Myoc (myocilin) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Myoc (myocilin) Mus musculus
Analyze
Symbol: Myoc
Name: myocilin
RGD ID: 734341
MGI Page MGI
Description: Enables receptor tyrosine kinase binding activity. Involved in several processes, including ERBB2-ERBB3 signaling pathway; neurogenesis; and skeletal muscle hypertrophy. Located in several cellular components, including Golgi apparatus; endoplasmic reticulum; and node of Ranvier. Is expressed in several structures, including brain; eye; genitourinary system; lung; and meninges. Used to study open-angle glaucoma. Human ortholog(s) of this gene implicated in juvenile glaucoma; low tension glaucoma; ocular hypertension; open-angle glaucoma; and primary open angle glaucoma. Orthologous to human MYOC (myocilin); INTERACTS WITH benzo[a]pyrene; bisphenol A; chlordecone.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI957332; GLC; GLC1A; MGC159032; TI; TIGR; trabecular meshwork-induced glucocorticoid response protein
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391162,466,719 - 162,477,263 (+)NCBIGRCm39mm39
GRCm39 Ensembl1162,466,724 - 162,477,262 (+)Ensembl
GRCm381162,639,150 - 162,649,694 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1162,639,155 - 162,649,693 (+)EnsemblGRCm38mm10GRCm38
MGSCv371164,569,281 - 164,579,825 (+)NCBIGRCm37mm9NCBIm37
MGSCv361164,475,844 - 164,486,368 (+)NCBImm8
Celera1165,085,895 - 165,096,434 (+)NCBICelera
Cytogenetic Map1H2.1NCBI
cM Map170.29NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
1. Alward WL, etal., Arch Ophthalmol. 2002 Sep;120(9):1189-97.
2. Alward WL, etal., N Engl J Med. 1998 Apr 9;338(15):1022-7.
3. Anholt RR and Carbone MA, Trends Mol Med. 2013 Oct;19(10):586-93. doi: 10.1016/j.molmed.2013.06.005. Epub 2013 Jul 19.
