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Gene: Efna5 (ephrin A5) Mus musculus
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Symbol: Efna5
Name: ephrin A5
Description: Exhibits chemorepellent activity; ephrin receptor binding activity; and neurotrophin TRKB receptor binding activity. Involved in several processes, including cellular response to follicle-stimulating hormone stimulus; cellular response to forskolin; and generation of neurons. Localizes to several cellular components, including the GABA-ergic synapse; adherens junction; and basement membrane. Used to study anencephaly. Is expressed in several structures, including alimentary system; central nervous system; embryo ectoderm; limb; and sensory organ. Orthologous to human EFNA5 (ephrin A5); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; INTERACTS WITH 1,1-dichloroethene; 3-methylcholanthrene; 4-hydroxyphenyl retinamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AL-1; AV158822; EFL-5; EPH-related receptor tyrosine kinase ligand 7; ephrin-A5; Epl7; LERK-7; RAGS
Orthologs:
Homo sapiens (human) : EFNA5 (ephrin A5)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Efna5 (ephrin A5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Efna5 (ephrin A5)
Pan paniscus (bonobo/pygmy chimpanzee) : EFNA5 (ephrin A5)
Canis lupus familiaris (dog) : EFNA5 (ephrin A5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Efna5 (ephrin A5)
Sus scrofa (pig) : EFNA5 (ephrin A5)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1762,604,184 - 62,881,317 (-)Ensembl
GRCm381762,602,957 - 62,881,317 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371762,952,306 - 63,230,666 (-)NCBIGRCm37mm9NCBIm37
MGSCv361762,290,210 - 62,566,779 (-)NCBImm8
Celera1766,941,186 - 67,218,870 (-)NCBICelera
Cytogenetic Map17 E1.1NCBI
cM Map1732.57NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Efna5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732052
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-12-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.