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ONTOLOGY REPORT - ANNOTATIONS

Term:cyclic nucleotide binding
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Accession:GO:0030551 term browser browse the term
Definition:Binding to a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue.

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cyclic nucleotide binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase IDA 2',3'-cAMP, 2',3'-cNADP RGD PMID:19357238 RGD:6480491 NCBI chr10:88,490,798...88,497,357
Ensembl chr10:88,490,798...88,497,356 		JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B IDA RGD PMID:9013543 RGD:61587 NCBI chr 6:29,975,863...29,987,252
Ensembl chr 6:29,977,797...29,987,451 		JBrowse link
G Kcnh1 potassium voltage-gated channel subfamily H member 1 NOT|enables ISS
ISO		 GO_REF:0000024
(MGI:5616314|PMID:19671703)		 UniProt
RGD		 PMID:19671703 GO_REF:0000024 MGI:5616314 NCBI chr13:110,920,712...111,232,291
Ensembl chr13:110,920,737...111,232,269 		JBrowse link
cAMP binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bves blood vessel epicardial substance enables IBA
ISO		 PMID:21873635
(MGI:5424322|PMID:22354168)		 RGD PMID:22354168, PMID:21873635 MGI:5424322, RGD:13792537 NCBI chr20:50,439,885...50,474,678
Ensembl chr20:50,439,883...50,474,678 		JBrowse link
G Cnbd2 cyclic nucleotide binding domain containing 2 enables IBA
ISO		 PMID:21873635
(MGI:5559917|PMID:24339785)		 RGD PMID:24339785, PMID:21873635 MGI:5559917, RGD:13792537 NCBI chr 3:152,382,245...152,448,105
Ensembl chr 3:152,402,520...152,465,228 		JBrowse link
G Cnga2 cyclic nucleotide gated channel subunit alpha 2 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr16:69,878,513...69,899,075
Ensembl chr 1:69,243,659...69,246,983 		JBrowse link
G Cnga4 cyclic nucleotide gated channel subunit alpha 4 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 1:170,238,959...170,246,858
Ensembl chr 1:170,242,846...170,246,858 		JBrowse link
G Hcn1 hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 enables IEA
ISO
ISS		 GO_REF:0000107
(MGI:5520040|PMID:22006928)
GO_REF:0000024
(PMID:28086084)		 Ensembl
RGD
UniProt		 PMID:22006928 PMID:28086084 GO_REF:0000024 GO_REF:0000107 MGI:5520040 NCBI chr 2:50,099,576...50,499,799
Ensembl chr 2:50,099,576...50,499,799 		JBrowse link
G Hcn2 hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 7:12,851,730...12,870,087
Ensembl chr 7:12,851,739...12,874,215 		JBrowse link
G Hcn3 hyperpolarization-activated cyclic nucleotide-gated potassium channel 3 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:188,458,851...188,471,916
Ensembl chr 2:188,454,853...188,471,988 		JBrowse link
G Hcn4 hyperpolarization activated cyclic nucleotide-gated potassium channel 4 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 8:63,599,907...63,637,327
Ensembl chr 8:63,600,663...63,639,654 		JBrowse link
G Pde10a phosphodiesterase 10A enables ISO (PMID:19689430) RGD PMID:19689430 NCBI chr 1:52,360,296...52,544,448
Ensembl chr 1:52,360,296...52,544,450 		JBrowse link
G Pde1c phosphodiesterase 1C IDA RGD PMID:7568196 RGD:68318 NCBI chr 4:86,359,762...86,925,044
