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ONTOLOGY REPORT - ANNOTATIONS

Term:cAMP binding
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Accession:GO:0030552 term browser browse the term
Definition:Binding to cAMP, the nucleotide cyclic AMP (adenosine 3',5'-cyclophosphate).
Synonyms:exact_synonym: 3',5' cAMP binding;   adenosine 3',5'-cyclophosphate binding;   cyclic AMP binding
 xref: Reactome:R-HSA-111925 "cAMP induces dissociation of inactive PKA tetramers";   Reactome:R-HSA-381608 "cAMP activates EPAC2";   Reactome:R-HSA-381668 "cAMP activates EPAC1";   Reactome:R-HSA-381707 "PKA:AKAP79:IQGAP1 complex dissociates to active PKA subunits in response to cAMP"


show annotations for term's descendants           Sort by:
cAMP binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cnbd2 cyclic nucleotide binding domain containing 2 enables ISO (PMID:24339785) RGD PMID:24339785 NCBI chr 3:144,819,166...144,884,825
Ensembl chr 3:144,819,195...144,901,583 		JBrowse link
G Cnga1 cyclic nucleotide gated channel subunit alpha 1 enables IEA
ISO
ISS		 GO_REF:0000107
(PMID:34699778)
GO_REF:0000024
GO_REF:0000043		 Ensembl
RGD
UniProt		 PMID:34699778 GO_REF:0000024 GO_REF:0000043 GO_REF:0000107 NCBI chr14:35,566,947...35,605,065
Ensembl chr14:35,567,125...35,605,065 		JBrowse link
G Cnga2 cyclic nucleotide gated channel subunit alpha 2 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr  X:149,696,999...149,715,051
Ensembl chr  X:149,696,997...149,715,051 		JBrowse link
G Cnga4 cyclic nucleotide gated channel subunit alpha 4 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 1:159,752,357...159,756,369
Ensembl chr 1:159,752,357...159,756,375 		JBrowse link
G Cngb1 cyclic nucleotide gated channel subunit beta 1 enables ISO
IDA		 (PMID:34699778)
PMID:27405959		 RGD PMID:34699778 PMID:27405959 RGD:401966869 NCBI chr19:9,726,595...9,791,111
Ensembl chr19:9,726,595...9,791,173 		JBrowse link
G Hcn1 hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 enables ISS
ISO		 GO_REF:0000024
(PMID:28086084)
(PMID:22006928)		 UniProt
RGD		 PMID:22006928 PMID:28086084 GO_REF:0000024 NCBI chr 2:49,495,771...49,899,983
Ensembl chr 2:49,495,771...49,899,774 		JBrowse link
G Hcn2 hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 7:9,969,801...9,988,839
Ensembl chr 7:9,970,368...9,988,841 		JBrowse link
G Hcn3 hyperpolarization-activated cyclic nucleotide-gated potassium channel 3 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:174,551,861...174,567,459
Ensembl chr 2:174,551,680...174,565,966 		JBrowse link
G Hcn4 hyperpolarization activated cyclic nucleotide-gated potassium channel 4 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 8:59,222,206...59,259,626
Ensembl chr 8:59,221,653...59,259,639 		JBrowse link
G Pde10a phosphodiesterase 10A enables ISO
IEA		 (PMID:19689430)
GO_REF:0000107		 RGD
Ensembl		 PMID:19689430 GO_REF:0000107 NCBI chr 1:51,765,743...52,218,086
Ensembl chr 1:51,770,132...52,216,563 		JBrowse link
G Pde1c phosphodiesterase 1C IDA RGD PMID:7568196 RGD:68318 NCBI chr 4:85,300,858...85,777,948
Ensembl chr 4:85,300,858...85,863,219 		JBrowse link
G Pde2a phosphodiesterase 2A enables IEA
