Ogg1 (8-oxoguanine DNA-glycosylase 1) - Rat Genome Database

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Gene: Ogg1 (8-oxoguanine DNA-glycosylase 1) Mus musculus
Analyze
Symbol: Ogg1
Name: 8-oxoguanine DNA-glycosylase 1
RGD ID: 732766
MGI Page MGI
Description: Enables 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity and microtubule binding activity. Acts upstream of or within base-excision repair. Located in mitochondrion and nucleus. Is expressed in junctional zone and labyrinthine zone. Human ortholog(s) of this gene implicated in several diseases, including Graves' disease; artery disease (multiple); carcinoma (multiple); eye disease (multiple); and reproductive organ cancer (multiple). Orthologous to human OGG1 (8-oxoguanine DNA glycosylase).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Mmh; N-glycosylase/DNA lyase
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396113,303,959 - 113,311,149 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6113,303,933 - 113,312,029 (+)EnsemblGRCm39 Ensembl
GRCm386113,326,972 - 113,334,877 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6113,326,972 - 113,335,068 (+)EnsemblGRCm38mm10GRCm38
MGSCv376113,276,970 - 113,284,182 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366113,292,788 - 113,299,961 (+)NCBIMGSCv36mm8
Celera6115,153,980 - 115,161,188 (+)NCBICelera
Cytogenetic Map6E3NCBI
cM Map652.75NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Acute Coronary Syndrome  (ISO)
adenocarcinoma  (ISO)
allergic contact dermatitis  (IMP)
angiomyolipoma  (ISO)
Atrioventricular Septal Defect 2  (ISO)
basal cell carcinoma  (ISO)
brain disease  (ISO)
breast cancer  (ISO)
cataract  (ISO)
cholangiocarcinoma  (ISO)
Chromosome Aberrations  (ISO)
clear cell renal cell carcinoma  (ISO)
coronary artery disease  (ISO)
developmental coordination disorder  (ISO)
Discoid Lupus Erythematosus  (ISO)
Endometrial Neoplasms  (ISO)
Experimental Diabetes Mellitus  (IMP,ISO)
Experimental Liver Cirrhosis  (ISO)
Gallbladder Neoplasms  (ISO)
Genetic Predisposition to Disease  (ISO)
gestational diabetes  (ISO)
Graves' disease  (ISO)
head and neck squamous cell carcinoma  (ISO)
Hearing Loss, Noise-Induced  (ISO)
heart disease  (ISO)
hepatitis  (ISO)
human immunodeficiency virus infectious disease  (ISO)
Huntington's disease  (ISO)
Hyperplasia  (ISO)
hypertension  (ISO)
Kidney Reperfusion Injury  (ISO)
long QT syndrome  (ISO)
lung adenocarcinoma  (ISO)
Lung Neoplasms  (ISO)
Lymphatic Metastasis  (ISO)
lymphoma  (ISO)
male infertility  (ISO)
middle cerebral artery infarction  (ISO)
myoclonic-atonic epilepsy  (ISO)
Nerve Degeneration  (ISO)
Neurodevelopmental Disorders  (ISO)
nonpapillary renal cell carcinoma  (ISO)
obesity  (ISO)
ovarian cancer  (ISO)
pancreatic cancer  (ISO)
Parkinson's disease  (ISO)
pre-eclampsia  (ISO)
Premature Birth  (ISO)
Prenatal Exposure Delayed Effects  (ISO)
Prenatal Injuries  (ISO)
primary open angle glaucoma  (ISO)
progressive supranuclear palsy  (ISO)
prostate cancer  (ISO)
Prostatic Neoplasms  (ISO)
pterygium  (ISO)
pulmonary fibrosis  (ISO)
renal cell carcinoma  (ISO)
sarcoma  (IMP)
senile cataract  (ISO)
skin disease  (ISO)
squamous cell carcinoma  (IMP)
status epilepticus  (ISO)
Tongue Neoplasms  (ISO)
toxic shock syndrome  (IMP)
transient cerebral ischemia  (ISO)
transitional cell carcinoma  (ISO)
type 2 diabetes mellitus  (ISO)
Urologic Neoplasms  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-dexrazoxane  (EXP)
(+)-pilocarpine  (ISO)
(S)-nicotine  (ISO)
1,1'-azobis(N,N-dimethylformamide)  (ISO)
1,2-dimethylhydrazine  (ISO)
1,4-benzoquinone  (EXP)
17beta-estradiol  (ISO)
1H-pyrazole  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2,4-dinitrotoluene  (ISO)
2,6-diamino-5-formamido-4-hydroxypyrimidine  (EXP)
3,4-methylenedioxymethamphetamine  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-azacytidine  (EXP)
6-propyl-2-thiouracil  (ISO)
7,12-dimethyltetraphene  (ISO)
7,8-dihydro-8-oxoguanine  (EXP,ISO)
7,9-dihydro-1H-purine-2,6,8(3H)-trione  (EXP)
8-hydroxy-2'-deoxyguanosine  (ISO)
acrolein  (EXP,ISO)
acrylamide  (ISO)
aflatoxin B1  (EXP)
all-trans-retinoic acid  (ISO)
alpha-hexachlorocyclohexane  (ISO)
alpha-pinene  (ISO)
