Nf1 (neurofibromin 1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Nf1 (neurofibromin 1) Mus musculus
Analyze
Symbol: Nf1
Name: neurofibromin 1
RGD ID: 10973
MGI Page MGI
Description: Exhibits GTPase activator activity. Involved in several processes, including animal organ development; modulation of chemical synaptic transmission; and nervous system development. Localizes to cytoplasm. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; heart; and integumental system. Used to study juvenile myelomonocytic leukemia and neurofibromatosis. Human ortholog(s) of this gene implicated in autistic disorder; brain cancer (multiple); hematologic cancer (multiple); neurofibromatosis 1; and neurofibromatosis-Noonan syndrome. Orthologous to human NF1 (neurofibromin 1); PARTICIPATES IN forkhead class A signaling pathway; syndecan signaling pathway; mitogen activated protein kinase signaling pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AW494271; Dsk; Dsk9; E030030H24Rik; Mhdads; Mhdadsk9; neurofibromatosis 1; neurofibromatosis-related protein NF-1; neurofibromin; Nf-; Nf-1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391179,223,541 - 79,472,435 (+)NCBIGRCm39mm39
GRCm39 Ensembl1179,230,519 - 79,472,438 (+)Ensembl
GRCm381179,339,590 - 79,581,609 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1179,339,693 - 79,581,612 (+)EnsemblGRCm38mm10GRCm38
MGSCv371179,153,394 - 79,395,111 (+)NCBIGRCm37mm9NCBIm37
MGSCv361179,156,087 - 79,397,804 (+)NCBImm8
Celera1189,016,599 - 89,214,295 (+)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1146.74NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model