Ogg1 (8-oxoguanine DNA-glycosylase 1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Ogg1 (8-oxoguanine DNA-glycosylase 1) Mus musculus
Analyze
Symbol: Ogg1
Name: 8-oxoguanine DNA-glycosylase 1
RGD ID: 732766
MGI Page MGI
Description: Enables 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity and microtubule binding activity. Acts upstream of or within base-excision repair. Located in mitochondrion and nucleus. Human ortholog(s) of this gene implicated in several diseases, including Graves' disease; angiomyolipoma; carcinoma (multiple); eye disease (multiple); and reproductive organ cancer (multiple). Orthologous to human OGG1 (8-oxoguanine DNA glycosylase); PARTICIPATES IN base excision repair pathway; INTERACTS WITH (+)-dexrazoxane; 1,4-benzoquinone; 1H-pyrazole.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Mmh; N-glycosylase/DNA lyase
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396113,303,871 - 113,311,838 (+)NCBIGRCm39mm39
GRCm39 Ensembl6113,303,933 - 113,312,029 (+)Ensembl
GRCm386113,326,972 - 113,334,877 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6113,326,972 - 113,335,068 (+)EnsemblGRCm38mm10GRCm38
MGSCv376113,276,970 - 113,284,182 (+)NCBIGRCm37mm9NCBIm37
MGSCv366113,292,788 - 113,299,961 (+)NCBImm8
Celera6115,153,980 - 115,161,188 (+)NCBICelera
Cytogenetic Map6E3NCBI
cM Map652.75NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
adenocarcinoma  (ISO)
allergic contact dermatitis  (IMP)
angiomyolipoma  (ISO)
Atrioventricular Septal Defect 2  (ISO)
basal cell carcinoma  (ISO)
brain disease  (ISO)
breast cancer  (ISO)
cataract  (ISO)
cholangiocarcinoma  (ISO)
Chromosome Aberrations  (ISO)
clear cell renal cell carcinoma  (ISO)
developmental coordination disorder  (ISO)
Discoid Lupus Erythematosus  (ISO)
Endometrial Neoplasms  (ISO)
Experimental Diabetes Mellitus  (IMP,ISO)
Experimental Liver Cirrhosis  (ISO)
Gallbladder Neoplasms  (ISO)
Genetic Predisposition to Disease  (ISO)
Graves' disease  (ISO)
head and neck squamous cell carcinoma  (ISO)
Hearing Loss, Noise-Induced  (ISO)
heart disease  (ISO)
hepatitis  (ISO)
human immunodeficiency virus infectious disease  (ISO)
Huntington's disease  (ISO)
Hyperplasia  (ISO)
Kidney Reperfusion Injury  (ISO)
lung adenocarcinoma  (ISO)
Lung Neoplasms  (ISO)
Lymphatic Metastasis  (ISO)
lymphoma  (ISO)
male infertility  (ISO)
middle cerebral artery infarction  (ISO)
Nerve Degeneration  (ISO)
Neurodevelopmental Disorders  (ISO)
nonpapillary renal cell carcinoma  (ISO,ISS)
obesity  (ISO)
ovarian cancer  (ISO)
pancreatic cancer  (ISO)
Parkinson's disease  (ISO)
Premature Birth  (ISO)
Prenatal Exposure Delayed Effects  (ISO)
Prenatal Injuries  (ISO)
primary open angle glaucoma  (ISO)
progressive supranuclear palsy  (ISO)
prostate cancer  (ISO)
Prostatic Neoplasms  (ISO)
pterygium  (ISO)
renal cell carcinoma  (ISO)
sarcoma  (IMP)
senile cataract  (ISO)
skin disease  (ISO)
squamous cell carcinoma  (IMP)
status epilepticus  (ISO)
Tongue Neoplasms  (ISO)
toxic shock syndrome  (IMP)
transient cerebral ischemia  (ISO)
transitional cell carcinoma  (ISO)
type 2 diabetes mellitus  (ISO)
Urologic Neoplasms  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-dexrazoxane  (EXP)
(+)-pilocarpine  (ISO)
(S)-nicotine  (ISO)
1,1'-azobis(N,N-dimethylformamide)  (ISO)
1,2-dimethylhydrazine  (ISO)
1,4-benzoquinone  (EXP)
17beta-estradiol  (ISO)
1H-pyrazole  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2,4-dinitrotoluene  (ISO)
