Spry4 (sprouty RTK signaling antagonist 4) - Rat Genome Database

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Gene: Spry4 (sprouty RTK signaling antagonist 4) Mus musculus
Analyze
Symbol: Spry4
Name: sprouty RTK signaling antagonist 4
RGD ID: 1313287
MGI Page MGI
Description: Predicted to enable protein kinase inhibitor activity. Acts upstream of or within cellular response to leukemia inhibitory factor and negative regulation of MAP kinase activity. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Is expressed in several structures, including alimentary system; embryo mesenchyme; genitourinary system; germ layer; and nervous system. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 17 with or without anosmia. Orthologous to human SPRY4 (sprouty RTK signaling antagonist 4).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: A030006O18Rik; spro; sprouty homolog 4; sprouty homolog 4 (Drosophila); sprouty4; spry-4
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391838,719,300 - 38,734,400 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1838,719,300 - 38,734,468 (-)EnsemblGRCm39 Ensembl
GRCm381838,586,247 - 38,601,347 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1838,586,247 - 38,601,415 (-)EnsemblGRCm38mm10GRCm38
MGSCv371838,745,919 - 38,760,922 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361838,712,239 - 38,727,242 (-)NCBIMGSCv36mm8
Celera1839,928,878 - 39,943,870 (-)NCBICelera
Cytogenetic Map18B3NCBI
cM Map1820.5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,3',4,4'-tetrachlorobiphenyl  (EXP)
3,3',5,5'-tetrabromobisphenol A  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxyphenyl retinamide  (EXP)
6-propyl-2-thiouracil  (ISO)
acrolein  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (EXP,ISO)
alpha-pinene  (ISO)
amitrole  (ISO)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
atrazine  (ISO)
azathioprine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-lapachone  (ISO)
bis(2-chloroethyl) sulfide  (EXP)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP,ISO)
C60 fullerene  (ISO)
caffeine  (ISO)
carbon nanotube  (EXP,ISO)
chloroprene  (EXP)
chlorpyrifos  (EXP)
cisplatin  (ISO)
clobetasol  (EXP)
cocaine  (ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
dibutyl phthalate  (EXP,ISO)
dichloroacetic acid  (EXP)
diclofenac  (EXP)
dicrotophos  (ISO)
dimethylarsinic acid  (EXP)
dioxygen  (EXP,ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
fluoranthene  (EXP)
folic acid  (EXP,ISO)
formaldehyde  (ISO)
FR900359  (ISO)
gentamycin  (ISO)
glycidol  (ISO)
hydrogen peroxide  (ISO)
hydroquinone  (ISO)
indometacin  (ISO)
ivermectin  (ISO)
lead diacetate  (ISO)
leflunomide  (ISO)
Licochalcone B  (ISO)
manganese(II) chloride  (ISO)
menadione  (ISO)
mercury dibromide  (ISO)
methimazole  (ISO)
methotrexate  (EXP)
methylarsonic acid  (EXP)
methylisothiazolinone  (ISO)
methylmercury chloride  (ISO)
mono(2-ethylhexyl) phthalate  (EXP,ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-Nitrosopyrrolidine  (ISO)
nitrofen  (ISO)
ozone  (EXP,ISO)
paracetamol  (ISO)
PCB138  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (EXP)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (ISO)
propiconazole  (EXP)
rotenone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (EXP,ISO)
silver(0)  (EXP,ISO)
sodium arsenate  (EXP)
sodium arsenite  (EXP,ISO)
sulfadimethoxine  (ISO)
sulforaphane  (ISO)
tert-butyl hydroperoxide  (ISO)
Theaflavin 3,3'-digallate  (ISO)
thioacetamide  (ISO)
thiram  (ISO)
tricetin  (ISO)
triclosan  (ISO)
triptonide  (EXP)
troglitazone  (EXP)
urethane  (ISO)
ursodeoxycholic acid  (ISO)
valproic acid  (EXP,ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (ISO,ISS)
cytosol  (IBA)
ruffle membrane  (IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. MGD IEA MGD IEA
3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. Mouse MP Annotation Import Pipeline RGD automated import pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10330503   PMID:10349636   PMID:10498682   PMID:10512203   PMID:10769235   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11238463   PMID:11731251   PMID:12117807  
