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ONTOLOGY REPORT - ANNOTATIONS


Term:epidermal cell differentiation
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Accession:GO:0009913 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized features of an epidermal cell, any of the cells making up the epidermis.
Synonyms:related_synonym: hypodermal cell differentiation
 alt_id: GO:0043355



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epidermal cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit acts_upstream_of ISO MGI:2661097 (MGI:3846264|PMID:19303854) RGD PMID:19303854 MGI:3846264 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362
JBrowse link
G Flg filaggrin IMP
NAS
RGD PMID:7688400 PMID:12230510 RGD:1598950, RGD:1598948 NCBI chr 2:178,888,688...178,912,731 JBrowse link
G Gak cyclin G associated kinase acts_upstream_of_or_within ISO MGI:2445832|MGI:5305733 (MGI:5305417|PMID:18434600) RGD PMID:18434600 MGI:5305417 NCBI chr14:1,089,853...1,164,098
Ensembl chr14:1,089,866...1,216,398
JBrowse link
G Gli1 GLI family zinc finger 1 involved_in ISO (PMID:12165851) RGD PMID:12165851 NCBI chr 7:63,156,926...63,169,579
Ensembl chr 7:63,156,926...63,169,251
JBrowse link
G Gli2 GLI family zinc finger 2 involved_in ISO (PMID:12165851) RGD PMID:12165851 NCBI chr13:29,946,809...30,163,901
Ensembl chr13:29,946,809...30,163,574
JBrowse link
G Hdac1 histone deacetylase 1 involved_in ISO UniProtKB:P70288 (MGI:4889029|PMID:21093383) RGD PMID:21093383 MGI:4889029 NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111
JBrowse link
G Hdac2 histone deacetylase 2 involved_in ISO UniProtKB:O09106 (MGI:4889029|PMID:21093383) RGD PMID:21093383 MGI:4889029 NCBI chr20:40,548,250...40,571,609
Ensembl chr20:40,548,250...40,571,609
JBrowse link
G Klf4 Kruppel like factor 4 acts_upstream_of_or_within ISO MGI:2183936 (MGI:1341450|PMID:10431239) RGD PMID:10431239 MGI:1341450 NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602
JBrowse link
G Ovol1 ovo like transcriptional repressor 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:202,855,261...202,868,858
Ensembl chr 1:202,855,265...202,866,831
JBrowse link
G Ovol2 ovo-like zinc finger 2 involved_in IBA
ISO
PMID:21873635
(MGI:5574425|PMID:24735879)
RGD PMID:24735879 PMID:21873635 MGI:5574425, RGD:13792537 NCBI chr 3:131,677,388...131,707,844
Ensembl chr 3:131,677,391...131,708,359
JBrowse link
G Ovol3 ovo-like zinc finger 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:85,484,956...85,488,592
Ensembl chr 1:85,484,956...85,488,592
JBrowse link
G Spink5 serine peptidase inhibitor, Kazal type 5 involved_in ISO (PMID:12915442) RGD PMID:12915442 NCBI chr18:36,264,452...36,333,143
Ensembl chr18:36,264,452...36,332,185
JBrowse link
G Tp63 tumor protein p63 acts_upstream_of_or_within ISO MGI:5882555 (MGI:5824492|PMID:25503409) RGD PMID:25503409 MGI:5824492 NCBI chr11:74,838,858...75,049,764
Ensembl chr11:74,838,859...75,049,398
JBrowse link
auditory receptor cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alg10 ALG10, alpha-1,2-glucosyltransferase acts_upstream_of_or_within ISO MGI:2671810 (MGI:5568671|PMID:24303013) RGD PMID:24303013 MGI:5568671 NCBI chr 7:121,335,042...121,340,308
Ensembl chr 7:121,335,042...121,340,308
JBrowse link
G Clrn1 clarin 1 acts_upstream_of_or_within ISO MGI:3850171 (MGI:3849925|PMID:19414487) RGD PMID:19414487 MGI:3849925 NCBI chr 2:143,084,030...143,130,948
Ensembl chr 2:143,084,030...143,130,948
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 acts_upstream_of_or_within ISO MGI:3574787 (MGI:3527944|PMID:15630379) RGD PMID:15630379 MGI:3527944 NCBI chr16:66,492,445...66,546,731
Ensembl chr16:66,494,042...66,547,350
JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 involved_in ISO
IEA
MGI:2680653 (MGI:5784951|PMID:26084842)
GO_REF:0000107
RGD
Ensembl
PMID:26084842 GO_REF:0000107 MGI:5784951 NCBI chr 1:198,291,711...198,624,683
Ensembl chr 1:198,291,766...198,624,669
JBrowse link
G Lrtomt leucine rich transmembrane and O-methyltransferase domain containing involved_in ISO (MGI:3799635|PMID:18794526) RGD PMID:18794526 MGI:3799635 NCBI chr 1:156,266,655...156,268,704
Ensembl chr 1:156,266,655...156,268,704
JBrowse link
G Pafah1b1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 involved_in ISO (MGI:5477842|PMID:23533177) RGD PMID:23533177 MGI:5477842 NCBI chr10:59,533,042...59,591,808
Ensembl chr10:59,534,117...59,591,808
JBrowse link
G Pdzd7 PDZ domain containing 7 acts_upstream_of_or_within ISO MGI:4433578 (MGI:5565635|PMID:24334608) RGD PMID:24334608 MGI:5565635 NCBI chr 1:243,888,295...243,907,778
Ensembl chr 1:243,888,281...243,906,839
JBrowse link
G Slc4a7 solute carrier family 4 member 7 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:2682641 (MGI:2680888|PMID:12808454)
RGD PMID:12808454 PMID:21873635 MGI:2680888, RGD:13792537 NCBI chr15:10,585,307...10,664,781
Ensembl chr15:10,588,979...10,664,781
JBrowse link
G Tmc1 transmembrane channel-like 1 acts_upstream_of_or_within ISO MGI:5427097 (MGI:5320864|PMID:22105175) RGD PMID:22105175 MGI:5320864 NCBI chr 1:218,275,262...218,445,955
Ensembl chr 1:218,276,417...218,445,955
JBrowse link
auditory receptor cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dll1 delta like canonical Notch ligand 1 involved_in NAS PMID:10878608 UniProt PMID:10878608 RGD:8553270 NCBI chr 1:56,312,062...56,320,177
Ensembl chr 1:56,312,066...56,320,179
JBrowse link
G Jag2 jagged canonical Notch ligand 2 involved_in ISS
ISO
IEA
PMID:10080181
(MGI:1332721|PMID:10080181)
GO_REF:0000107
RGD
Ensembl
PMID:10080181 PMID:10080181 GO_REF:0000107 MGI:1332721, RGD:8553713 NCBI chr 6:131,983,056...132,005,359
Ensembl chr 6:131,983,056...132,005,818
JBrowse link
G Notch1 notch receptor 1 acts_upstream_of_or_within ISO MGI:3044585|MGI:3046196 (MGI:3833041|PMID:19154718) RGD PMID:19154718 MGI:3833041 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region acts_upstream_of_or_within ISO MGI:3046196|MGI:3583755 (MGI:3833041|PMID:19154718) RGD PMID:19154718 MGI:3833041 NCBI chr14:57,338,493...57,523,330
Ensembl chr14:57,338,507...57,523,353
JBrowse link
auditory receptor cell fate determination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atoh1 atonal bHLH transcription factor 1 acts_upstream_of_or_within ISO (MGI:3611666|PMID:16407553) RGD PMID:16407553 MGI:3611666 NCBI chr 4:93,912,068...93,914,163
Ensembl chr 4:93,912,068...93,914,154
JBrowse link
auditory receptor cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atoh1 atonal bHLH transcription factor 1 acts_upstream_of_or_within ISO MGI:2155983 (MGI:1339217|PMID:10364557) RGD PMID:10364557 MGI:1339217 NCBI chr 4:93,912,068...93,914,163
Ensembl chr 4:93,912,068...93,914,154
JBrowse link
auditory receptor cell morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir96 microRNA 96 acts_upstream_of_or_within ISO MGI:4354110 (MGI:4353582|PMID:19363478) RGD PMID:19363478 MGI:4353582 NCBI chr 4:58,788,411...58,788,516
Ensembl chr 4:58,788,411...58,788,516
JBrowse link
G Rac1 Rac family small GTPase 1 acts_upstream_of_or_within ISO MGI:2663662|MGI:2663669 (MGI:4430014|PMID:20016102) RGD PMID:20016102 MGI:4430014 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
JBrowse link
G Scrib scribble planar cell polarity protein acts_upstream_of_or_within ISO MGI:2139764 (MGI:4439427|PMID:20215345) RGD PMID:20215345 MGI:4439427 NCBI chr 7:107,759,343...107,782,364
Ensembl chr 7:107,759,343...107,782,331
JBrowse link
G Sec24b SEC24 homolog B, COPII coat complex component acts_upstream_of_or_within ISO MGI:2145950|MGI:4440621 (MGI:4439427|PMID:20215345) RGD PMID:20215345 MGI:4439427 NCBI chr 2:218,562,670...218,632,753
Ensembl chr 2:218,562,676...218,632,699
JBrowse link
G Slitrk6 SLIT and NTRK-like family, member 6 acts_upstream_of_or_within ISO MGI:4417931 (MGI:4413621|PMID:19936227) RGD PMID:19936227 MGI:4413621 NCBI chr15:87,563,506...87,570,125
Ensembl chr15:87,563,322...87,570,393
JBrowse link
G Wdpcp WD repeat containing planar cell polarity effector acts_upstream_of_or_within ISO MGI:5558098 (MGI:5544506|PMID:24302887) RGD PMID:24302887 MGI:5544506 NCBI chr14:95,645,955...95,977,120
Ensembl chr14:95,646,038...95,977,113
JBrowse link
auditory receptor cell stereocilium organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2b2 ATPase plasma membrane Ca2+ transporting 2 acts_upstream_of_or_within ISO MGI:1856799 (MGI:3709803|PMID:11875276) RGD PMID:11875276 MGI:3709803 NCBI chr 4:146,896,332...147,140,665
Ensembl chr 4:146,896,332...147,140,665
JBrowse link