ammonium chloride  (ISO)
aniline  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (EXP)
arsane  (EXP,ISO)
arsenic atom  (EXP,ISO)
arsenite(3-)  (EXP)
arsenous acid  (ISO)
aurintricarboxylic acid  (ISO)
belinostat  (EXP)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
beryllium dichloride  (EXP)
bezafibrate  (EXP)
biphenyl-4-amine  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bleomycin A2  (EXP)
C60 fullerene  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
camphene  (ISO)
carbon atom  (EXP)
carmustine  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
chromium atom  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
crocidolite asbestos  (EXP,ISO)
curcumin  (ISO)
cyclophosphamide  (EXP)
DDT  (ISO)
deoxynivalenol  (ISO)
dexamethasone  (ISO)
Diacetoxyscirpenol  (EXP)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
diethyl maleate  (EXP)
dimethylarsinic acid  (EXP,ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elemental carbon  (EXP)
elemental selenium  (ISO)
entinostat  (ISO)
ethanol  (EXP,ISO)
etoposide  (EXP)
flutamide  (ISO)
folic acid  (ISO)
furan  (ISO)
geraniol  (ISO)
glutathione  (EXP)
glycine betaine  (EXP)
glyphosate  (ISO)
gold atom  (ISO)
gold(0)  (ISO)
hydralazine  (ISO)
hydrazine  (EXP)
hydrazines  (ISO)
hydrogen peroxide  (ISO)
idarubicin  (EXP)
imidacloprid  (ISO)
indometacin  (ISO)
L-ascorbic acid  (ISO)
lead(0)  (EXP,ISO)
lithium atom  (EXP)
lithium hydride  (EXP)
lupeol  (ISO)
mancozeb  (ISO)
manganese atom  (EXP)
manganese(0)  (EXP)
melatonin  (EXP,ISO)
menadione  (ISO)
mercury atom  (EXP)
mercury(0)  (EXP)
metformin  (ISO)
methamphetamine  (EXP,ISO)
methyl methanesulfonate  (ISO)
methyl tert-butyl ether  (ISO)
methylarsonic acid  (ISO)
miconazole  (ISO)
mitomycin C  (EXP)
monocrotophos  (ISO)
myristicin  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (ISO)
nickel atom  (EXP)
nicotine  (ISO)
nimesulide  (ISO)
O-methyleugenol  (ISO)
ochratoxin A  (ISO)
oxaliplatin  (ISO)
oxirane  (ISO)
ozone  (ISO)
paclitaxel  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
parathion-methyl  (EXP)
phenobarbital  (ISO)
pioglitazone  (EXP)
piperonyl butoxide  (EXP)
pirfenidone  (EXP)
potassium bromate  (EXP,ISO)
potassium dichromate  (ISO)
pristane  (EXP)
procyanidin B1  (EXP)
quartz  (ISO)
quercetin  (ISO)
reactive oxygen species  (ISO)
resveratrol  (ISO)
rosmarinic acid  (ISO)
S-adenosyl-L-homocysteine  (EXP)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (EXP)
SB 431542  (ISO)
SCH 23390  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (ISO)
Soman  (ISO)
sterigmatocystin  (ISO)
styrene  (ISO)
tamibarotene  (ISO)
tert-butyl ethyl ether  (ISO)
tetrachloromethane  (EXP)
Thiotepa  (ISO)
Thymidine glycol  (ISO)
titanium dioxide  (EXP,ISO)
topotecan  (ISO)
tributylstannane  (ISO)
trimethylarsine oxide  (ISO)
valproic acid  (ISO)
vincristine  (ISO)
vorinostat  (EXP)
wogonin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
mitochondrion  (HDA,IMP)
nuclear matrix  (ISO,ISS)
nuclear speck  (ISO,ISS)
nucleoplasm  (ISO,ISS)
nucleus  (IBA,IMP,ISO)
protein-containing complex  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Alterations of the DNA repair gene OGG1 in human clear cell carcinomas of the kidney. Audebert M, etal., Cancer Res. 2000 Sep 1;60(17):4740-4.
2. Two functional variations in 5'-UTR of hoGG1 gene associated with the risk of breast cancer in Chinese. Chen X, etal., Breast Cancer Res Treat. 2011 Jun;127(3):795-803. doi: 10.1007/s10549-010-1284-2. Epub 2010 Dec 14.
3. Evidence of alterations in base excision repair of oxidative DNA damage during spontaneous hepatocarcinogenesis in Long Evans Cinnamon rats. Choudhury S, etal., Cancer Res. 2003 Nov 15;63(22):7704-7.
4. DNA repair gene variants in endometrial carcinoma. Cincin ZB, etal., Med Oncol. 2012 Dec;29(4):2949-54. doi: 10.1007/s12032-012-0162-7. Epub 2012 Jan 22.
5. Zhonghua bing li xue za zhi Chinese journal of pathology Cong W, etal., Zhonghua Bing Li Xue Za Zhi. 2001 Jun;30(3):183-7.
6. Multiple genetic alterations involved in the tumorigenesis of human cholangiocarcinoma: a molecular genetic and clinicopathological study. Cong WM, etal., J Cancer Res Clin Oncol. 2001;127(3):187-92.