2,6-di-tert-butyl-4-methylphenol  (ISO)
2,6-diamino-5-formamido-4-hydroxypyrimidine  (EXP)
3,4-methylenedioxymethamphetamine  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-azacytidine  (EXP)
6-propyl-2-thiouracil  (ISO)
7,12-dimethyltetraphene  (ISO)
7,8-dihydro-8-oxoguanine  (EXP,ISO)
7,9-dihydro-1H-purine-2,6,8(3H)-trione  (EXP)
8-hydroxy-2'-deoxyguanosine  (ISO)
acrolein  (EXP,ISO)
acrylamide  (ISO)
aflatoxin B1  (EXP)
all-trans-retinoic acid  (ISO)
alpha-hexachlorocyclohexane  (ISO)
alpha-pinene  (ISO)
ammonium chloride  (ISO)
aniline  (ISO)
antirheumatic drug  (ISO)
aristolochic acid  (ISO)
Aroclor 1254  (EXP)
arsane  (EXP,ISO)
arsenic atom  (EXP,ISO)
arsenite(3-)  (EXP)
arsenous acid  (ISO)
aurintricarboxylic acid  (ISO)
belinostat  (EXP)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
beryllium dichloride  (EXP)
bezafibrate  (EXP)
biphenyl-4-amine  (ISO)
bisphenol A  (ISO)
bisphenol F  (ISO)
C60 fullerene  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
camphene  (ISO)
carbon atom  (EXP)
carmustine  (ISO)
chlorpyrifos  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
crocidolite asbestos  (EXP,ISO)
curcumin  (ISO)
cyclophosphamide  (EXP)
DDT  (ISO)
deoxynivalenol  (ISO)
dexamethasone  (ISO)
Diacetoxyscirpenol  (EXP)
diarsenic trioxide  (ISO)
diethyl maleate  (EXP)
dimethylarsinic acid  (EXP,ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elemental carbon  (EXP)
elemental selenium  (ISO)
entinostat  (ISO)
ethanol  (EXP,ISO)
etoposide  (EXP)
flutamide  (ISO)
furan  (ISO)
geraniol  (ISO)
glutathione  (EXP)
glycine betaine  (EXP)
glyphosate  (ISO)
gold atom  (ISO)
gold(0)  (ISO)
hydralazine  (ISO)
hydrazine  (EXP)
hydrazines  (ISO)
hydrogen peroxide  (ISO)
idarubicin  (EXP)
imidacloprid  (ISO)
indometacin  (ISO)
L-ascorbic acid  (ISO)
lead(0)  (EXP,ISO)
lead(2+)  (EXP,ISO)
lithium atom  (EXP)
lithium hydride  (EXP)
lupeol  (ISO)
mancozeb  (ISO)
manganese atom  (EXP)
manganese(0)  (EXP)
menadione  (ISO)
mercury atom  (EXP)
mercury(0)  (EXP)
metformin  (ISO)
methamphetamine  (EXP,ISO)
methyl tert-butyl ether  (ISO)
methylarsonic acid  (ISO)
miconazole  (ISO)
mitomycin C  (EXP)
monocrotophos  (ISO)
myristicin  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (ISO)
nickel atom  (EXP)
nicotine  (ISO)
nimesulide  (ISO)
O-methyleugenol  (ISO)
ochratoxin A  (ISO)
oxaliplatin  (ISO)
oxirane  (ISO)
ozone  (ISO)
paclitaxel  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
parathion-methyl  (EXP)
phenobarbital  (ISO)
piperonyl butoxide  (EXP)
potassium bromate  (EXP)
potassium dichromate  (ISO)
pristane  (EXP)
quartz  (ISO)
quercetin  (ISO)
reactive oxygen species  (ISO)
resveratrol  (ISO)
rosmarinic acid  (ISO)
S-adenosyl-L-homocysteine  (EXP)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (EXP)
SB 431542  (ISO)
SCH 23390  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (ISO)
Soman  (ISO)
styrene  (ISO)
tamibarotene  (ISO)
tert-butyl ethyl ether  (ISO)
tetrachloromethane  (EXP)
Thiotepa  (ISO)
Thymidine glycol  (ISO)
titanium dioxide  (ISO)
topotecan  (ISO)
tributylstannane  (ISO)
trimethylarsine oxide  (ISO)
valproic acid  (ISO)
vincristine  (ISO)
vorinostat  (EXP)
wogonin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
mitochondrion  (HDA,IMP,ISO)
nuclear matrix  (ISO)
nuclear speck  (ISO)
nucleoplasm  (ISO)
nucleus  (IBA,IMP,ISO)
protein-containing complex  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
