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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of epidermal cell differentiation
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Accession:GO:0045604 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of epidermal cell differentiation.
Synonyms:related_synonym: regulation of hypodermal cell differentiation


show annotations for term's descendants           Sort by:
regulation of epidermal cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Keap1 Kelch-like ECH-associated protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2681416 (PMID:15087497)		 Ensembl
RGD		 PMID:15087497 GO_REF:0000107 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862 		JBrowse link
G Klf7 KLF transcription factor 7 involved_in ISO (PMID:28916725) RGD PMID:28916725 NCBI chr 9:65,433,683...65,526,372
Ensembl chr 9:65,437,167...65,526,261 		JBrowse link
G Maff MAF bZIP transcription factor F involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:1858732|MGI:96911 (PMID:15087497)		 GO_Central
RGD		 PMID:15087497 GO_REF:0000033 NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851 		JBrowse link
G Mafg MAF bZIP transcription factor G involved_in
acts_upstream_of_or_within		 IBA
ISO
IEA		 GO_REF:0000033
MGI:1858732 (PMID:15087497)
GO_REF:0000118		 GO_Central
RGD
TreeGrafter		 PMID:15087497 GO_REF:0000033 GO_REF:0000118 NCBI chr10:105,903,307...105,911,808
Ensembl chr10:105,903,237...105,912,026 		JBrowse link
negative regulation of epidermal cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dll1 delta like canonical Notch ligand 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3793982|PMID:17960184)		 UniProt
RGD		 PMID:17960184 GO_REF:0000024 MGI:3793982 NCBI chr 1:56,312,062...56,320,177
Ensembl chr 1:56,312,066...56,320,179 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit acts_upstream_of_or_within ISO MGI:2661097 (PMID:19303854) RGD PMID:19303854 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362 		JBrowse link
G Gdf3 growth differentiation factor 3 involved_in ISO (PMID:18823971) RGD PMID:18823971 NCBI chr 4:155,831,572...155,835,953
Ensembl chr 4:155,830,909...155,835,937 		JBrowse link
negative regulation of inner ear auditory receptor cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dll1 delta like canonical Notch ligand 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1932522|MGI:3044907 (PMID:16495313)		 Ensembl
RGD		 PMID:16495313 GO_REF:0000107 NCBI chr 1:56,312,062...56,320,177
Ensembl chr 1:56,312,066...56,320,179 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO MGI:1931521 (PMID:17117437) RGD PMID:17117437 NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:104876|MGI:1341800|MGI:2149672 (PMID:11023859), (PMID:11425898), (PMID:21300049)		 Ensembl
RGD		 PMID:11023859 PMID:11425898 PMID:21300049 GO_REF:0000107 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192 		JBrowse link
G Hes5 hes family bHLH transcription factor 5 acts_upstream_of_or_within ISO MGI:104853|MGI:1341800|MGI:2149674 (PMID:11425898), (PMID:21300049) RGD PMID:11425898 PMID:21300049 NCBI chr 5:165,522,138...165,523,684
Ensembl chr 5:165,522,234...165,523,001 		JBrowse link
G Notch1 notch receptor 1 acts_upstream_of_or_within ISO MGI:3044585 (PMID:25535395) RGD PMID:25535395 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
negative regulation of keratinocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Extl3 exostosin-like glycosyltransferase 3 involved_in ISO (PMID:22727489) RGD PMID:22727489 NCBI chr15:39,294,033...39,384,086
Ensembl chr15:39,293,605...39,338,898 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit acts_upstream_of_or_within ISO MGI:2661097 (PMID:19303854) RGD PMID:19303854 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362 		JBrowse link
G Hoxa7 homeobox A7 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:11435435)
GO_REF:0000107		 RGD
Ensembl		 PMID:11435435 GO_REF:0000107 NCBI chr 4:81,315,730...81,317,629
Ensembl chr 4:81,314,625...81,317,659 		JBrowse link
G Msx2 msh homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1926381 (PMID:19769717)		 Ensembl