7. DNA repair gene polymorphisms and prostate cancer risk in South Australia--results of a pilot study. Dhillon VS, etal., Urol Oncol. 2011 Nov-Dec;29(6):641-6. doi: 10.1016/j.urolonc.2009.08.013. Epub 2009 Nov 13.
8. Detecting pathway-based gene-gene and gene-environment interactions in pancreatic cancer. Duell EJ, etal., Cancer Epidemiol Biomarkers Prev. 2008 Jun;17(6):1470-9.
9. Integrated analysis of high-resolution DNA methylation profiles, gene expression, germline genotypes and clinical end points in breast cancer patients. Fleischer T, etal., Int J Cancer. 2014 Jun 1;134(11):2615-25. doi: 10.1002/ijc.28606. Epub 2014 Jan 6.
10. Expression of 8-oxoguanine DNA glycosylase (OGG1) in Parkinson's disease and related neurodegenerative disorders. Fukae J, etal., Acta Neuropathol. 2005 Mar;109(3):256-62. Epub 2004 Nov 17.
11. Polymorphisms of DNA repair genes OGG1 and XPD and the risk of age-related cataract in Egyptians. Gharib AF, etal., Mol Vis. 2014 May 21;20:661-9. eCollection 2014.
12. Association between genetic variants of DNA repair genes and coronary artery disease. Gokkusu C, etal., Genet Test Mol Biomarkers. 2013 Apr;17(4):307-13. doi: 10.1089/gtmb.2012.0383. Epub 2013 Jan 31.
13. Insight into mechanism of oxidative DNA damage in angiomyolipomas from TSC patients. Habib SL Mol Cancer. 2009 Mar 5;8:13. doi: 10.1186/1476-4598-8-13.
14. Genetic polymorphisms in OGG1 and their association with angiomyolipoma, a benign kidney tumor in patients with tuberous sclerosis. Habib SL, etal., Cancer Biol Ther. 2008 Jan;7(1):23-7. Epub 2007 Oct 8.
15. Tuberin haploinsufficiency is associated with the loss of OGG1 in rat kidney tumors. Habib SL, etal., Mol Cancer. 2008 Jan 24;7:10.
16. Ebselen attenuates oxidative DNA damage and enhances its repair activity in the thalamus after focal cortical infarction in hypertensive rats. He M, etal., Brain Res. 2007 Nov 21;1181:83-92. Epub 2007 Sep 8.
17. Human 8-oxoguanine-DNA glycosylase-1 is downregulated in human basal cell carcinoma. Huang XX, etal., Mol Genet Metab. 2012 May;106(1):127-30. doi: 10.1016/j.ymgme.2012.02.017. Epub 2012 Mar 3.
18. Genetic polymorphisms in the base excision repair pathway and cancer risk: a HuGE review. Hung RJ, etal., Am J Epidemiol. 2005 Nov 15;162(10):925-42. Epub 2005 Oct 12.
19. Branched-chain amino acid-enriched nutrients stimulate antioxidant DNA repair in a rat model of liver injury induced by carbon tetrachloride. Ichikawa K, etal., Mol Biol Rep. 2012 Dec;39(12):10803-10. doi: 10.1007/s11033-012-1974-4. Epub 2012 Oct 9.
20. Mitochondrial DNA damage and impaired base excision repair during epileptogenesis. Jarrett SG, etal., Neurobiol Dis. 2008 Apr;30(1):130-8. Epub 2008 Jan 5.
21. Genetic polymorphism of hOGG1 and risk of pterygium in Chinese. Kau HC, etal., Eye (Lond). 2004 Jun;18(6):635-9.
22. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
23. Impact of genetic polymorphisms in base excision repair genes on the risk of breast cancer in a Korean population. Kim KY, etal., Gene. 2013 Dec 15;532(2):192-6. doi: 10.1016/j.gene.2013.09.069. Epub 2013 Sep 25.
24. Immunolocalization of 8-OHdG and OGG1 in pancreatic islets of streptozotocin-induced diabetic rats. Ku YP, etal., Acta Histochem. 2009;111(2):138-44. Epub 2008 Aug 3.
25. Reduced expression of DNA repair genes (XRCC1, XPD, and OGG1) in squamous cell carcinoma of head and neck in North India. Kumar A, etal., Tumour Biol. 2012 Feb;33(1):111-9. doi: 10.1007/s13277-011-0253-7. Epub 2011 Nov 15.
26. 8-Oxoguanine formation induced by chronic UVB exposure makes Ogg1 knockout mice susceptible to skin carcinogenesis. Kunisada M, etal., Cancer Res. 2005 Jul 15;65(14):6006-10.
27. Inducible repair of oxidative DNA lesions in the rat brain after transient focal ischemia and reperfusion. Lan J, etal., J Cereb Blood Flow Metab. 2003 Nov;23(11):1324-39.
28. Effects of base excision repair gene polymorphisms on pancreatic cancer survival. Li D, etal., Int J Cancer. 2007 Apr 15;120(8):1748-54.