1. Audebert M, etal., Cancer Res. 2000 Sep 1;60(17):4740-4.
2. Chen X, etal., Breast Cancer Res Treat. 2011 Jun;127(3):795-803. doi: 10.1007/s10549-010-1284-2. Epub 2010 Dec 14.
3. Choudhury S, etal., Cancer Res. 2003 Nov 15;63(22):7704-7.
4. Cincin ZB, etal., Med Oncol. 2012 Dec;29(4):2949-54. doi: 10.1007/s12032-012-0162-7. Epub 2012 Jan 22.
5. Cong W, etal., Zhonghua Bing Li Xue Za Zhi. 2001 Jun;30(3):183-7.
6. Cong WM, etal., J Cancer Res Clin Oncol. 2001;127(3):187-92.
7. Dhillon VS, etal., Urol Oncol. 2011 Nov-Dec;29(6):641-6. doi: 10.1016/j.urolonc.2009.08.013. Epub 2009 Nov 13.
8. Duell EJ, etal., Cancer Epidemiol Biomarkers Prev. 2008 Jun;17(6):1470-9.
9. Fleischer T, etal., Int J Cancer. 2014 Jun 1;134(11):2615-25. doi: 10.1002/ijc.28606. Epub 2014 Jan 6.
10. Fukae J, etal., Acta Neuropathol. 2005 Mar;109(3):256-62. Epub 2004 Nov 17.
11. Gharib AF, etal., Mol Vis. 2014 May 21;20:661-9. eCollection 2014.
12. Habib SL Mol Cancer. 2009 Mar 5;8:13. doi: 10.1186/1476-4598-8-13.
13. Habib SL, etal., Cancer Biol Ther. 2008 Jan;7(1):23-7. Epub 2007 Oct 8.
14. Habib SL, etal., Mol Cancer. 2008 Jan 24;7:10.
15. He M, etal., Brain Res. 2007 Nov 21;1181:83-92. Epub 2007 Sep 8.
16. Huang XX, etal., Mol Genet Metab. 2012 May;106(1):127-30. doi: 10.1016/j.ymgme.2012.02.017. Epub 2012 Mar 3.
17. Hung RJ, etal., Am J Epidemiol. 2005 Nov 15;162(10):925-42. Epub 2005 Oct 12.
18. Ichikawa K, etal., Mol Biol Rep. 2012 Dec;39(12):10803-10. doi: 10.1007/s11033-012-1974-4. Epub 2012 Oct 9.
19. Jarrett SG, etal., Neurobiol Dis. 2008 Apr;30(1):130-8. Epub 2008 Jan 5.
20. Kau HC, etal., Eye (Lond). 2004 Jun;18(6):635-9.
21. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
22. Kim KY, etal., Gene. 2013 Dec 15;532(2):192-6. doi: 10.1016/j.gene.2013.09.069. Epub 2013 Sep 25.
23. Ku YP, etal., Acta Histochem. 2009;111(2):138-44. Epub 2008 Aug 3.
24. Kumar A, etal., Tumour Biol. 2012 Feb;33(1):111-9. doi: 10.1007/s13277-011-0253-7. Epub 2011 Nov 15.
25. Kunisada M, etal., Cancer Res. 2005 Jul 15;65(14):6006-10.
26. Lan J, etal., J Cereb Blood Flow Metab. 2003 Nov;23(11):1324-39.
27. Li D, etal., Int J Cancer. 2007 Apr 15;120(8):1748-54.
28. Li D, etal., Mol Carcinog. 2001 Aug;31(4):214-23.
29. Luo H, etal., Asian Pac J Cancer Prev. 2014;15(3):1133-40.
30. Mabley JG, etal., FASEB J. 2005 Feb;19(2):290-2. Epub 2004 Dec 1.
31. MGD data from the GO Consortium
32. MGD IEA
33. Ming-Shiean H, etal., Ann Surg Oncol. 2010 Mar;17(3):760-71.
34. Mitra AK, etal., Indian J Med Res. 2011 Jun;133:605-12.
35. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
36. OMIM Disease Annotation Pipeline
37. Osorio A, etal., PLoS Genet. 2014 Apr 3;10(4):e1004256. doi: 10.1371/journal.pgen.1004256. eCollection 2014 Apr.
38. Pipeline to import KEGG annotations from KEGG into RGD
39. RGD automated import pipeline
40. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
41. RGD automated import pipeline for gene-chemical interactions
42. Rossner P Jr, etal., Cancer Epidemiol Biomarkers Prev. 2006 Apr;15(4):811-5.
43. Shen H, etal., PLoS One. 2014 Mar 5;9(3):e89662. doi: 10.1371/journal.pone.0089662. eCollection 2014.
44. Shpitzer T, etal., Br J Cancer. 2009 Oct 6;101(7):1194-8. doi: 10.1038/sj.bjc.6605290.
45. Simone S, etal., Diabetes. 2008 Oct;57(10):2626-36. doi: 10.2337/db07-1579. Epub 2008 Jul 3.
46. Sobczuk A, etal., Pathol Oncol Res. 2012 Oct;18(4):1015-20. Epub 2012 Apr 28.
47. Srivastava A, etal., Ann Surg Oncol. 2009 Jun;16(6):1695-703. Epub 2009 Mar 6.
48. Srivastava K, etal., Cancer. 2010 Jul 1;116(13):3160-9. doi: 10.1002/cncr.25063.