4. Avisar I, etal., Mol Vis. 2009 Sep 24;15:1945-50.
5. Banerjee D, etal., Mol Vis. 2012;18:1548-57. Epub 2012 Jun 13.
6. Braghini CA, etal., Gene. 2013 Jul 1;523(1):50-7. doi: 10.1016/j.gene.2013.02.054. Epub 2013 Apr 5.
7. Bruttini M, etal., Arch Ophthalmol. 2003 Jul;121(7):1034-8.
8. Campos-Mollo E, etal., Mol Vis. 2007 Sep 13;13:1666-73.
9. Chen J, etal., Mol Vis. 2011;17:1431-5. Epub 2011 May 31.
10. Colomb E, etal., Clin Genet. 2001 Sep;60(3):220-5.
11. Fan BJ, etal., Arch Ophthalmol. 2006 Jan;124(1):102-6.
12. Fan BJ, etal., Mol Vis. 2005 Aug 29;11:625-31.
13. Faucher M, etal., Hum Mol Genet. 2002 Sep 1;11(18):2077-90.
14. Fingert JH, etal., Hum Mol Genet. 1999 May;8(5):899-905.
15. Goldwich A, etal., Kidney Int. 2005 Jan;67(1):140-51.
16. Hewitt AW, etal., Invest Ophthalmol Vis Sci. 2007 Jan;48(1):238-43.
17. Howell KG, etal., J Glaucoma. 2010 Dec;19(9):569-75. doi: 10.1097/IJG.0b013e3181d13020.
18. Jia LY, etal., Invest Ophthalmol Vis Sci. 2009 Aug;50(8):3743-9. doi: 10.1167/iovs.08-3151. Epub 2009 Feb 21.
19. Jia LY, etal., Mol Vis. 2009;15:89-98. Epub 2009 Jan 16.
20. Jurynec MJ, etal., Mol Cell Neurosci. 2003 May;23(1):69-80.
21. Kuchtey J, etal., Eur J Med Genet. 2013 Jun;56(6):292-6. doi: 10.1016/j.ejmg.2013.03.002. Epub 2013 Mar 19.
22. Kumar S, etal., Invest Ophthalmol Vis Sci. 2013 Feb 1;54(2):1280-7. doi: 10.1167/iovs.12-11223.
23. Liu W, etal., Mol Vis. 2012;18:2241-6. Epub 2012 Aug 10.
24. Mendoza-Reinoso V, etal., Mol Vis. 2012;18:2067-75. Epub 2012 Aug 8.
25. Mengkegale M, etal., Mol Vis. 2008 Mar 4;14:413-7.
26. MGD and Homologene mouse data transfer
27. MGD data from the GO Consortium
28. MGD IEA
29. Michels-Rautenstrauss K, etal., Hum Mutat. 2002 Dec;20(6):479-80.
30. Mukhopadhyay A, etal., Mol Vis. 2002 Nov 15;8:442-8.
31. Naskar R and Thanos S, Mol Vis. 2006 Oct 18;12:1199-210.
32. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
33. OMIM Disease Annotation Pipeline
34. Petersen MB, etal., Invest Ophthalmol Vis Sci. 2006 Feb;47(2):620-5.
35. Qu X, etal., Mol Biol Rep. 2010 Jan;37(1):255-61. doi: 10.1007/s11033-009-9667-3. Epub 2009 Aug 18.
36. RGD automated import pipeline
37. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
38. RGD automated import pipeline for gene-chemical interactions
39. Saura M, etal., Eur J Hum Genet. 2005 Mar;13(3):384-7.
40. Souzeau E, etal., Ophthalmology. 2013 Jun;120(6):1135-43. doi: 10.1016/j.ophtha.2012.11.029. Epub 2013 Feb 28.
41. Stone EM, etal., Science. 1997 Jan 31;275(5300):668-70.
42. Torrado M, etal., Hum Mol Genet 2002 May 15;11(11):1291-301.
43. Waryah AM, etal., Gene. 2013 Oct 10;528(2):356-9. doi: 10.1016/j.gene.2013.07.016. Epub 2013 Jul 23.
44. Wiggs JL, etal., Am J Hum Genet. 1998 Nov;63(5):1549-52.
45. Wirtz MK, etal., Invest Ophthalmol Vis Sci. 2010 Jun;51(6):3055-60. doi: 10.1167/iovs.09-4652. Epub 2010 Jan 27.
46. Yen YC, etal., Mol Vis. 2007 Sep 10;13:1627-34.
47. Zhao X, etal., Mol Vis. 2010 Aug 25;16:1728-35.
48. Zillig M, etal., Invest Ophthalmol Vis Sci. 2005 Jan;46(1):223-34.
49. Zode GS, etal., Invest Ophthalmol Vis Sci. 2012 Mar 21;53(3):1557-65. doi: 10.1167/iovs.11-8837. Print 2012 Mar.
Additional References at PubMed
PMID:8889548   PMID:9280311   PMID:9548973   PMID:9588210   PMID:9675094   PMID:9680392   PMID:10320784   PMID:10349636   PMID:10892845   PMID:11042159   PMID:11076861   PMID:11217851  
PMID:11604506   PMID:11726618   PMID:12477932   PMID:12615070   PMID:14749932   PMID:15456875   PMID:15597075   PMID:16141072   PMID:16141073   PMID:16384964   PMID:16392033   PMID:16954374  
