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Gene: Dlc1 (deleted in liver cancer 1) Mus musculus
Symbol: Dlc1
Name: deleted in liver cancer 1
Description: Predicted to have several functions, including GTPase activator activity; SH2 domain binding activity; and phospholipase binding activity. Involved in several processes, including actin cytoskeleton organization; focal adhesion assembly; and nervous system development. Predicted to colocalize with the actin filament and stress fiber. Is expressed in several structures, including central nervous system; liver; mandible; placenta; and trigeminal nerve. Orthologous to human DLC1 (DLC1 Rho GTPase activating protein); INTERACTS WITH 1,1-dichloroethene; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrobenzenesulfonic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A730069N07Rik; Arhgap7; dlc-1; FLJ21120; HP; hypothetical protein LOC244425; p122-RhoGAP; rho GTPase-activating protein 7; rho-type GTPase-activating protein 7; RIKEN cDNA A730069N07 gene; stAR-related lipid transfer protein 12; STARD12; START domain-containing protein 12; uncharacterized protein LOC244425
Homo sapiens (human) : DLC1 (DLC1 Rho GTPase activating protein)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Dlc1 (DLC1 Rho GTPase activating protein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dlc1 (DLC1 Rho GTPase activating protein)
Pan paniscus (bonobo/pygmy chimpanzee) : DLC1 (DLC1 Rho GTPase activating protein)
Canis lupus familiaris (dog) : DLC1 (DLC1 Rho GTPase activating protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dlc1 (DLC1 Rho GTPase activating protein)
Sus scrofa (pig) : DLC1 (DLC1 Rho GTPase activating protein)
more info ...
Related Pseudogenes: Gm18297  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38836,567,739 - 36,953,184 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37837,630,799 - 37,676,928 (-)NCBIGRCm37mm9NCBIm37
MGSCv36837,630,799 - 37,676,928 (-)NCBImm8
Celera839,196,109 - 39,592,727 (-)NCBICelera
Cytogenetic Map8 A4NCBI
cM Map823.05NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Dlc1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 68617
Created: 2001-07-11
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.