G Cdh23 cadherin-related 23 acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:1856228|MGI:1856681|MGI:1891428|MGI:2154548|MGI:2154549 (MGI:1929001|PMID:11138008), (MGI:1933915|PMID:11322776), (MGI:3526751|PMID:15537665), (MGI:3625226|PMID:12121736), (MGI:3686545|PMID:17050716), (MGI:5468200|PMID:23217710), (MGI:75953|PMID:7610888), (MGI:81497|PMID:8790740), (MGI:86134|PMID:9039475)
GO_REF:0000107
RGD
Ensembl
PMID:7610888 PMID:8790740 PMID:9039475 PMID:11138008 PMID:11322776 More... GO_REF:0000107 MGI:1929001 MGI:1933915 MGI:3526751 MGI:3625226 MGI:3686545 MGI:5468200 MGI:75953 MGI:81497 MGI:86134 NCBI chr20:28,240,643...28,622,490
Ensembl chr20:28,240,645...28,622,419
JBrowse link
G Clic5 chloride intracellular channel 5 acts_upstream_of_or_within ISO MGI:3663254 (MGI:3663248|PMID:17021174) RGD PMID:17021174 MGI:3663248 NCBI chr 9:16,710,980...16,813,427
Ensembl chr 9:16,710,980...16,813,427
JBrowse link
G Clrn1 clarin 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3850171 (MGI:3849925|PMID:19414487), (MGI:4353469|PMID:19423712)
Ensembl
RGD
PMID:19414487 PMID:19423712 GO_REF:0000107 MGI:3849925 MGI:4353469 NCBI chr 2:143,084,030...143,130,948
Ensembl chr 2:143,084,030...143,130,948
JBrowse link
G Clrn2 clarin 2 involved_in ISO (MGI:6810803|PMID:33496845) RGD PMID:33496845 MGI:6810803 NCBI chr14:65,656,550...65,666,193
Ensembl chr14:65,656,550...65,666,193
JBrowse link
G Grxcr2 glutaredoxin and cysteine rich domain containing 2 acts_upstream_of_or_within ISO MGI:2139535|MGI:6281113|MGI:6281114 (MGI:6278501|PMID:30380417) RGD PMID:30380417 MGI:6278501 NCBI chr18:33,984,689...33,998,094
Ensembl chr18:33,984,689...33,998,094
JBrowse link
G Lhfpl5 LHFPL tetraspan subfamily member 5 acts_upstream_of_or_within ISO MGI:3055797|MGI:3718054 (MGI:3578102|PMID:15905332), (MGI:3759710|PMID:17876667), (MGI:5468200|PMID:23217710) RGD PMID:15905332 PMID:17876667 PMID:23217710 MGI:3578102 MGI:3759710 MGI:5468200 NCBI chr20:6,632,362...6,642,534
Ensembl chr20:6,632,362...6,642,532
JBrowse link
G Myo3a myosin IIIA involved_in ISO MGI:2448580 (MGI:5766107|PMID:26754646) RGD PMID:26754646 MGI:5766107 NCBI chr17:84,554,785...84,604,748
Ensembl chr17:84,543,552...84,759,042
JBrowse link
G Myo3b myosin IIIB involved_in ISO MGI:2183924 (MGI:5766107|PMID:26754646) RGD PMID:26754646 MGI:5766107 NCBI chr 3:54,873,704...55,226,189
Ensembl chr 3:54,820,251...55,227,373
JBrowse link
G Myo7a myosin VIIA acts_upstream_of_or_within ISO MGI:1860092|MGI:2155422 (MGI:2156358|PMID:11753415), (MGI:3625226|PMID:12121736), (MGI:3686545|PMID:17050716) RGD PMID:11753415 PMID:12121736 PMID:17050716 MGI:2156358 MGI:3625226 MGI:3686545 NCBI chr 1:152,342,611...152,414,171
Ensembl chr 1:152,344,448...152,414,157
JBrowse link
G Pcdh15 protocadherin related 15 acts_upstream_of_or_within ISO MGI:1855958|MGI:1856394|MGI:1856396|MGI:1890219|MGI:2151877|MGI:3505691 (MGI:1928787|PMID:10978835), (MGI:3526751|PMID:15537665), (MGI:3619110|PMID:11124469), (MGI:3654702|PMID:16887306), (MGI:5468200|PMID:23217710) RGD PMID:10978835 PMID:11124469 PMID:15537665 PMID:16887306 PMID:23217710 MGI:1928787 MGI:3526751 MGI:3619110 MGI:3654702 MGI:5468200 NCBI chr20:13,997,094...15,496,446
Ensembl chr20:13,963,565...15,494,719
JBrowse link
G Pdzd7 PDZ domain containing 7 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:4433578 (MGI:5565635|PMID:24334608)
RGD PMID:24334608 PMID:21873635 MGI:5565635, RGD:13792537 NCBI chr 1:243,888,295...243,907,778
Ensembl chr 1:243,888,281...243,906,839
JBrowse link
G Pls1 plastin 1 involved_in ISO (MGI:5608770|PMID:25124451) RGD PMID:25124451 MGI:5608770 NCBI chr 8:96,316,703...96,426,592
Ensembl chr 8:96,317,849...96,385,195
JBrowse link
G Rest RE1-silencing transcription factor involved_in ISS
ISO
GO_REF:0000024
(MGI:6193260|PMID:29961578)
UniProt
RGD
PMID:29961578 GO_REF:0000024 MGI:6193260 NCBI chr14:30,859,109...30,879,828
Ensembl chr14:30,862,553...30,894,354
JBrowse link
G Ripor2 RHO family interacting cell polarization regulator 2 involved_in ISO (MGI:5789047|PMID:27269051) RGD PMID:27269051 MGI:5789047 NCBI chr17:40,323,867...40,547,482
Ensembl chr17:40,323,867...40,548,092
JBrowse link
G Scrib scribble planar cell polarity protein acts_upstream_of_or_within ISO MGI:2139764 (MGI:4439427|PMID:20215345) RGD PMID:20215345 MGI:4439427 NCBI chr 7:107,759,343...107,782,364
Ensembl chr 7:107,759,343...107,782,331
JBrowse link
G Sec24b SEC24 homolog B, COPII coat complex component acts_upstream_of_or_within ISO MGI:2145950|MGI:4440621 (MGI:4439427|PMID:20215345) RGD PMID:20215345 MGI:4439427 NCBI chr 2:218,562,670...218,632,753
Ensembl chr 2:218,562,676...218,632,699
JBrowse link
G Slc9a3r1 SLC9A3 regulator 1 acts_upstream_of_or_within ISO MGI:3526430 (MGI:5578076|PMID:24920589) RGD PMID:24920589 MGI:5578076 NCBI chr10:100,403,189...100,420,290
Ensembl chr10:100,403,069...100,420,598
JBrowse link
G Sod1 superoxide dismutase 1 acts_upstream_of_or_within
involved_in
ISO
ISS
MGI:1857872 (MGI:1344578|PMID:10466888), (MGI:3700629|PMID:10464373)
GO_REF:0000024
RGD
UniProt
PMID:10464373 PMID:10466888 GO_REF:0000024 MGI:1344578 MGI:3700629 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Strc stereocilin acts_upstream_of_or_within
involved_in
ISO MGI:3818633 (MGI:3818235|PMID:18849963)
(MGI:5430850|PMID:21165971)
RGD PMID:18849963 PMID:21165971 MGI:3818235 MGI:5430850 NCBI chr 3:108,335,920...108,355,114
Ensembl chr 3:108,335,747...108,354,134
JBrowse link
G Tprn taperin acts_upstream_of_or_within
involved_in
ISO
IBA
MGI:2685697 (MGI:6278501|PMID:30380417)
PMID:21873635
RGD PMID:30380417 PMID:21873635 MGI:6278501, RGD:13792537 NCBI chr 3:8,076,164...8,083,642
Ensembl chr 3:8,075,137...8,083,642
JBrowse link
G Triobp TRIO and F-actin binding protein acts_upstream_of_or_within ISO MGI:4881773 (MGI:4881391|PMID:20510926) RGD PMID:20510926 MGI:4881391 NCBI chr 7:110,505,916...110,569,301
Ensembl chr 7:110,506,248...110,562,474
JBrowse link
G Whrn whirlin involved_in
acts_upstream_of_or_within
IBA
ISO
IEA
PMID:21873635
MGI:4432119 (MGI:5796227|PMID:27117407)
GO_REF:0000107
RGD
Ensembl
PMID:27117407 PMID:21873635 GO_REF:0000107 MGI:5796227, RGD:13792537 NCBI chr 5:76,828,308...76,911,945
Ensembl chr 5:76,828,301...76,912,223
JBrowse link
corneocyte desquamation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca12 ATP binding cassette subfamily A member 12 involved_in ISO (PMID:19179616)
(MGI:6161848|PMID:27551807)
RGD PMID:19179616 PMID:27551807 MGI:6161848 NCBI chr 9:72,822,661...72,995,748
Ensembl chr 9:72,823,350...72,996,049
JBrowse link
G Cdsn corneodesmosin involved_in ISO (PMID:26014679) RGD PMID:26014679 NCBI chr20:3,179,432...3,185,854
Ensembl chr20:3,179,438...3,184,250
JBrowse link
corneocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnase1l2 deoxyribonuclease 1 like 2 acts_upstream_of_or_within ISO MGI:5308556 (MGI:5308183|PMID:21307874) RGD PMID:21307874 MGI:5308183 NCBI chr10:13,471,850...13,473,447
Ensembl chr10:13,471,479...13,473,763
JBrowse link
G Psap prosaposin acts_upstream_of_or_within ISO MGI:1888378|MGI:2183897 (MGI:5607491|PMID:24872419) RGD PMID:24872419 MGI:5607491 NCBI chr20:28,214,229...28,240,501
Ensembl chr20:28,214,271...28,240,498
JBrowse link
cornification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp14 caspase 14 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 7:10,929,759...10,932,591
Ensembl chr 7:10,926,725...10,933,405
JBrowse link
G Cers3 ceramide synthase 3 involved_in ISO (MGI:5303015|PMID:22038835) RGD PMID:22038835 MGI:5303015 NCBI chr 1:120,316,930...120,422,926
Ensembl chr 1:120,318,212...120,422,902
JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 acts_upstream_of_or_within ISO MGI:3039046 (MGI:5466369|PMID:22366455) RGD PMID:22366455 MGI:5466369 NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628
JBrowse link
G Tmem79 transmembrane protein 79 acts_upstream_of_or_within ISO MGI:1856947 (MGI:5519142|PMID:24084074) RGD PMID:24084074 MGI:5519142 NCBI chr 2:173,798,267...173,803,151
Ensembl chr 2:173,798,267...173,803,046
JBrowse link
epidermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Notch1 notch receptor 1 acts_upstream_of_or_within ISO MGI:2178778 (MGI:3042356|PMID:15068794) RGD PMID:15068794 MGI:3042356 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
JBrowse link
G Ptch1 patched 1 acts_upstream_of_or_within ISO MGI:1095405 (MGI:5571965|PMID:24492243) RGD PMID:24492243 MGI:5571965 NCBI chr17:1,542,705...1,607,730
Ensembl chr17:1,542,877...1,607,333
JBrowse link
G Ptch2 patched 2 acts_upstream_of_or_within ISO MGI:105373 (MGI:5571965|PMID:24492243) RGD PMID:24492243 MGI:5571965 NCBI chr 5:130,571,956...130,592,506
Ensembl chr 5:130,572,312...130,592,405
JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region acts_upstream_of_or_within ISO MGI:1926500|MGI:3583755 (MGI:3689772|PMID:17079689) RGD PMID:17079689 MGI:3689772 NCBI chr14:57,338,493...57,523,330
Ensembl chr14:57,338,507...57,523,353
JBrowse link
hair cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dlx3 distal-less homeobox 3 involved_in ISO MGI:3813130|MGI:3813133 (MGI:3812269|PMID:18684741) RGD PMID:18684741 MGI:3812269 NCBI chr10:80,064,489...80,069,891
Ensembl chr10:80,064,489...80,069,872
JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit involved_in
acts_upstream_of_or_within
ISO (PMID:11335038)
MGI:2183949 (MGI:3692802|PMID:17020410)
RGD PMID:11335038 PMID:17020410 MGI:3692802 NCBI chr 1:79,033,342...79,047,102
Ensembl chr 1:79,033,326...79,047,102
JBrowse link
G Ercc3 ERCC excision repair 3, TFIIH core complex helicase subunit involved_in ISO
IBA
(PMID:11335038)
PMID:21873635
RGD PMID:11335038 PMID:21873635 RGD:13792537 NCBI chr18:23,883,613...23,914,326
Ensembl chr18:23,883,580...23,914,329
JBrowse link
G Hes1 hes family bHLH transcription factor 1 IMP RGD PMID:11023859 RGD:9685386 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192
JBrowse link
G Lamc1 laminin subunit gamma 1 involved_in ISO MGI:2683482 (MGI:5828725|PMID:27234308) RGD PMID:27234308 MGI:5828725 NCBI chr13:65,374,372...65,501,492
Ensembl chr13:65,374,372...65,501,492
JBrowse link
G Ush2a usherin acts_upstream_of_or_within
involved_in
ISO (PMID:16301217)
(MGI:5430895|PMID:16301217)
RGD PMID:16301217 MGI:5430895 NCBI chr13:99,837,445...100,503,935
Ensembl chr13:99,837,445...100,503,922
JBrowse link
inner ear auditory receptor cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atoh1 atonal bHLH transcription factor 1 acts_upstream_of_or_within ISO MGI:2155983|MGI:2155984 (MGI:2178088|PMID:11973280), (MGI:3525036|PMID:15543141)
(MGI:3833041|PMID:19154718)
RGD PMID:11973280 PMID:15543141 PMID:19154718 MGI:2178088 MGI:3525036 MGI:3833041 NCBI chr 4:93,912,068...93,914,163
Ensembl chr 4:93,912,068...93,914,154
JBrowse link
G Bmp4 bone morphogenetic protein 4 acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:95524 (MGI:3714221|PMID:17555714)
GO_REF:0000107
RGD
Ensembl
PMID:17555714 GO_REF:0000107 MGI:3714221 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
G Cdh23 cadherin-related 23 acts_upstream_of_or_within ISO MGI:1856228 (MGI:3625226|PMID:12121736) RGD PMID:12121736 MGI:3625226 NCBI chr20:28,240,643...28,622,490
Ensembl chr20:28,240,645...28,622,419
JBrowse link
G Clrn2 clarin 2 acts_upstream_of_or_within ISO MGI:5792002|MGI:6458758 (MGI:6376373|PMID:31448880) RGD PMID:31448880 MGI:6376373 NCBI chr14:65,656,550...65,666,193
Ensembl chr14:65,656,550...65,666,193
JBrowse link
G Cux1 cut-like homeobox 1 acts_upstream_of_or_within ISO MGI:2388352 (MGI:2149924|PMID:11544187) RGD PMID:11544187 MGI:2149924 NCBI chr12:20,107,062...20,425,868
Ensembl chr12:20,107,311...20,425,866
JBrowse link
G Dll1 delta like canonical Notch ligand 1 acts_upstream_of
involved_in
ISO
IEA
MGI:1932522|MGI:3044907 (MGI:3621102|PMID:16495313)
GO_REF:0000107
RGD
Ensembl
PMID:16495313 GO_REF:0000107 MGI:3621102 NCBI chr 1:56,312,062...56,320,177
Ensembl chr 1:56,312,066...56,320,179
JBrowse link
G Fgf2 fibroblast growth factor 2 acts_upstream_of ISO (MGI:2429373|PMID:12417662) RGD PMID:12417662 MGI:2429373 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
JBrowse link
G Fgf20 fibroblast growth factor 20 acts_upstream_of_or_within ISO (MGI:3798124|PMID:18524904) RGD PMID:18524904 MGI:3798124 NCBI chr16:52,030,853...52,037,612
Ensembl chr16:52,010,194...52,038,204
JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO MGI:1931521|MGI:88180 (MGI:3695846|PMID:17117437), (MGI:3714212|PMID:17557302), (MGI:3714221|PMID:17555714)
MGI:1931521 (MGI:3695846|PMID:17117437)
RGD PMID:17117437 PMID:17555714 PMID:17557302 MGI:3695846 MGI:3714212 MGI:3714221 NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341
JBrowse link
G Gfi1 growth factor independent 1 transcriptional repressor acts_upstream_of_or_within ISO MGI:2449921 (MGI:2429425|PMID:12441305) RGD PMID:12441305 MGI:2429425 NCBI chr14:2,040,576...2,056,874
Ensembl chr14:2,042,434...2,051,814
JBrowse link
G Grxcr1 glutaredoxin and cysteine rich domain containing 1 acts_upstream_of_or_within ISO MGI:2681910 (MGI:2680830|PMID:12405956) RGD PMID:12405956 MGI:2680830 NCBI chr14:40,004,169...40,126,571
Ensembl chr14:40,004,169...40,126,571
JBrowse link
G Gsdme gasdermin E acts_upstream_of_or_within ISO MGI:3583715 (MGI:3583372|PMID:16023581) RGD PMID:16023581 MGI:3583372 NCBI chr 4:79,258,799...79,321,129
Ensembl chr 4:79,257,804...79,320,806
JBrowse link
G Hes1 hes family bHLH transcription factor 1 acts_upstream_of
involved_in
ISO
IEA
MGI:104876|MGI:1341800 (MGI:4949990|PMID:21300049)
GO_REF:0000107
RGD
Ensembl
PMID:21300049 GO_REF:0000107 MGI:4949990 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192
JBrowse link
G Hes5 hes family bHLH transcription factor 5 acts_upstream_of ISO MGI:104853|MGI:1341800 (MGI:4949990|PMID:21300049) RGD PMID:21300049 MGI:4949990 NCBI chr 5:165,522,138...165,523,684
Ensembl chr 5:165,522,234...165,523,001
JBrowse link
G Jag1 jagged canonical Notch ligand 1 acts_upstream_of_or_within
involved_in
IMP
ISO
IEA
MGI:1932522|MGI:3623344 (MGI:3621102|PMID:16495313)
GO_REF:0000107
RGD
Ensembl
PMID:16495313 PMID:10887092 GO_REF:0000107 MGI:3621102, RGD:1582345 NCBI chr 3:124,406,794...124,442,220
Ensembl chr 3:124,406,794...124,442,209
JBrowse link
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 acts_upstream_of_or_within ISO MGI:3050114 (MGI:3052624|PMID:15328414), (MGI:3697555|PMID:17074442) RGD PMID:15328414 PMID:17074442 MGI:3052624 MGI:3697555 NCBI chr15:302,078...1,001,198
Ensembl chr15:302,214...1,001,198
JBrowse link
G Mcoln3 mucolipin TRP cation channel 3 acts_upstream_of_or_within ISO MGI:1856230 (MGI:2445676|PMID:12403827) RGD PMID:12403827 MGI:2445676 NCBI chr 2:234,966,010...235,043,047
Ensembl chr 2:234,966,010...235,043,047
JBrowse link
G Myo6 myosin VI involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:1856555 (MGI:1346380|PMID:10525338), (MGI:53523|PMID:5980120), (MGI:77423|PMID:7493015)
RGD PMID:5980120 PMID:7493015 PMID:10525338 PMID:21873635 MGI:1346380 MGI:53523 MGI:77423, RGD:13792537 NCBI chr 8:81,087,157...81,242,022
Ensembl chr 8:81,087,139...81,239,292
JBrowse link
G Myo7a myosin VIIA acts_upstream_of_or_within ISO MGI:1860092|MGI:2155422|MGI:3511858 (MGI:2156358|PMID:11753415), (MGI:3510503|PMID:15389316), (MGI:3625226|PMID:12121736) RGD PMID:11753415 PMID:12121736 PMID:15389316 MGI:2156358 MGI:3510503 MGI:3625226 NCBI chr 1:152,342,611...152,414,171
Ensembl chr 1:152,344,448...152,414,157
JBrowse link
G Pcdh15 protocadherin related 15 acts_upstream_of_or_within ISO MGI:1856394 (MGI:3616414|PMID:16481439) RGD PMID:16481439 MGI:3616414 NCBI chr20:13,997,094...15,496,446
Ensembl chr20:13,963,565...15,494,719
JBrowse link
G Pls3 plastin 3 IEP RGD PMID:12378542 RGD:731234 NCBI chr  X:111,589,193...111,683,908
Ensembl chr  X:111,589,254...111,683,891
JBrowse link
G Pou4f3 POU class 4 homeobox 3 acts_upstream_of_or_within ISO MGI:1857425|MGI:2176270 (MGI:2451279|PMID:12585968), (MGI:80981|PMID:8637595) RGD PMID:8637595 PMID:12585968 MGI:2451279 MGI:80981 NCBI chr18:34,390,205...34,392,797
Ensembl chr18:34,390,205...34,392,797
JBrowse link
G Ush1c USH1 protein network component harmonin involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:2651858|MGI:2651859 (MGI:2675093|PMID:14519688)
RGD PMID:14519688 PMID:21873635 MGI:2675093, RGD:13792537 NCBI chr 1:96,695,303...96,743,671
Ensembl chr 1:96,695,307...96,743,671
JBrowse link
G Ush2a usherin acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:3702040 (MGI:3700725|PMID:17360538)
GO_REF:0000107
RGD
Ensembl
PMID:17360538 GO_REF:0000107 MGI:3700725 NCBI chr13:99,837,445...100,503,935
Ensembl chr13:99,837,445...100,503,922
JBrowse link
keratinization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G 2210017I01Rik RIKEN cDNA 2210017I01 gene involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 Ensembl chr 2:178,182,848...178,183,135 JBrowse link
G AABR07001416.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 7:132,758,366...132,762,047 JBrowse link
G AABR07033579.3 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr11:28,294,843...28,295,058 JBrowse link
G Abca12 ATP binding cassette subfamily A member 12 acts_upstream_of_or_within ISO MGI:3528440|MGI:3809668|MGI:4461044 (MGI:3807143|PMID:18632686), (MGI:3829841|PMID:18957418), (MGI:4460077|PMID:18802465) RGD PMID:18632686 PMID:18802465 PMID:18957418 MGI:3807143 MGI:3829841 MGI:4460077 NCBI chr 9:72,822,661...72,995,748