29. Oxidative DNA damage and 8-hydroxy-2-deoxyguanosine DNA glycosylase/apurinic lyase in human breast cancer. Li D, etal., Mol Carcinog. 2001 Aug;31(4):214-23.
30. Single nucleotide polymorphisms of DNA base-excision repair genes (APE1, OGG1 and XRCC1) associated with breast cancer risk in a Chinese population. Luo H, etal., Asian Pac J Cancer Prev. 2014;15(3):1133-40.
31. Potential role for 8-oxoguanine DNA glycosylase in regulating inflammation. Mabley JG, etal., FASEB J. 2005 Feb;19(2):290-2. Epub 2004 Dec 1.
32. MGDs mouse GO annotations MGD data from the GO Consortium
33. MGD IEA MGD IEA
34. Synergistic effects of polymorphisms in DNA repair genes and endogenous estrogen exposure on female breast cancer risk. Ming-Shiean H, etal., Ann Surg Oncol. 2010 Mar;17(3):760-71.
35. Protective association exhibited by the single nucleotide polymorphism (SNP) rs1052133 in the gene human 8-oxoguanine DNA glycosylase (hOGG1) with the risk of squamous cell carcinomas of the head & neck (SCCHN) among north Indians. Mitra AK, etal., Indian J Med Res. 2011 Jun;133:605-12.
36. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
37. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
38. DNA glycosylases involved in base excision repair may be associated with cancer risk in BRCA1 and BRCA2 mutation carriers. Osorio A, etal., PLoS Genet. 2014 Apr 3;10(4):e1004256. doi: 10.1371/journal.pgen.1004256. eCollection 2014 Apr.
39. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
40. Mouse MP Annotation Import Pipeline RGD automated import pipeline
41. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
42. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
43. OGG1 polymorphisms and breast cancer risk. Rossner P Jr, etal., Cancer Epidemiol Biomarkers Prev. 2006 Apr;15(4):811-5.
44. A functional Ser326Cys polymorphism in hOGG1 is associated with noise-induced hearing loss in a Chinese population. Shen H, etal., PLoS One. 2014 Mar 5;9(3):e89662. doi: 10.1371/journal.pone.0089662. eCollection 2014.
45. Salivary analysis of oral cancer biomarkers. Shpitzer T, etal., Br J Cancer. 2009 Oct 6;101(7):1194-8. doi: 10.1038/sj.bjc.6605290.
46. Mechanism of oxidative DNA damage in diabetes: tuberin inactivation and downregulation of DNA repair enzyme 8-oxo-7,8-dihydro-2'-deoxyguanosine-DNA glycosylase. Simone S, etal., Diabetes. 2008 Oct;57(10):2626-36. doi: 10.2337/db07-1579. Epub 2008 Jul 3.
47. Polymorphisms of DNA repair genes in endometrial cancer. Sobczuk A, etal., Pathol Oncol Res. 2012 Oct;18(4):1015-20. Epub 2012 Apr 28.
48. Single-nucleotide polymorphisms of DNA repair genes OGG1 and XRCC1: association with gallbladder cancer in North Indian population. Srivastava A, etal., Ann Surg Oncol. 2009 Jun;16(6):1695-703. Epub 2009 Mar 6.
49. Polymorphisms in ERCC2, MSH2, and OGG1 DNA repair genes and gallbladder cancer risk in a population of Northern India. Srivastava K, etal., Cancer. 2010 Jul 1;116(13):3160-9. doi: 10.1002/cncr.25063.
50. Association between DNA damage, DNA repair genes variability and clinical characteristics in breast cancer patients. Synowiec E, etal., Mutat Res. 2008 Dec 15;648(1-2):65-72. doi: 10.1016/j.mrfmmm.2008.09.014. Epub 2008 Oct 10.
51. Association of the 399Arg/Gln XRCC1, the 194 Arg/Trp XRCC1, the 326Ser/Cys OGG1, and the 324Gln/His MUTYH gene polymorphisms with clinical parameters and the risk for development of primary open-angle glaucoma. Szaflik JP, etal., Mutat Res. 2013 Apr 30;753(1):12-22. doi: 10.1016/j.mrgentox.2012.12.019. Epub 2013 Mar 7.
52. The 8-oxoguanine DNA N-glycosylase 1 (hOGG1) Ser326Cys variant affects the susceptibility to Graves' disease. Tanrikulu S, etal., Cell Biochem Funct. 2011 Apr;29(3):244-8. doi: 10.1002/cbf.1742. Epub 2011 Feb 24.
53. Accumulation of 8-oxoguanine in the cellular DNA and the alteration of the OGG1 expression during ischemia-reperfusion injury in the rat kidney. Tsuruya K, etal., DNA Repair (Amst). 2003 Feb 3;2(2):211-29.
54. Islet expression of the DNA repair enzyme 8-oxoguanosine DNA glycosylase (Ogg1) in human type 2 diabetes. Tyrberg B, etal., BMC Endocr Disord. 2002 Apr 25;2(1):2.
55. Disrupted placental vitamin D metabolism and calcium signaling in gestational diabetes and pre-eclampsia patients. Varshney S, etal., Endocrine. 2023 Apr;80(1):191-200. doi: 10.1007/s12020-022-03272-9. Epub 2022 Dec 8.