PMID:12152071   PMID:12477932   PMID:12520002   PMID:12781690   PMID:12904583   PMID:14610273   PMID:15136142   PMID:15489334   PMID:15729686   PMID:15840001   PMID:16120640   PMID:16141072  
PMID:16141073   PMID:16172976   PMID:16339969   PMID:16651541   PMID:16877379   PMID:16884697   PMID:16888801   PMID:16890158   PMID:16989802   PMID:17156747   PMID:17181553   PMID:17369402  
PMID:17681139   PMID:17967808   PMID:17974561   PMID:18077585   PMID:18231602   PMID:18337453   PMID:18582454   PMID:18594511   PMID:18799693   PMID:19097117   PMID:19101957   PMID:19233155  
PMID:19304889   PMID:19424491   PMID:19440349   PMID:19453770   PMID:19493272   PMID:19592577   PMID:19783740   PMID:19864314   PMID:19913006   PMID:20105280   PMID:20348033   PMID:20439489  
PMID:20719962   PMID:20826535   PMID:20934536   PMID:20962035   PMID:21143873   PMID:21240919   PMID:21267068   PMID:21368122   PMID:21471156   PMID:21655085   PMID:21693512   PMID:21743007  
PMID:21784065   PMID:21806977   PMID:21839920   PMID:21862563   PMID:21873635   PMID:22465667   PMID:22484060   PMID:22537490   PMID:22629441   PMID:22632802   PMID:22674535   PMID:22675207  
PMID:23074222   PMID:23123965   PMID:23293290   PMID:23606267   PMID:23633963   PMID:23643382   PMID:23955631   PMID:24055172   PMID:24361260   PMID:24732356   PMID:25034710   PMID:25152336  
PMID:25446535   PMID:25541251   PMID:25813538   PMID:25822087   PMID:25897685   PMID:25923139   PMID:26291313   PMID:26362256   PMID:26540287   PMID:26655476   PMID:26702830   PMID:26813283  
PMID:26984772   PMID:27046834   PMID:27130872   PMID:27436040   PMID:27770432   PMID:27827819   PMID:27894818   PMID:28027321   PMID:28280213   PMID:28489004   PMID:28644741   PMID:28705898  
PMID:28732181   PMID:28893950   PMID:29213092   PMID:29964027   PMID:30566624   PMID:31291246   PMID:31896583   PMID:32421711   PMID:32452519   PMID:32492250   PMID:33210601   PMID:33929320  
PMID:34184730   PMID:34321999   PMID:34423857   PMID:34895467   PMID:35297995   PMID:35729116   PMID:36334381   PMID:37222910   PMID:38355793   PMID:38466355   PMID:39174793  


Genomics

Comparative Map Data
Spry4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391838,719,300 - 38,734,400 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1838,719,300 - 38,734,468 (-)EnsemblGRCm39 Ensembl
GRCm381838,586,247 - 38,601,347 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1838,586,247 - 38,601,415 (-)EnsemblGRCm38mm10GRCm38
MGSCv371838,745,919 - 38,760,922 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361838,712,239 - 38,727,242 (-)NCBIMGSCv36mm8
Celera1839,928,878 - 39,943,870 (-)NCBICelera
Cytogenetic Map18B3NCBI
cM Map1820.5NCBI
SPRY4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385142,310,430 - 142,325,021 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5142,310,427 - 142,326,455 (-)EnsemblGRCh38hg38GRCh38
GRCh375141,689,995 - 141,704,586 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365141,670,189 - 141,684,750 (-)NCBINCBI36Build 36hg18NCBI36
Build 345141,670,190 - 141,684,750NCBI
Celera5137,771,260 - 137,785,910 (-)NCBICelera
Cytogenetic Map5q31.3NCBI
HuRef5136,836,448 - 136,851,092 (-)NCBIHuRef
CHM1_15141,123,564 - 141,138,189 (-)NCBICHM1_1
T2T-CHM13v2.05142,841,037 - 142,855,632 (-)NCBIT2T-CHM13v2.0
Spry4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81830,687,633 - 30,702,546 (-)NCBIGRCr8
mRatBN7.21830,436,513 - 30,451,426 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1830,436,443 - 30,453,004 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1830,540,734 - 30,555,640 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01831,301,144 - 31,316,041 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01830,636,445 - 30,651,342 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01832,593,370 - 32,609,890 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1832,594,958 - 32,609,864 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01832,271,207 - 32,287,673 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41831,532,680 - 31,547,586 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11831,561,542 - 31,563,842 (-)NCBI
