Phldb2 (pleckstrin homology like domain, family B, member 2) - Rat Genome Database

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Gene: Phldb2 (pleckstrin homology like domain, family B, member 2) Mus musculus
Analyze
Symbol: Phldb2
Name: pleckstrin homology like domain, family B, member 2
RGD ID: 1558249
MGI Page MGI
Description: Predicted to be involved in several processes, including negative regulation of focal adhesion assembly; regulation of cytoskeleton organization; and regulation of embryonic development. Predicted to colocalize with focal adhesion. Orthologous to human PHLDB2 (pleckstrin homology like domain family B member 2); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AV253284; C820004H04Rik; LL; LL5b; LL5beta; pleckstrin homology-like domain family B member 2; pleckstrin homology-like domain, family B, member 2; protein LL5-beta
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391645,566,593 - 45,773,961 (-)NCBIGRCm39mm39
GRCm39 Ensembl1645,566,606 - 45,773,961 (-)Ensembl
GRCm381645,746,230 - 45,953,598 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1645,746,243 - 45,953,598 (-)EnsemblGRCm38mm10GRCm38
MGSCv371645,746,346 - 45,844,491 (-)NCBIGRCm37mm9NCBIm37
MGSCv361645,665,575 - 45,763,715 (-)NCBImm8
Celera1646,122,635 - 46,220,830 (-)NCBICelera
Cytogenetic Map16B5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (EXP)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-hydroxypropanoic acid  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
4,4'-sulfonyldiphenol  (EXP)
4-hydroxyphenyl retinamide  (EXP)
6-propyl-2-thiouracil  (ISO)
aflatoxin B1  (EXP,ISO)
antirheumatic drug  (ISO)
aristolochic acid  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
butanal  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbamazepine  (ISO)
choline  (EXP)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (EXP,ISO)
cyclosporin A  (ISO)
dexamethasone  (EXP)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP)
disulfiram  (ISO)
diuron  (ISO)
dorsomorphin  (ISO)
Enterolactone  (ISO)
ethyl methanesulfonate  (ISO)
fenamidone  (EXP)
folic acid  (EXP)
geldanamycin  (ISO)
glyphosate  (ISO)
hexadecanoic acid  (ISO)
isobutanol  (ISO)
L-methionine  (EXP)
melphalan  (ISO)
nefazodone  (ISO)
nimesulide  (ISO)
ochratoxin A  (ISO)
paracetamol  (EXP,ISO)
phenobarbital  (EXP)
pirinixic acid  (EXP)
quercetin  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
tetrachloromethane  (EXP,ISO)
thimerosal  (ISO)
titanium dioxide  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
triphenyl phosphate  (ISO)
triptonide  (EXP)
troglitazone  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)

Phenotype Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12477932   PMID:15489334   PMID:15782199   PMID:15851520   PMID:16141072   PMID:16141073   PMID:21677750  
PMID:21873635   PMID:24885555   PMID:25589673   PMID:28671696   PMID:30867511   PMID:32098917   PMID:32325033  


Genomics

Comparative Map Data
Phldb2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391645,566,593 - 45,773,961 (-)NCBIGRCm39mm39
GRCm39 Ensembl1645,566,606 - 45,773,961 (-)Ensembl
GRCm381645,746,230 - 45,953,598 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1645,746,243 - 45,953,598 (-)EnsemblGRCm38mm10GRCm38
MGSCv371645,746,346 - 45,844,491 (-)NCBIGRCm37mm9NCBIm37
MGSCv361645,665,575 - 45,763,715 (-)NCBImm8
Celera1646,122,635 - 46,220,830 (-)NCBICelera
Cytogenetic Map16B5NCBI
PHLDB2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl3111,732,497 - 111,976,517 (+)EnsemblGRCh38hg38GRCh38
GRCh383111,732,496 - 111,976,517 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh373111,451,343 - 111,695,364 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363113,085,500 - 113,177,826 (+)NCBINCBI36hg18NCBI36
Build 343113,085,499 - 113,177,809NCBI
Celera3109,851,286 - 110,094,444 (+)NCBI
Cytogenetic Map3q13.2NCBI
HuRef3108,826,722 - 109,070,708 (+)NCBIHuRef
CHM1_13111,415,675 - 111,659,409 (+)NCBICHM1_1
Phldb2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21154,859,173 - 55,078,212 (+)NCBI
Rnor_6.0 Ensembl1157,265,732 - 57,481,589 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01160,042,879 - 60,051,229 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01160,429,481 - 60,646,262 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41156,484,223 - 56,564,459 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1154,388,307 - 54,601,451 (+)NCBICelera