Ensembl chr 4:86,359,820...86,630,543 		JBrowse link
G Pde2a phosphodiesterase 2A enables IEA
ISO		 GO_REF:0000107
(MGI:5294304|PMID:15210692)
(PMID:15938621)		 Ensembl
RGD		 PMID:15210692 PMID:15938621 GO_REF:0000107 MGI:5294304 NCBI chr 1:166,534,643...166,626,158
Ensembl chr 1:166,534,643...166,626,158 		JBrowse link
G Pde4a phosphodiesterase 4A enables ISO
IEA		 UniProtKB:P06776|UniProtKB:P22434 (PMID:8413254)
GO_REF:0000107		 RGD
Ensembl		 PMID:8413254 GO_REF:0000107 NCBI chr 8:22,189,533...22,234,036
Ensembl chr 8:22,189,600...22,233,748 		JBrowse link
G Pde4b phosphodiesterase 4B enables IEA
ISO		 GO_REF:0000107
UniProtKB:P06776|UniProtKB:P22434 (PMID:8413254)		 Ensembl
RGD		 PMID:8413254 GO_REF:0000107 NCBI chr 5:121,759,236...122,136,814
Ensembl chr 5:121,952,977...122,136,814 		JBrowse link
G Pde4d phosphodiesterase 4D enables ISO
IEA		 (PMID:15938621), (PMID:9371713)
GO_REF:0000107
(PMID:20819076)		 RGD
Ensembl		 PMID:9371713 PMID:15938621 PMID:20819076 GO_REF:0000107 NCBI chr 2:40,219,999...41,468,551
Ensembl chr 2:40,554,146...41,464,264 		JBrowse link
G Popdc2 popeye domain containing 2 enables IBA
ISO		 PMID:21873635
(MGI:5424322|PMID:22354168)		 RGD PMID:22354168, PMID:21873635 MGI:5424322, RGD:13792537 NCBI chr11:64,915,041...64,954,704
Ensembl chr11:64,936,692...64,952,687 		JBrowse link
G Popdc3 popeye domain containing 3 enables IBA
ISO		 PMID:21873635
(MGI:5424322|PMID:22354168)		 RGD PMID:22354168, PMID:21873635 MGI:5424322, RGD:13792537 NCBI chr20:50,394,617...50,422,551
Ensembl chr20:50,394,650...50,422,560 		JBrowse link
G Prkar1a protein kinase cAMP-dependent type I regulatory subunit alpha enables IDA
IBA		 PMID:21873635 RGD
GO_Central		 PMID:11907174, PMID:21873635 RGD:2312572, RGD:13792537 NCBI chr10:97,940,705...97,959,199
Ensembl chr10:97,940,705...97,957,336 		JBrowse link
G Prkar1b protein kinase cAMP-dependent type I regulatory subunit beta enables IDA
IBA
IEA		 PMID:21873635
GO_REF:0000043		 UniProt PMID:11907174, PMID:21873635 GO_REF:0000043, RGD:2312572, RGD:13792537 NCBI chr12:17,614,536...17,713,567
Ensembl chr12:17,614,632...17,712,373 		JBrowse link
G Prkar2a protein kinase cAMP-dependent type II regulatory subunit alpha enables IDA
IBA
IEA		 PMID:21873635
GO_REF:0000043		 UniProt PMID:11907174, PMID:21873635 GO_REF:0000043, RGD:2312572, RGD:13792537 NCBI chr 8:117,486,085...117,548,768
Ensembl chr 8:117,486,083...117,546,370 		JBrowse link
G Prkar2b protein kinase cAMP-dependent type II regulatory subunit beta enables IDA
IBA
IEA		 PMID:21873635
GO_REF:0000043		 UniProt PMID:14625280, PMID:21873635, PMID:11907174 GO_REF:0000043, RGD:2312570, RGD:13792537, RGD:2312572 NCBI chr 6:51,265,509...51,356,383
Ensembl chr 6:51,265,515...51,356,383 		JBrowse link
G Rapgef2 Rap guanine nucleotide exchange factor 2 enables
NOT|enables		 ISO
ISS		 (PMID:10801446)
GO_REF:0000024
(PMID:10548487), (PMID:10608844), (PMID:11359771)		 RGD
UniProt		 PMID:10548487 PMID:10608844 PMID:10801446 PMID:11359771 GO_REF:0000024 NCBI chr 2:177,836,191...178,057,378
Ensembl chr 2:177,836,202...178,057,157 		JBrowse link