56. No association between OGG1 Ser326Cys and risk of basal cell carcinoma. Vogel U, etal., Cancer Epidemiol Biomarkers Prev. 2004 Oct;13(10):1680-1.
57. Association of hOGG1 and XPD polymorphisms with urothelial carcinoma in Taiwan. Wang YH, etal., Anticancer Res. 2011 Nov;31(11):3939-44.
58. Genetic polymorphisms in base-excision repair pathway genes and risk of breast cancer. Zhang Y, etal., Cancer Epidemiol Biomarkers Prev. 2006 Feb;15(2):353-8.
59. Genetic polymorphisms in DNA repair genes OGG1, APE1, XRCC1, and XPD and the risk of age-related cataract. Zhang Y, etal., Ophthalmology. 2012 May;119(5):900-6. doi: 10.1016/j.ophtha.2011.11.004. Epub 2012 Feb 4.
60. Susceptibility of XPD and hOGG1 genetic variants to prostate cancer. Zhou C, etal., Biomed Rep. 2013 Jul;1(4):679-683. Epub 2013 May 30.
Additional References at PubMed
PMID:7311623   PMID:8889548   PMID:9088907   PMID:9187114   PMID:9197244   PMID:9207108   PMID:9321410   PMID:9434942   PMID:10098454   PMID:10349636   PMID:10515589   PMID:10557315  
PMID:10570187   PMID:10725358   PMID:10727854   PMID:10775435   PMID:11042159   PMID:11076861   PMID:11369503   PMID:11454679   PMID:11532868   PMID:12200441   PMID:12447686   PMID:12477932  
PMID:12507922   PMID:12615700   PMID:12644468   PMID:12691525   PMID:12759433   PMID:12819227   PMID:12874039   PMID:12904583   PMID:14610273   PMID:14651853   PMID:15126346   PMID:15199168  
PMID:15231648   PMID:15474421   PMID:15721984   PMID:15725623   PMID:15778095   PMID:15782199   PMID:16141072   PMID:16141073   PMID:16221681   PMID:16358418   PMID:16369492   PMID:16478987  
PMID:16494984   PMID:16765995   PMID:16961812   PMID:17003489   PMID:17213818   PMID:17425590   PMID:17441966   PMID:17450122   PMID:17545594   PMID:17675188   PMID:17971305   PMID:17989114  
PMID:18006041   PMID:18258604   PMID:18300266   PMID:18614015   PMID:18768699   PMID:19020090   PMID:19061977   PMID:19389114   PMID:19503746   PMID:19506022   PMID:19594329   PMID:19997493  
PMID:20026424   PMID:20042377   PMID:20067321   PMID:20118626   PMID:20360068   PMID:20485567   PMID:20498273   PMID:20736962   PMID:20956573   PMID:21062970   PMID:21267068   PMID:21322094  
PMID:21505090   PMID:21566259   PMID:21677750   PMID:21715639   PMID:21778470   PMID:21873635   PMID:22001346   PMID:22057269   PMID:22100973   PMID:22209780   PMID:22523232   PMID:22536455  
PMID:22844076   PMID:23127499   PMID:23143307   PMID:23284747   PMID:23355608   PMID:23566953   PMID:23603834   PMID:23612479   PMID:23748360   PMID:23813448   PMID:24121118   PMID:24291244  
PMID:24296244   PMID:24304833   PMID:24429287   PMID:24489103   PMID:24681335   PMID:24732403   PMID:24732879   PMID:24918270   PMID:25113976   PMID:25267977   PMID:25308545   PMID:25311828  
PMID:25358475   PMID:25583175   PMID:25614460   PMID:26210637   PMID:26247199   PMID:26401913   PMID:26496208   PMID:26586787   PMID:26711335   PMID:27251462   PMID:27343030   PMID:27384322  
PMID:27581360   PMID:27596356   PMID:27756845   PMID:27816939   PMID:28127763   PMID:28202616   PMID:28266569   PMID:28727777   PMID:28820464   PMID:28843610   PMID:29101721   PMID:29207315  
PMID:29409673   PMID:29540303   PMID:29795387   PMID:29860357   PMID:30291284   PMID:31284385   PMID:31311771   PMID:31935236   PMID:32209025   PMID:32424276   PMID:32585298   PMID:32808374  
PMID:32929043   PMID:33072095   PMID:33252132   PMID:33503804   PMID:33758207   PMID:34186496   PMID:34575853   PMID:34838904   PMID:35038743   PMID:35708697   PMID:36651270   PMID:37198424  
PMID:37209177   PMID:37373303   PMID:37600772   PMID:37778730   PMID:37977070   PMID:38228016   PMID:38822247   PMID:39235072  


Genomics

Comparative Map Data
Ogg1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396113,303,959 - 113,311,149 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6113,303,933 - 113,312,029 (+)EnsemblGRCm39 Ensembl
GRCm386113,326,972 - 113,334,877 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6113,326,972 - 113,335,068 (+)EnsemblGRCm38mm10GRCm38
MGSCv376113,276,970 - 113,284,182 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366113,292,788 - 113,299,961 (+)NCBIMGSCv36mm8
Celera6115,153,980 - 115,161,188 (+)NCBICelera
Cytogenetic Map6E3NCBI
cM Map652.75NCBI
OGG1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3839,749,952 - 9,783,108 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl39,749,944 - 9,788,219 (+)EnsemblGRCh38hg38GRCh38
GRCh3739,791,636 - 9,808,334 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3639,765,705 - 9,783,342 (+)NCBINCBI36Build 36hg18NCBI36
Build 3439,766,653 - 9,783,311NCBI
Celera39,726,330 - 9,743,054 (+)NCBICelera
Cytogenetic Map3p25.3NCBI
HuRef39,727,975 - 9,744,701 (+)NCBIHuRef
CHM1_139,741,823 - 9,758,548 (+)NCBICHM1_1
T2T-CHM13v2.039,741,907 - 9,758,605 (+)NCBIT2T-CHM13v2.0
Ogg1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84148,030,237 - 148,037,599 (+)NCBIGRCr8