Cytogenetic Map11q21NCBI
Phldb2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542712,273,062 - 12,388,217 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542712,284,100 - 12,385,755 (+)NCBIChiLan1.0ChiLan1.0
PHLDB2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13115,803,869 - 116,044,586 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3115,745,634 - 116,044,586 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v03108,878,798 - 109,120,501 (+)NCBIMhudiblu_PPA_v0panPan3
PHLDB2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13316,521,087 - 16,615,774 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3316,497,202 - 16,614,132 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3316,500,237 - 16,717,632 (+)NCBI
ROS_Cfam_1.03316,635,502 - 16,853,682 (+)NCBI
UMICH_Zoey_3.13316,446,434 - 16,663,884 (+)NCBI
UNSW_CanFamBas_1.03316,492,184 - 16,707,808 (+)NCBI
UU_Cfam_GSD_1.03317,037,057 - 17,254,141 (+)NCBI
Phldb2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602137,792,508 - 137,991,275 (-)NCBI
SpeTri2.0NW_004936834592,688 - 791,533 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PHLDB2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13147,778,053 - 148,087,744 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113147,778,420 - 148,025,943 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
PHLDB2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12268,821,958 - 69,059,087 (-)NCBI
ChlSab1.1 Ensembl2268,821,742 - 69,059,087 (-)Ensembl
Vero_WHO_p1.0NW_02366604197,417,840 - 97,653,649 (+)NCBI
Phldb2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473136,596,812 - 36,871,963 (-)NCBI

Position Markers
AW742898  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381645,746,480 - 45,746,724UniSTSGRCm38
MGSCv371645,746,593 - 45,746,837UniSTSGRCm37
Celera1646,122,882 - 46,123,126UniSTS
Cytogenetic Map16B5UniSTS
Whitehead/MRC_RH16540.37UniSTS
AV253284  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381645,746,310 - 45,746,446UniSTSGRCm38
MGSCv371645,746,423 - 45,746,559UniSTSGRCm37
Celera1646,122,712 - 46,122,848UniSTS
Cytogenetic Map16B5UniSTS
Whitehead/MRC_RH16547.41UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226768Tibl9_mtibia length 9, 5 week (mouse)16350000051600000Mouse
27226785Feml12_mfemur length 12, 5 week (mouse)16350000064800000Mouse
26884432Zlq7_mzygomatic length QTL 7, 10 week (mouse)16400000064800000Mouse
1357763Lp1_mlymphocyte proliferation 1 (mouse)Not determined16672511565669666Mouse
26884376Skwq4_mskull length QTL 4, 5 week (mouse)16860000091100000Mouse
1301086Lprm5_mlymphoproliferation modifier 5 (mouse)Not determined161203007246030171Mouse
1301841Lrnx9_mlearning-contextual 9 (mouse)Not determined161240654246406653Mouse
10045614Rapop6_mradiation-induced apoptosis 6 (mouse)Not determined161498410348984214Mouse
4142236Pstc4_mperiosteal circumference 4 (mouse)Not determined161570409149704294Mouse
1357517Bwtn1_mbody weight at necropsy 1 (mouse)Not determined162020057985803938Mouse
1300534Bmd15_mbone mineral density 15 (mouse)Not determined162211802156118212Mouse
4141179Ipng3_mimprinted postnatal growth 3 (mouse)Not determined2295650257773713Mouse
1300915Lmr12_mleishmaniasis resistance 12 (mouse)Not determined162897245062972589Mouse
11059559Lmr12a_mleishmaniasis resistance 12a (mouse)162897245062972589Mouse
11059560Lmr12b_mleishmaniasis resistance 12b (mouse)162897245062972589Mouse
11049571Lmr12c_mleishmaniasis resistance 12c (mouse)162897245062972589Mouse
1301070Cypr1_mcytokine production 1 (mouse)Not determined163249243266492570Mouse
4142187Arrd3_mage-related retinal degeneration 3 (mouse)Not determined3270409165669666Mouse
1302096Aod1a_mautoimmune ovarian dysgenesis 1a (mouse)Not determined163562627392776120Mouse
26884416Bzwq5_mbi-zygomatic width QTL 5, 5 week (mouse)163750000084900000Mouse
4142112Skts-fp3_mskin tumor susceptibility in FVB and PWK 3 (mouse)Not determined164023351973127497Mouse
11522747Eae41_mexperimental allergic encephalomyelitis susceptibility 41 (mouse)164057877278218584Mouse
1301138Pcd4ts3_mp-glycoprotein positive CD4 T cell subset 3 (mouse)Not determined164077356074773713Mouse