G Rapgef3 Rap guanine nucleotide exchange factor 3 IPI RGD PMID:16244178 RGD:9850088 NCBI chr 7:139,232,263...139,254,668
Ensembl chr 7:139,232,251...139,254,551 		JBrowse link
G Rapgef4 Rap guanine nucleotide exchange factor 4 enables IDA
ISO
ISS
IEA		 (MGI:4412439|PMID:18660803)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:18660803, PMID:9856955 GO_REF:0000024 GO_REF:0000107 MGI:4412439, RGD:632397 NCBI chr 3:58,632,338...58,925,127
Ensembl chr 3:58,632,476...58,924,038 		JBrowse link
cGMP binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cnga1 cyclic nucleotide gated channel subunit alpha 1 enables IDA
IBA		 PMID:21873635 RGD
GO_Central		 PMID:18048449, PMID:21873635 RGD:6902904, RGD:13792537 NCBI chr14:38,155,771...38,171,107
Ensembl chr14:38,155,759...38,171,010 		JBrowse link
G Cnga2 cyclic nucleotide gated channel subunit alpha 2 enables IDA
IBA		 PMID:21873635 RGD
GO_Central		 PMID:18048449, PMID:21873635, PMID:22786723 RGD:6902904, RGD:13792537, RGD:7241219 NCBI chr16:69,878,513...69,899,075
Ensembl chr 1:69,243,659...69,246,983 		JBrowse link
G Cnga3 cyclic nucleotide gated channel subunit alpha 3 enables NAS
IBA
ISO
IDA		 PMID:21873635
(PMID:24164424)		 RGD PMID:24164424, PMID:10984544, PMID:21873635, PMID:11387380 RGD:70699, RGD:13792537, RGD:1600869 NCBI chr 9:43,807,412...43,858,225
Ensembl chr 9:43,807,677...43,854,396 		JBrowse link
G Cnga4 cyclic nucleotide gated channel subunit alpha 4 enables IDA
IBA		 PMID:21873635 RGD
GO_Central		 PMID:22786723, PMID:21873635 RGD:7241219, RGD:13792537 NCBI chr 1:170,238,959...170,246,858
Ensembl chr 1:170,242,846...170,246,858 		JBrowse link
G Cngb1 cyclic nucleotide gated channel subunit beta 1 enables IBA
ISO		 PMID:21873635
(PMID:24164424)		 RGD PMID:24164424, PMID:21873635 RGD:13792537 NCBI chr19:10,142,440...10,206,618
Ensembl chr19:10,142,496...10,206,681 		JBrowse link
G Cngb3 cyclic nucleotide gated channel subunit beta 3 enables ISO
IBA		 (PMID:24164424)
PMID:21873635		 RGD PMID:24164424, PMID:21873635 RGD:13792537 NCBI chr 5:33,097,353...33,507,467
Ensembl chr 5:33,097,654...33,507,467 		JBrowse link
G LOC108348053 cyclic nucleotide-gated olfactory channel enables IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:69,873,485...69,877,475
Ensembl chr16:69,873,463...69,935,986 		JBrowse link
G Pde10a phosphodiesterase 10A enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 1:52,360,296...52,544,448
Ensembl chr 1:52,360,296...52,544,450 		JBrowse link
G Pde11a phosphodiesterase 11A enables ISO (PMID:19689430) RGD PMID:19689430 NCBI chr 3:62,818,502...63,211,843
Ensembl chr 3:62,818,502...63,211,845 		JBrowse link
G Pde2a phosphodiesterase 2A enables ISO
IEA		 (PMID:15938621), (PMID:17329248), (PMID:19689430), (PMID:19828435)
(MGI:5294304|PMID:15210692), (MGI:5294310|PMID:12271124)
GO_REF:0000107		 RGD
Ensembl		 PMID:12271124 PMID:15210692 PMID:15938621 PMID:17329248 PMID:19689430 PMID:19828435 GO_REF:0000107 MGI:5294304 MGI:5294310 NCBI chr 1:166,534,643...166,626,158
Ensembl chr 1:166,534,643...166,626,158 		JBrowse link
G Pde5a phosphodiesterase 5A enables IEA
ISO		 GO_REF:0000107
(MGI:2450821|PMID:12554648), (MGI:3810583|PMID:18534985)		 Ensembl
