Phldb2 (pleckstrin homology like domain family B member 2) - Rat Genome Database

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Gene: Phldb2 (pleckstrin homology like domain family B member 2) Chinchilla lanigera
Analyze
Symbol: Phldb2
Name: pleckstrin homology like domain family B member 2
RGD ID: 9022324
Description: INVOLVED IN cell migration (ortholog); establishment of cell polarity (ortholog); establishment of protein localization (ortholog); ASSOCIATED WITH atrial fibrillation (ortholog); genetic disease (ortholog); FOUND IN basal cortex (ortholog); cell leading edge (ortholog); cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: pleckstrin homology-like domain family B member 2; pleckstrin homology-like domain, family B, member 2
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542712,273,062 - 12,388,217 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542712,284,100 - 12,385,755 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Phldb2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542712,273,062 - 12,388,217 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542712,284,100 - 12,385,755 (+)NCBIChiLan1.0ChiLan1.0
PHLDB2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383111,732,496 - 111,976,517 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3111,732,497 - 111,976,517 (+)EnsemblGRCh38hg38GRCh38
GRCh373111,451,343 - 111,695,364 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363113,085,500 - 113,177,826 (+)NCBINCBI36Build 36hg18NCBI36
Build 343113,085,499 - 113,177,809NCBI
Celera3109,851,286 - 110,094,444 (+)NCBICelera
Cytogenetic Map3q13.2NCBI
HuRef3108,826,722 - 109,070,708 (+)NCBIHuRef
CHM1_13111,415,675 - 111,659,409 (+)NCBICHM1_1
T2T-CHM13v2.03114,453,343 - 114,697,610 (+)NCBIT2T-CHM13v2.0
Phldb2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391645,566,593 - 45,773,961 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1645,566,606 - 45,773,961 (-)EnsemblGRCm39 Ensembl
GRCm381645,746,230 - 45,953,598 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1645,746,243 - 45,953,598 (-)EnsemblGRCm38mm10GRCm38
MGSCv371645,746,346 - 45,844,491 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361645,665,575 - 45,763,715 (-)NCBIMGSCv36mm8
Celera1646,122,635 - 46,220,830 (-)NCBICelera
Cytogenetic Map16B5NCBI
cM Map1630.08NCBI
Phldb2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81168,321,738 - 68,540,724 (+)NCBIGRCr8
mRatBN7.21154,859,173 - 55,078,212 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1154,859,135 - 55,078,467 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01160,042,879 - 60,051,229 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1157,265,732 - 57,481,589 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01160,429,481 - 60,646,262 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41156,484,223 - 56,564,459 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1154,388,307 - 54,601,451 (+)NCBICelera
Cytogenetic Map11q21NCBI
PHLDB2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22109,844,347 - 109,975,856 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13109,849,118 - 109,980,637 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03108,878,798 - 109,120,501 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13115,803,869 - 116,044,586 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3115,745,634 - 116,044,586 (+)Ensemblpanpan1.1panPan2
PHLDB2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13316,521,087 - 16,615,774 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3316,497,202 - 16,614,132 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3316,500,237 - 16,717,632 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03316,635,502 - 16,853,682 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3316,737,741 - 16,853,566 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13316,446,434 - 16,663,884 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03316,492,184 - 16,707,808 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03317,037,057 - 17,254,141 (+)NCBIUU_Cfam_GSD_1.0
Phldb2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602137,792,508 - 137,991,275 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936834592,584 - 793,386 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936834592,688 - 791,533 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PHLDB2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13147,778,370 - 147,879,794 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113147,778,420 - 148,025,943 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
PHLDB2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12268,821,958 - 69,059,087 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2268,821,742 - 69,059,087 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604197,417,840 - 97,653,649 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Phldb2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473136,593,871 - 36,872,200 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473136,596,812 - 36,871,963 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000018238   ⟹   ENSCLAP00000018060
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495542712,273,062 - 12,388,217 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000018239   ⟹   ENSCLAP00000018061
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495542712,301,147 - 12,385,420 (+)Ensembl
RefSeq Acc Id: XM_005386372   ⟹   XP_005386429
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542712,284,100 - 12,385,755 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013515158   ⟹   XP_013370612
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542712,301,133 - 12,385,755 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013515159   ⟹   XP_013370613
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542712,301,133 - 12,385,755 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013515160   ⟹   XP_013370614
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542712,301,133 - 12,385,755 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013515161   ⟹   XP_013370615
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542712,298,492 - 12,385,755 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013515162   ⟹   XP_013370616
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542712,301,133 - 12,385,755 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_005386429   ⟸   XM_005386372
- Peptide Label: isoform X4
- UniProtKB: A0A8C2VMY5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013370615   ⟸   XM_013515161
- Peptide Label: isoform X4
- UniProtKB: A0A8C2VMY5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013370613   ⟸   XM_013515159
- Peptide Label: isoform X2
- UniProtKB: A0A8C2VTC3 (UniProtKB/TrEMBL),   A0A8C2VMY5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013370616   ⟸   XM_013515162
- Peptide Label: isoform X5
- UniProtKB: A0A8C2VMY5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013370612   ⟸   XM_013515158
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VMY5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013370614   ⟸   XM_013515160
- Peptide Label: isoform X3
- UniProtKB: A0A8C2VMY5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000018060   ⟸   ENSCLAT00000018238
RefSeq Acc Id: ENSCLAP00000018061   ⟸   ENSCLAT00000018239
Protein Domains
PH


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000012390 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000018238 ENTREZGENE
  ENSCLAT00000018238.1 UniProtKB/TrEMBL
  ENSCLAT00000018239 ENTREZGENE
  ENSCLAT00000018239.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
InterPro PH-like_dom_sf UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
  PHLDB1/2/3_PH UniProtKB/TrEMBL
NCBI Gene Phldb2 ENTREZGENE
PANTHER PLECKSTRIN HOMOLOGY-LIKE DOMAIN FAMILY B MEMBER 2 UniProtKB/TrEMBL
  PLECKSTRIN HOMOLOGY-LIKE DOMAIN, FAMILY B, MEMBER 3 UniProtKB/TrEMBL
Pfam PF00169 UniProtKB/TrEMBL
PROSITE PH_DOMAIN UniProtKB/TrEMBL
SMART SM00233 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
UniProt A0A8C2VMY5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2VTC3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Phldb2  pleckstrin homology like domain family B member 2    pleckstrin homology-like domain, family B, member 2  Symbol and/or name change 5135510 APPROVED