1357778Diobq_mdiet-induced obesity QTL (mouse)Not determined164237745482534286Mouse
1301719Remslp3_mrapid eye movement sleep 3 (mouse)Not determined164456298778563143Mouse
4141212Imraq3_mimmune response to AAV2 QTL 3 (mouse)Not determined164456298778563143Mouse
10053677Eae46_mexperimental allergic encephalomyelitis susceptibility 46 (mouse)Not determined164539769878952955Mouse
1558836Dice1b_mdetermination of interleukin 4 commitment 1b (mouse)Not determined164569063772477597Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1798
Count of miRNA genes:697
Interacting mature miRNAs:873
Transcripts:ENSMUST00000036355, ENSMUST00000076333, ENSMUST00000125433, ENSMUST00000128365, ENSMUST00000131003, ENSMUST00000133111, ENSMUST00000134802, ENSMUST00000136317, ENSMUST00000136405, ENSMUST00000142697, ENSMUST00000151300
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001252442 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001357078 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_153412 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006521920 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006521921 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006521922 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006521923 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006521924 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006521925 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006521926 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006521927 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006521928 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006521929 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011245859 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030249019 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030249020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036159837 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036159838 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036159839 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036159840 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036159841 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036159842 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036159843 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036159844 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036159845 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC164979 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC166572 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF506821 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK035655 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK049595 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK050493 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK076541 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK087133 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK165251 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK199939 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK202029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK202362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK219819 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB851780 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC050915 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC060683 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY442240 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466521 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000036355   ⟹   ENSMUSP00000046496
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1645,746,243 - 45,844,378 (-)Ensembl
RefSeq Acc Id: ENSMUST00000076333   ⟹   ENSMUSP00000075672
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1645,746,394 - 45,844,234 (-)Ensembl
RefSeq Acc Id: ENSMUST00000125433
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1645,825,974 - 45,844,343 (-)Ensembl
RefSeq Acc Id: ENSMUST00000128365
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1645,901,041 - 45,901,967 (-)Ensembl
RefSeq Acc Id: ENSMUST00000131003   ⟹   ENSMUSP00000119718
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1645,747,160 - 45,801,571 (-)Ensembl
RefSeq Acc Id: ENSMUST00000133111
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1645,772,260 - 45,789,229 (-)Ensembl