49. Synowiec E, etal., Mutat Res. 2008 Dec 15;648(1-2):65-72. doi: 10.1016/j.mrfmmm.2008.09.014. Epub 2008 Oct 10.
50. Szaflik JP, etal., Mutat Res. 2013 Apr 30;753(1):12-22. doi: 10.1016/j.mrgentox.2012.12.019. Epub 2013 Mar 7.
51. Tanrikulu S, etal., Cell Biochem Funct. 2011 Apr;29(3):244-8. doi: 10.1002/cbf.1742. Epub 2011 Feb 24.
52. Tsuruya K, etal., DNA Repair (Amst). 2003 Feb 3;2(2):211-29.
53. Tyrberg B, etal., BMC Endocr Disord. 2002 Apr 25;2(1):2.
54. Vogel U, etal., Cancer Epidemiol Biomarkers Prev. 2004 Oct;13(10):1680-1.
55. Wang YH, etal., Anticancer Res. 2011 Nov;31(11):3939-44.
56. Zhang Y, etal., Cancer Epidemiol Biomarkers Prev. 2006 Feb;15(2):353-8.
57. Zhang Y, etal., Ophthalmology. 2012 May;119(5):900-6. doi: 10.1016/j.ophtha.2011.11.004. Epub 2012 Feb 4.
58. Zhou C, etal., Biomed Rep. 2013 Jul;1(4):679-683. Epub 2013 May 30.
Additional References at PubMed
PMID:7311623   PMID:8889548   PMID:9088907   PMID:9187114   PMID:9197244   PMID:9207108   PMID:9321410   PMID:9434942   PMID:10098454   PMID:10349636   PMID:10515589   PMID:10557315  
PMID:10570187   PMID:10725358   PMID:10727854   PMID:10775435   PMID:11042159   PMID:11076861   PMID:11369503   PMID:11454679   PMID:11532868   PMID:12200441   PMID:12447686   PMID:12477932  
PMID:12507922   PMID:12615700   PMID:12644468   PMID:12691525   PMID:12759433   PMID:12819227   PMID:12874039   PMID:12904583   PMID:14610273   PMID:14651853   PMID:15126346   PMID:15199168  
PMID:15231648   PMID:15474421   PMID:15721984   PMID:15725623   PMID:15778095   PMID:15782199   PMID:16141072   PMID:16141073   PMID:16221681   PMID:16358418   PMID:16369492   PMID:16478987  
PMID:16494984   PMID:16765995   PMID:16961812   PMID:17003489   PMID:17213818   PMID:17425590   PMID:17441966   PMID:17450122   PMID:17545594   PMID:17675188   PMID:17971305   PMID:17989114  
PMID:18006041   PMID:18258604   PMID:18300266   PMID:18614015   PMID:18768699   PMID:19020090   PMID:19061977   PMID:19389114   PMID:19503746   PMID:19506022   PMID:19594329   PMID:19997493  
PMID:20026424   PMID:20042377   PMID:20067321   PMID:20118626   PMID:20360068   PMID:20485567   PMID:20498273   PMID:20736962   PMID:20956573   PMID:21062970   PMID:21267068   PMID:21322094  
PMID:21505090   PMID:21566259   PMID:21677750   PMID:21715639   PMID:21778470   PMID:21873635   PMID:22001346   PMID:22057269   PMID:22100973   PMID:22209780   PMID:22523232   PMID:22536455  
PMID:23127499   PMID:23143307   PMID:23284747   PMID:23355608   PMID:23566953   PMID:23603834   PMID:23612479   PMID:23748360   PMID:23813448   PMID:24121118   PMID:24291244   PMID:24296244  
PMID:24304833   PMID:24429287   PMID:24489103   PMID:24681335   PMID:24732403   PMID:24732879   PMID:24918270   PMID:25113976   PMID:25267977   PMID:25308545   PMID:25311828   PMID:25583175  
PMID:25614460   PMID:26210637   PMID:26247199   PMID:26401913   PMID:26496208   PMID:26586787   PMID:26711335   PMID:27251462   PMID:27343030   PMID:27384322   PMID:27581360   PMID:27596356  
PMID:27756845   PMID:27816939   PMID:28127763   PMID:28202616   PMID:28266569   PMID:28727777   PMID:28820464   PMID:28843610   PMID:29101721   PMID:29207315   PMID:29409673   PMID:29540303  
PMID:29795387   PMID:29860357   PMID:30291284   PMID:31284385   PMID:31311771   PMID:31935236   PMID:32209025   PMID:32424276   PMID:32585298   PMID:32808374   PMID:32929043   PMID:33503804  


Genomics

Comparative Map Data
Ogg1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396113,303,871 - 113,311,838 (+)NCBIGRCm39mm39
GRCm39 Ensembl6113,303,933 - 113,312,029 (+)Ensembl
GRCm386113,326,972 - 113,334,877 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6113,326,972 - 113,335,068 (+)EnsemblGRCm38mm10GRCm38
