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Gene: Efna5 (ephrin A5) Mus musculus
Symbol: Efna5
Name: ephrin A5
Description: Exhibits chemorepellent activity; ephrin receptor binding activity; and neurotrophin TRKB receptor binding activity. Involved in several processes, including cellular response to follicle-stimulating hormone stimulus; cellular response to forskolin; and generation of neurons. Localizes to several cellular components, including the GABA-ergic synapse; adherens junction; and basement membrane. Used to study anencephaly. Is expressed in several structures, including alimentary system; central nervous system; embryo ectoderm; limb; and sensory organ. Orthologous to human EFNA5 (ephrin A5); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; INTERACTS WITH 1,1-dichloroethene; 3-methylcholanthrene; 4-hydroxyphenyl retinamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AL-1; AV158822; EFL-5; EPH-related receptor tyrosine kinase ligand 7; ephrin-A5; Epl7; LERK-7; RAGS
Homo sapiens (human) : EFNA5 (ephrin A5)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Efna5 (ephrin A5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Efna5 (ephrin A5)
Pan paniscus (bonobo/pygmy chimpanzee) : EFNA5 (ephrin A5)
Canis lupus familiaris (dog) : EFNA5 (ephrin A5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Efna5 (ephrin A5)
Sus scrofa (pig) : EFNA5 (ephrin A5)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1762,604,184 - 62,881,317 (-)Ensembl
GRCm381762,602,957 - 62,881,317 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371762,952,306 - 63,230,666 (-)NCBIGRCm37mm9NCBIm37
MGSCv361762,290,210 - 62,566,779 (-)NCBImm8
Celera1766,941,186 - 67,218,870 (-)NCBICelera
Cytogenetic Map17 E1.1NCBI
cM Map1732.57NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Efna5
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732052
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-12-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.