PMID:17108164   PMID:17317787   PMID:18436825   PMID:19188438   PMID:20045724   PMID:20382707   PMID:20568247   PMID:21051732   PMID:22371502   PMID:22736606   PMID:23629661   PMID:23897819  
PMID:24563482   PMID:24741044   PMID:24837143   PMID:24952961   PMID:25740847   PMID:27820874   PMID:28167045   PMID:29049729   PMID:30389787   PMID:30395621   PMID:30802039   PMID:31220272  
PMID:32132110  


Genomics

Comparative Map Data
Myoc
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391162,466,719 - 162,477,263 (+)NCBIGRCm39mm39
GRCm39 Ensembl1162,466,724 - 162,477,262 (+)Ensembl
GRCm381162,639,150 - 162,649,694 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1162,639,155 - 162,649,693 (+)EnsemblGRCm38mm10GRCm38
MGSCv371164,569,281 - 164,579,825 (+)NCBIGRCm37mm9NCBIm37
MGSCv361164,475,844 - 164,486,368 (+)NCBImm8
Celera1165,085,895 - 165,096,434 (+)NCBICelera
Cytogenetic Map1H2.1NCBI
cM Map170.29NCBI
MYOC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1171,635,417 - 171,652,688 (-)EnsemblGRCh38hg38GRCh38
GRCh381171,635,417 - 171,652,688 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371171,604,557 - 171,621,828 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361169,871,180 - 169,888,396 (-)NCBINCBI36hg18NCBI36
Build 341168,336,215 - 168,353,430NCBI
Celera1144,713,951 - 144,731,166 (-)NCBI
Cytogenetic Map1q24.3NCBI
HuRef1142,827,834 - 142,845,046 (-)NCBIHuRef
CHM1_11173,026,640 - 173,043,840 (-)NCBICHM1_1
Myoc
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21374,976,730 - 74,987,128 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1374,976,730 - 74,987,127 (+)Ensembl
Rnor_6.01380,517,531 - 80,527,928 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1380,517,536 - 80,527,928 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01385,409,611 - 85,420,008 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41378,303,830 - 78,314,228 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11378,318,017 - 78,328,415 (+)NCBI
Celera1374,726,592 - 74,736,986 (+)NCBICelera
Cytogenetic Map13q22NCBI
Myoc
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540612,182,046 - 12,199,669 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540612,182,115 - 12,194,683 (-)NCBIChiLan1.0ChiLan1.0
MYOC
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11150,841,630 - 150,858,628 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1150,841,630 - 150,858,628 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01147,128,541 - 147,146,227 (-)NCBIMhudiblu_PPA_v0panPan3
MYOC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1727,335,314 - 27,346,821 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl727,335,314 - 27,346,820 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha726,857,046 - 26,868,545 (+)NCBI
ROS_Cfam_1.0727,136,587 - 27,148,065 (+)NCBI
UMICH_Zoey_3.1726,988,106 - 26,999,596 (+)NCBI
UNSW_CanFamBas_1.0727,022,462 - 27,033,986 (+)NCBI
UU_Cfam_GSD_1.0727,264,790 - 27,276,291 (+)NCBI
Myoc
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934497,697,971 - 97,710,064 (+)NCBI
SpeTri2.0NW_00493648115,544,733 - 15,556,813 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MYOC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9114,087,374 - 114,098,743 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19114,087,370 - 114,098,765 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29125,551,261 - 125,562,662 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MYOC
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12557,458,615 - 57,475,329 (+)NCBI
ChlSab1.1 Ensembl2557,459,374 - 57,475,322 (+)Ensembl
Vero_WHO_p1.0NW_02366605559,088,230 - 59,104,345 (+)NCBI