RGD		 PMID:19769717 GO_REF:0000107 NCBI chr17:11,097,214...11,102,879
Ensembl chr17:11,097,103...11,102,879 		JBrowse link
G Ovol2 ovo-like zinc finger 2 involved_in ISO (PMID:19700410) RGD PMID:19700410 NCBI chr 3:131,677,391...131,707,123
Ensembl chr 3:131,677,391...131,708,359 		JBrowse link
G Reg3a regenerating islet-derived 3 alpha involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:5488867|PMID:22727489)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:22727489 GO_REF:0000024 GO_REF:0000107 MGI:5488867 NCBI chr 4:110,872,398...110,875,157
Ensembl chr 4:110,872,425...110,875,157 		JBrowse link
G Reg3b regenerating family member 3 beta involved_in ISO (PMID:22727489) RGD PMID:22727489 NCBI chr 4:110,861,775...110,865,015
Ensembl chr 4:110,861,775...110,865,015 		JBrowse link
G Reg3g regenerating family member 3 gamma involved_in ISS
ISO		 GO_REF:0000024
(MGI:5488867|PMID:22727489), (PMID:22727489)		 UniProt
RGD		 PMID:22727489 GO_REF:0000024 MGI:5488867 NCBI chr 4:110,922,805...110,927,803
Ensembl chr 4:110,924,168...110,926,723 		JBrowse link
G Srsf6 serine and arginine rich splicing factor 6 involved_in ISS
ISO		 GO_REF:0000024
(PMID:24440982)		 UniProt
RGD		 PMID:24440982 GO_REF:0000024 NCBI chr 3:151,589,546...151,594,869
Ensembl chr 3:151,589,535...151,594,860 		JBrowse link
G Tp63 tumor protein p63 acts_upstream_of_or_within ISO MGI:5140823 (PMID:22274697) RGD PMID:22274697 NCBI chr11:74,838,858...75,049,764
Ensembl chr11:74,838,859...75,049,398 		JBrowse link
positive regulation of epidermal cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in ISO
IEA
ISS		 (PMID:18823971)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
CAFA		 PMID:18823971 GO_REF:0000024 GO_REF:0000107 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Kdf1 keratinocyte differentiation factor 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5529391|PMID:24075906)		 UniProt
RGD		 PMID:24075906 GO_REF:0000024 MGI:5529391 NCBI chr 5:145,744,753...145,758,150
Ensembl chr 5:145,745,099...145,755,878 		JBrowse link
G Ptch1 patched 1 acts_upstream_of_or_within ISO MGI:1095405 (PMID:24492243) RGD PMID:24492243 NCBI chr17:1,542,705...1,607,730
Ensembl chr17:1,542,877...1,607,333 		JBrowse link
G Ptch2 patched 2 acts_upstream_of_or_within ISO MGI:105373 (PMID:24492243) RGD PMID:24492243 NCBI chr 5:130,571,956...130,592,506
Ensembl chr 5:130,572,312...130,592,405 		JBrowse link
G Sfn stratifin involved_in ISO (MGI:5529391|PMID:24075906) RGD PMID:24075906 MGI:5529391 NCBI chr 5:145,826,722...145,827,994
Ensembl chr 5:145,826,201...145,831,314 		JBrowse link
G Sfrp4 secreted frizzled-related protein 4 involved_in ISO
IEA		 (PMID:18938133)
GO_REF:0000107		 RGD
Ensembl		 PMID:18938133 GO_REF:0000107 NCBI chr17:45,278,867...45,330,806
Ensembl chr17:45,234,097...45,330,736 		JBrowse link
G Sult2b1 sulfotransferase family 2B member 1 involved_in ISO (PMID:28575648) RGD PMID:28575648 NCBI chr 1:96,200,155...96,261,295
Ensembl chr 1:96,200,156...96,261,295 		JBrowse link
positive regulation of inner ear auditory receptor cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atoh1 atonal bHLH transcription factor 1 acts_upstream_of_or_within ISO (PMID:11023859), (PMID:19154718) RGD PMID:11023859 PMID:19154718 NCBI chr 4:93,912,068...93,914,163
Ensembl chr 4:93,912,068...93,914,154 		JBrowse link
G Fgf2 fibroblast growth factor 2 acts_upstream_of_or_within ISO (PMID:12417662) RGD PMID:12417662 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
positive regulation of keratinocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox15b arachidonate 15-lipoxygenase, type B involved_in IEA
ISO		 GO_REF:0000107
(MGI:3784332|PMID:10965849)		 Ensembl
RGD		 PMID:10965849 GO_REF:0000107 MGI:3784332 NCBI chr10:53,892,496...53,901,812
Ensembl chr10:53,892,466...53,901,812 		JBrowse link
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 involved_in ISO
IEA		 (PMID:12496369)
GO_REF:0000107		 RGD
Ensembl		 PMID:12496369 GO_REF:0000107 NCBI chr 7:62,869,340...62,876,242
Ensembl chr 7:62,871,297...62,876,241 		JBrowse link
G Etv4 ETS variant transcription factor 4 involved_in ISO (PMID:31552090) RGD PMID:31552090 NCBI chr10:86,706,749...86,721,974
