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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:increased ovary tumor incidence
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Accession:MP:0008000 term browser browse the term
Definition:greater than the expected number of neoplams in the ovary occurring in a specific population in a given time period
Synonyms:exact_synonym: increased ovarian tumor incidence;   increased ovarian tumour incidence;   increased ovary tumour incidence
 related_synonym: ovarian tumor;   ovarian tumour


show annotations for term's descendants           Sort by:
increased ovary tumor incidence term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amhr2 anti-Mullerian hormone type 2 receptor IAGP MGI PMID:17967875 PMID:18687666 PMID:27354067 NCBI chr15:102,353,437...102,363,075
Ensembl chr15:102,353,802...102,363,068 		JBrowse link
G Apc APC, WNT signaling pathway regulator IAGP MGI PMID:24474556 NCBI chr18:34,353,350...34,455,243
Ensembl chr18:34,353,977...34,455,605 		JBrowse link
G Arid1a AT-rich interaction domain 1A IAGP MGI PMID:25625625 NCBI chr 4:133,406,319...133,484,682
Ensembl chr 4:133,406,319...133,484,080 		JBrowse link
G Atm ataxia telangiectasia mutated IAGP MGI PMID:12195425 NCBI chr 9:53,348,422...53,448,125
Ensembl chr 9:53,350,449...53,448,040 		JBrowse link
G Bap1 Brca1 associated protein 1 IAGP MGI PMID:26896281 NCBI chr14:30,973,358...30,981,887
Ensembl chr14:30,973,407...30,981,901 		JBrowse link
G Brca1 breast cancer 1, early onset IAGP MGI PMID:22617326 NCBI chr11:101,379,587...101,442,808
Ensembl chr11:101,379,590...101,442,781 		JBrowse link
G Brca2 breast cancer 2, early onset IAGP MGI PMID:22617326 NCBI chr 5:150,445,759...150,493,612
Ensembl chr 5:150,446,095...150,493,794 		JBrowse link
G Cdkn1b cyclin dependent kinase inhibitor 1B IAGP MGI PMID:27354067 NCBI chr 6:134,897,364...134,902,488
Ensembl chr 6:134,897,364...134,902,476 		JBrowse link
G Ctnnb1 catenin beta 1 IAGP MGI PMID:18687666 PMID:21860425 NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573 		JBrowse link
G Cul9 cullin 9 IAGP MGI PMID:21487039 NCBI chr17:46,811,535...46,857,314
Ensembl chr17:46,811,498...46,857,314 		JBrowse link
G Dmtf1 cyclin D binding myb like transcription factor 1 IAGP MGI PMID:17936562 NCBI chr 5:9,168,868...9,211,782
Ensembl chr 5:9,168,801...9,211,776 		JBrowse link
G Esr1 estrogen receptor 1 (alpha) IAGP MGI PMID:12855748 NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614 		JBrowse link
G Esr2 estrogen receptor 2 (beta) IAGP MGI PMID:12855748 NCBI chr12:76,167,193...76,224,033
Ensembl chr12:76,167,193...76,224,033 		JBrowse link
G Fancf Fanconi anemia, complementation group F IAGP MGI PMID:21915857 NCBI chr 7:51,510,325...51,512,015
Ensembl chr 7:51,510,325...51,512,015 		JBrowse link
G Foxo3 forkhead box O3 IAGP MGI PMID:17254969 NCBI chr10:42,057,841...42,152,691
Ensembl chr10:42,057,837...42,152,751 		JBrowse link
G Foxo4 forkhead box O4 IAGP MGI PMID:17254969 NCBI chr  X:100,297,855...100,304,479
Ensembl chr  X:100,298,134...100,304,479 		JBrowse link
G Fshr follicle stimulating hormone receptor IAGP MGI PMID:12135868 NCBI chr17:89,292,380...89,508,103
Ensembl chr17:89,292,380...89,508,103 		JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:25625625 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,054,294 		JBrowse link