RefSeq Acc Id: ENSMUST00000134802   ⟹   ENSMUSP00000123284
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1645,757,142 - 45,953,598 (-)Ensembl
RefSeq Acc Id: ENSMUST00000136317
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1645,901,232 - 45,953,533 (-)Ensembl
RefSeq Acc Id: ENSMUST00000136405   ⟹   ENSMUSP00000121800
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1645,825,805 - 45,953,493 (-)Ensembl
RefSeq Acc Id: ENSMUST00000142697
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1645,780,335 - 45,791,447 (-)Ensembl
RefSeq Acc Id: ENSMUST00000151300
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1645,762,700 - 45,772,283 (-)Ensembl
RefSeq Acc Id: NM_001252442   ⟹   NP_001239371
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391645,566,593 - 45,664,741 (-)NCBI
GRCm381645,746,230 - 45,844,378 (-)NCBI
Celera1646,122,632 - 46,220,830 (-)ENTREZGENE
cM Map16 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001357078   ⟹   NP_001344007
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391645,566,593 - 45,665,114 (-)NCBI
GRCm381645,746,230 - 45,844,751 (-)NCBI
Sequence:
RefSeq Acc Id: NM_153412   ⟹   NP_700461
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391645,566,593 - 45,664,741 (-)NCBI
GRCm381645,746,230 - 45,844,378 (-)NCBI
MGSCv371645,746,346 - 45,844,491 (-)RGD
Celera1646,122,632 - 46,220,830 (-)ENTREZGENE
cM Map16 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006521920   ⟹   XP_006521983
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391645,566,606 - 45,773,805 (-)NCBI
GRCm381645,746,243 - 45,953,442 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006521921   ⟹   XP_006521984
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391645,566,606 - 45,773,810 (-)NCBI
GRCm381645,746,243 - 45,953,447 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006521922   ⟹   XP_006521985
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391645,566,606 - 45,664,763 (-)NCBI
GRCm381645,746,243 - 45,844,394 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006521923   ⟹   XP_006521986
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391645,566,606 - 45,773,805 (-)NCBI
GRCm381645,746,243 - 45,953,442 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006521924   ⟹   XP_006521987
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391645,566,606 - 45,664,762 (-)NCBI
GRCm381645,746,243 - 45,844,393 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006521925   ⟹   XP_006521988
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391645,566,606 - 45,666,375 (-)NCBI
GRCm381645,746,243 - 45,844,831 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006521926   ⟹   XP_006521989
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391645,566,606 - 45,773,961 (-)NCBI
GRCm381645,746,243 - 45,953,598 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006521927   ⟹   XP_006521990
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391645,566,606 - 45,773,805 (-)NCBI
GRCm381645,746,243 - 45,953,442 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006521928   ⟹   XP_006521991
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391645,566,606 - 45,773,805 (-)NCBI
GRCm381645,746,243 - 45,953,442 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006521929   ⟹   XP_006521992
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391645,566,606 - 45,773,805 (-)NCBI
GRCm381645,746,243 - 45,953,442 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011245859   ⟹   XP_011244161
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391645,566,606 - 45,773,805 (-)NCBI
GRCm381645,746,243 - 45,953,442 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030249019   ⟹   XP_030104879
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391645,566,606 - 45,700,107 (-)NCBI
GRCm381645,746,243 - 45,879,744 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030249020   ⟹   XP_030104880
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391645,566,606 - 45,773,805 (-)NCBI
GRCm381645,746,243 - 45,953,442 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036159837   ⟹   XP_036015730
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391645,566,606 - 45,664,762 (-)NCBI
RefSeq Acc Id: XM_036159838   ⟹   XP_036015731
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391645,566,606 - 45,664,757 (-)NCBI
