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Gene: Ogg1 (8-oxoguanine DNA-glycosylase 1) Mus musculus
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Symbol: Ogg1
Name: 8-oxoguanine DNA-glycosylase 1
Description: Exhibits 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity and microtubule binding activity. Involved in base-excision repair. Localizes to the mitochondrion and nucleus. Human ortholog(s) of this gene implicated in several diseases, including Graves' disease; angiomyolipoma; carcinoma (multiple); endocrine gland cancer (multiple); and eye disease (multiple). Orthologous to human OGG1 (8-oxoguanine DNA glycosylase); PARTICIPATES IN base excision repair pathway; INTERACTS WITH (+)-dexrazoxane; 1,4-benzoquinone; 1H-pyrazole.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Mmh; N-glycosylase/DNA lyase
Orthologs:
Homo sapiens (human) : OGG1 (8-oxoguanine DNA glycosylase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ogg1 (8-oxoguanine DNA glycosylase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ogg1 (8-oxoguanine DNA glycosylase)
Pan paniscus (bonobo/pygmy chimpanzee) : OGG1 (8-oxoguanine DNA glycosylase)
Canis lupus familiaris (dog) : OGG1 (8-oxoguanine DNA glycosylase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ogg1 (8-oxoguanine DNA glycosylase)
Sus scrofa (pig) : OGG1 (8-oxoguanine DNA glycosylase)
Chlorocebus sabaeus (green monkey) : OGG1 (8-oxoguanine DNA glycosylase)
Heterocephalus glaber (naked mole-rat) : Ogg1 (8-oxoguanine DNA glycosylase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl6113,326,972 - 113,335,068 (+)Ensembl
GRCm386113,326,972 - 113,334,877 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv376113,276,970 - 113,284,182 (+)NCBIGRCm37mm9NCBIm37
MGSCv366113,292,788 - 113,299,961 (+)NCBImm8
Celera6115,153,980 - 115,161,188 (+)NCBICelera
Cytogenetic Map6E3NCBI
cM Map652.75NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Ogg1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732766
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-02-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.