Gene: Cnga1 (cyclic nucleotide gated channel alpha 1) Rattus norvegicus
Analyze
Symbol: Cnga1
Name: cyclic nucleotide gated channel alpha 1
Description: ENCODES a protein that exhibits cGMP binding; intracellular cGMP-activated cation channel activity; INVOLVED IN membrane depolarization; regulation of cytosolic calcium ion concentration; spermatogenesis; PARTICIPATES IN altered visual phototransduction pathway; calcium/calcium-mediated signaling pathway; retinitis pigmentosa pathway; ASSOCIATED WITH fundus dystrophy (ortholog); prostate cancer (ortholog); retinitis pigmentosa (ortholog); FOUND IN cytoplasm; intracellular cyclic nucleotide activated cation channel complex; terminal bouton; INTERACTS WITH 1,2-dimethylhydrazine; 17beta-estradiol 3-benzoate; 6-propyl-2-thiouracil
AGR Description: Exhibits cGMP binding activity and intracellular cGMP-activated cation channel activity; involved in membrane depolarization, regulation of cytosolic calcium ion concentration, and spermatogenesis; localizes to the cytoplasm, intracellular cyclic nucleotide activated cation channel complex, and terminal bouton; orthologous to human CNGA1 (cyclic nucleotide gated channel alpha 1).
Merged Description: Exhibits cGMP binding activity and intracellular cGMP-activated cation channel activity; involved in membrane depolarization, regulation of cytosolic calcium ion concentration, and spermatogenesis; localizes to the cytoplasm, intracellular cyclic nucleotide activated cation channel complex, and terminal bouton; orthologous to human CNGA1 (cyclic nucleotide gated channel alpha 1); PARTICIPATES IN altered visual phototransduction pathway; calcium/calcium-mediated signaling pathway; retinitis pigmentosa pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17beta-estradiol 3-benzoate; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: cGMP-gated cation channel alpha-1; Cncg; CNG channel alpha-1; CNG-1; CNG1; cyclic nucleotide-gated cation channel; cyclic nucleotide-gated cation channel 1; cyclic nucleotide-gated channel alpha-1; cyclic nucleotide-gated channel, photoreceptor; HCN; rod photoreceptor cGMP-gated channel subunit alpha
Orthologs:
Homo sapiens (human) : CNGA1 (cyclic nucleotide gated channel alpha 1)  HGNC  Alliance
Mus musculus (house mouse) : Cnga1 (cyclic nucleotide gated channel alpha 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cnga1 (cyclic nucleotide gated channel alpha 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CNGA1 (cyclic nucleotide gated channel alpha 1)
Canis lupus familiaris (dog) : CNGA1 (cyclic nucleotide gated channel alpha 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cnga1 (cyclic nucleotide gated channel alpha 1)
Sus scrofa (pig) : CNGA1 (cyclic nucleotide gated channel alpha 1)
more info ...
Is Marker For: Strains:   SD  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01438,155,771 - 38,171,107 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01437,966,503 - 37,981,839 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41438,017,762 - 38,033,098 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11438,021,111 - 38,036,448 (+)NCBI
Celera1434,842,269 - 34,857,640 (+)NCBICelera
Cytogenetic Map14p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Cnga1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621815
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.