Celera1830,074,673 - 30,089,579 (-)NCBICelera
Cytogenetic Map18p11NCBI
Spry4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495541511,489,439 - 11,504,247 (+)NCBIChiLan1.0ChiLan1.0
SPRY4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24137,555,079 - 137,569,735 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15135,694,633 - 135,709,294 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05137,667,280 - 137,683,578 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15143,778,785 - 143,793,518 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5143,778,785 - 143,791,939 (-)Ensemblpanpan1.1panPan2
SPRY4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1237,199,890 - 37,213,710 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl237,203,609 - 37,208,858 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha234,251,922 - 34,265,782 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0237,655,748 - 37,669,607 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl237,655,756 - 37,669,556 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1234,729,962 - 34,743,810 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0235,546,901 - 35,560,761 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0236,348,824 - 36,362,690 (-)NCBIUU_Cfam_GSD_1.0
Spry4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213150,333,698 - 150,348,542 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650411,907,681 - 11,922,469 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493650411,907,667 - 11,922,487 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SPRY4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2143,875,355 - 143,892,292 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12143,877,334 - 143,891,280 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22150,062,423 - 150,076,497 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SPRY4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12344,931,967 - 44,946,838 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603432,902,675 - 32,917,563 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Spry4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247741,508,315 - 1,523,456 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Spry4
565 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1716
Count of miRNA genes:692
Interacting mature miRNAs:883
Transcripts:ENSMUST00000025295
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1558743Kcal1_mkilocalorie 1 (mouse)Not determined181901887453018992Mouse
1302163Bmd16_mbone mineral density 16 (mouse)Not determined182966791463668060Mouse
11532716Sluc41c_msusceptibility to lung cancer 41c (mouse)182261991456620127Mouse
11532715Sluc41b_msusceptibility to lung cancer 41b (mouse)182261991456620127Mouse
11041903Lmr27_mleishmaniasis resistance 27 (mouse)183618756745109518Mouse
11532710Sluc41a_msusceptibility to lung cancer 41a (mouse)182261991456620127Mouse
25823171Hrsq10_mhost response to SARS QTL 10, D4% weight (mouse)182724111558827077Mouse
11532709Sluc41_msusceptibility to lung cancer 41 (mouse)182095369457590708Mouse
1301400Lmr13_mleishmaniasis resistance 13 (mouse)Not determined182810938062109518Mouse
25823174Hrsq11_mhost response to SARS QTL 11, log titer (mouse)182724111558827077Mouse
1300638Im7_mimmunoregulatory 7 (mouse)Not determined181901887453018992Mouse
1558873Hrtfm7_mheart failure modifier 7 (mouse)Not determined18808696442087106Mouse
25823173Hrsq12_mhost response to SARS QTL 12, hemorrhage (mouse)182489588178339555Mouse
1300994Pvcan3_mprotection against vaginal candidiasis 3 (mouse)Not determined181619964050199776Mouse
1301570Sluc14_msusceptibility to lung cancer 14 (mouse)Not determined182261991456620127Mouse
13504732Cath6_mcarotid atherosclerosis 6 (mouse)181363712647637126Mouse
1558849W3q15_mweight 3 weeks QTL 15 (mouse)Not determined18504111961272643Mouse
12880412V125Dq12_mvitamin D active form serum level QTL 12 (mouse)183023306764233067Mouse