RGD		 PMID:12554648 PMID:18534985 GO_REF:0000107 MGI:2450821 MGI:3810583 NCBI chr 2:226,899,604...227,044,916
Ensembl chr 2:226,900,619...227,041,576 		JBrowse link
G Pde6g phosphodiesterase 6G enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:109,620,499...109,625,214
Ensembl chr10:109,620,980...109,622,745 		JBrowse link
G Pde6h phosphodiesterase 6H enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:170,947,723...170,963,046
Ensembl chr 4:170,958,196...170,963,046 		JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 enables ISO (MGI:1890119|PMID:10671526) RGD PMID:10671526 MGI:1890119 NCBI chr 1:248,982,039...250,300,952 JBrowse link
G Prkg2 protein kinase cGMP-dependent 2 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr14:12,217,121...12,313,616
Ensembl chr14:12,218,553...12,315,229 		JBrowse link
G Rapgef2 Rap guanine nucleotide exchange factor 2 NOT|enables ISO (PMID:10608844), (PMID:11359771) RGD PMID:10608844 PMID:11359771 NCBI chr 2:177,836,191...178,057,378
Ensembl chr 2:177,836,202...178,057,157 		JBrowse link
cyclic-di-GMP binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sting1 stimulator of interferon response cGAMP interactor 1 enables ISO
IBA		 (PMID:22705373), (PMID:29694889)
(MGI:5487515|PMID:21947006), (MGI:5700266|PMID:26300263)
PMID:21873635		 RGD PMID:21947006 PMID:22705373 PMID:26300263 PMID:29694889, PMID:21873635 MGI:5487515 MGI:5700266, RGD:13792537 NCBI chr18:28,529,537...28,535,828
Ensembl chr18:28,529,576...28,535,828 		JBrowse link
cyclic-GMP-AMP binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc19a1 solute carrier family 19 member 1 enables ISO (PMID:31126740), (PMID:31511694) RGD PMID:31126740 PMID:31511694 NCBI chr20:12,334,675...12,354,517
Ensembl chr20:12,334,676...12,352,377 		JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 enables IDA
ISO
IBA		 PMID:26669264
(PMID:23747010), (PMID:26669264), (PMID:30842659), (PMID:30842662)
PMID:21873635
(MGI:5487473|PMID:23258412), (MGI:5700266|PMID:26300263), (MGI:5787716|PMID:26669264)		 RGD PMID:23258412 PMID:23747010 PMID:26300263 PMID:26669264 PMID:30842659 PMID:30842662, PMID:26669264, PMID:21873635 MGI:5487473 MGI:5700266 MGI:5787716, RGD:11344949, RGD:13792537 NCBI chr18:28,529,537...28,535,828
Ensembl chr18:28,529,576...28,535,828 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 19986
    binding 17016
      small molecule binding 2502
        nucleotide binding 2130
          cyclic nucleotide binding 39
            2',5-3',5'-cyclic GMP-AMP binding 0
            cAMP binding 23
            cGMP binding 16
            cyclic-GMP-AMP binding 2
            cyclic-di-GMP binding 1
Path 2
Term Annotations click to browse term
  molecular_function 19986
    binding 17016
      organic cyclic compound binding 5709
        nucleoside phosphate binding 2130
          nucleotide binding 2130
            cyclic nucleotide binding 39
              2',5-3',5'-cyclic GMP-AMP binding 0
              cAMP binding 23
              cGMP binding 16
              cyclic-GMP-AMP binding 2
              cyclic-di-GMP binding 1
paths to the root