Ensembl chr 9:72,823,350...72,996,049
JBrowse link
G Cdh3 cadherin 3 involved_in ISO (PMID:22696062) RGD PMID:22696062 NCBI chr19:34,393,596...34,444,084
Ensembl chr19:34,393,727...34,444,084
JBrowse link
G ENSRNOG00000063139 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 Ensembl chr 2:178,356,168...178,356,557 JBrowse link
G ENSRNOG00000066407 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 Ensembl chr 2:178,542,736...178,543,005 JBrowse link
G ENSRNOG00000071041 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr11:28,310,977...28,311,204 JBrowse link
G Il1a interleukin 1 alpha IDA RGD PMID:20385541 RGD:4142790 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Ivl involucrin involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,146,694...178,160,807
Ensembl chr 2:178,147,061...178,149,100
JBrowse link
G Kazn kazrin, periplakin interacting protein involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 5:154,392,793...155,381,567
Ensembl chr 5:154,392,793...154,779,074
JBrowse link
G Kb15 type II keratin Kb15 acts_upstream_of_or_within
involved_in
ISO
IBA
MGI:1333768|MGI:96691 (MGI:3525934|PMID:15601842)
PMID:21873635
RGD PMID:15601842 PMID:21873635 MGI:3525934, RGD:13792537 NCBI chr 7:132,677,994...132,686,634
Ensembl chr 7:132,677,751...132,686,759
JBrowse link
G Kb23 type II keratin 23 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:132,604,180...132,610,869
Ensembl chr 7:132,604,128...132,610,799
JBrowse link
G Krt1 keratin 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:132,976,618...132,981,844
Ensembl chr 7:132,976,620...132,981,844
JBrowse link
G Krt16 keratin 16 involved_in ISO (MGI:5613485|PMID:11029038) RGD PMID:11029038 MGI:5613485 NCBI chr10:85,168,357...85,171,744
Ensembl chr10:85,066,802...85,171,799
JBrowse link
G Krt17 keratin 17 acts_upstream_of_or_within ISO MGI:1100845|MGI:1333768 (MGI:3525934|PMID:15601842) RGD PMID:15601842 MGI:3525934 NCBI chr10:85,178,673...85,183,392
Ensembl chr10:85,178,675...85,183,392
JBrowse link
G Krt2 keratin 2 involved_in ISO
IBA
IEA
(PMID:12598329)
PMID:21873635
GO_REF:0000107
RGD
Ensembl
PMID:12598329 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 7:132,941,275...132,947,963
Ensembl chr 7:132,940,862...132,947,963
JBrowse link
G Krt4 keratin 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:133,046,067...133,052,027
Ensembl chr 7:133,046,515...133,052,019
JBrowse link
G Krt5 keratin 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:132,846,355...132,851,986
Ensembl chr 7:132,846,136...132,851,850
JBrowse link
G Krt7 keratin 7 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:132,528,863...132,545,052
Ensembl chr 7:132,528,895...132,545,052
JBrowse link
G Krt71 keratin 71 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:132,873,532...132,898,975
Ensembl chr 7:132,873,540...132,882,325
JBrowse link
G Krt72 keratin 72 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:132,910,379...132,920,844
Ensembl chr 7:132,910,613...132,920,783
JBrowse link
G Krt73 keratin 73 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:132,927,812...132,936,323
Ensembl chr 7:132,928,256...132,936,280
JBrowse link
G Krt75 keratin 75 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:132,687,101...132,697,360
Ensembl chr 7:132,688,237...132,697,345
JBrowse link
G Krt76 keratin 76 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:133,016,990...133,025,414
Ensembl chr 7:133,016,992...133,025,496
JBrowse link
G Krt77 keratin 77 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:132,989,727...133,002,087
Ensembl chr 7:132,989,717...133,002,101
JBrowse link
G Krt78 keratin 78 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:133,074,193...133,081,536
Ensembl chr 7:133,074,215...133,082,021
JBrowse link
G Krt79 keratin 79 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:133,056,710...133,067,750
Ensembl chr 7:133,056,709...133,067,705
JBrowse link
G Krt8 keratin 8 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
JBrowse link
G Krt80 keratin 80 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:132,464,807...132,485,026
Ensembl chr 7:132,463,218...132,485,508
JBrowse link
G Krt81 keratin 81 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:132,577,112...132,582,238
Ensembl chr 7:132,576,492...132,582,170
JBrowse link
G Krt82 keratin 82 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:132,665,506...132,675,362
Ensembl chr 7:132,665,292...132,675,489
JBrowse link
G Krt83 keratin 83 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:132,547,388...132,554,978
Ensembl chr 7:132,548,141...132,554,978
JBrowse link
G Krt84 keratin 84 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:132,649,064...132,656,885
Ensembl chr 7:132,649,061...132,656,874
JBrowse link
G Krt85 keratin 85 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:132,630,184...132,636,988
Ensembl chr 7:132,630,058...132,637,049
JBrowse link
G Krt86 keratin 86 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:132,591,489...132,598,142
Ensembl chr 7:132,591,545...132,598,021
JBrowse link
G Lce1f late cornified envelope 1F involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,305,786...178,307,372
Ensembl chr 2:178,305,786...178,307,372
JBrowse link
G Lce1g late cornified envelope 1G involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 Ensembl chr 2:178,293,244...178,293,645 JBrowse link
G Lce1l late cornified envelope 1L involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,462,100...178,463,433
Ensembl chr 2:178,462,100...178,463,433
JBrowse link
G Lce1m late cornified envelope 1M involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,637,495...178,638,697
Ensembl chr 2:178,637,495...178,638,697
JBrowse link
G Lce3d late cornified envelope 3D involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,550,187...178,551,541
Ensembl chr 2:178,550,956...178,551,252
JBrowse link
G Lce3e late cornified envelope 3E involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,579,162...178,579,458
Ensembl chr 2:178,579,162...178,579,458
JBrowse link
G Lce3fl1 late cornified envelope 3F-like 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,616,227...178,616,735
Ensembl chr 2:178,616,227...178,616,523
JBrowse link
G LOC100911982 late cornified envelope protein 3C-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,590,377...178,590,673
Ensembl chr 2:178,590,377...178,590,673
JBrowse link
G LOC102549828 late cornified envelope protein 1E-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,367,227...178,367,774
Ensembl chr 2:178,367,382...178,367,774
JBrowse link
G LOC102551936 late cornified envelope protein 1C-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,381,135...178,382,712
Ensembl chr 2:178,381,234...178,381,623
JBrowse link
G LOC102552128 late cornified envelope protein 1C-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,322,769...178,323,158
Ensembl chr 2:178,322,769...178,323,158
JBrowse link
G LOC102552326 late cornified envelope protein 5A-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 Ensembl chr 2:178,275,020...178,275,469 JBrowse link
G LOC103691629 uncharacterized LOC103691629 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,344,421...178,345,204
Ensembl chr 2:178,344,834...178,345,193
JBrowse link
G LOC120100586 late cornified envelope protein 1C-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,232,537...178,234,343
Ensembl chr 2:178,232,733...178,233,155
JBrowse link
G LOC120100587 late cornified envelope protein 1B-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,255,351...178,257,533
Ensembl chr 2:178,256,213...178,257,985
JBrowse link
G LOC120100588 late cornified envelope protein 3D-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,561,990...178,562,532
Ensembl chr 2:178,561,990...178,562,286
JBrowse link
G LOC120100589 late cornified envelope protein 3D-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,598,016...178,598,428
Ensembl chr 2:178,598,016...178,598,312
JBrowse link
G LOC683313 similar to keratin complex 2, basic, gene 6a involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:132,799,608...132,804,045
Ensembl chr 7:132,799,616...132,804,045
JBrowse link
G RGD1305207 similar to RIKEN cDNA 1700011A15 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:132,566,087...132,571,946
Ensembl chr 7:132,561,724...132,571,944
JBrowse link
G Sfn stratifin acts_upstream_of_or_within ISO MGI:1861121 (MGI:55181|PMID:6174530) RGD PMID:6174530 MGI:55181 Ensembl chr 5:145,826,201...145,831,314 JBrowse link
G Sharpin SHANK-associated RH domain interactor acts_upstream_of_or_within ISO MGI:1856699 (MGI:75289|PMID:7792947) RGD PMID:7792947 MGI:75289 NCBI chr 7:108,070,681...108,075,012