G Helq helicase, POLQ-like IAGP MGI PMID:24005329 NCBI chr 5:100,910,010...100,946,529
Ensembl chr 5:100,910,011...100,946,464 		JBrowse link
G Htatip2 HIV-1 Tat interactive protein 2 IAGP MGI PMID:14695192 NCBI chr 7:49,408,761...49,423,748
Ensembl chr 7:49,408,863...49,423,723 		JBrowse link
G Inha inhibin alpha IAGP MGI PMID:1448148 PMID:12855748 PMID:17652186 NCBI chr 1:75,483,872...75,487,010
Ensembl chr 1:75,483,721...75,487,010 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase IAGP MGI PMID:27354067 NCBI chr 5:75,735,647...75,817,382
Ensembl chr 5:75,735,576...75,817,382 		JBrowse link
G Kras Kirsten rat sarcoma viral oncogene homolog IAGP MGI PMID:17936562 PMID:20505730 PMID:21860425 NCBI chr 6:145,162,425...145,197,631
Ensembl chr 6:145,162,425...145,195,965 		JBrowse link
G Lats1 large tumor suppressor IAGP MGI PMID:9988269 NCBI chr10:7,556,964...7,592,225
Ensembl chr10:7,556,978...7,592,224 		JBrowse link
G Mcm8 minichromosome maintenance 8 homologous recombination repair factor IAGP MGI PMID:22771120 NCBI chr 2:132,658,061...132,686,117
Ensembl chr 2:132,658,061...132,686,117 		JBrowse link
G Mcm9 minichromosome maintenance 9 homologous recombination repair factor IAGP MGI PMID:21987787 NCBI chr10:53,412,411...53,507,251
Ensembl chr10:53,412,411...53,506,535 		JBrowse link
G Men1 multiple endocrine neoplasia 1 IAGP MGI PMID:12819299 PMID:17044021 PMID:19620250 NCBI chr19:6,385,009...6,390,924
Ensembl chr19:6,385,009...6,390,921 		JBrowse link
G Msh2 mutS homolog 2 IAGP MGI PMID:15126346 NCBI chr17:87,979,960...88,031,141
Ensembl chr17:87,979,758...88,031,141 		JBrowse link
G Mutyh mutY DNA glycosylase IAGP MGI PMID:15126346 NCBI chr 4:116,664,846...116,676,641
Ensembl chr 4:116,664,920...116,676,637 		JBrowse link
G Ogg1 8-oxoguanine DNA-glycosylase 1 IAGP MGI PMID:15126346 NCBI chr 6:113,303,959...113,311,149
Ensembl chr 6:113,303,933...113,312,029 		JBrowse link
G Pcsk6 proprotein convertase subtilisin/kexin type 6 IAGP MGI PMID:21183657 NCBI chr 7:65,511,884...65,700,134
Ensembl chr 7:65,511,482...65,700,134 		JBrowse link
G Pgr progesterone receptor IAGP MGI PMID:24474556 NCBI chr 9:8,890,017...8,968,612
Ensembl chr 9:8,899,834...8,968,612 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha IAGP MGI PMID:22214849 NCBI chr 3:32,451,203...32,520,256
Ensembl chr 3:32,451,820...32,522,635 		JBrowse link
G Pinx1 PIN2/TERF1 interacting, telomerase inhibitor 1 IAGP MGI PMID:21436583 NCBI chr14:64,097,728...64,157,311
Ensembl chr14:64,097,813...64,157,308 		JBrowse link
G Pten phosphatase and tensin homolog IAGP MGI PMID:18687666 PMID:20505730 PMID:21860425 PMID:22214849 NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560 		JBrowse link
G Rb1 RB transcriptional corepressor 1 IAGP MGI PMID:12839925 NCBI chr14:73,430,298...73,563,446
Ensembl chr14:73,421,113...73,563,262 		JBrowse link
G Rint1 RAD50 interactor 1 IAGP MGI PMID:17470549 NCBI chr 5:23,992,700...24,028,582
Ensembl chr 5:23,992,709...24,025,367 		JBrowse link
G Sav1 salvador family WW domain containing 1 IAGP MGI PMID:20404163 NCBI chr12:70,011,786...70,033,864
Ensembl chr12:70,011,786...70,033,776 		JBrowse link
G Smad1 SMAD family member 1 IAGP MGI PMID:17967875 NCBI chr 8:80,065,024...80,126,057
