PMID:19738201) UniProt PMID:19738201 NCBI chr 4:140,427,308...140,450,531
Ensembl chr 4:140,427,852...140,450,531
JBrowse link
G Spry4 sprouty RTK signaling antagonist 4 involved_in ISS
ISO
UniProt
GO_Central
GO_REF:0000024 GO_REF:0000119 NCBI chr18:38,719,300...38,734,400
Ensembl chr18:38,719,300...38,734,468
JBrowse link
G Tacstd2 tumor-associated calcium signal transducer 2 involved_in IDA (PMID:22194864) UniProt PMID:22194864 NCBI chr 6:67,511,043...67,512,806
Ensembl chr 6:67,511,046...67,512,780
JBrowse link

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