Ensembl chr 7:108,070,687...108,074,955
JBrowse link
G Sprr1a small proline-rich protein 1A involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:178,055,096...178,057,012
Ensembl chr 2:178,055,096...178,057,063
JBrowse link
G Tgm1 transglutaminase 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr15:29,191,039...29,206,000
Ensembl chr15:29,191,041...29,204,523
JBrowse link
G Tgm3 transglutaminase 3 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:117,228,661...117,264,078
Ensembl chr 3:117,228,661...117,264,075
JBrowse link
keratinocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl11b BAF chromatin remodeling complex subunit BCL11B acts_upstream_of_or_within ISO MGI:3839576|MGI:3839578 (MGI:3839552|PMID:19092943) RGD PMID:19092943 MGI:3839552 NCBI chr 6:126,834,531...126,927,720
Ensembl chr 6:126,834,531...126,928,224
JBrowse link
G Exph5 exophilin 5 involved_in ISO (PMID:23176819) RGD PMID:23176819 NCBI chr 8:53,698,825...53,775,371
Ensembl chr 8:53,698,852...53,773,169
JBrowse link
G Flnb filamin B acts_upstream_of_or_within ISO (MGI:5516520|PMID:24012369) RGD PMID:24012369 MGI:5516520 NCBI chr15:16,961,999...17,095,059
Ensembl chr15:16,962,003...17,095,006
JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit acts_upstream_of_or_within ISO (MGI:5617064|PMID:25547114) RGD PMID:25547114 MGI:5617064 NCBI chr 6:24,297,898...24,319,157
Ensembl chr 6:24,300,956...24,320,034
JBrowse link
G Ift74 intraflagellar transport 74 acts_upstream_of_or_within ISO (MGI:5013962|PMID:21703454) RGD PMID:21703454 MGI:5013962 NCBI chr 5:109,460,372...109,563,839
Ensembl chr 5:109,474,255...109,563,833
JBrowse link
G Kdf1 keratinocyte differentiation factor 1 acts_upstream_of_or_within ISO MGI:1891831|MGI:5559501 (MGI:5529391|PMID:24075906) RGD PMID:24075906 MGI:5529391 NCBI chr 5:145,744,753...145,758,150
Ensembl chr 5:145,745,099...145,755,878
JBrowse link
G Krt10 keratin 10 acts_upstream_of_or_within ISO MGI:96699 (MGI:5603985|PMID:24751727) RGD PMID:24751727 MGI:5603985 NCBI chr10:84,338,695...84,343,279
Ensembl chr10:84,338,706...84,343,701
JBrowse link
G Krt2 keratin 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:4363845 (MGI:5603985|PMID:24751727)
Ensembl
RGD
PMID:24751727 GO_REF:0000107 MGI:5603985 NCBI chr 7:132,941,275...132,947,963
Ensembl chr 7:132,940,862...132,947,963
JBrowse link
G Palld palladin, cytoskeletal associated protein acts_upstream_of_or_within ISO (MGI:5516520|PMID:24012369) RGD PMID:24012369 MGI:5516520 NCBI chr16:28,228,006...28,621,349
Ensembl chr16:27,981,354...28,621,337
JBrowse link
G Plec plectin involved_in ISO MGI:3721885 (MGI:3721038|PMID:17606998) RGD PMID:17606998 MGI:3721038 NCBI chr 7:107,887,764...107,949,100
Ensembl chr 7:107,887,764...107,945,467
JBrowse link
G Sfn stratifin acts_upstream_of_or_within ISO MGI:1916323 (MGI:5529391|PMID:24075906) RGD PMID:24075906 MGI:5529391 Ensembl chr 5:145,826,201...145,831,314 JBrowse link
G Tfap2a transcription factor AP-2 alpha acts_upstream_of_or_within ISO MGI:106032 (MGI:3826689|PMID:18824566) RGD PMID:18824566 MGI:3826689 NCBI chr17:24,028,716...24,047,507
Ensembl chr17:24,024,432...24,047,507
JBrowse link
G Tfap2c transcription factor AP-2 gamma acts_upstream_of_or_within ISO MGI:104671 (MGI:3826689|PMID:18824566) RGD PMID:18824566 MGI:3826689 NCBI chr 3:161,315,114...161,322,998
Ensembl chr 3:161,315,031...161,322,995
JBrowse link
G Tp63 tumor protein p63 acts_upstream_of_or_within ISO (MGI:3761221|PMID:16601749) RGD PMID:16601749 MGI:3761221 NCBI chr11:74,838,858...75,049,764
Ensembl chr11:74,838,859...75,049,398
JBrowse link
keratinocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca12 ATP binding cassette subfamily A member 12 acts_upstream_of_or_within ISO MGI:4461044 (MGI:4460077|PMID:18802465) RGD PMID:18802465 MGI:4460077 NCBI chr 9:72,822,661...72,995,748
Ensembl chr 9:72,823,350...72,996,049
JBrowse link
G Acer1 alkaline ceramidase 1 involved_in ISO (PMID:16477081) RGD PMID:16477081 NCBI chr 9:1,792,790...1,824,434
Ensembl chr 9:1,793,139...1,824,434
JBrowse link
G Adam9 ADAM metallopeptidase domain 9 involved_in ISO (PMID:17704059) RGD PMID:17704059 NCBI chr16:67,022,538...67,101,647
Ensembl chr16:67,022,655...67,100,917
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 involved_in ISO (PMID:22170488) RGD PMID:22170488 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
JBrowse link
G Anxa1 annexin A1 involved_in IBA
ISO
PMID:21873635
(PMID:10908733)
RGD PMID:10908733 PMID:21873635 RGD:13792537 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 involved_in ISO
ISS
(PMID:17713573)
GO_REF:0000024
RGD
UniProt
PMID:17713573 GO_REF:0000024 NCBI chr16:50,966,404...50,997,827
Ensembl chr16:50,966,229...51,008,233
JBrowse link
G Bcr BCR activator of RhoGEF and GTPase involved_in ISO (PMID:23940119) RGD PMID:23940119 NCBI chr20:13,471,679...13,596,497
Ensembl chr20:13,471,668...13,597,016
JBrowse link
G Casp3 caspase 3 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:2178778 (MGI:3042356|PMID:15068794)
RGD PMID:15068794 PMID:21873635 MGI:3042356, RGD:13792537 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cers3 ceramide synthase 3 involved_in ISO (PMID:23754960) RGD PMID:23754960 NCBI chr 1:120,316,930...120,422,926
Ensembl chr 1:120,318,212...120,422,902
JBrowse link
G Clic4 chloride intracellular channel 4 involved_in IEA
ISO
GO_REF:0000107
(MGI:3723330|PMID:17636002)
(PMID:17636002)
Ensembl
RGD
PMID:17636002 GO_REF:0000107 MGI:3723330 NCBI chr 5:147,456,819...147,513,278
Ensembl chr 5:147,453,712...147,513,452
JBrowse link
G Csta cystatin A involved_in ISO (PMID:10908733) RGD PMID:10908733 NCBI chr11:64,620,483...64,631,488
Ensembl chr11:64,620,483...64,631,488
JBrowse link
G Dsg4 desmoglein 4 acts_upstream_of_or_within ISO MGI:1856929 (MGI:2657041|PMID:12705872) RGD PMID:12705872 MGI:2657041 NCBI chr18:11,720,975...11,756,234
Ensembl chr18:11,720,975...11,756,234
JBrowse link
G Dsp desmoplakin involved_in ISO (PMID:10908733) RGD PMID:10908733 NCBI chr17:26,623,602...26,671,692
Ensembl chr17:26,623,588...26,671,800
JBrowse link
G Epha2 Eph receptor A2 involved_in ISO (PMID:20861311) RGD PMID:20861311 NCBI chr 5:153,605,644...153,634,115
Ensembl chr 5:153,605,644...153,634,117
JBrowse link
G Evpl envoplakin involved_in ISO (PMID:10908733) RGD PMID:10908733 NCBI chr10:101,458,421...101,474,687
Ensembl chr10:101,458,216...101,474,763
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit acts_upstream_of ISO MGI:2661097 (MGI:3846264|PMID:19303854) RGD PMID:19303854 MGI:3846264 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362
JBrowse link
G Foxn1 forkhead box N1 acts_upstream_of_or_within IMP
ISO
(MGI:2176412|PMID:11841548) RGD PMID:11841548 PMID:8790387 MGI:2176412, RGD:1300512 NCBI chr10:63,251,400...63,273,710
Ensembl chr10:63,251,400...63,273,710
JBrowse link
G Gak cyclin G associated kinase acts_upstream_of_or_within ISO MGI:2445832|MGI:5305733 (MGI:5305417|PMID:18434600) RGD PMID:18434600 MGI:5305417 NCBI chr14:1,089,853...1,164,098
Ensembl chr14:1,089,866...1,216,398
JBrowse link
G Intu inturned planar cell polarity protein involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:4441401 (MGI:5545722|PMID:22935613)
Ensembl
RGD
PMID:22935613 GO_REF:0000107 MGI:5545722 NCBI chr 2:123,600,972...123,685,331
Ensembl chr 2:123,609,807...123,682,676
JBrowse link
G Irf6 interferon regulatory factor 6 acts_upstream_of_or_within ISO MGI:3522096|MGI:3693324 (MGI:3691407|PMID:17041601), (MGI:3692825|PMID:17041603) RGD PMID:17041601 PMID:17041603 MGI:3691407 MGI:3692825 NCBI chr13:104,672,179...104,691,386
Ensembl chr13:104,672,179...104,691,386
JBrowse link
G Ivl involucrin involved_in ISO (PMID:10908733) RGD PMID:10908733 NCBI chr 2:178,146,694...178,160,807
Ensembl chr 2:178,147,061...178,149,100
JBrowse link
G Krt10 keratin 10 involved_in
acts_upstream_of_or_within
ISO
IEA
(PMID:22170488)
(MGI:3846264|PMID:19303854)
GO_REF:0000107
RGD
Ensembl
PMID:19303854 PMID:22170488 GO_REF:0000107 MGI:3846264 NCBI chr10:84,338,695...84,343,279
Ensembl chr10:84,338,706...84,343,701
JBrowse link
G Krt14 keratin 14 acts_upstream_of_or_within ISO (MGI:3846264|PMID:19303854) RGD PMID:19303854 MGI:3846264 NCBI chr10:85,137,932...85,141,990
Ensembl chr10:85,066,802...85,171,799
JBrowse link
G Krt16 keratin 16 involved_in ISO (MGI:5613485|PMID:11029038) RGD PMID:11029038 MGI:5613485 NCBI chr10:85,168,357...85,171,744
Ensembl chr10:85,066,802...85,171,799
JBrowse link
G Lats1 large tumor suppressor kinase 1 acts_upstream_of_or_within ISO MGI:103262|MGI:1927144|MGI:1929004 (MGI:3785211|PMID:18369314) RGD PMID:18369314 MGI:3785211 NCBI chr 1:2,160,411...2,193,640