Ensembl chr 8:80,065,024...80,126,147 		JBrowse link
G Smad3 SMAD family member 3 IAGP MGI PMID:17652186 NCBI chr 9:63,554,048...63,665,276
Ensembl chr 9:63,554,049...63,665,276 		JBrowse link
G Smad4 SMAD family member 4 IAGP MGI PMID:16518688 NCBI chr18:73,767,861...73,836,862
Ensembl chr18:73,772,080...73,836,851 		JBrowse link
G Smad5 SMAD family member 5 IAGP MGI PMID:17967875 NCBI chr13:56,850,804...56,890,191
Ensembl chr13:56,850,823...56,890,190 		JBrowse link
G Smad9 SMAD family member 9 IAGP MGI PMID:17967875 NCBI chr 3:54,662,873...54,709,162
Ensembl chr 3:54,663,003...54,708,678 		JBrowse link
G Sptbn1 spectrin beta, non-erythrocytic 1 IAGP MGI PMID:20739274 NCBI chr11:30,049,395...30,218,384
Ensembl chr11:30,049,395...30,218,175 		JBrowse link
G Stk11 serine/threonine kinase 11 IAGP MGI PMID:16278673 NCBI chr10:79,951,602...79,966,513
Ensembl chr10:79,951,637...79,966,516 		JBrowse link
G Tom1l2 target of myb1-like 2 (chicken) IAGP MGI PMID:18343975 NCBI chr11:60,114,622...60,243,766
Ensembl chr11:60,117,540...60,243,731 		JBrowse link
G Trim37 tripartite motif-containing 37 IAGP MGI PMID:27044324 NCBI chr11:87,017,675...87,141,700
Ensembl chr11:87,017,903...87,111,509 		JBrowse link
G Trp53 transformation related protein 53 IAGP MGI PMID:12839925 PMID:16278673 PMID:21411755 PMID:21436583 PMID:22617326 More... NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
increased granulosa cell tumor incidence term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amhr2 anti-Mullerian hormone type 2 receptor IAGP MGI PMID:8895659 PMID:18687666 PMID:19237610 PMID:19819941 PMID:21860425 More... NCBI chr15:102,353,437...102,363,075
Ensembl chr15:102,353,802...102,363,068 		JBrowse link
G Apc APC, WNT signaling pathway regulator IAGP MGI PMID:24474556 NCBI chr18:34,353,350...34,455,243
Ensembl chr18:34,353,977...34,455,605 		JBrowse link
G Atad5 ATPase family, AAA domain containing 5 IAGP MGI PMID:21901109 NCBI chr11:79,980,205...80,026,623
Ensembl chr11:79,980,226...80,026,620 		JBrowse link
G Bap1 Brca1 associated protein 1 IAGP MGI PMID:26896281 NCBI chr14:30,973,358...30,981,887
Ensembl chr14:30,973,407...30,981,901 		JBrowse link
G Bin1 bridging integrator 1 IAGP MGI PMID:17210688 NCBI chr18:32,509,671...32,568,793
Ensembl chr18:32,510,283...32,568,790 		JBrowse link
G Ctnnb1 catenin beta 1 IAGP MGI PMID:19237610 PMID:21860425 NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573 		JBrowse link
G Fancf Fanconi anemia, complementation group F IAGP MGI PMID:21915857 NCBI chr 7:51,510,325...51,512,015
Ensembl chr 7:51,510,325...51,512,015 		JBrowse link
G Foxo1 forkhead box O1 IAGP MGI PMID:26061565 NCBI chr 3:52,175,758...52,257,530
Ensembl chr 3:52,175,757...52,260,642 		JBrowse link
G Foxo3 forkhead box O3 IAGP MGI PMID:26061565 NCBI chr10:42,057,841...42,152,691
Ensembl chr10:42,057,837...42,152,751 		JBrowse link
G Helq helicase, POLQ-like IAGP MGI PMID:24005329 NCBI chr 5:100,910,010...100,946,529
Ensembl chr 5:100,910,011...100,946,464 		JBrowse link
G Inha inhibin alpha IAGP MGI PMID:8895659 NCBI chr 1:75,483,872...75,487,010
Ensembl chr 1:75,483,721...75,487,010 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase IAGP MGI PMID:27354067 NCBI chr 5:75,735,647...75,817,382
Ensembl chr 5:75,735,576...75,817,382 		JBrowse link
