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Gene: Mutyh (mutY DNA glycosylase) Mus musculus
Symbol: Mutyh
Name: mutY DNA glycosylase
Description: Predicted to have DNA N-glycosylase activity; DNA binding activity; and MutSalpha complex binding activity. Involved in negative regulation of necroptotic process. Localizes to mitochondrion. Human ortholog(s) of this gene implicated in familial adenomatous polyposis; familial adenomatous polyposis 2; and stomach carcinoma. Orthologous to human MUTYH (mutY DNA glycosylase); PARTICIPATES IN base excision repair pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 5730495A01Rik; A/G-specific adenine DNA glycosylase; adenine DNA glycosylase; adenine-DNA glycosylase; mMYH; mutY homolog alpha; Mutyha; Mutyhalpha; Mutyhb; Mutyhbeta; Mutyhc; Myh; the full-length form type A, 5' region
Homo sapiens (human) : MUTYH (mutY DNA glycosylase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Mutyh (mutY DNA glycosylase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mutyh (mutY DNA glycosylase)
Pan paniscus (bonobo/pygmy chimpanzee) : MUTYH (mutY DNA glycosylase)
Canis lupus familiaris (dog) : MUTYH (mutY DNA glycosylase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mutyh (mutY DNA glycosylase)
Sus scrofa (pig) : MUTYH (mutY DNA glycosylase)
Chlorocebus sabaeus (African green monkey) : MUTYH (mutY DNA glycosylase)
Heterocephalus glaber (naked mole-rat) : Mutyh (mutY DNA glycosylase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl4116,807,723 - 116,819,440 (+)EnsemblGRCm38mm10GRCm38
GRCm384116,807,636 - 116,819,439 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv374116,480,339 - 116,492,036 (+)NCBIGRCm37mm9NCBIm37
MGSCv364116,312,257 - 116,317,312 (+)NCBImm8
Celera4115,542,682 - 115,558,847 (+)NCBICelera
Cytogenetic Map4D1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Mutyh
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731075
Created: 2003-12-10
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.