MGSCv376113,276,970 - 113,284,182 (+)NCBIGRCm37mm9NCBIm37
MGSCv366113,292,788 - 113,299,961 (+)NCBImm8
Celera6115,153,980 - 115,161,188 (+)NCBICelera
Cytogenetic Map6E3NCBI
cM Map652.75NCBI
OGG1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl39,749,944 - 9,788,219 (+)EnsemblGRCh38hg38GRCh38
GRCh3839,749,952 - 9,788,246 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3739,791,636 - 9,808,334 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3639,765,705 - 9,783,342 (+)NCBINCBI36hg18NCBI36
Build 3439,766,653 - 9,783,311NCBI
Celera39,726,330 - 9,743,054 (+)NCBI
Cytogenetic Map3p25.3NCBI
HuRef39,727,975 - 9,744,701 (+)NCBIHuRef
CHM1_139,741,823 - 9,758,548 (+)NCBICHM1_1
Ogg1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24146,474,701 - 146,481,959 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl4146,474,750 - 146,484,766 (+)Ensembl
Rnor_6.04145,282,828 - 145,289,367 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4145,282,797 - 145,289,326 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04208,580,193 - 208,586,457 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44149,209,745 - 149,219,081 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14149,454,585 - 149,463,922 (+)NCBI
Celera4135,032,266 - 135,038,520 (+)NCBICelera
Cytogenetic Map4q42NCBI
Ogg1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555611,277,365 - 1,282,793 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555611,277,362 - 1,282,949 (+)NCBIChiLan1.0ChiLan1.0
OGG1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.139,940,955 - 9,972,658 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl39,940,955 - 9,947,335 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v039,702,311 - 9,742,283 (+)NCBIMhudiblu_PPA_v0panPan3
OGG1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1208,486,150 - 8,491,448 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl208,480,005 - 8,491,264 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha208,519,224 - 8,524,513 (-)NCBI
ROS_Cfam_1.0208,515,436 - 8,520,730 (-)NCBI
UMICH_Zoey_3.1208,237,911 - 8,243,202 (-)NCBI
UNSW_CanFamBas_1.0208,582,435 - 8,587,727 (-)NCBI
UU_Cfam_GSD_1.0208,556,049 - 8,561,340 (-)NCBI
Ogg1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494215,490,887 - 15,501,164 (+)NCBI
SpeTri2.0NW_0049366023,411,106 - 3,418,826 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
OGG1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11366,038,669 - 66,045,478 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21373,102,660 - 73,108,902 (-)NCBISscrofa10.2Sscrofa10.2susScr3
OGG1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12245,757,414 - 45,763,690 (+)NCBI
Vero_WHO_p1.0NW_023666041120,772,448 - 120,811,082 (-)NCBI
Ogg1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247314,383,000 - 4,388,486 (+)NCBI

Position Markers
AI505105  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386113,334,193 - 113,334,325UniSTSGRCm38
MGSCv376113,284,187 - 113,284,319UniSTSGRCm37
Celera6115,161,193 - 115,161,325UniSTS
Cytogenetic Map6E-F1UniSTS
Cytogenetic Map6E3UniSTS
cM Map648.7UniSTS
Whitehead/MRC_RH61161.76UniSTS
D6Ertd263e  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386113,334,160 - 113,334,384UniSTSGRCm38
MGSCv376113,284,154 - 113,284,378UniSTSGRCm37
Celera6115,161,160 - 115,161,384UniSTS
Cytogenetic Map6E3UniSTS
Cytogenetic Map6E-F1UniSTS
cM Map648.7UniSTS
Ogg1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386113,331,816 - 113,333,367UniSTSGRCm38
MGSCv376113,281,810 - 113,283,361UniSTSGRCm37
Celera6115,158,816 - 115,160,367UniSTS
