Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (1->4)-beta-D-glucan | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of TOM1L2 mRNA | CTD | PMID:36331819 | (2,4,5-trichlorophenoxy)acetic acid | decreases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:18579281 | 1,2-dimethylhydrazine | decreases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of TOM1L2 mRNA | CTD | PMID:22206623 | 17beta-estradiol | increases expression | ISO | Tom1l2 (Rattus norvegicus) | 6480464 | Estradiol results in increased expression of TOM1L2 mRNA | CTD | PMID:35192832 | 2,3',4,4',5-Pentachlorobiphenyl | increases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:31388691 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Tom1l2 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of TOM1L2 mRNA | CTD | PMID:22298810 | 2-hydroxypropanoic acid | decreases expression | ISO | TOM1L2 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of TOM1L2 mRNA | CTD | PMID:30851411 | 4,4'-sulfonyldiphenol | decreases methylation | ISO | TOM1L2 (Homo sapiens) | 6480464 | bisphenol S results in decreased methylation of TOM1L2 gene | CTD | PMID:31601247 | 4,4'-sulfonyldiphenol | affects methylation | EXP | | 6480464 | bisphenol S affects the methylation of TOM1L2 gene | CTD | PMID:31683443 | 6-propyl-2-thiouracil | decreases expression | ISO | Tom1l2 (Rattus norvegicus) | 6480464 | Propylthiouracil results in decreased expression of TOM1L2 mRNA | CTD | PMID:30047161 | acetamide | decreases expression | ISO | Tom1l2 (Rattus norvegicus) | 6480464 | acetamide results in decreased expression of TOM1L2 mRNA | CTD | PMID:31881176 | aldrin | decreases expression | EXP | | 6480464 | Aldrin results in decreased expression of TOM1L2 mRNA | CTD | PMID:18579281 | all-trans-retinoic acid | increases expression | ISO | TOM1L2 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of TOM1L2 mRNA | CTD | PMID:23724009 and PMID:33167477 | antirheumatic drug | increases expression | ISO | TOM1L2 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of TOM1L2 mRNA | CTD | PMID:24449571 | aristolochic acid A | increases expression | ISO | TOM1L2 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of TOM1L2 mRNA | CTD | PMID:33212167 | arsane | multiple interactions | ISO | TOM1L2 (Homo sapiens) | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of TOM1L2 mRNA | CTD | PMID:32525701 | arsenic atom | multiple interactions | ISO | TOM1L2 (Homo sapiens) | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of TOM1L2 mRNA | CTD | PMID:32525701 | benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzo(a)pyrene results in decreased expression of TOM1L2 mRNA | CTD | PMID:22228805 | benzo[a]pyrene | affects methylation | ISO | TOM1L2 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of TOM1L2 intron | CTD | PMID:30157460 | benzo[a]pyrene | increases methylation | ISO | TOM1L2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of TOM1L2 promoter | CTD | PMID:27901495 | benzo[a]pyrene | decreases expression | ISO | TOM1L2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of TOM1L2 mRNA and Benzo(a)pyrene results in decreased expression of TOM1L2 protein | CTD | PMID:22316170 more ... | beta-naphthoflavone | decreases expression | ISO | TOM1L2 (Homo sapiens) | 6480464 | beta-Naphthoflavone results in decreased expression of TOM1L2 mRNA | CTD | PMID:32858204 | bisphenol A | decreases expression | ISO | Tom1l2 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of TOM1L2 mRNA | CTD | PMID:25181051 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of TOM1L2 mRNA | CTD | PMID:33221593 | Bisphenol B | increases expression | ISO | TOM1L2 (Homo sapiens) | 6480464 | bisphenol B results in increased expression of TOM1L2 protein | CTD | PMID:34186270 | Brodifacoum | decreases expression | ISO | Tom1l2 (Rattus norvegicus) | 6480464 | bromfenacoum results in decreased expression of TOM1L2 protein | CTD | PMID:28903499 | bromobenzene | increases expression | ISO | Tom1l2 (Rattus norvegicus) | 6480464 | bromobenzene results in increased expression of TOM1L2 mRNA | CTD | PMID:32479839 | caffeine | decreases phosphorylation | ISO | TOM1L2 (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of TOM1L2 protein | CTD | PMID:35688186 | carbon nanotube | decreases expression | EXP | | 6480464 | Nanotubes and Carbon analog results in decreased expression of TOM1L2 mRNA | CTD | PMID:25554681 | CGP 52608 | multiple interactions | ISO | TOM1L2 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to TOM1L2 gene] | CTD | PMID:28238834 | chloroethene | decreases expression | EXP | | 6480464 | Vinyl Chloride results in decreased expression of TOM1L2 mRNA | CTD | PMID:18579281 | copper(II) sulfate | increases expression | ISO | TOM1L2 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of TOM1L2 mRNA | CTD | PMID:19549813 | copper(II) sulfate | decreases expression | EXP | | 6480464 | Copper Sulfate results in decreased expression of TOM1L2 mRNA | CTD | PMID:18579281 | dexamethasone | increases expression | ISO | TOM1L2 (Homo sapiens) | 6480464 | Dexamethasone results in increased expression of TOM1L2 mRNA | CTD | PMID:25047013 | disodium selenite | increases expression | ISO | TOM1L2 (Homo sapiens) | 6480464 | Sodium Selenite results in increased expression of TOM1L2 mRNA | CTD | PMID:18175754 | epoxiconazole | decreases expression | EXP | | 6480464 | epoxiconazole results in decreased expression of TOM1L2 mRNA | CTD | PMID:35436446 | ethanol | affects splicing | EXP | | 6480464 | Ethanol affects the splicing of TOM1L2 mRNA | CTD | PMID:30319688 | fipronil | increases expression | ISO | Tom1l2 (Rattus norvegicus) | 6480464 | fipronil results in increased expression of TOM1L2 mRNA | CTD | PMID:34044035 | gentamycin | increases expression | ISO | Tom1l2 (Rattus norvegicus) | 6480464 | Gentamicins results in increased expression of TOM1L2 mRNA | CTD | PMID:33387578 | hydrogen peroxide | affects expression | ISO | TOM1L2 (Homo sapiens) | 6480464 | Hydrogen Peroxide affects the expression of TOM1L2 mRNA | CTD | PMID:20044591 | inulin | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of TOM1L2 mRNA | CTD | PMID:36331819 | ivermectin | decreases expression | ISO | TOM1L2 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of TOM1L2 protein | CTD | PMID:32959892 | methimazole | decreases expression | ISO | Tom1l2 (Rattus norvegicus) | 6480464 | Methimazole results in decreased expression of TOM1L2 mRNA | CTD | PMID:30047161 | ozone | multiple interactions | EXP | | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of TOM1L2 mRNA | CTD | PMID:34911549 | paracetamol | increases expression | ISO | TOM1L2 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of TOM1L2 mRNA | CTD | PMID:22230336 | paracetamol | increases expression | ISO | Tom1l2 (Rattus norvegicus) | 6480464 | Acetaminophen results in increased expression of TOM1L2 mRNA | CTD | PMID:33387578 | paracetamol | decreases expression | ISO | TOM1L2 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of TOM1L2 mRNA | CTD | PMID:26690555 | perfluorooctane-1-sulfonic acid | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of TOM1L2 mRNA and [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of TOM1L2 mRNA | CTD | PMID:36331819 | potassium dichromate | decreases expression | ISO | TOM1L2 (Homo sapiens) | 6480464 | Potassium Dichromate results in decreased expression of TOM1L2 protein | CTD | PMID:23718831 | rac-lactic acid | decreases expression | ISO | TOM1L2 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of TOM1L2 mRNA | CTD | PMID:30851411 | sodium arsenate | multiple interactions | ISO | TOM1L2 (Homo sapiens) | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of TOM1L2 mRNA | CTD | PMID:32525701 | trichostatin A | affects expression | ISO | TOM1L2 (Homo sapiens) | 6480464 | trichostatin A affects the expression of TOM1L2 mRNA | CTD | PMID:28542535 | triptonide | decreases expression | EXP | | 6480464 | triptonide results in decreased expression of TOM1L2 mRNA | CTD | PMID:33045310 | urethane | increases expression | ISO | TOM1L2 (Homo sapiens) | 6480464 | Urethane results in increased expression of TOM1L2 mRNA | CTD | PMID:28818685 | valproic acid | increases methylation | ISO | TOM1L2 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of TOM1L2 gene | CTD | PMID:29154799 | valproic acid | increases expression | ISO | TOM1L2 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of TOM1L2 mRNA | CTD | PMID:23179753 | valproic acid | decreases expression | ISO | TOM1L2 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of TOM1L2 mRNA | CTD | PMID:37505509 | |