RefSeq Acc Id: XM_036159839   ⟹   XP_036015732
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391645,566,606 - 45,664,758 (-)NCBI
RefSeq Acc Id: XM_036159840   ⟹   XP_036015733
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391645,566,606 - 45,664,757 (-)NCBI
RefSeq Acc Id: XM_036159841   ⟹   XP_036015734
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391645,566,606 - 45,664,757 (-)NCBI
RefSeq Acc Id: XM_036159842   ⟹   XP_036015735
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391645,566,606 - 45,773,805 (-)NCBI
RefSeq Acc Id: XM_036159843   ⟹   XP_036015736
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391645,566,606 - 45,664,757 (-)NCBI
RefSeq Acc Id: XM_036159844   ⟹   XP_036015737
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391645,566,606 - 45,611,876 (-)NCBI
RefSeq Acc Id: XM_036159845   ⟹   XP_036015738
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391645,566,593 - 45,621,798 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001239371 (Get FASTA)   NCBI Sequence Viewer  
  NP_001344007 (Get FASTA)   NCBI Sequence Viewer  
  NP_700461 (Get FASTA)   NCBI Sequence Viewer  
  XP_006521983 (Get FASTA)   NCBI Sequence Viewer  
  XP_006521984 (Get FASTA)   NCBI Sequence Viewer  
  XP_006521985 (Get FASTA)   NCBI Sequence Viewer  
  XP_006521986 (Get FASTA)   NCBI Sequence Viewer  
  XP_006521987 (Get FASTA)   NCBI Sequence Viewer  
  XP_006521988 (Get FASTA)   NCBI Sequence Viewer  
  XP_006521989 (Get FASTA)   NCBI Sequence Viewer  
  XP_006521990 (Get FASTA)   NCBI Sequence Viewer  
  XP_006521991 (Get FASTA)   NCBI Sequence Viewer  
  XP_006521992 (Get FASTA)   NCBI Sequence Viewer  
  XP_011244161 (Get FASTA)   NCBI Sequence Viewer  
  XP_030104879 (Get FASTA)   NCBI Sequence Viewer  
  XP_030104880 (Get FASTA)   NCBI Sequence Viewer  
  XP_036015730 (Get FASTA)   NCBI Sequence Viewer  
  XP_036015731 (Get FASTA)   NCBI Sequence Viewer  
  XP_036015732 (Get FASTA)   NCBI Sequence Viewer  
  XP_036015733 (Get FASTA)   NCBI Sequence Viewer  
  XP_036015734 (Get FASTA)   NCBI Sequence Viewer  
  XP_036015735 (Get FASTA)   NCBI Sequence Viewer  
  XP_036015736 (Get FASTA)   NCBI Sequence Viewer  
  XP_036015737 (Get FASTA)   NCBI Sequence Viewer  
  XP_036015738 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH50915 (Get FASTA)   NCBI Sequence Viewer  
  AAH60683 (Get FASTA)   NCBI Sequence Viewer  
  AAM33635 (Get FASTA)   NCBI Sequence Viewer  
  BAC29141 (Get FASTA)   NCBI Sequence Viewer  
  BAC33833 (Get FASTA)   NCBI Sequence Viewer  
  BAE38105 (Get FASTA)   NCBI Sequence Viewer  
  EDK98080 (Get FASTA)   NCBI Sequence Viewer  
  Q8K1N2 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_700461   ⟸   NM_153412
- Peptide Label: isoform 2
- UniProtKB: Q8K1N2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001239371   ⟸   NM_001252442
- Peptide Label: isoform 1
- UniProtKB: Q8K1N2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006521986   ⟸   XM_006521923
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_006521983   ⟸   XM_006521920
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006521984   ⟸   XM_006521921
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006521990   ⟸   XM_006521927
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_006521992   ⟸   XM_006521929
- Peptide Label: isoform X11
- Sequence:
RefSeq Acc Id: XP_006521991   ⟸   XM_006521928
- Peptide Label: isoform X10
- Sequence:
RefSeq Acc Id: XP_006521989   ⟸   XM_006521926
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_006521988   ⟸   XM_006521925
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_006521985   ⟸   XM_006521922
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006521987   ⟸   XM_006521924
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_011244161   ⟸   XM_011245859
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: NP_001344007   ⟸   NM_001357078
- Peptide Label: isoform 3
RefSeq Acc Id: XP_030104880   ⟸   XM_030249020
- Peptide Label: isoform X15
RefSeq Acc Id: XP_030104879   ⟸   XM_030249019
- Peptide Label: isoform X2
RefSeq Acc Id: ENSMUSP00000119718   ⟸   ENSMUST00000131003
RefSeq Acc Id: ENSMUSP00000075672   ⟸   ENSMUST00000076333
RefSeq Acc Id: ENSMUSP00000046496   ⟸   ENSMUST00000036355
RefSeq Acc Id: ENSMUSP00000123284   ⟸   ENSMUST00000134802