Cytogenetic Map6E-F1UniSTS
cM Map648.0UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301687Mnic2_mmacronutrient intake (mouse)Not determined686806805113544602Mouse
1301744Hdlq11_mHDL QTL 11 (mouse)Not determined687503360121503555Mouse
1301509Sluc3_msusceptibility to lung cancer 3 (mouse)Not determined6104503360127042975Mouse
1301518Bbaa5_mB.burgdorferi-associated arthritis 5 (mouse)Not determined698506837145935444Mouse
1301962Eila2_methanol induced locomotor activity 2 (mouse)Not determined648726556125356785Mouse
4141376Dbm1_mdiabetes modifier 1 (mouse)Not determined678629504121115387Mouse
1301915Chab3_mcholesterol absorption 3 (mouse)Not determined698931748132940036Mouse
1300887Pabr1_mplasma apolipoprotein B (human) regulator 1 (mouse)Not determined6103777444136423692Mouse
1301923Lith6_mlithogenic gene 6 (mouse)Not determined698717516132717715Mouse
1357683Igf1sl1_mIGF-1 serum levels 1 (mouse)Not determined652161713116155267Mouse
1357555Tesq2_mtestis weight QTL 2 (mouse)Not determined696655951146633626Mouse
1302131Bmd8_mbone mineral density 8 (mouse)Not determined699155128133155267Mouse
1300704Cia3_mcollagen induced arthritis QTL 3 (mouse)Not determined696347325130347522Mouse
1357793Pnhdlc1_mplasma non-HDL cholesterol 1 (mouse)Not determined6105564822114368849Mouse
1357806Aaj3_manxiety in A/J 3 (mouse)Not determined6104503360136423692Mouse
1301244Ichs_mimmediate cutaneous hypersensitivity QTL (mouse)Not determined690795610124795846Mouse
1301262Gasa3_mgastritis type A susceptibility locus 3 (mouse)Not determined689005405123005603Mouse
1301292Cfbw2_mcystic fibrosis body weight 2 (mouse)Not determined695004651129004738Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46935985136423692Mouse
4141699Ibdq2_minflammatory bowel disease QTL 2 (mouse)Not determined106005405120917141Mouse
4142416Egq11_mearly growth QTL 11 (mouse)Not determined96655951146633626Mouse
10043864T2dm4sa_mtype 2 diabetes mellitus 4 in SMXA RI mice (mouse)Not determined683713869147052561Mouse
10043891Tilss4_mTNF-induced lethal shock susceptibility 3 (mouse)Not determined6112269957125356785Mouse
10043923Bhr7_mbronchial hyperresponsiveness 7 (mouse)Not determined698242853132242977Mouse
10412157Fl1n_mfatty liver 1 in NSY (mouse)Not determined645314059128835032Mouse
10412207Cypr5_mcytokine production 5 (mouse)Not determined6110838217144838360Mouse
4141940W6q5_mweight 6 weeks QTL 5 (mouse)Not determined96655951146633626Mouse
25440480Moaq2_mmodifier of alien QTL 2 (mouse)61117500000Mouse
25314319Histh6_mhistamine hypersensitivity 6 (mouse)648720000125360000Mouse
13506930Recrq9_mrecombination rate in male meiosis QTL 9 (mouse)673500000134700000Mouse
11353842Bmiq4_mbody mass index QTL 4 (mouse)692607306146429238Mouse
13463481Mcvq14_mmean corpuscular volume QTL 14 (mouse)6111165485145165578Mouse
11252138Clas1_mcarcinogen-induced lung adenoma susceptibility 1 (mouse)6112269957147052561Mouse
11040599Lmr4b_mleishmaniasis resistance 4b (mouse)696347325130347522Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139100000Mouse
11251720Ewc4_methanol withdrawal and consumption 4 (mouse)684122513118122513Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648720000148450000Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:658
Count of miRNA genes:406
Interacting mature miRNAs:476
Transcripts:ENSMUST00000032406, ENSMUST00000129871, ENSMUST00000136263, ENSMUST00000147945, ENSMUST00000154350
