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ONTOLOGY REPORT - ANNOTATIONS

Term:cyclic nucleotide binding
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Accession:GO:0030551 term browser browse the term
Definition:Binding to a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue.


show annotations for term's descendants           Sort by:
cyclic nucleotide binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase IDA 2',3'-cAMP, 2',3'-cNADP RGD PMID:19357238 RGD:6480491 NCBI chr10:85,511,164...85,517,723
Ensembl chr10:86,011,495...86,018,063 		JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B IDA RGD PMID:9013543 RGD:61587 NCBI chr 6:27,832,128...27,850,600
Ensembl chr 6:33,558,517...33,568,129 		JBrowse link
G Kcnh1 potassium voltage-gated channel subfamily H member 1 NOT|enables ISS
ISO 		GO_REF:0000024
(PMID:19671703) 		UniProt
RGD		 PMID:19671703 GO_REF:0000024 NCBI chr13:103,722,140...104,024,762
Ensembl chr13:106,253,213...106,555,710 		JBrowse link
2',3'-cyclic GMP-AMP binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc19a1 solute carrier family 19 member 1 enables ISO
IEA 		(PMID:31126740), (PMID:31511694)
GO_REF:0000107 		RGD
Ensembl		 PMID:31126740 PMID:31511694 GO_REF:0000107 NCBI chr20:11,583,928...11,601,959
Ensembl chr20:11,583,929...11,601,488 		JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 enables IDA
IEA
ISO
IBA 		PMID:26669264
GO_REF:0000107
(PMID:23747010), (PMID:26669264), (PMID:30842659), (PMID:30842662), (PMID:35388221)
GO_REF:0000033
(PMID:23258412), (PMID:26300263), (PMID:26669264)
GO_REF:0000117 		Ensembl
RGD
GO_Central
UniProt		 PMID:23258412 PMID:23747010 PMID:26300263 PMID:26669264 PMID:30842659 More... GO_REF:0000033 GO_REF:0000107 GO_REF:0000117, RGD:11344949 NCBI chr18:27,606,196...27,612,544
Ensembl chr18:27,606,196...27,611,947 		JBrowse link
cAMP binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cnbd2 cyclic nucleotide binding domain containing 2 enables ISO
IEA
IBA 		(PMID:24339785)
GO_REF:0000043
GO_REF:0000033 		RGD
UniProt
GO_Central		 PMID:24339785 GO_REF:0000033 GO_REF:0000043 NCBI chr 3:144,819,166...144,884,825
Ensembl chr 3:165,279,204...165,361,688 		JBrowse link
G Cnga1 cyclic nucleotide gated channel subunit alpha 1 enables IEA
ISS
ISO 		GO_REF:0000107
GO_REF:0000043
GO_REF:0000024
(PMID:34699778) 		Ensembl
UniProt
RGD		 PMID:34699778 GO_REF:0000024 GO_REF:0000043 GO_REF:0000107 NCBI chr14:35,920,948...35,959,065
Ensembl chr14:35,926,854...35,959,056 		JBrowse link
G Cnga2 cyclic nucleotide gated channel subunit alpha 2 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr  X:149,696,999...149,715,051
Ensembl chr  X:154,741,764...154,759,814 		JBrowse link
G Cnga4 cyclic nucleotide gated channel subunit alpha 4 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 1:159,752,357...159,756,369
Ensembl chr 1:169,164,206...169,168,224 		JBrowse link
G Cngb1 cyclic nucleotide gated channel subunit beta 1 enables ISO
IEA
IDA 		(PMID:34699778)
GO_REF:0000107
GO_REF:0000043
PMID:27405959 		RGD
Ensembl
UniProt		 PMID:34699778 PMID:27405959 GO_REF:0000043 GO_REF:0000107, RGD:401966869 NCBI chr19:9,732,646...9,798,864
Ensembl chr19:9,732,646...9,797,224 		JBrowse link
G Hcn1 hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 enables ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000043
GO_REF:0000107
(PMID:22006928)
(PMID:28086084) 		UniProt
Ensembl
RGD		 PMID:22006928 PMID:28086084 GO_REF:0000024 GO_REF:0000043 GO_REF:0000107 NCBI chr 2:49,495,771...49,899,983
Ensembl chr 2:51,228,710...51,632,806 		JBrowse link