RefSeq Acc Id: ENSMUSP00000121800   ⟸   ENSMUST00000136405
RefSeq Acc Id: XP_036015738   ⟸   XM_036159845
- Peptide Label: isoform X20
RefSeq Acc Id: XP_036015735   ⟸   XM_036159842
- Peptide Label: isoform X17
RefSeq Acc Id: XP_036015730   ⟸   XM_036159837
- Peptide Label: isoform X9
RefSeq Acc Id: XP_036015732   ⟸   XM_036159839
- Peptide Label: isoform X13
RefSeq Acc Id: XP_036015736   ⟸   XM_036159843
- Peptide Label: isoform X18
RefSeq Acc Id: XP_036015733   ⟸   XM_036159840
- Peptide Label: isoform X14
RefSeq Acc Id: XP_036015734   ⟸   XM_036159841
- Peptide Label: isoform X16
RefSeq Acc Id: XP_036015731   ⟸   XM_036159838
- Peptide Label: isoform X12
RefSeq Acc Id: XP_036015737   ⟸   XM_036159844
- Peptide Label: isoform X19
Protein Domains
PH

Promoters
RGD ID:6827341
Promoter ID:MM_KWN:21122
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney,   Lung,   MEF_B4,   MEF_B6
Transcripts:OTTMUST00000060829
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361645,772,001 - 45,773,052 (-)MPROMDB
RGD ID:6827343
Promoter ID:MM_KWN:21123
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney,   Lung,   MEF_B4,   MEF_B6
Transcripts:OTTMUST00000060830
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361645,788,951 - 45,789,657 (-)MPROMDB
RGD ID:6827342
Promoter ID:MM_KWN:21124
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney,   Lung,   MEF_B4,   MEF_B6
Transcripts:OTTMUST00000060831
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361645,791,501 - 45,792,157 (-)MPROMDB
RGD ID:6827339
Promoter ID:MM_KWN:21126
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney,   Lung,   MEF_B4,   MEF_B6
Transcripts:OTTMUST00000060728
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361645,801,751 - 45,802,251 (-)MPROMDB
RGD ID:6827345
Promoter ID:MM_KWN:21127
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:ENSMUST00000076333,   ENSMUST00000077934,   NM_153412,   OTTMUST00000060833,   UC007ZJA.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361645,844,256 - 45,844,862 (-)MPROMDB
RGD ID:8686300
Promoter ID:EPDNEW_M21181
Type:initiation region
Name:Phldb2_1
Description:Mus musculus pleckstrin homology like domain, family B, member2 , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M21183  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381645,844,330 - 45,844,390EPDNEW
RGD ID:8686304
Promoter ID:EPDNEW_M21183
Type:initiation region
Name:Phldb2_2
Description:Mus musculus pleckstrin homology like domain, family B, member2 , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M21181  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381645,953,556 - 45,953,616EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2444981 AgrOrtholog
Ensembl Genes ENSMUSG00000033149 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000046496 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000075672 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000119718 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000121800 UniProtKB/TrEMBL
  ENSMUSP00000123284 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000036355 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000076333 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000131003 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000134802 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000136405 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro PH-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PHLDB1/2/3_PH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:208177 UniProtKB/Swiss-Prot
MGD MGI:2444981 ENTREZGENE
NCBI Gene 208177 ENTREZGENE
Pfam PF00169 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Phldb2 PhenoGen
PROSITE PH_DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SM00233 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt D3Z069_MOUSE UniProtKB/TrEMBL
  D3Z231_MOUSE UniProtKB/TrEMBL
  F6QU68_MOUSE UniProtKB/TrEMBL
  PHLB2_MOUSE UniProtKB/Swiss-Prot
  Q8BZE3_MOUSE UniProtKB/TrEMBL
  Q8K1N2 ENTREZGENE
UniProt Secondary Q3TNI3 UniProtKB/Swiss-Prot
  Q80Y16 UniProtKB/Swiss-Prot
  Q8BKV3 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-29 Phldb2  pleckstrin homology like domain, family B, member 2    pleckstrin homology-like domain, family B, member 2  Symbol and/or name change 5135510 APPROVED