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Gene: Mutyh (mutY DNA glycosylase) Mus musculus
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Symbol: Mutyh
Name: mutY DNA glycosylase
Description: Predicted to have DNA N-glycosylase activity; DNA binding activity; and MutSalpha complex binding activity. Involved in negative regulation of necroptotic process. Localizes to mitochondrion. Human ortholog(s) of this gene implicated in familial adenomatous polyposis; familial adenomatous polyposis 2; and stomach carcinoma. Orthologous to human MUTYH (mutY DNA glycosylase); PARTICIPATES IN base excision repair pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 5730495A01Rik; A/G-specific adenine DNA glycosylase; adenine DNA glycosylase; adenine-DNA glycosylase; mMYH; mutY homolog alpha; Mutyha; Mutyhalpha; Mutyhb; Mutyhbeta; Mutyhc; Myh; the full-length form type A, 5' region
Orthologs:
Homo sapiens (human) : MUTYH (mutY DNA glycosylase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Mutyh (mutY DNA glycosylase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mutyh (mutY DNA glycosylase)
Pan paniscus (bonobo/pygmy chimpanzee) : MUTYH (mutY DNA glycosylase)
Canis lupus familiaris (dog) : MUTYH (mutY DNA glycosylase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mutyh (mutY DNA glycosylase)
Sus scrofa (pig) : MUTYH (mutY DNA glycosylase)
Chlorocebus sabaeus (African green monkey) : MUTYH (mutY DNA glycosylase)
Heterocephalus glaber (naked mole-rat) : Mutyh (mutY DNA glycosylase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl4116,807,723 - 116,819,440 (+)EnsemblGRCm38mm10GRCm38
GRCm384116,807,636 - 116,819,439 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv374116,480,339 - 116,492,036 (+)NCBIGRCm37mm9NCBIm37
MGSCv364116,312,257 - 116,317,312 (+)NCBImm8
Celera4115,542,682 - 115,558,847 (+)NCBICelera
Cytogenetic Map4D1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Mutyh
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731075
Created: 2003-12-10
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.