Myoc
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462477110,066,170 - 10,080,257 (+)NCBI

Position Markers
AI957332  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381162,649,412 - 162,649,516UniSTSGRCm38
MGSCv371164,579,543 - 164,579,647UniSTSGRCm37
Celera1165,096,153 - 165,096,257UniSTS
Cytogenetic Map1H2.1UniSTS
Whitehead/MRC_RH12070.9UniSTS
AF039869  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381162,649,286 - 162,649,432UniSTSGRCm38
MGSCv371164,579,417 - 164,579,563UniSTSGRCm37
Celera1165,096,031 - 165,096,173UniSTS
Cytogenetic Map1H2.1UniSTS
Whitehead/MRC_RH12069.59UniSTS
Myoc  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381162,636,275 - 162,636,593UniSTSGRCm38
MGSCv371164,566,406 - 164,566,724UniSTSGRCm37
Celera1165,083,008 - 165,083,326UniSTS
Cytogenetic Map1H2.1UniSTS
cM Map183.6UniSTS
PMC48141P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381162,639,178 - 162,639,665UniSTSGRCm38
MGSCv371164,569,309 - 164,569,796UniSTSGRCm37
Celera1165,085,923 - 165,086,410UniSTS
Cytogenetic Map1H2.1UniSTS
PMC48141P2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381162,639,606 - 162,640,036UniSTSGRCm38
MGSCv371164,569,737 - 164,570,167UniSTSGRCm37
Celera1165,086,351 - 165,086,781UniSTS
Cytogenetic Map1H2.1UniSTS
PMC48141P4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381162,648,230 - 162,649,016UniSTSGRCm38
MGSCv371164,578,361 - 164,579,147UniSTSGRCm37
Celera1165,094,975 - 165,095,761UniSTS
Cytogenetic Map1H2.1UniSTS
PMC48141P3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381162,647,152 - 162,647,595UniSTSGRCm38
MGSCv371164,577,283 - 164,577,726UniSTSGRCm37
Celera1165,093,896 - 165,094,339UniSTS
Cytogenetic Map1H2.1UniSTS
PMC48141P5  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381162,648,817 - 162,649,016UniSTSGRCm38
MGSCv371164,578,948 - 164,579,147UniSTSGRCm37
Celera1165,095,562 - 165,095,761UniSTS
Cytogenetic Map1H2.1UniSTS
PMC48141P7  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381162,638,097 - 162,638,817UniSTSGRCm38
MGSCv371164,568,228 - 164,568,948UniSTSGRCm37
Cytogenetic Map1H2.1UniSTS
PMC48141P6  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381162,648,817 - 162,649,247UniSTSGRCm38
MGSCv371164,578,948 - 164,579,378UniSTSGRCm37
Celera1165,095,562 - 165,095,992UniSTS
Cytogenetic Map1H2.1UniSTS
PMC48141P8  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381162,638,640 - 162,638,817UniSTSGRCm38
MGSCv371164,568,771 - 164,568,948UniSTSGRCm37
Cytogenetic Map1H2.1UniSTS
PMC48141P9  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381162,638,640 - 162,639,201UniSTSGRCm38
MGSCv371164,568,771 - 164,569,332UniSTSGRCm37
Celera1165,085,373 - 165,085,946UniSTS
Cytogenetic Map1H2.1UniSTS
PMC99941P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381162,639,204 - 162,639,376UniSTSGRCm38
MGSCv371164,569,335 - 164,569,507UniSTSGRCm37
Celera1165,085,949 - 165,086,121UniSTS
Cytogenetic Map1H2.1UniSTS
Myoc  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381162,639,204 - 162,639,826UniSTSGRCm38
MGSCv371164,569,335 - 164,569,957UniSTSGRCm37
Celera1165,085,949 - 165,086,571UniSTS
Cytogenetic Map1H2.1UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301710Bmd5_mbone mineral density 5 (mouse)Not determined1139774467173774646Mouse
1301722Cia9_mcollagen induced arthritis QTL 9 (mouse)Not determined145744740189571420Mouse
1301458Skts8_mskin tumor susceptibility 8 (mouse)Not determined1135919071169919261Mouse
1301467Pcir1_mperiosteal circumference 1 (mouse)Not determined1141405603175405702Mouse
1300934Cfbw1_mcystic fibrosis body weight 1 (mouse)Not determined1145317638179317756Mouse