Ensembl chr10:86,706,749...86,721,974 		JBrowse link
G Foxc1 forkhead box C1 involved_in ISO (PMID:27907090) RGD PMID:27907090 NCBI chr17:32,631,379...32,635,361
Ensembl chr17:32,633,142...32,634,803 		JBrowse link
G Macroh2a1 macroH2A.1 histone involved_in ISO (PMID:23595991) RGD PMID:23595991 NCBI chr17:8,479,331...8,542,071
Ensembl chr17:8,479,372...8,542,072 		JBrowse link
G Macroh2a2 macroH2A.2 histone involved_in ISO (PMID:23595991) RGD PMID:23595991 NCBI chr20:29,678,194...29,727,867
Ensembl chr20:29,678,222...29,727,891 		JBrowse link
G Med1 mediator complex subunit 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:17082781)		 UniProt
RGD		 PMID:17082781 GO_REF:0000024 NCBI chr10:83,145,538...83,189,260
Ensembl chr10:83,145,568...83,189,299 		JBrowse link
G Mir125b1 microRNA 125b-1 acts_upstream_of ISO (PMID:21412257) RGD PMID:21412257 NCBI chr 8:41,952,966...41,953,052
Ensembl chr 8:41,952,966...41,953,052 		JBrowse link
G Mir125b2 microRNA 125b-2 acts_upstream_of ISO (PMID:21412257) RGD PMID:21412257 NCBI chr11:16,245,620...16,245,707 JBrowse link
G Ncoa3 nuclear receptor coactivator 3 involved_in ISO
IEA		 (PMID:17082781), (PMID:17223341)
GO_REF:0000107		 RGD
Ensembl		 PMID:17082781 PMID:17223341 GO_REF:0000107 NCBI chr 3:154,738,566...154,821,395
Ensembl chr 3:154,738,581...154,818,594 		JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 involved_in ISO
ISS		 (PMID:16862176)
GO_REF:0000024		 RGD
HGNC-UCL		 PMID:16862176 GO_REF:0000024 NCBI chr10:78,898,097...78,903,514
Ensembl chr10:78,897,770...78,903,538 		JBrowse link
G Notch1 notch receptor 1 acts_upstream_of_or_within ISO MGI:1330810 (PMID:16618808), (PMID:17079689) RGD PMID:16618808 PMID:17079689 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Numa1 nuclear mitotic apparatus protein 1 involved_in ISO (MGI:5754878|PMID:26765568) RGD PMID:26765568 MGI:5754878 NCBI chr 1:156,297,907...156,372,855
Ensembl chr 1:156,326,259...156,372,855 		JBrowse link
G Ovol2 ovo-like zinc finger 2 acts_upstream_of_or_within ISO (PMID:24735878) RGD PMID:24735878 NCBI chr 3:131,677,391...131,707,123
Ensembl chr 3:131,677,391...131,708,359 		JBrowse link
G Prkch protein kinase C, eta involved_in ISS
ISO		 GO_REF:0000024
(MGI:5306545|PMID:21346190)		 UniProt
RGD		 PMID:21346190 GO_REF:0000024 MGI:5306545 NCBI chr 6:92,292,000...92,490,663
Ensembl chr 6:92,292,000...92,490,654 		JBrowse link
G Trim16 tripartite motif-containing 16 involved_in ISO (PMID:11919186) RGD PMID:11919186 NCBI chr10:47,485,982...47,509,010
Ensembl chr10:47,486,297...47,551,907 		JBrowse link
G Vdr vitamin D receptor involved_in ISO
IEA		 (PMID:17082781)
GO_REF:0000107		 RGD
Ensembl		 PMID:17082781 GO_REF:0000107 NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677 		JBrowse link
regulation of inner ear auditory receptor cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 acts_upstream_of_or_within ISO MGI:104853|MGI:104876 (PMID:21300049) RGD PMID:21300049 NCBI chr 2:93,096,605...93,100,316
Ensembl chr 2:93,095,498...93,100,312 		JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 acts_upstream_of_or_within ISO MGI:104654 (PMID:19154718) RGD PMID:19154718 NCBI chr 1:26,822,131...26,832,218
Ensembl chr 1:26,822,131...26,832,218 		JBrowse link
G Mycl MYCL proto-oncogene, bHLH transcription factor acts_upstream_of_or_within ISO MGI:97357 (PMID:23022312) RGD PMID:23022312 NCBI chr 5:135,274,713...135,281,584
Ensembl chr 5:135,274,748...135,281,582 		JBrowse link
G Mycn MYCN proto-oncogene, bHLH transcription factor involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:96799 (PMID:23022312)		 Ensembl
RGD		 PMID:23022312 GO_REF:0000107 NCBI chr 6:35,717,764...35,723,590
Ensembl chr 6:35,717,764...35,723,590 		JBrowse link
G Notch1 notch receptor 1 acts_upstream_of_or_within ISO MGI:3044585 (PMID:25535395) RGD PMID:25535395 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
regulation of inner ear auditory receptor cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esrp1 epithelial splicing regulatory protein 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5915403|PMID:29107558)		 UniProt