Ensembl chr 1:2,160,411...2,193,640
JBrowse link
G Lats2 large tumor suppressor kinase 2 acts_upstream_of_or_within ISO MGI:103262|MGI:1927144|MGI:1929004 (MGI:3785211|PMID:18369314) RGD PMID:18369314 MGI:3785211 NCBI chr15:31,825,068...31,877,193
Ensembl chr15:31,825,092...31,877,220
JBrowse link
G Loricrin loricrin cornified envelope precursor protein involved_in ISO (PMID:10908733) RGD PMID:10908733 NCBI chr 2:177,558,062...177,559,980
Ensembl chr 2:177,558,252...177,559,807
JBrowse link
G Madcam1 mucosal vascular addressin cell adhesion molecule 1 acts_upstream_of_or_within ISO (MGI:2386364|PMID:12230506) RGD PMID:12230506 MGI:2386364 NCBI chr 7:10,036,301...10,039,703
Ensembl chr 7:10,036,301...10,039,703
JBrowse link
G Mafb MAF bZIP transcription factor B involved_in ISO MGI:3663168 (MGI:5792753|PMID:27208706) RGD PMID:27208706 MGI:5792753 NCBI chr 3:148,998,111...149,000,031
Ensembl chr 3:148,998,122...149,000,031
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:2176412|PMID:11841548)
Ensembl
RGD
PMID:11841548 GO_REF:0000107 MGI:2176412 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
JBrowse link
G Med1 mediator complex subunit 1 involved_in ISO
ISS
(PMID:17223341)
GO_REF:0000024
RGD
UniProt
PMID:17223341 GO_REF:0000024 NCBI chr10:83,145,538...83,189,260
Ensembl chr10:83,145,568...83,189,299
JBrowse link
G Notch1 notch receptor 1 acts_upstream_of_or_within ISO MGI:2178778 (MGI:3042356|PMID:15068794)
MGI:1330810 (MGI:3623698|PMID:16618808)
RGD PMID:15068794 PMID:16618808 MGI:3042356 MGI:3623698 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
JBrowse link
G Opn3 opsin 3 involved_in ISO (PMID:30168605) RGD PMID:30168605 NCBI chr13:87,589,330...87,619,847
Ensembl chr13:87,589,333...87,619,847
JBrowse link
G Pax6 paired box 6 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1856158 (MGI:3584303|PMID:16080917)
Ensembl
RGD
PMID:16080917 GO_REF:0000107 MGI:3584303 NCBI chr 3:92,128,772...92,157,022
Ensembl chr 3:92,135,637...92,157,014
JBrowse link
G Plec plectin involved_in ISO (MGI:5618378|PMID:25447312) RGD PMID:25447312 MGI:5618378 NCBI chr 7:107,887,764...107,949,100
Ensembl chr 7:107,887,764...107,945,467
JBrowse link
G Pnpla1 patatin-like phospholipase domain containing 1 involved_in ISO (MGI:5882269|PMID:27751867), (MGI:5888934|PMID:28248300) RGD PMID:27751867 PMID:28248300 MGI:5882269 MGI:5888934 NCBI chr20:6,918,446...6,951,650
Ensembl chr20:6,917,931...6,952,375
JBrowse link
G Pou2f3 POU class 2 homeobox 3 acts_upstream_of_or_within ISO MGI:101896 (MGI:894946|PMID:9242494) RGD PMID:9242494 MGI:894946 NCBI chr 8:43,495,408...43,577,795
Ensembl chr 8:43,495,527...43,577,795
JBrowse link
G Pou3f1 POU class 3 homeobox 1 acts_upstream_of_or_within ISO MGI:102565 (MGI:894946|PMID:9242494) RGD PMID:9242494 MGI:894946 NCBI chr 5:136,910,391...136,913,371
Ensembl chr 5:136,910,391...136,913,371
JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha involved_in ISS
ISO
GO_REF:0000024
(MGI:4443285|PMID:19626032)
UniProt
RGD
PMID:19626032 GO_REF:0000024 MGI:4443285 NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974
JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region acts_upstream_of_or_within ISO MGI:1926500|MGI:3583755 (MGI:3689772|PMID:17079689) RGD PMID:17079689 MGI:3689772 NCBI chr14:57,338,493...57,523,330
Ensembl chr14:57,338,507...57,523,353
JBrowse link
G Sav1 salvador family WW domain containing protein 1 acts_upstream_of_or_within ISO MGI:103262|MGI:1333883|MGI:1354386|MGI:1929004|MGI:3790763 (MGI:3785211|PMID:18369314) RGD PMID:18369314 MGI:3785211 NCBI chr 6:88,478,536...88,500,121
Ensembl chr 6:88,478,539...88,499,968
JBrowse link
G Scel sciellin involved_in ISO (PMID:14632196) RGD PMID:14632196 NCBI chr15:80,339,661...80,456,546
Ensembl chr15:80,339,951...80,456,372
JBrowse link
G Sfn stratifin acts_upstream_of_or_within ISO MGI:1861121 (MGI:3608244|PMID:16239341) RGD PMID:16239341 MGI:3608244 Ensembl chr 5:145,826,201...145,831,314 JBrowse link
G Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 acts_upstream_of_or_within ISO MGI:2177413|MGI:3605892 (MGI:3604915|PMID:16192310) RGD PMID:16192310 MGI:3604915 NCBI chr 8:20,167,717...20,258,975
Ensembl chr 8:20,167,717...20,258,975
JBrowse link
G Sprr1a small proline-rich protein 1A involved_in ISO (PMID:10908733) RGD PMID:10908733 NCBI chr 2:178,055,096...178,057,012
Ensembl chr 2:178,055,096...178,057,063
JBrowse link
G Sprr1b small proline-rich protein 1B involved_in ISO (PMID:10908733) RGD PMID:10908733 NCBI chr 2:178,009,130...178,009,567
Ensembl chr 2:178,009,130...178,009,567
JBrowse link
G St14 ST14 transmembrane serine protease matriptase involved_in ISO
IBA
(PMID:18843291)
PMID:21873635
RGD PMID:18843291 PMID:21873635 RGD:13792537 NCBI chr 8:29,540,805...29,581,704
Ensembl chr 8:29,540,811...29,581,517
JBrowse link
G Stk4 serine/threonine kinase 4 acts_upstream_of_or_within ISO MGI:103262|MGI:1333883|MGI:1354386|MGI:1927144|MGI:1929004 (MGI:3785211|PMID:18369314) RGD PMID:18369314 MGI:3785211 NCBI chr 3:152,745,958...152,827,747
Ensembl chr 3:152,745,681...152,827,744
JBrowse link
G Tgm1 transglutaminase 1 involved_in ISO (PMID:8824274) RGD PMID:8824274 NCBI chr15:29,191,039...29,206,000
Ensembl chr15:29,191,041...29,204,523
JBrowse link
G Tgm3 transglutaminase 3 involved_in ISO (PMID:12850301) RGD PMID:12850301 NCBI chr 3:117,228,661...117,264,078
Ensembl chr 3:117,228,661...117,264,075
JBrowse link
G Tp63 tumor protein p63 acts_upstream_of_or_within ISO (MGI:3027687|PMID:14729569)
MGI:97363 (MGI:3623698|PMID:16618808)
RGD PMID:14729569 PMID:16618808 MGI:3027687 MGI:3623698 NCBI chr11:74,838,858...75,049,764
Ensembl chr11:74,838,859...75,049,398
JBrowse link
G Tsg101 tumor susceptibility 101 acts_upstream_of_or_within ISO (MGI:2178514|PMID:11943869) RGD PMID:11943869 MGI:2178514 NCBI chr 1:97,412,689...97,442,589
Ensembl chr 1:97,410,848...97,442,554
JBrowse link
G Txnip thioredoxin interacting protein involved_in ISO (PMID:14632196) RGD PMID:14632196 NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
JBrowse link
G Ugcg UDP-glucose ceramide glucosyltransferase involved_in ISS
ISO
GO_REF:0000024
(MGI:5510915|PMID:23748427)
UniProt
RGD
PMID:23748427 GO_REF:0000024 MGI:5510915 NCBI chr 5:74,032,978...74,065,701
Ensembl chr 5:74,032,978...74,065,393
JBrowse link
G Wnt16 Wnt family member 16 involved_in ISO (PMID:17200136) RGD PMID:17200136 NCBI chr 4:50,820,968...50,831,380
Ensembl chr 4:50,820,968...50,831,380
JBrowse link
G Wnt5a Wnt family member 5A involved_in ISO (PMID:19399181) RGD PMID:19399181 NCBI chr16:3,695,667...3,718,234
Ensembl chr16:3,697,032...3,718,234
JBrowse link
G Yap1 Yes1 associated transcriptional regulator acts_upstream_of_or_within ISO MGI:1333883|MGI:1354386|MGI:1927144|MGI:1929004 (MGI:3785211|PMID:18369314) RGD PMID:18369314 MGI:3785211 NCBI chr 8:5,095,705...5,166,808
Ensembl chr 8:5,095,722...5,167,010
JBrowse link
negative regulation of cornification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdsn corneodesmosin involved_in ISO (PMID:26014679) RGD PMID:26014679 NCBI chr20:3,179,432...3,185,854
Ensembl chr20:3,179,438...3,184,250
JBrowse link
negative regulation of epidermal cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dll1 delta like canonical Notch ligand 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:3793982|PMID:17960184)
UniProt
RGD
PMID:17960184 GO_REF:0000024 MGI:3793982 NCBI chr 1:56,312,062...56,320,177
Ensembl chr 1:56,312,066...56,320,179
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit acts_upstream_of_or_within ISO MGI:2661097 (MGI:3846264|PMID:19303854) RGD PMID:19303854 MGI:3846264 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362
JBrowse link
G Gdf3 growth differentiation factor 3 involved_in ISO (PMID:18823971) RGD PMID:18823971 NCBI chr 4:155,831,572...155,835,953
Ensembl chr 4:155,830,909...155,835,937
JBrowse link
negative regulation of inner ear auditory receptor cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dll1 delta like canonical Notch ligand 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1932522|MGI:3044907 (MGI:3621102|PMID:16495313)
Ensembl
RGD
PMID:16495313 GO_REF:0000107 MGI:3621102 NCBI chr 1:56,312,062...56,320,177
Ensembl chr 1:56,312,066...56,320,179
JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO MGI:1931521 (MGI:3695846|PMID:17117437) RGD PMID:17117437 MGI:3695846 NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341
JBrowse link
G Hes1 hes family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:104876|MGI:1341800|MGI:2149672 (MGI:1889857|PMID:11023859), (MGI:2136156|PMID:11425898), (MGI:4949990|PMID:21300049)