G Hcn2 hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 7:9,969,801...9,988,839
Ensembl chr 7:10,620,422...10,639,457 		JBrowse link
G Hcn3 hyperpolarization-activated cyclic nucleotide-gated potassium channel 3 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:174,551,861...174,567,459
Ensembl chr 2:176,849,635...176,868,538 		JBrowse link
G Hcn4 hyperpolarization activated cyclic nucleotide-gated potassium channel 4 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 8:59,222,206...59,259,626
Ensembl chr 8:68,118,062...68,155,495 		JBrowse link
G Nme3 NME/NM23 nucleoside diphosphate kinase 3 enables ISO (PMID:39337255) RGD PMID:39337255 NCBI chr10:14,421,922...14,422,878
Ensembl chr10:14,421,702...14,422,907 		JBrowse link
G Pde10a phosphodiesterase 10A enables ISO
IEA 		(PMID:19689430)
GO_REF:0000043 		RGD
UniProt		 PMID:19689430 GO_REF:0000043 NCBI chr 1:51,765,743...52,218,086
Ensembl chr 1:54,317,732...54,764,051 		JBrowse link
G Pde1c phosphodiesterase 1C IDA RGD PMID:7568196 RGD:68318 NCBI chr 4:85,300,858...85,777,948
Ensembl chr 4:86,626,282...87,193,259 		JBrowse link
G Pde2a phosphodiesterase 2A enables ISO (PMID:15938621)
(PMID:15210692) 		RGD PMID:15210692 PMID:15938621 NCBI chr 1:155,823,590...155,915,434
Ensembl chr 1:165,235,623...165,327,466 		JBrowse link
G Pde4a phosphodiesterase 4A enables ISO
IEA 		UniProtKB:P06776|UniProtKB:P22434 (PMID:8413254)
GO_REF:0000107 		RGD
Ensembl		 PMID:8413254 GO_REF:0000107 NCBI chr 8:19,690,816...19,753,538
Ensembl chr 8:27,966,996...28,046,924 		JBrowse link
G Pde4b phosphodiesterase 4B enables ISO
IEA 		UniProtKB:P06776|UniProtKB:P22434 (PMID:8413254)
GO_REF:0000107 		RGD
Ensembl		 PMID:8413254 GO_REF:0000107 NCBI chr 5:122,028,956...122,598,267
Ensembl chr 5:122,135,174...122,598,267 		JBrowse link
G Pde4d phosphodiesterase 4D enables IEA
ISO 		GO_REF:0000107
(PMID:15938621), (PMID:20819076), (PMID:9371713) 		Ensembl
RGD		 PMID:9371713 PMID:15938621 PMID:20819076 GO_REF:0000107 NCBI chr 2:40,014,933...41,529,190
Ensembl chr 2:42,110,838...43,262,569 		JBrowse link
G Popdc1 popeye domain cAMP effector 1 enables IBA
IEA
ISO 		GO_REF:0000033
GO_REF:0000043
(PMID:22354168) 		GO_Central
UniProt
RGD		 PMID:22354168 GO_REF:0000033 GO_REF:0000043 NCBI chr20:48,819,241...48,860,282
Ensembl chr20:50,401,733...50,442,645 		JBrowse link
G Popdc2 popeye domain cAMP effector 2 enables IBA
ISO 		GO_REF:0000033
(PMID:22354168) 		GO_Central
RGD		 PMID:22354168 GO_REF:0000033 NCBI chr11:62,351,843...62,398,688
Ensembl chr11:75,880,274...75,896,269 		JBrowse link
G Popdc3 popeye domain cAMP effector 3 enables IBA
IEA
ISO 		GO_REF:0000033
GO_REF:0000107
(PMID:22354168) 		GO_Central
Ensembl
RGD		 PMID:22354168 GO_REF:0000033 GO_REF:0000107 NCBI chr20:48,772,397...48,800,677
Ensembl chr20:50,354,767...50,385,674 		JBrowse link
G Prkar1a protein kinase cAMP-dependent type I regulatory subunit alpha enables IDA
IEA
IBA 		GO_REF:0000117
GO_REF:0000033
GO_REF:0000043 		UniProt
GO_Central
RGD		 PMID:11907174 GO_REF:0000033 GO_REF:0000043 GO_REF:0000117, RGD:2312572 NCBI chr10:95,120,537...95,139,028
Ensembl chr10:95,120,487...95,139,025 		JBrowse link
G Prkar1b protein kinase cAMP-dependent type I regulatory subunit beta enables IDA
IEA
IBA 		GO_REF:0000117
GO_REF:0000033
GO_REF:0000043 		UniProt
GO_Central
RGD		 PMID:11907174 GO_REF:0000033 GO_REF:0000043 GO_REF:0000117, RGD:2312572 NCBI chr12:15,492,233...15,624,942
Ensembl chr12:20,618,757...20,738,766 		JBrowse link
G Prkar2a protein kinase cAMP-dependent type II regulatory subunit alpha enables IDA
IBA