RGD		 PMID:29107558 GO_REF:0000024 MGI:5915403 NCBI chr 5:24,427,611...24,482,157
Ensembl chr 5:24,428,717...24,482,062 		JBrowse link
regulation of keratinocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca12 ATP binding cassette subfamily A member 12 involved_in ISO (PMID:19179616), (PMID:20869849)
(MGI:4462766|PMID:20489143)		 RGD PMID:19179616 PMID:20489143 PMID:20869849 MGI:4462766 NCBI chr 9:72,822,661...72,995,748
Ensembl chr 9:72,823,350...72,996,049 		JBrowse link
G Cd109 CD109 molecule acts_upstream_of_or_within ISO MGI:5443927 (PMID:22490868) RGD PMID:22490868 NCBI chr 8:79,454,480...79,569,195
Ensembl chr 8:79,454,480...79,569,194 		JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 involved_in ISS
IEA
IBA
ISO		 GO_REF:0000024
GO_REF:0000118
GO_REF:0000033
GO_REF:0000107
(MGI:3629275|PMID:16648858)		 UniProt
TreeGrafter
GO_Central
Ensembl
RGD		 PMID:16648858 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 MGI:3629275 NCBI chr 5:161,323,981...161,337,289
Ensembl chr 5:161,323,998...161,337,282 		JBrowse link
G Grhl1 grainyhead-like transcription factor 1 acts_upstream_of_or_within ISO MGI:3778923 (PMID:24586629) RGD PMID:24586629 NCBI chr 6:41,207,325...41,257,516
Ensembl chr 6:41,207,348...41,254,301 		JBrowse link
G Krt36 keratin 36 involved_in ISO (MGI:50776|PMID:1385239) RGD PMID:1385239 MGI:50776 NCBI chr10:85,036,379...85,040,003
Ensembl chr10:85,036,594...85,039,959 		JBrowse link
G Krt84 keratin 84 involved_in ISO (MGI:50776|PMID:1385239) RGD PMID:1385239 MGI:50776 NCBI chr 7:132,649,064...132,656,885
Ensembl chr 7:132,649,061...132,656,874 		JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 involved_in ISO
IEA		 (PMID:19997641)
GO_REF:0000107		 RGD
Ensembl		 PMID:19997641 GO_REF:0000107 NCBI chr18:1,114,532...1,236,345
Ensembl chr18:1,115,905...1,235,571 		JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:19997641)		 Ensembl
RGD		 PMID:19997641 GO_REF:0000107 NCBI chr 6:39,679,116...39,774,033
Ensembl chr 6:39,679,082...39,774,031 		JBrowse link
G Sgpp1 sphingosine-1-phosphate phosphatase 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:5503267|PMID:23637227)		 UniProt
Ensembl
RGD		 PMID:23637227 GO_REF:0000024 GO_REF:0000107 MGI:5503267 NCBI chr 6:94,425,339...94,446,534
Ensembl chr 6:94,425,339...94,446,534 		JBrowse link
G Tnk2 tyrosine kinase, non-receptor, 2 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr11:68,114,725...68,154,254
Ensembl chr11:68,114,726...68,154,009 		JBrowse link
G Zfp36 zinc finger protein 36 involved_in ISS
ISO		 GO_REF:0000024
(PMID:27182009)		 UniProt
RGD		 PMID:27182009 GO_REF:0000024 NCBI chr 1:83,669,084...83,671,564
Ensembl chr 1:83,669,084...83,671,564 		JBrowse link
G Zfp36l1 zinc finger protein 36, C3H type-like 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:27182009)		 UniProt
RGD		 PMID:27182009 GO_REF:0000024 NCBI chr 6:98,930,705...98,935,748
Ensembl chr 6:98,930,718...98,935,748 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    regulation of biological process 13322
      regulation of developmental process 2784
        regulation of epidermis development 68
          regulation of epidermal cell differentiation 61
            negative regulation of epidermal cell differentiation + 16
            positive regulation of epidermal cell differentiation + 26
            regulation of inner ear auditory receptor cell differentiation + 12
            regulation of keratinocyte differentiation + 38
Path 2
Term Annotations click to browse term
  biological_process 20413
    developmental process 7068
      anatomical structure development 6575
        tissue development 2306
          epithelium development 1442
            epithelial cell differentiation 855
              epidermal cell differentiation 261
                regulation of epidermal cell differentiation 61
                  negative regulation of epidermal cell differentiation + 16
                  positive regulation of epidermal cell differentiation + 26
                  regulation of inner ear auditory receptor cell differentiation + 12
                  regulation of keratinocyte differentiation + 38
paths to the root