Ensembl
RGD
PMID:11023859 PMID:11425898 PMID:21300049 GO_REF:0000107 MGI:1889857 MGI:2136156 MGI:4949990 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192
JBrowse link
G Hes5 hes family bHLH transcription factor 5 acts_upstream_of_or_within ISO MGI:104853|MGI:1341800|MGI:2149674 (MGI:2136156|PMID:11425898), (MGI:4949990|PMID:21300049) RGD PMID:11425898 PMID:21300049 MGI:2136156 MGI:4949990 NCBI chr 5:165,522,138...165,523,684
Ensembl chr 5:165,522,234...165,523,001
JBrowse link
G Notch1 notch receptor 1 acts_upstream_of_or_within ISO MGI:3044585 (MGI:5617067|PMID:25535395) RGD PMID:25535395 MGI:5617067 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
JBrowse link
negative regulation of keratinocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit acts_upstream_of_or_within ISO MGI:2661097 (MGI:3846264|PMID:19303854) RGD PMID:19303854 MGI:3846264 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362
JBrowse link
G Grhl2 grainyhead-like transcription factor 2 involved_in ISO (PMID:23254293) RGD PMID:23254293 NCBI chr 7:68,400,287...68,530,269
Ensembl chr 7:68,400,477...68,530,258
JBrowse link
G Hoxa7 homeobox A7 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:11435435)
GO_REF:0000107
RGD
Ensembl
PMID:11435435 GO_REF:0000107 NCBI chr 4:81,315,730...81,317,629
Ensembl chr 4:81,314,625...81,317,659
JBrowse link
G Msx2 msh homeobox 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1926381 (MGI:4868690|PMID:19769717)
Ensembl
RGD
PMID:19769717 GO_REF:0000107 MGI:4868690 NCBI chr17:11,097,214...11,102,879
Ensembl chr17:11,097,103...11,102,879
JBrowse link
G Ovol2 ovo-like zinc finger 2 involved_in ISO (PMID:19700410) RGD PMID:19700410 NCBI chr 3:131,677,388...131,707,844
Ensembl chr 3:131,677,391...131,708,359
JBrowse link
G Reg3a regenerating islet-derived 3 alpha involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:5488867|PMID:22727489)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:22727489 GO_REF:0000024 GO_REF:0000107 MGI:5488867 NCBI chr 4:110,872,398...110,875,157
Ensembl chr 4:110,872,425...110,875,157
JBrowse link
G Reg3g regenerating family member 3 gamma involved_in ISS
ISO
GO_REF:0000024
(MGI:5488867|PMID:22727489)
UniProt
RGD
PMID:22727489 GO_REF:0000024 MGI:5488867 NCBI chr 4:110,922,805...110,927,803
Ensembl chr 4:110,924,168...110,926,723
JBrowse link
G Srsf6 serine and arginine rich splicing factor 6 involved_in ISS
ISO
GO_REF:0000024
(PMID:24440982)
UniProt
RGD
PMID:24440982 GO_REF:0000024 NCBI chr 3:151,589,546...151,594,869
Ensembl chr 3:151,589,535...151,594,860
JBrowse link
G Tp63 tumor protein p63 acts_upstream_of_or_within ISO MGI:5140823 (MGI:5310685|PMID:22274697)
MGI:97363 (MGI:3623698|PMID:16618808)
RGD PMID:16618808 PMID:22274697 MGI:3623698 MGI:5310685 NCBI chr11:74,838,858...75,049,764
Ensembl chr11:74,838,859...75,049,398
JBrowse link
neuromast hair cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc44a4 solute carrier family 44, member 4 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr20:3,903,099...3,919,215
Ensembl chr20:3,903,099...3,919,215
JBrowse link
positive regulation of epidermal cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in ISO
ISS
IEA
(PMID:18823971)
GO_REF:0000024
GO_REF:0000107
RGD
CAFA
Ensembl
PMID:18823971 GO_REF:0000024 GO_REF:0000107 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
G Kdf1 keratinocyte differentiation factor 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:5529391|PMID:24075906)
UniProt
RGD
PMID:24075906 GO_REF:0000024 MGI:5529391 NCBI chr 5:145,744,753...145,758,150
Ensembl chr 5:145,745,099...145,755,878
JBrowse link
G Ptch1 patched 1 acts_upstream_of_or_within ISO MGI:1095405 (MGI:5571965|PMID:24492243) RGD PMID:24492243 MGI:5571965 NCBI chr17:1,542,705...1,607,730
Ensembl chr17:1,542,877...1,607,333
JBrowse link
G Ptch2 patched 2 acts_upstream_of_or_within ISO MGI:105373 (MGI:5571965|PMID:24492243) RGD PMID:24492243 MGI:5571965 NCBI chr 5:130,571,956...130,592,506
Ensembl chr 5:130,572,312...130,592,405
JBrowse link
G Sfn stratifin involved_in ISO (MGI:5529391|PMID:24075906) RGD PMID:24075906 MGI:5529391 Ensembl chr 5:145,826,201...145,831,314 JBrowse link
G Sfrp4 secreted frizzled-related protein 4 involved_in ISO
IEA
(PMID:18938133)
GO_REF:0000107
RGD
Ensembl
PMID:18938133 GO_REF:0000107 NCBI chr17:45,278,867...45,330,806
Ensembl chr17:45,234,097...45,330,736
JBrowse link
G Sult2b1 sulfotransferase family 2B member 1 involved_in ISO (PMID:28575648) RGD PMID:28575648 NCBI chr 1:96,200,155...96,261,295
Ensembl chr 1:96,200,156...96,261,295
JBrowse link
positive regulation of inner ear auditory receptor cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atoh1 atonal bHLH transcription factor 1 acts_upstream_of_or_within ISO (MGI:1889857|PMID:11023859), (MGI:3833041|PMID:19154718) RGD PMID:11023859 PMID:19154718 MGI:1889857 MGI:3833041 NCBI chr 4:93,912,068...93,914,163
Ensembl chr 4:93,912,068...93,914,154
JBrowse link
G Fgf2 fibroblast growth factor 2 acts_upstream_of_or_within ISO (MGI:2429373|PMID:12417662) RGD PMID:12417662 MGI:2429373 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
JBrowse link
positive regulation of keratinocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox15b arachidonate 15-lipoxygenase, type B involved_in IEA
ISO
GO_REF:0000107
(MGI:3784332|PMID:10965849)
Ensembl
RGD
PMID:10965849 GO_REF:0000107 MGI:3784332 NCBI chr10:53,892,496...53,901,812
Ensembl chr10:53,892,466...53,901,812
JBrowse link
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 involved_in ISO
IEA
(PMID:12496369)
GO_REF:0000107
RGD
Ensembl
PMID:12496369 GO_REF:0000107 NCBI chr 7:62,869,340...62,876,242
Ensembl chr 7:62,871,297...62,876,241
JBrowse link
G Etv4 ETS variant transcription factor 4 involved_in ISO (PMID:31552090) RGD PMID:31552090 NCBI chr10:86,706,749...86,721,974
Ensembl chr10:86,706,749...86,721,974
JBrowse link
G Foxc1 forkhead box C1 involved_in ISO (PMID:27907090) RGD PMID:27907090 NCBI chr17:32,631,379...32,635,361
Ensembl chr17:32,633,142...32,634,803
JBrowse link
G Macroh2a1 macroH2A.1 histone involved_in ISO (PMID:23595991) RGD PMID:23595991 NCBI chr17:8,479,331...8,542,071
Ensembl chr17:8,479,372...8,542,072
JBrowse link
G Macroh2a2 macroH2A.2 histone involved_in ISO (PMID:23595991) RGD PMID:23595991 NCBI chr20:29,678,194...29,727,867
Ensembl chr20:29,678,222...29,727,891
JBrowse link
G Med1 mediator complex subunit 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:17082781)
UniProt
RGD
PMID:17082781 GO_REF:0000024 NCBI chr10:83,145,538...83,189,260
Ensembl chr10:83,145,568...83,189,299
JBrowse link
G Mir125b1 microRNA 125b-1 acts_upstream_of ISO (PMID:21412257) RGD PMID:21412257 NCBI chr 8:41,952,966...41,953,052
Ensembl chr 8:41,952,966...41,953,052
JBrowse link
G Mir125b2 microRNA 125b-2 acts_upstream_of ISO (PMID:21412257) RGD PMID:21412257 NCBI chr11:16,245,620...16,245,707 JBrowse link
G Ncoa3 nuclear receptor coactivator 3 involved_in ISO
IEA
(PMID:17082781), (PMID:17223341)
GO_REF:0000107
RGD
Ensembl
PMID:17082781 PMID:17223341 GO_REF:0000107 NCBI chr 3:154,738,566...154,821,395
Ensembl chr 3:154,738,581...154,818,594
JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 involved_in ISO
ISS
(PMID:16862176)
GO_REF:0000024
RGD
HGNC-UCL
PMID:16862176 GO_REF:0000024 NCBI chr10:78,898,097...78,903,600
Ensembl chr10:78,897,770...78,903,538
JBrowse link
G Notch1 notch receptor 1 acts_upstream_of_or_within ISO MGI:1330810 (MGI:3623698|PMID:16618808), (MGI:3689772|PMID:17079689) RGD PMID:16618808 PMID:17079689 MGI:3623698 MGI:3689772 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
JBrowse link
G Numa1 nuclear mitotic apparatus protein 1 involved_in ISO (MGI:5754878|PMID:26765568) RGD PMID:26765568 MGI:5754878 NCBI chr 1:156,297,907...156,372,855
Ensembl chr 1:156,326,259...156,372,855
JBrowse link
G Ovol2 ovo-like zinc finger 2 acts_upstream_of_or_within ISO (MGI:5584327|PMID:24735878) RGD PMID:24735878 MGI:5584327 NCBI chr 3:131,677,388...131,707,844
Ensembl chr 3:131,677,391...131,708,359
JBrowse link
G Prkch protein kinase C, eta involved_in ISS
ISO
GO_REF:0000024
(MGI:5306545|PMID:21346190)
UniProt
RGD
PMID:21346190 GO_REF:0000024 MGI:5306545 NCBI chr 6:92,292,000...92,490,663
Ensembl chr 6:92,292,000...92,490,654
JBrowse link
G Trim16 tripartite motif-containing 16 involved_in ISO (PMID:11919186) RGD PMID:11919186 NCBI chr10:47,485,982...47,509,010
Ensembl chr10:47,486,297...47,551,907
JBrowse link
G Vdr vitamin D receptor involved_in ISO
IEA
(PMID:17082781)
GO_REF:0000107
RGD
Ensembl
PMID:17082781 GO_REF:0000107 NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677