1300948Fglu2_mfasting glucose 2 (mouse)Not determined1157628733191628870Mouse
1301818Ap1q_malcohol preference 1 QTL (mouse)Not determined1147032461167758653Mouse
1301866Cplaq3_mcircadian period of locomotor activity 3 (mouse)Not determined1155893961189895041Mouse
1301189Lmr8_mleishmaniasis resistance 8 (mouse)Not determined1156774467189571420Mouse
1301191Stia1_mserum transfer induced arthritis 1 (mouse)Not determined1141405603175405702Mouse
1301523Ccrs1_mcorpus callosum hemisphere surface size 1 (mouse)Not determined1139774467173774646Mouse
1301565Mnotch_mmodifier of Notch (mouse)Not determined1157628733191628870Mouse
1301596Elnt_mescape latencies during navigation task (mouse)Not determined1162317638194429220Mouse
1301602Bslm4_mbasal locomotor activity 4 (mouse)Not determined1157628733191628870Mouse
1558720Bpq8_mblood pressure QTL 8 (mouse)Not determined1143457095177457233Mouse
1301608Emo3_memotionality 3 (mouse)Not determined1129255120163255255Mouse
1301614Cgnz1_mchronic glomerulonephritis in NZM 1 (mouse)Not determined1152211172186211344Mouse
1302193Cpfd1_mcerebellum pattern fissures (mouse)Not determined1139774467173774646Mouse
1302098Eila1_methanol induced locomotor activity 1 (mouse)Not determined1112081092175641372Mouse
1301431Pcho1_mplasma cholesterol 1 (mouse)Not determined1159435007193435127Mouse
1300777Chol10_mcholesterol 10 (mouse)Not determined9148047933182048047Mouse
1300837Vmbic1_mventral midbrain iron content 1 (mouse)Not determined1139624618173624738Mouse
1300842Sle9_msystematic lupus erythematosus susceptibility 9 (mouse)Not determined1158641251192641372Mouse
1357434Obsty1_mobesity 1 (mouse)Not determined1136334204170334348Mouse
1301894Skull2_mskull morphology 2 (mouse)Not determined1139774467173774646Mouse
1301932Ssta2_msusceptibility to Salmonella typhimurium antigens 2 (mouse)Not determined1155888654189888802Mouse
1357602Vtbt2_mvertebral trabecular bone trait 2 (mouse)Not determined1139774467173774646Mouse
1357618Splq5_mspleen weight QTL 5 (mouse)Not determined1150317922188627115Mouse
4141233Femwf12_mfemur work to failure 12 (mouse)Not determined141405603175405702Mouse
1302128Ity3_mimmunity to S. typhimurium 3 (mouse)Not determined11131228571165311895Mouse
1302132Pbw1_mpentobarbital withdrawal QTL 1 (mouse)Not determined1156004198190004325Mouse
1300571Opfa_mopen field activity (mouse)Not determined1144703778178704023Mouse
1300696Bpq2_mblood pressure QTL 2 (mouse)Not determined1139774467173774646Mouse
1300732Melm2_mmelanoma modifier 2 (mouse)Not determined1157628733191628870Mouse
1300740Tne1_mtotal number errors (mouse)Not determined1139774467173774646Mouse
1300745Gvhd1_mgraft-versus-host disease 1 (mouse)Not determined1157628733191628870Mouse
1357493Lgaq3_mlate growth adjusted QTL 3 (mouse)Not determined1150317922188627115Mouse
1301025Lbw7_mlupus NZB x NZW 7 (mouse)Not determined1152211172186211344Mouse
1301385Radpf2_mradiation pulmonary fibrosis 2 (mouse)Not determined1147249520183092234Mouse
1301408Lore8_mloss of righting induced by ethanol 8 (mouse)Not determined1136002150170002264Mouse
1357889Lprq3_mlipoprotein QTL 3 (mouse)Not determined1152211172186211344Mouse
4141244Bmd5c_mbone mineral density 5c (mouse)Not determined155699229189699330Mouse
4141245Cq2_mcholesterol QTL 2 (mouse)Not determined1157628733191628870Mouse
4141346Skmw12_mskeletal muscle weight 12 (mouse)Not determined150929168184929353Mouse
1301202Yaa4_mY-linked autoimmune acceleration 4 (mouse)Not determined1158641251192641372Mouse
1301216Cbm1_mcerebellum weight 1 (mouse)Not determined1157628733191628870Mouse