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_010957 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_149720 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006505720 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006505722 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC155287 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF000669 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF003596 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH005779 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ001307 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK008192 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK146870 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK165875 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK167456 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK181469 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK218768 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW048681 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY389525 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY389526 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY389527 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC138733 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC138736 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U88621 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U96711 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y11247 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y13479 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000032406   ⟹   ENSMUSP00000032406
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6113,303,933 - 113,311,149 (+)Ensembl
GRCm38.p6 Ensembl6113,326,972 - 113,334,188 (+)Ensembl
RefSeq Acc Id: ENSMUST00000129871
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6113,303,946 - 113,305,784 (+)Ensembl
GRCm38.p6 Ensembl6113,326,985 - 113,328,823 (+)Ensembl
RefSeq Acc Id: ENSMUST00000136263   ⟹   ENSMUSP00000144792
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6113,303,960 - 113,311,145 (+)Ensembl
GRCm38.p6 Ensembl6113,326,999 - 113,334,184 (+)Ensembl
RefSeq Acc Id: ENSMUST00000147945
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6113,310,279 - 113,312,029 (+)Ensembl
GRCm38.p6 Ensembl6113,333,318 - 113,335,068 (+)Ensembl
RefSeq Acc Id: ENSMUST00000154350
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6113,303,969 - 113,306,291 (+)Ensembl
GRCm38.p6 Ensembl6113,327,008 - 113,329,330 (+)Ensembl
RefSeq Acc Id: ENSMUST00000203721
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6113,304,072 - 113,305,915 (+)Ensembl
GRCm38.p6 Ensembl6113,327,111 - 113,328,954 (+)Ensembl
RefSeq Acc Id: ENSMUST00000204834   ⟹   ENSMUSP00000144905
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6113,303,974 - 113,310,946 (+)Ensembl
GRCm38.p6 Ensembl6113,327,013 - 113,333,985 (+)Ensembl
RefSeq Acc Id: NM_010957   ⟹   NP_035087
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396113,303,937 - 113,311,149 (+)NCBI
GRCm386113,326,976 - 113,334,188 (+)ENTREZGENE
MGSCv376113,276,970 - 113,284,182 (+)RGD
Celera6115,153,980 - 115,161,188 (+)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: NR_149720
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396113,303,937 - 113,311,149 (+)NCBI
GRCm386113,326,976 - 113,334,188 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006505720   ⟹   XP_006505783
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396113,303,871 - 113,311,838 (+)NCBI
GRCm386113,326,972 - 113,334,877 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006505722   ⟹   XP_006505785
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396113,303,936 - 113,311,838 (+)NCBI
GRCm386113,326,976 - 113,334,877 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_035087   ⟸   NM_010957
