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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:increased organ/body region tumor incidence
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Accession:MP:0010274 term browser browse the term
Definition:greater than the expected number of tumors originating in a specific body region or organ in a given population in a given time period
Synonyms:exact_synonym: increased organ/body region tumour incidence


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increased colon adenoma incidence term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway IMP compared to treated females, mock treated males RGD PMID:17360473 RGD:1601201 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696 		JBrowse link
G ApcPirc APC, WNT signaling pathway regulator; polyposis in the rat colon IMP compared to treated females, mock treated males RGD PMID:17360473 RGD:1601201
increased intestinal adenocarcinoma incidence term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway sexual_dimorphism IMP compared to treated females RGD PMID:17360473 RGD:1601201 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696 		JBrowse link
G ApcPirc APC, WNT signaling pathway regulator; polyposis in the rat colon sexual_dimorphism IMP compared to treated females RGD PMID:17360473 RGD:1601201
increased osteosarcoma incidence term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 IAGP DNA:deletion RGD PMID:19825367 RGD:5147850 NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897 		JBrowse link
increased pheochromocytoma incidence term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdkn1b cyclin-dependent kinase inhibitor 1B IAGP RGD PMID:12036912 RGD:619590 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Cdkn1bwe cyclin-dependent kinase inhibitor 1B; white eye mutation IAGP RGD PMID:12036912 RGD:619590
Term paths to the root
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Term Annotations click to browse term
  mammalian phenotype 5402
    neoplasm 244
      abnormal tumor susceptibility 236
        abnormal tumor incidence 225
          abnormal organ/body region tumor incidence 189
            increased organ/body region tumor incidence 139
              increased alimentary system tumor incidence + 28
              increased cardiovascular system tumor incidence + 0
              increased eye tumor incidence + 0
              increased gland tumor incidence + 86
              increased hemolymphoid system tumor incidence + 30
              increased hepatobiliary system tumor incidence + 11
              increased integument system tumor incidence + 56
              increased muscle tumor incidence + 1
              increased nervous system tumor incidence + 1
              increased reproductive system tumor incidence + 10
              increased respiratory system tumor incidence + 0
              increased reticular tumor incidence + 0
              increased skeletal tumor incidence + 1
              increased urinary system tumor incidence + 0
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