G Kras Kirsten rat sarcoma viral oncogene homolog IAGP MGI PMID:21860425 NCBI chr 6:145,162,425...145,197,631
Ensembl chr 6:145,162,425...145,195,965 		JBrowse link
G Msh5 mutS homolog 5 IAGP MGI PMID:21915857 NCBI chr17:35,247,581...35,267,842
Ensembl chr17:35,247,581...35,265,721 		JBrowse link
G Pgr progesterone receptor IAGP MGI PMID:24474556 NCBI chr 9:8,890,017...8,968,612
Ensembl chr 9:8,899,834...8,968,612 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha IAGP MGI PMID:22214849 NCBI chr 3:32,451,203...32,520,256
Ensembl chr 3:32,451,820...32,522,635 		JBrowse link
G Pten phosphatase and tensin homolog IAGP MGI PMID:18687666 PMID:19237610 PMID:21860425 PMID:22214849 PMID:25815421 More... NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560 		JBrowse link
G Smad1 SMAD family member 1 IAGP MGI PMID:19819941 NCBI chr 8:80,065,024...80,126,057
Ensembl chr 8:80,065,024...80,126,147 		JBrowse link
G Smad5 SMAD family member 5 IAGP MGI PMID:19819941 NCBI chr13:56,850,804...56,890,191
Ensembl chr13:56,850,823...56,890,190 		JBrowse link
G Trp53 transformation related protein 53 IAGP MGI PMID:25815421 PMID:27354067 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
increased ovarian carcinoma incidence term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amhr2 anti-Mullerian hormone type 2 receptor IAGP MGI PMID:17967875 PMID:22331912 PMID:25815421 NCBI chr15:102,353,437...102,363,075
Ensembl chr15:102,353,802...102,363,068 		JBrowse link
G Apc APC, WNT signaling pathway regulator IAGP MGI PMID:17418409 NCBI chr18:34,353,350...34,455,243
Ensembl chr18:34,353,977...34,455,605 		JBrowse link
G Arid1a AT-rich interaction domain 1A IAGP MGI PMID:25625625 NCBI chr 4:133,406,319...133,484,682
Ensembl chr 4:133,406,319...133,484,080 		JBrowse link
G Brca1 breast cancer 1, early onset IAGP MGI PMID:22617326 NCBI chr11:101,379,587...101,442,808
Ensembl chr11:101,379,590...101,442,781 		JBrowse link
G Ccdc80 coiled-coil domain containing 80 IAGP MGI PMID:25497869 NCBI chr16:44,913,770...44,948,287
Ensembl chr16:44,913,765...44,948,440 		JBrowse link
G Csf2 colony stimulating factor 2 (granulocyte-macrophage) IAGP MGI PMID:12732663 NCBI chr11:54,138,096...54,140,725
Ensembl chr11:54,138,097...54,140,493 		JBrowse link
G Dicer1 dicer 1, ribonuclease type III IAGP MGI PMID:22331912 PMID:25815421 NCBI chr12:104,654,001...104,718,331
Ensembl chr12:104,654,001...104,718,211 		JBrowse link
G Fshr follicle stimulating hormone receptor IAGP MGI PMID:11459817 NCBI chr17:89,292,380...89,508,103
Ensembl chr17:89,292,380...89,508,103 		JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:25625625 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,054,294 		JBrowse link
G Ifng interferon gamma IAGP MGI PMID:12732663 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797 		JBrowse link
G Pten phosphatase and tensin homolog IAGP MGI PMID:17418409 PMID:22331912 PMID:25815421 NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560 		JBrowse link
G Rb1 RB transcriptional corepressor 1 IAGP MGI PMID:12839925 NCBI chr14:73,430,298...73,563,446
Ensembl chr14:73,421,113...73,563,262 		JBrowse link
G Smad1 SMAD family member 1 IAGP MGI PMID:17967875 NCBI chr 8:80,065,024...80,126,057
Ensembl chr 8:80,065,024...80,126,147 		JBrowse link