JBrowse link
posterior lateral line neuromast hair cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tmem132e transmembrane protein 132E involved_in ISO UniProtKB:L7VG99 (PMID:25331638) RGD PMID:25331638 NCBI chr10:67,329,347...67,386,790
Ensembl chr10:67,330,751...67,386,789
JBrowse link
regulation of epidermal cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Keap1 Kelch-like ECH-associated protein 1 acts_upstream_of_or_within ISO MGI:2681416 (MGI:3040741|PMID:15087497) RGD PMID:15087497 MGI:3040741 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
JBrowse link
G Klf7 Kruppel like factor 7 involved_in ISO (PMID:28916725) RGD PMID:28916725 NCBI chr 9:65,437,535...65,484,720
NCBI chr 9:65,433,683...65,526,372
Ensembl chr 9:65,437,167...65,526,261
JBrowse link
G LOC120094803 Kruppel like factor 7 involved_in ISO (PMID:28916725) RGD PMID:28916725 NCBI chr 9:65,433,683...65,526,372
Ensembl chr 9:65,437,167...65,526,261
JBrowse link
G Maff MAF bZIP transcription factor F involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:1858732|MGI:96911 (MGI:3040741|PMID:15087497)
RGD PMID:15087497 PMID:21873635 MGI:3040741, RGD:13792537 NCBI chr 7:110,912,499...110,923,851
Ensembl chr 7:110,912,499...110,923,851
JBrowse link
G Mafg MAF bZIP transcription factor G involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:1858732 (MGI:3040741|PMID:15087497)
RGD PMID:15087497 PMID:21873635 MGI:3040741, RGD:13792537 NCBI chr10:105,903,307...105,911,845
Ensembl chr10:105,903,237...105,912,026
JBrowse link
regulation of inner ear auditory receptor cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 acts_upstream_of_or_within ISO MGI:104853|MGI:104876 (MGI:4949990|PMID:21300049) RGD PMID:21300049 MGI:4949990 NCBI chr 2:93,096,706...93,100,316
Ensembl chr 2:93,095,498...93,100,312
JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 acts_upstream_of_or_within ISO MGI:104654 (MGI:3833041|PMID:19154718) RGD PMID:19154718 MGI:3833041 NCBI chr 1:26,822,131...26,832,218
Ensembl chr 1:26,822,131...26,832,218
JBrowse link
G Mycl MYCL proto-oncogene, bHLH transcription factor acts_upstream_of_or_within ISO MGI:97357 (MGI:5468771|PMID:23022312) RGD PMID:23022312 MGI:5468771 NCBI chr 5:135,274,713...135,281,584
Ensembl chr 5:135,274,748...135,281,582
JBrowse link
G Mycn MYCN proto-oncogene, bHLH transcription factor acts_upstream_of_or_within ISO MGI:96799 (MGI:5468771|PMID:23022312) RGD PMID:23022312 MGI:5468771 NCBI chr 6:35,717,764...35,723,590
Ensembl chr 6:35,717,764...35,723,590
JBrowse link
G Notch1 notch receptor 1 acts_upstream_of_or_within ISO MGI:3044585 (MGI:5617067|PMID:25535395) RGD PMID:25535395 MGI:5617067 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
JBrowse link
regulation of inner ear auditory receptor cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esrp1 epithelial splicing regulatory protein 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:5915403|PMID:29107558)
UniProt
RGD
PMID:29107558 GO_REF:0000024 MGI:5915403 NCBI chr 5:24,427,611...24,482,157
Ensembl chr 5:24,428,717...24,482,062
JBrowse link
regulation of keratinocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca12 ATP binding cassette subfamily A member 12 involved_in ISO (PMID:19179616), (PMID:20869849)
(MGI:4462766|PMID:20489143)
RGD PMID:19179616 PMID:20489143 PMID:20869849 MGI:4462766 NCBI chr 9:72,822,661...72,995,748
Ensembl chr 9:72,823,350...72,996,049
JBrowse link
G Cd109 CD109 molecule acts_upstream_of_or_within ISO MGI:5443927 (MGI:5441431|PMID:22490868) RGD PMID:22490868 MGI:5441431 NCBI chr 8:79,454,480...79,569,195
Ensembl chr 8:79,454,480...79,569,194
JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 involved_in IBA
ISO
ISS
PMID:21873635
(MGI:3629275|PMID:16648858)
GO_REF:0000024
RGD
UniProt
PMID:16648858 PMID:21873635 GO_REF:0000024 MGI:3629275, RGD:13792537 NCBI chr 5:161,323,981...161,337,289
Ensembl chr 5:161,323,998...161,337,282
JBrowse link
G Grhl1 grainyhead-like transcription factor 1 acts_upstream_of_or_within ISO MGI:3778923 (MGI:5585711|PMID:24586629) RGD PMID:24586629 MGI:5585711 NCBI chr 6:41,207,325...41,257,516
Ensembl chr 6:41,207,348...41,254,301
JBrowse link
G Krt36 keratin 36 involved_in ISO (MGI:50776|PMID:1385239) RGD PMID:1385239 MGI:50776 NCBI chr10:85,036,594...85,039,959
Ensembl chr10:85,036,594...85,039,959
JBrowse link
G Krt84 keratin 84 involved_in ISO (MGI:50776|PMID:1385239) RGD PMID:1385239 MGI:50776 NCBI chr 7:132,649,064...132,656,885
Ensembl chr 7:132,649,061...132,656,874
JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 involved_in ISO
IEA
(PMID:19997641)
GO_REF:0000107
RGD
Ensembl
PMID:19997641 GO_REF:0000107 NCBI chr18:1,114,532...1,236,345
Ensembl chr18:1,115,905...1,235,571
JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:19997641)
Ensembl
RGD
PMID:19997641 GO_REF:0000107 NCBI chr 6:39,679,116...39,774,033
Ensembl chr 6:39,679,082...39,774,031
JBrowse link
G Sgpp1 sphingosine-1-phosphate phosphatase 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(MGI:5503267|PMID:23637227)
UniProt
Ensembl
RGD
PMID:23637227 GO_REF:0000024 GO_REF:0000107 MGI:5503267 NCBI chr 6:94,425,339...94,446,534
Ensembl chr 6:94,425,339...94,446,534
JBrowse link
G Zfp36 zinc finger protein 36 involved_in ISS
ISO
GO_REF:0000024
(PMID:27182009)
UniProt
RGD
PMID:27182009 GO_REF:0000024 NCBI chr 1:83,669,084...83,671,564
Ensembl chr 1:83,669,084...83,671,564
JBrowse link
G Zfp36l1 zinc finger protein 36, C3H type-like 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:27182009)
UniProt
RGD
PMID:27182009 GO_REF:0000024 NCBI chr 6:98,930,705...98,935,748
Ensembl chr 6:98,930,718...98,935,748
JBrowse link
sebaceous gland cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fa2h fatty acid 2-hydroxylase acts_upstream_of_or_within ISO MGI:3829000 (MGI:5285470|PMID:21628453) RGD PMID:21628453 MGI:5285470 NCBI chr19:39,312,904...39,364,153
Ensembl chr19:39,312,906...39,364,153
JBrowse link
G Gata6 GATA binding protein 6 involved_in ISO
IEA
(PMID:33082341)
GO_REF:0000107
RGD
Ensembl
PMID:33082341 GO_REF:0000107 NCBI chr18:2,188,121...2,219,532
Ensembl chr18:2,188,121...2,219,532
JBrowse link
vestibular receptor cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grxcr1 glutaredoxin and cysteine rich domain containing 1 involved_in ISO (MGI:3512691|PMID:11276175) RGD PMID:11276175 MGI:3512691 NCBI chr14:40,004,169...40,126,571
Ensembl chr14:40,004,169...40,126,571
JBrowse link
vestibular receptor cell morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptprq protein tyrosine phosphatase, receptor type, Q involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2679316 (MGI:5315778|PMID:22357859)
Ensembl
RGD
PMID:22357859 GO_REF:0000107 MGI:5315778 NCBI chr 7:42,837,109...43,016,917
Ensembl chr 7:42,837,109...43,016,917
JBrowse link
vestibular receptor cell stereocilium organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pls1 plastin 1 involved_in ISO (MGI:5608770|PMID:25124451) RGD PMID:25124451 MGI:5608770 NCBI chr 8:96,316,703...96,426,592
Ensembl chr 8:96,317,849...96,385,195
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20099
    developmental process 7010
      anatomical structure development 6447
        tissue development 2205
          epidermis development 364
            epidermal cell differentiation 243
              epidermal cell fate specification + 4
              hair cell differentiation + 69
              keratinocyte differentiation + 155
              limb basal epidermal cell differentiation + 0
              negative regulation of epidermal cell differentiation + 15
              positive regulation of epidermal cell differentiation + 26
              regulation of epidermal cell differentiation + 60
              sebaceous gland cell differentiation + 2
Path 2
Term Annotations click to browse term
  biological_process 20099
    developmental process 7010
      anatomical structure development 6447
        tissue development 2205
          epithelium development 1373
            epithelial cell differentiation 809
              epidermal cell differentiation 243
                epidermal cell fate specification + 4
                hair cell differentiation + 69
                keratinocyte differentiation + 155
                limb basal epidermal cell differentiation + 0
                negative regulation of epidermal cell differentiation + 15
                positive regulation of epidermal cell differentiation + 26
                regulation of epidermal cell differentiation + 60
                sebaceous gland cell differentiation + 2
paths to the root