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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732766
Species: Mus musculus
RGD Object: Gene
Symbol: Ogg1
Name: 8-oxoguanine DNA-glycosylase 1
Acc ID: CHEBI:30621
Term: diarsenic trioxide
Definition: An arsenic oxide in which arsenic and oxygen atoms are present in the ratio 2:3.
Chemical ID: MESH:C006632
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ogg1affects activityISOOGG1 (Homo sapiens)6480464CTDOGG1 protein affects the activity of Arsenic TrioxidePMID:17101720
Ogg1decreases expressionISOOGG1 (Homo sapiens)6480464CTDArsenic Trioxide results in decreased expression of OGG1 mRNAPMID:20458559
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