1301232Hcs7_mhepatocarcinogenesis susceptibility 7 (mouse)Not determined1156774467168358833Mouse
1301122Cd8mts1_mCD8 T memory cell subset 1 (mouse)Not determined1156004198190004325Mouse
1301134Bmd1_mbone mineral density 1 (mouse)Not determined1156774467189571420Mouse
1301149Lrnx12_mlearning-contextual 12 (mouse)Not determined1112081092168358833Mouse
1301151Hdlq14_mHDL QTL 14 (mouse)Not determined1142661973176662164Mouse
1301164Tir3c_mtrypansomiasis infection response 3c (mouse)Not determined1154804480188804689Mouse
1357567Nidd3k_mNidd3 on KK-A<y> (mouse)Not determined7147249520169211344Mouse
4141149Hbnr4_mHeligmosomoides bakeri nematode resistance 4 (mouse)Not determined147249520189251027Mouse
4141160Cq1_mcholesterol QTL 1 (mouse)Not determined1139624618173624738Mouse
4141165Bglu3_mblood glucose level 3 (mouse)Not determined156004198190004325Mouse
1301301Sle1_msystemic lupus erythmatosus susceptibility 1 (mouse)Not determined1152211172186211344Mouse
1300823Ath9_matherosclerosis 9 (mouse)Not determined1160285202194285317Mouse
1300969Sluc5_msusceptibility to lung cancer 5 (mouse)Not determined1151358674185358833Mouse
1301619Cafq1_mcaffeine metabolism QTL 1 (mouse)Not determined1155888654189888802Mouse
1301632Bw8q1_mbody weight at 8 weeks QTL 1 (mouse)Not determined1161373696195373830Mouse
1357485Lgq4_mlate growth QTL 4 (mouse)Not determined1150317922188627115Mouse
4142119Bpq21_mblood pressure QTL 21 (mouse)Not determined1152211172186211344Mouse
4142149Ctex_mCtla4 expression QTL (mouse)Not determined1153681660175641372Mouse
4142159Nba2_mNew Zealand Black autoimmunity 2 (mouse)Not determined152007542186007711Mouse
4142182Shali5_msurvival time to hyperoxic acute lung injury 5 (mouse)Not determined155706491186261999Mouse
4141554Cfmq1_mcystic fibrosis modifier QTL 1 (mouse)Not determined1152211172186211344Mouse
4142291Aec2_mautoimmune exocrinopathy 2 (mouse)Not determined52418578182423027Mouse
10043899Hdlq99_mHDL QTL 99 (mouse)Not determined1148047933182048047Mouse
10043963Obq25_mobesity QTL 25 (mouse)Not determined1154582944188582944Mouse
10402498Lmr20_mleishmaniasis resistance 20 (mouse)Not determined1158641251192641372Mouse
10412074Nhdlt1_mnon-HDL cholesterol and triglyceride levels 1 (mouse)Not determined1153848421187848536Mouse
10054490Opefa_mopen field activity (mouse)Not determined1153885284187885284Mouse
10054270Nba10_mNew Zealand Black autoimmunity 10 (mouse)Not determined1152919071186706423Mouse
10054271Nba9_mNew Zealand Black autoimmunity 9 (mouse)Not determined1155698056189699966Mouse
10412162Nobq3_mNew Zealand obese QTL 3 (mouse)Not determined1104005680191493284Mouse
10412185Hcs9_mhepatocarcinogenesis susceptibility 9 (mouse)Not determined163815531189571420Mouse
4142014Wbcq5_mwhite blood cell quantitative locus 5 (mouse)Not determined1141267440175267586Mouse
27095935Ulnl5_mulna length 5, 10 week (mouse)1128800000181500000Mouse
27095915Scvln13_msacral vertebrae length 2, 16 week (mouse)1117600000180000000Mouse
11059558Lmr20c_mleishmaniasis resistance 20c (mouse)1158641251192641372Mouse
11059557Lmr20a_mleishmaniasis resistance 20a (mouse)1158641251192641372Mouse
12791001Aath6_maortic arch atherosclerosis 6 (mouse)1147391821181391821Mouse
27226799Feml5_mfemur length 5, 5 week (mouse)1122100000165000000Mouse
11081167Tir8_mtrypanosome infection response 8 (mouse)1155888654189888802Mouse
12790996Aath2_maortic arch atherosclerosis 2 (mouse)1145250061179250061Mouse
12910522Scgq2_mspontaneous crescentic glomerulonephritis QTL 2 (mouse)1147249520171804689Mouse
12790987Tgl5_mtriglyceride 5 (mouse)1160269591194269591Mouse
13452397Leusq4_mleucocytosis susceptibility QTL 4 (mouse)1156774467170976071Mouse