G Smad5 SMAD family member 5 IAGP MGI PMID:17967875 NCBI chr13:56,850,804...56,890,191
Ensembl chr13:56,850,823...56,890,190 		JBrowse link
G Smad9 SMAD family member 9 IAGP MGI PMID:17967875 NCBI chr 3:54,662,873...54,709,162
Ensembl chr 3:54,663,003...54,708,678 		JBrowse link
G Trp53 transformation related protein 53 IAGP MGI PMID:12839925 PMID:22617326 PMID:25815421 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
increased ovarian teratoma incidence term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dclre1a DNA cross-link repair 1A IAGP MGI PMID:16260620 NCBI chr19:56,517,593...56,536,716
Ensembl chr19:56,517,599...56,536,675 		JBrowse link
G Foxo3 forkhead box O3 IAGP MGI PMID:17254969 PMID:21347845 NCBI chr10:42,057,841...42,152,691
Ensembl chr10:42,057,837...42,152,751 		JBrowse link
G Foxo4 forkhead box O4 IAGP MGI PMID:17254969 NCBI chr  X:100,297,855...100,304,479
Ensembl chr  X:100,298,134...100,304,479 		JBrowse link
G Trp53 transformation related protein 53 IAGP MGI PMID:23741457 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
increased ovary adenoma incidence term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amhr2 anti-Mullerian hormone type 2 receptor IAGP MGI PMID:27354067 NCBI chr15:102,353,437...102,363,075
Ensembl chr15:102,353,802...102,363,068 		JBrowse link
G Cdk5rap2 CDK5 regulatory subunit associated protein 2 IEA MGI NCBI chr 4:70,135,092...70,328,672
Ensembl chr 4:70,135,093...70,328,680 		JBrowse link
G Cdkn1b cyclin dependent kinase inhibitor 1B IAGP MGI PMID:27354067 NCBI chr 6:134,897,364...134,902,488
Ensembl chr 6:134,897,364...134,902,476 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase IAGP MGI PMID:27354067 NCBI chr 5:75,735,647...75,817,382
Ensembl chr 5:75,735,576...75,817,382 		JBrowse link
G Mcm8 minichromosome maintenance 8 homologous recombination repair factor IAGP MGI PMID:22771120 NCBI chr 2:132,658,061...132,686,117
Ensembl chr 2:132,658,061...132,686,117 		JBrowse link
G Trp53 transformation related protein 53 IAGP MGI PMID:27354067 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16756
    endocrine/exocrine gland phenotype 3413
      abnormal gland morphology 3175
        increased gland tumor incidence 344
          increased ovary tumor incidence 65
            increased granulosa cell tumor incidence 27
            increased ovarian carcinoma incidence 16
            increased ovarian fibroma incidence 0
            increased ovarian teratoma incidence 4
            increased ovary adenoma incidence 6
Path 2
Term Annotations click to browse term
  mammalian phenotype 16756
    neoplasm 1342
      abnormal tumor susceptibility 1202
        abnormal tumor incidence 1181
          abnormal organ/body region tumor incidence 892
            increased organ/body region tumor incidence 849
              increased reproductive system tumor incidence 127
                increased gonad tumor incidence 86
                  increased ovary tumor incidence 65
                    increased granulosa cell tumor incidence 27
                    increased ovarian carcinoma incidence 16
                    increased ovarian fibroma incidence 0
                    increased ovarian teratoma incidence 4
                    increased ovary adenoma incidence 6
paths to the root