- UniProtKB: O08760 (UniProtKB/Swiss-Prot),   Q3UIL3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006505783   ⟸   XM_006505720
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006505785   ⟸   XM_006505722
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSMUSP00000032406   ⟸   ENSMUST00000032406
RefSeq Acc Id: ENSMUSP00000144905   ⟸   ENSMUST00000204834
RefSeq Acc Id: ENSMUSP00000144792   ⟸   ENSMUST00000136263
Protein Domains
ENDO3c   OGG_N

Promoters
RGD ID:6839752
Promoter ID:MM_KWN:47167
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:OTTMUST00000053690,   OTTMUST00000053691,   OTTMUST00000053693,   OTTMUST00000053694,   OTTMUST00000054564
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv366113,275,571 - 113,277,442 (+)MPROMDB
RGD ID:6839710
Promoter ID:MM_KWN:47168
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   Lung
Transcripts:OTTMUST00000053692
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv366113,283,121 - 113,283,621 (+)MPROMDB
RGD ID:6890624
Promoter ID:EPDNEW_M8763
Type:multiple initiation site
Name:Ogg1_1
Description:Mus musculus 8-oxoguanine DNA-glycosylase 1 , transcript variant1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M8764  EPDNEW_M8765  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm386113,326,998 - 113,327,058EPDNEW
RGD ID:6890626
Promoter ID:EPDNEW_M8764
Type:initiation region
Name:Ogg1_2
Description:Mus musculus 8-oxoguanine DNA-glycosylase 1 , transcript variant1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M8763  EPDNEW_M8765  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm386113,327,256 - 113,327,316EPDNEW
RGD ID:6890640
Promoter ID:EPDNEW_M8765
Type:initiation region
Name:Ogg1_3
Description:Mus musculus 8-oxoguanine DNA-glycosylase 1 , transcript variant1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M8763  EPDNEW_M8764  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm386113,333,318 - 113,333,378EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1097693 AgrOrtholog
Ensembl Genes ENSMUSG00000030271 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000032406 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000144792 UniProtKB/TrEMBL
  ENSMUSP00000144905 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000032406 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000136263 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000204834 UniProtKB/TrEMBL
Gene3D-CATH 1.10.1670.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro DNA_glycosylase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HhH-GPD_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HTH_base_excis_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ogg1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  OGG_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:18294 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1097693 ENTREZGENE
NCBI Gene 18294 ENTREZGENE
Pfam HhH-GPD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  OGG_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB OGG1 RGD
PhenoGen Ogg1 PhenoGen
SMART ENDO3c UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48150 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGRFAMs ogg UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0N4SUR7_MOUSE UniProtKB/TrEMBL
  A0A0N4SV11_MOUSE UniProtKB/TrEMBL
  O08760 ENTREZGENE, UniProtKB/Swiss-Prot
  Q3UIL3 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary O08733 UniProtKB/Swiss-Prot
  O08910 UniProtKB/Swiss-Prot
  O08991 UniProtKB/Swiss-Prot
  O35617 UniProtKB/Swiss-Prot
  O35915 UniProtKB/Swiss-Prot
  Q9QXE8 UniProtKB/Swiss-Prot