14746980Manh50_mmandible shape 50 (mouse)1134255813168255813Mouse
12790988Phdlc5_mplasma HDL cholesterol 5 (mouse)9160269591194269591Mouse
11251722Ewc1_methanol withdrawal and consumption 1 (mouse)1152305175186305175Mouse
27226767Tibl10_mtibia length 10, 10 week (mouse)1121800000165000000Mouse
13464138Hdlq107_mHDL QTL 107 (mouse)1152305175186305175Mouse
11049576Lmr8a_mleishmaniasis resistance 8a (mouse)1139774467173774646Mouse
12790984Pcho7_mplasma cholesterol 7 (mouse)1147391821181391821Mouse
12910521Scgq1_mspontaneous crescentic glomerulonephritis QTL 1 (mouse)1156774467176435127Mouse
11533913Rd6m1_mretinal degeneration 6 modifier 1 (mouse)1141405603175405702Mouse
12904957Gmmq1_mgastrocnemius muscle mass QTL 1 (mouse)1155175373189175373Mouse
13824984Twq5_mtestis weight QTL 5 (mouse)13000000185000000Mouse
11537365Cnes4_mC. neoformans susceptibility locus 4 (mouse)1144621573178621573Mouse
13452394Leusq1_mleucocytosis susceptibility QTL 1 (mouse)1156774467168358833Mouse
12904936Edlmmq1_mextensor digitorum longus muscle mass QTL 1 (mouse)1155175373189175373Mouse
27095901Scvln8_msacral vertebrae length 2, 10 week (mouse)194200000172200000Mouse
26884448Sklq1_mskull length QTL 1, 5 week (mouse)176000000181500000Mouse
12904944Tammq1_mtibialis anterior muscle mass QTL 1 (mouse)1155175373189175373Mouse
11059556Lmr20b_mleishmaniasis resistance 20b (mouse)1158641251192641372Mouse
10766456Sle21_msystematic lupus erythematosus susceptibility 21 (mouse)1156004198190004325Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:462
Count of miRNA genes:312
Interacting mature miRNAs:355
Transcripts:ENSMUST00000028020
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000028020   ⟹   ENSMUSP00000028020
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1162,466,724 - 162,477,262 (+)Ensembl
GRCm38.p6 Ensembl1162,639,155 - 162,649,693 (+)Ensembl
RefSeq Acc Id: NM_010865   ⟹   NP_034995
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391162,466,719 - 162,477,263 (+)NCBI
GRCm381162,639,150 - 162,649,694 (+)ENTREZGENE
MGSCv371164,569,281 - 164,579,825 (+)RGD
Celera1165,085,895 - 165,096,434 (+)RGD
cM Map1 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_034995   ⟸   NM_010865
- Peptide Label: precursor
- UniProtKB: O70624 (UniProtKB/Swiss-Prot),   Q05AC1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000028020   ⟸   ENSMUST00000028020
Protein Domains
Olfactomedin-like

Promoters
RGD ID:6875468
Promoter ID:EPDNEW_M1185
Type:single initiation site
Name:Myoc_1
Description:Mus musculus myocilin , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381162,639,155 - 162,639,215EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1202864 AgrOrtholog
Ensembl Genes ENSMUSG00000026697 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000028020 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000028020 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro Myocilin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Olfac-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:17926 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1202864 ENTREZGENE
NCBI Gene 17926 ENTREZGENE
PANTHER PTHR23192:SF33 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam OLF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Myoc PhenoGen
PROSITE OLF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART OLF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt MYOC_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q05AC1 ENTREZGENE, UniProtKB/TrEMBL
  Q3UN79_MOUSE UniProtKB/TrEMBL
UniProt Secondary O70289 UniProtKB/Swiss-Prot