1301771Pcyts6_mplasmacytoma susceptibility 6 (mouse)Not determined183565863269658851Mouse
1300877Adip8_madiposity 8 (mouse)Not determined182261991456620127Mouse
4141857Mhysq5_mmale hybrid sterility QTL 5 (mouse)Not determined2813060462130739Mouse
1300685Scc5_mcolon tumor susceptibility 5 (mouse)Not determined183198848065988629Mouse
4142366Chlq10_mcirculating hormone level QTL 10 (mouse)Not determined183629102270291180Mouse
1301307Phospq1_mphospholipid QTL 1 (mouse)Not determined181813970452139859Mouse
1357690Vtbt19_mvertebral trabecular bone trait 19 (mouse)Not determined183309104367091221Mouse
4142031Moen1_mmodifier of engrailed QTL 1 (mouse)Not determined182411556058115730Mouse
15039381Ltgq8_mliver triglyceride QTL 8 (mouse)183820656972206569Mouse
12904950Smmq3_msoleus muscle mass QTL 3 (mouse)182605687560056875Mouse
15039383Mvlq5_mmicrovesicular liver lesion QTL 5 (mouse)183820656972206569Mouse
25823167Hrsq5_mhost response to SARS QTL 5, D3% weight (mouse)182724111558827077Mouse
1357603Mom3_mmodifier of Min 3 (mouse)Not determined181403002367098962Mouse
13463476Hctq8_mhematocrit QTL 8 (mouse)182121758055217727Mouse
27226723Tibw9_mtibia width 9, proximal, 16 week (mouse)18320000060933072Mouse
15039384Liviq1_mliver inflammation QTL 1 (mouse)183820656972206569Mouse
15039386Mvlq4_mmacrovesicular liver lesion QTL 4 (mouse)183820656972206569Mouse

Markers in Region
Spry4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map18B3UniSTS
cM Map1820.5UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000025295   ⟹   ENSMUSP00000025295
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1838,719,300 - 38,734,468 (-)Ensembl
GRCm38.p6 Ensembl1838,586,247 - 38,601,415 (-)Ensembl
RefSeq Acc Id: NM_011898   ⟹   NP_036028
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391838,719,300 - 38,734,400 (-)NCBI
GRCm381838,586,247 - 38,601,347 (-)NCBI
MGSCv371838,745,919 - 38,760,922 (-)RGD
Celera1839,928,878 - 39,943,870 (-)RGD
cM Map18 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_036161148   ⟹   XP_036017041
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391838,719,300 - 38,732,049 (-)NCBI
Sequence:
RefSeq Acc Id: NP_036028   ⟸   NM_011898
- UniProtKB: Q543R1 (UniProtKB/Swiss-Prot),   Q9QXV7 (UniProtKB/Swiss-Prot),   Q9WTP2 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000025295   ⟸   ENSMUST00000025295
RefSeq Acc Id: XP_036017041   ⟸   XM_036161148
- Peptide Label: isoform X1
- UniProtKB: Q9WTP2 (UniProtKB/Swiss-Prot),   Q543R1 (UniProtKB/Swiss-Prot),   Q9QXV7 (UniProtKB/Swiss-Prot)
Protein Domains
SPR

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9WTP2-F1-model_v2 AlphaFold Q9WTP2 1-300 view protein structure

Promoters
RGD ID:13677638
Promoter ID:EPDNEW_M22968
Type:multiple initiation site
Name:Spry4_1
Description:Mus musculus sprouty RTK signaling antagonist 4 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381838,601,347 - 38,601,407EPDNEW
RGD ID:6829012
Promoter ID:MM_KWN:25094
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:AK035890_9630014M24RIK,   ENSMUST00000097595,   NM_011898,   OTTMUST00000048190
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361838,759,846 - 38,761,727 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1345144 AgrOrtholog
Ensembl Genes ENSMUSG00000024427 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000025295 ENTREZGENE
  ENSMUST00000025295.8 UniProtKB/Swiss-Prot
InterPro Sprouty UniProtKB/Swiss-Prot
  Sprouty_domain UniProtKB/Swiss-Prot
KEGG Report mmu:24066 UniProtKB/Swiss-Prot
MGD MGI:1345144 ENTREZGENE
NCBI Gene 24066 ENTREZGENE
PANTHER PTHR12365:SF6 UniProtKB/Swiss-Prot
  SPROUTY UniProtKB/Swiss-Prot
Pfam Sprouty UniProtKB/Swiss-Prot
PhenoGen Spry4 PhenoGen
PROSITE SPR UniProtKB/Swiss-Prot
UniProt Q543R1 ENTREZGENE
  Q9QXV7 ENTREZGENE
  Q9WTP2 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q543R1 UniProtKB/Swiss-Prot
  Q9QXV7 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-10-31 Spry4  sprouty RTK signaling antagonist 4    sprouty homolog 4 (Drosophila)  Symbol and/or name change 5135510 APPROVED