mRatBN7.24146,474,701 - 146,481,959 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4146,474,750 - 146,484,766 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4151,859,153 - 151,865,412 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04147,639,996 - 147,646,255 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04146,261,532 - 146,267,801 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04145,282,828 - 145,289,367 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4145,282,797 - 145,289,326 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04208,580,193 - 208,586,457 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44149,209,745 - 149,219,081 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14149,454,585 - 149,463,922 (+)NCBI
Celera4135,032,266 - 135,038,520 (+)NCBICelera
Cytogenetic Map4q42NCBI
Ogg1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555611,277,365 - 1,282,793 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555611,277,362 - 1,282,949 (+)NCBIChiLan1.0ChiLan1.0
OGG1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v229,761,821 - 9,801,743 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan139,766,593 - 9,806,794 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v039,702,311 - 9,742,283 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.139,940,955 - 9,972,658 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl39,940,955 - 9,947,335 (+)Ensemblpanpan1.1panPan2
OGG1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1208,486,150 - 8,491,448 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl208,480,005 - 8,491,264 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha208,519,224 - 8,524,513 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0208,515,436 - 8,520,730 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl208,515,437 - 8,520,524 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1208,237,911 - 8,243,202 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0208,582,435 - 8,587,727 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0208,556,049 - 8,561,340 (-)NCBIUU_Cfam_GSD_1.0
Ogg1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494215,490,887 - 15,501,164 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366023,413,282 - 3,418,831 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366023,411,106 - 3,418,826 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
OGG1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11366,038,669 - 66,045,478 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21373,102,660 - 73,108,902 (-)NCBISscrofa10.2Sscrofa10.2susScr3
OGG1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12245,757,414 - 45,763,690 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666041120,772,448 - 120,811,082 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ogg1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247314,383,434 - 4,388,196 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247314,383,000 - 4,388,486 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:658
Count of miRNA genes:406
Interacting mature miRNAs:476
Transcripts:ENSMUST00000032406, ENSMUST00000129871, ENSMUST00000136263, ENSMUST00000147945, ENSMUST00000154350
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10043864T2dm4sa_mtype 2 diabetes mellitus 4 in SMXA RI mice (mouse)Not determined683690851146954059Mouse
11252138Clas1_mcarcinogen-induced lung adenoma susceptibility 1 (mouse)6112246918146954059Mouse
1300887Pabr1_mplasma apolipoprotein B (human) regulator 1 (mouse)Not determined6103754405136400690Mouse
1301915Chab3_mcholesterol absorption 3 (mouse)Not determined698908709132916997Mouse
10043923Bhr7_mbronchial hyperresponsiveness 7 (mouse)Not determined698219814132219938Mouse
4141940W6q5_mweight 6 weeks QTL 5 (mouse)Not determined96632912146535124Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46912919136400690Mouse
25314319Histh6_mhistamine hypersensitivity 6 (mouse)648696934125336963Mouse
12792979Fbmd2_mfemoral bone mineral density 2, females only (mouse)675026989115026943Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648696934148351498Mouse
1301509Sluc3_msusceptibility to lung cancer 3 (mouse)Not determined6104480321127019938Mouse
1301962Eila2_methanol induced locomotor activity 2 (mouse)Not determined648703490125333748Mouse
1301518Bbaa5_mB.burgdorferi-associated arthritis 5 (mouse)Not determined698483798145881170Mouse
1301262Gasa3_mgastritis type A susceptibility locus 3 (mouse)Not determined688982366122982564Mouse
11353842Bmiq4_mbody mass index QTL 4 (mouse)692584287146330736Mouse
1302131Bmd8_mbone mineral density 8 (mouse)Not determined699132089133132228Mouse
1301744Hdlq11_mHDL QTL 11 (mouse)Not determined687480321121480516Mouse
10412157Fl1n_mfatty liver 1 in NSY (mouse)Not determined645290993128811995Mouse
11251720Ewc4_methanol withdrawal and consumption 4 (mouse)684099474118099474Mouse
1301687Mnic2_mmacronutrient intake (mouse)Not determined686783787113521563Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139076998Mouse
25440480Moaq2_mmodifier of alien QTL 2 (mouse)63050001117476961Mouse
1357683Igf1sl1_mIGF-1 serum levels 1 (mouse)Not determined652138693116132228Mouse
1357555Tesq2_mtestis weight QTL 2 (mouse)Not determined696632912146535124Mouse
10043891Tilss4_mTNF-induced lethal shock susceptibility 3 (mouse)Not determined6112246918125333748Mouse