IEA 		GO_REF:0000033
GO_REF:0000043 		GO_Central
UniProt
RGD		 PMID:11907174 GO_REF:0000033 GO_REF:0000043, RGD:2312572 NCBI chr 8:109,393,189...109,458,832
Ensembl chr 8:118,274,167...118,337,330 		JBrowse link
G Prkar2b protein kinase cAMP-dependent type II regulatory subunit beta enables IDA
IBA
IEA 		GO_REF:0000033
GO_REF:0000043 		GO_Central
UniProt
RGD		 PMID:14625280 PMID:11907174 GO_REF:0000033 GO_REF:0000043, RGD:2312570, RGD:2312572 NCBI chr 6:48,563,659...48,653,933
Ensembl chr 6:54,291,151...54,381,411 		JBrowse link
G Rapgef2 Rap guanine nucleotide exchange factor 2 enables
NOT|enables 		ISO
ISS 		(PMID:10801446)
GO_REF:0000024
(PMID:10548487), (PMID:10608844), (PMID:11359771) 		RGD
UniProt		 PMID:10548487 PMID:10608844 PMID:10801446 PMID:11359771 GO_REF:0000024 NCBI chr 2:164,207,513...164,322,157
Ensembl chr 2:166,505,868...166,726,698 		JBrowse link
G Rapgef3 Rap guanine nucleotide exchange factor 3 enables IPI
IEA 		GO_REF:0000043 UniProt
RGD		 PMID:16244178 GO_REF:0000043, RGD:9850088 NCBI chr 7:128,875,772...128,898,203
Ensembl chr 7:130,754,871...130,777,668 		JBrowse link
G Rapgef4 Rap guanine nucleotide exchange factor 4 enables IDA
IEA
ISO
ISS 		GO_REF:0000117
GO_REF:0000043
(PMID:18660803)
GO_REF:0000024 		UniProt
RGD		 PMID:18660803 PMID:9856955 GO_REF:0000024 GO_REF:0000043 GO_REF:0000117, RGD:632397 NCBI chr 3:56,809,388...57,101,332
Ensembl chr 3:77,217,039...77,509,978 		JBrowse link
G Rapgefl1 Rap guanine nucleotide exchange factor like 1 enables IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr10:83,793,711...83,810,373
Ensembl chr10:84,289,980...84,306,614 		JBrowse link
cGMP binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cnga1 cyclic nucleotide gated channel subunit alpha 1 enables IDA
IEA
IBA
ISO 		GO_REF:0000107
GO_REF:0000043
GO_REF:0000033
GO_REF:0000117
(PMID:34699778) 		Ensembl
UniProt
GO_Central
RGD		 PMID:34699778 PMID:18048449 GO_REF:0000033 GO_REF:0000043 GO_REF:0000107 GO_REF:0000117, RGD:6902904 NCBI chr14:35,920,948...35,959,065
Ensembl chr14:35,926,854...35,959,056 		JBrowse link
G Cnga2 cyclic nucleotide gated channel subunit alpha 2 enables IDA
IBA
IEA 		GO_REF:0000033
GO_REF:0000117
GO_REF:0000043 		GO_Central
UniProt
RGD		 PMID:18048449 PMID:22786723 GO_REF:0000033 GO_REF:0000043 GO_REF:0000117, RGD:6902904, RGD:7241219 NCBI chr  X:149,696,999...149,715,051
Ensembl chr  X:154,741,764...154,759,814 		JBrowse link
G Cnga3 cyclic nucleotide gated channel subunit alpha 3 enables NAS
IEA
IBA
ISO
IDA 		GO_REF:0000107
GO_REF:0000033
GO_REF:0000117
(PMID:24164424), (PMID:37463923) 		Ensembl
GO_Central
UniProt
RGD		 PMID:24164424 PMID:37463923 PMID:10984544 PMID:11387380 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117, RGD:70699, RGD:1600869 NCBI chr 9:46,943,353...46,989,862
Ensembl chr 9:46,928,810...46,989,862 		JBrowse link
G Cnga4 cyclic nucleotide gated channel subunit alpha 4 enables IDA
IBA
IEA 		GO_REF:0000033
GO_REF:0000117 		GO_Central
UniProt
RGD		 PMID:22786723 GO_REF:0000033 GO_REF:0000117, RGD:7241219 NCBI chr 1:159,752,357...159,756,369
Ensembl chr 1:169,164,206...169,168,224 		JBrowse link
G Cngb1 cyclic nucleotide gated channel subunit beta 1 enables ISO
IEA
IBA
IDA 		(PMID:24164424), (PMID:34699778)
GO_REF:0000107
GO_REF:0000117
GO_REF:0000043
GO_REF:0000033
PMID:27405959 		RGD
Ensembl
UniProt
GO_Central		 PMID:24164424 PMID:34699778 PMID:27405959 GO_REF:0000033 GO_REF:0000043 GO_REF:0000107 GO_REF:0000117, RGD:401966869 NCBI chr19:9,732,646...9,798,864
Ensembl chr19:9,732,646...9,797,224 		JBrowse link