1301244Ichs_mimmediate cutaneous hypersensitivity QTL (mouse)Not determined690772571124772807Mouse
4142416Egq11_mearly growth QTL 11 (mouse)Not determined96632912146535124Mouse
1301923Lith6_mlithogenic gene 6 (mouse)Not determined698694477132694676Mouse
10412207Cypr5_mcytokine production 5 (mouse)Not determined6110815180144815323Mouse
1300704Cia3_mcollagen induced arthritis QTL 3 (mouse)Not determined696324286130324483Mouse
13463481Mcvq14_mmean corpuscular volume QTL 14 (mouse)6111142448145142541Mouse
1357793Pnhdlc1_mplasma non-HDL cholesterol 1 (mouse)Not determined6105541783114345810Mouse
1357806Aaj3_manxiety in A/J 3 (mouse)Not determined6104480321136400690Mouse
4141699Ibdq2_minflammatory bowel disease QTL 2 (mouse)Not determined105982366120894102Mouse
13506930Recrq9_mrecombination rate in male meiosis QTL 9 (mouse)673476983134676963Mouse
4141376Dbm1_mdiabetes modifier 1 (mouse)Not determined678606487121092347Mouse
1301292Cfbw2_mcystic fibrosis body weight 2 (mouse)Not determined694981612128981699Mouse
11040599Lmr4b_mleishmaniasis resistance 4b (mouse)696324286130324483Mouse

Markers in Region
AI505105  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386113,334,193 - 113,334,325UniSTSGRCm38
MGSCv376113,284,187 - 113,284,319UniSTSGRCm37
Celera6115,161,193 - 115,161,325UniSTS
Cytogenetic Map6E-F1UniSTS
Cytogenetic Map6E3UniSTS
cM Map648.7UniSTS
Whitehead/MRC_RH61161.76UniSTS
D6Ertd263e  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386113,334,160 - 113,334,384UniSTSGRCm38
MGSCv376113,284,154 - 113,284,378UniSTSGRCm37
Celera6115,161,160 - 115,161,384UniSTS
Cytogenetic Map6E3UniSTS
Cytogenetic Map6E-F1UniSTS
cM Map648.7UniSTS
Ogg1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386113,331,816 - 113,333,367UniSTSGRCm38
MGSCv376113,281,810 - 113,283,361UniSTSGRCm37
Celera6115,158,816 - 115,160,367UniSTS
Cytogenetic Map6E-F1UniSTS
cM Map648.0UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001410130 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001410131 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001410132 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_010957 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_149720 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_176953 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC155287 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF000669 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF003596 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH005779 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ001307 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK008192 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK146870 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK165875 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK167456 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK181469 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK218768 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW048681 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY389525 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY389526 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY389527 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC138733 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC138736 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U88621 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U96711 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y11247 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y13479 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000032406   ⟹   ENSMUSP00000032406
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6113,303,933 - 113,311,149 (+)Ensembl
GRCm38.p6 Ensembl6113,326,972 - 113,334,188 (+)Ensembl
Ensembl Acc Id: ENSMUST00000129871
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6113,303,946 - 113,305,784 (+)Ensembl
GRCm38.p6 Ensembl6113,326,985 - 113,328,823 (+)Ensembl
Ensembl Acc Id: ENSMUST00000136263   ⟹   ENSMUSP00000144792
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6113,303,960 - 113,311,145 (+)Ensembl
GRCm38.p6 Ensembl6113,326,999 - 113,334,184 (+)Ensembl
Ensembl Acc Id: ENSMUST00000147945
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6113,310,279 - 113,312,029 (+)Ensembl
GRCm38.p6 Ensembl6113,333,318 - 113,335,068 (+)Ensembl
Ensembl Acc Id: ENSMUST00000154350
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6113,303,969 - 113,306,291 (+)Ensembl
GRCm38.p6 Ensembl6113,327,008 - 113,329,330 (+)Ensembl
Ensembl Acc Id: ENSMUST00000203721
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6113,304,072 - 113,305,915 (+)Ensembl
GRCm38.p6 Ensembl6113,327,111 - 113,328,954 (+)Ensembl
Ensembl Acc Id: ENSMUST00000204834   ⟹   ENSMUSP00000144905
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6113,303,974 - 113,310,946 (+)Ensembl
GRCm38.p6 Ensembl6113,327,013 - 113,333,985 (+)Ensembl
RefSeq Acc Id: NM_001410130   ⟹   NP_001397059
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396113,303,959 - 113,311,149 (+)NCBI
RefSeq Acc Id: NM_001410131   ⟹   NP_001397060
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396113,303,959 - 113,311,149 (+)NCBI
RefSeq Acc Id: NM_001410132   ⟹   NP_001397061
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396113,303,959 - 113,311,149 (+)NCBI
RefSeq Acc Id: NM_010957   ⟹   NP_035087
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396113,303,959 - 113,311,149 (+)NCBI
GRCm386113,326,976 - 113,334,188 (+)ENTREZGENE
MGSCv376113,276,970 - 113,284,182 (+)RGD
Celera6115,153,980 - 115,161,188 (+)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: NR_149720
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396113,303,959 - 113,311,149 (+)NCBI
GRCm386113,326,976 - 113,334,188 (+)NCBI
Sequence:
RefSeq Acc Id: NR_176953
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396113,303,959 - 113,311,149 (+)NCBI
RefSeq Acc Id: NP_035087   ⟸   NM_010957
- Peptide Label: isoform 1
- UniProtKB: O35915 (UniProtKB/Swiss-Prot),   O35617 (UniProtKB/Swiss-Prot),   O08991 (UniProtKB/Swiss-Prot),   O08910 (UniProtKB/Swiss-Prot),   O08733 (UniProtKB/Swiss-Prot),   Q9QXE8 (UniProtKB/Swiss-Prot),   O08760 (UniProtKB/Swiss-Prot),   Q3UIL3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000032406   ⟸   ENSMUST00000032406
Ensembl Acc Id: ENSMUSP00000144905   ⟸   ENSMUST00000204834
Ensembl Acc Id: ENSMUSP00000144792   ⟸   ENSMUST00000136263
RefSeq Acc Id: NP_001397061   ⟸   NM_001410132
- Peptide Label: isoform 5
RefSeq Acc Id: NP_001397060   ⟸   NM_001410131
- Peptide Label: isoform 4
RefSeq Acc Id: NP_001397059   ⟸   NM_001410130
- Peptide Label: isoform 3
Protein Domains
8-oxoguanine DNA glycosylase N-terminal   HhH-GPD

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O08760-F1-model_v2 AlphaFold O08760 1-345 view protein structure

Promoters
RGD ID:6839752
Promoter ID:MM_KWN:47167
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:OTTMUST00000053690,   OTTMUST00000053691,   OTTMUST00000053693,   OTTMUST00000053694,   OTTMUST00000054564
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv366113,275,571 - 113,277,442 (+)MPROMDB
RGD ID:6839710
Promoter ID:MM_KWN:47168
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   Lung
Transcripts:OTTMUST00000053692
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv366113,283,121 - 113,283,621 (+)MPROMDB
RGD ID:6890624
Promoter ID:EPDNEW_M8763
Type:multiple initiation site
Name:Ogg1_1
Description:Mus musculus 8-oxoguanine DNA-glycosylase 1 , transcript variant1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M8764  EPDNEW_M8765  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm386113,326,998 - 113,327,058EPDNEW
RGD ID:6890626
Promoter ID:EPDNEW_M8764
Type:initiation region
Name:Ogg1_2
Description:Mus musculus 8-oxoguanine DNA-glycosylase 1 , transcript variant1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M8763  EPDNEW_M8765  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm386113,327,256 - 113,327,316EPDNEW
RGD ID:6890640
Promoter ID:EPDNEW_M8765
Type:initiation region
Name:Ogg1_3
Description:Mus musculus 8-oxoguanine DNA-glycosylase 1 , transcript variant1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M8763  EPDNEW_M8764  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm386113,333,318 - 113,333,378EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1097693 AgrOrtholog
Ensembl Genes ENSMUSG00000030271 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000032406 ENTREZGENE
  ENSMUST00000032406.15 UniProtKB/Swiss-Prot
  ENSMUST00000136263 ENTREZGENE
  ENSMUST00000136263.4 UniProtKB/TrEMBL
  ENSMUST00000204834 ENTREZGENE
  ENSMUST00000204834.3 UniProtKB/TrEMBL
Gene3D-CATH 1.10.1670.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.310.40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro DNA_glycosylase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HhH-GPD_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HTH_base_excis_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ogg1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  OGG_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Oxidative_DNA_repair_enzyme UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:18294 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1097693 ENTREZGENE
NCBI Gene 18294 ENTREZGENE
PANTHER 8-OXOGUANINE DNA GLYCOSYLASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  N-GLYCOSYLASE/DNA LYASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam HhH-GPD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  OGG_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB OGG1 RGD
PhenoGen Ogg1 PhenoGen
SMART ENDO3c UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48150 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TATA-box binding protein-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0N4SUR7_MOUSE UniProtKB/TrEMBL
  A0A0N4SV11_MOUSE UniProtKB/TrEMBL
  O08733 ENTREZGENE
  O08760 ENTREZGENE
  O08910 ENTREZGENE
  O08991 ENTREZGENE
  O35617 ENTREZGENE
  O35915 ENTREZGENE
  OGG1_MOUSE UniProtKB/Swiss-Prot
  Q3UIL3 ENTREZGENE, UniProtKB/TrEMBL
  Q9QXE8 ENTREZGENE
UniProt Secondary O08733 UniProtKB/Swiss-Prot
  O08910 UniProtKB/Swiss-Prot
  O08991 UniProtKB/Swiss-Prot
  O35617 UniProtKB/Swiss-Prot
  O35915 UniProtKB/Swiss-Prot
  Q9QXE8 UniProtKB/Swiss-Prot