G Cngb3 cyclic nucleotide gated channel subunit beta 3 enables ISO
IEA
IBA 		(PMID:24164424), (PMID:37463923)
GO_REF:0000043
GO_REF:0000117
GO_REF:0000107
GO_REF:0000033 		RGD
UniProt
Ensembl
GO_Central		 PMID:24164424 PMID:37463923 GO_REF:0000033 GO_REF:0000043 GO_REF:0000107 GO_REF:0000117 NCBI chr 5:37,543,903...37,792,030
Ensembl chr 5:37,543,903...37,792,030 		JBrowse link
G Pde10a phosphodiesterase 10A enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 1:51,765,743...52,218,086
Ensembl chr 1:54,317,732...54,764,051 		JBrowse link
G Pde11a phosphodiesterase 11A enables ISO
IEA 		(PMID:19689430)
GO_REF:0000107 		RGD
Ensembl		 PMID:19689430 GO_REF:0000107 NCBI chr 3:60,913,562...61,297,154
Ensembl chr 3:81,320,822...81,680,612 		JBrowse link
G Pde2a phosphodiesterase 2A enables ISO
IEA 		(PMID:15938621), (PMID:17329248), (PMID:19689430), (PMID:19828435)
GO_REF:0000043
(PMID:12271124), (PMID:15210692) 		RGD
UniProt		 PMID:12271124 PMID:15210692 PMID:15938621 PMID:17329248 PMID:19689430 More... GO_REF:0000043 NCBI chr 1:155,823,590...155,915,434
Ensembl chr 1:165,235,623...165,327,466 		JBrowse link
G Pde5a phosphodiesterase 5A enables ISO
IEA 		(PMID:12554648), (PMID:18534985)
GO_REF:0000043 		RGD
UniProt		 PMID:12554648 PMID:18534985 GO_REF:0000043 NCBI chr 2:210,858,515...211,003,480
Ensembl chr 2:213,542,923...213,684,298 		JBrowse link
G Pde6g phosphodiesterase 6G enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:106,219,849...106,224,496
Ensembl chr10:106,219,849...106,224,496 		JBrowse link
G Pde6h phosphodiesterase 6H enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:171,588,896...171,604,142
Ensembl chr 4:171,588,974...171,604,249 		JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 enables ISO
IEA 		(PMID:10671526)
GO_REF:0000107
GO_REF:0000043 		RGD
Ensembl
UniProt		 PMID:10671526 GO_REF:0000043 GO_REF:0000107 NCBI chr 1:228,409,605...229,638,794
Ensembl chr 1:237,823,053...239,103,005 		JBrowse link
G Prkg2 protein kinase cGMP-dependent 2 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr14:10,559,882...10,668,479
Ensembl chr14:10,864,186...10,972,614 		JBrowse link
G Rapgef2 Rap guanine nucleotide exchange factor 2 NOT|enables ISO (PMID:10608844), (PMID:11359771) RGD PMID:10608844 PMID:11359771 NCBI chr 2:164,207,513...164,322,157
Ensembl chr 2:166,505,868...166,726,698 		JBrowse link
cyclic-di-GMP binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sting1 stimulator of interferon response cGAMP interactor 1 enables ISO
IEA
IBA 		(PMID:22705373), (PMID:29694889)
GO_REF:0000107
(PMID:21947006), (PMID:26300263)
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:21947006 PMID:22705373 PMID:26300263 PMID:29694889 GO_REF:0000033 GO_REF:0000107 NCBI chr18:27,606,196...27,612,544
Ensembl chr18:27,606,196...27,611,947 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21117
    binding 18258
      nucleoside phosphate binding 2457
        nucleotide binding 2430
          cyclic nucleotide binding 40
            cAMP binding 27
            cGMP binding 15
            cyclic GMP-AMP binding + 2
            cyclic-di-AMP binding 0
            cyclic-di-GMP binding 1
Path 2
Term Annotations click to browse term
  molecular_function 21117
    binding 18258
      small molecule binding 6745
        heterocyclic compound binding 2603
          nucleotide binding 2430
            cyclic nucleotide binding 40
              cAMP binding 27
              cGMP binding 15
              cyclic GMP-AMP binding + 2
              cyclic-di-AMP binding 0
              cyclic-di-GMP binding 1
paths to the root