ISO		 GO_REF:0000107
(PMID:15938621)
(PMID:15210692)		 Ensembl
RGD		 PMID:15210692 PMID:15938621 GO_REF:0000107 NCBI chr 1:155,823,590...155,915,434
Ensembl chr 1:155,813,180...155,915,434 		JBrowse link
G Pde4a phosphodiesterase 4A enables ISO
IEA		 UniProtKB:P06776|UniProtKB:P22434 (PMID:8413254)
GO_REF:0000107		 RGD
Ensembl		 PMID:8413254 GO_REF:0000107 NCBI chr 8:19,690,816...19,753,538
Ensembl chr 8:19,703,290...19,751,961 		JBrowse link
G Pde4b phosphodiesterase 4B enables ISO
IEA		 UniProtKB:P06776|UniProtKB:P22434 (PMID:8413254)
GO_REF:0000107		 RGD
Ensembl		 PMID:8413254 GO_REF:0000107 NCBI chr 5:116,799,819...117,369,155
Ensembl chr 5:116,799,971...117,367,696 		JBrowse link
G Pde4d phosphodiesterase 4D enables IEA
ISO		 GO_REF:0000107
(PMID:15938621), (PMID:20819076), (PMID:9371713)		 Ensembl
RGD		 PMID:9371713 PMID:15938621 PMID:20819076 GO_REF:0000107 NCBI chr 2:40,014,933...41,529,190
Ensembl chr 2:40,019,933...41,525,884 		JBrowse link
G Popdc1 popeye domain cAMP effector 1 enables IBA
ISO		 GO_REF:0000033
(PMID:22354168)		 GO_Central
RGD		 PMID:22354168 GO_REF:0000033 NCBI chr20:48,819,241...48,860,282
Ensembl chr20:48,822,308...48,857,472 		JBrowse link
G Popdc2 popeye domain cAMP effector 2 enables IBA
ISO		 GO_REF:0000033
(PMID:22354168)		 GO_Central
RGD		 PMID:22354168 GO_REF:0000033 NCBI chr11:62,351,843...62,398,688
Ensembl chr11:62,374,759...62,390,756 		JBrowse link
G Popdc3 popeye domain cAMP effector 3 enables IBA
ISO		 GO_REF:0000033
(PMID:22354168)		 GO_Central
RGD		 PMID:22354168 GO_REF:0000033 NCBI chr20:48,772,397...48,800,677
Ensembl chr20:48,772,462...48,800,593 		JBrowse link
G Prkar1a protein kinase cAMP-dependent type I regulatory subunit alpha enables IDA
IEA
IBA		 GO_REF:0000043
GO_REF:0000033		 UniProt
GO_Central
RGD		 PMID:11907174 GO_REF:0000033 GO_REF:0000043, RGD:2312572 NCBI chr10:94,621,042...94,639,534
Ensembl chr10:94,620,039...94,639,041 		JBrowse link
G Prkar1b protein kinase cAMP-dependent type I regulatory subunit beta enables IDA
IEA
IBA		 GO_REF:0000043
GO_REF:0000033		 UniProt
GO_Central
RGD		 PMID:11907174 GO_REF:0000033 GO_REF:0000043, RGD:2312572 NCBI chr12:15,492,233...15,624,942
Ensembl chr12:15,511,801...15,624,942 		JBrowse link
G Prkar2a protein kinase cAMP-dependent type II regulatory subunit alpha enables IDA
IEA
IBA		 GO_REF:0000043
GO_REF:0000033		 UniProt
GO_Central
RGD		 PMID:11907174 GO_REF:0000033 GO_REF:0000043, RGD:2312572 NCBI chr 8:109,393,189...109,458,832
Ensembl chr 8:109,395,833...109,455,628 		JBrowse link
G Prkar2b protein kinase cAMP-dependent type II regulatory subunit beta enables IDA
IEA
IBA		 GO_REF:0000043
GO_REF:0000033		 UniProt
GO_Central
RGD		 PMID:14625280 PMID:11907174 GO_REF:0000033 GO_REF:0000043, RGD:2312570, RGD:2312572 NCBI chr 6:48,563,659...48,653,933
Ensembl chr 6:48,563,662...48,653,933 		JBrowse link
G Rapgef2 Rap guanine nucleotide exchange factor 2 enables
NOT|enables		 ISO
ISS		 (PMID:10801446)
(PMID:10548487), (PMID:10608844), (PMID:11359771)
GO_REF:0000024		 RGD
UniProt		 PMID:10548487 PMID:10608844 PMID:10801446 PMID:11359771 GO_REF:0000024 NCBI chr 2:164,207,513...164,322,157
Ensembl chr 2:164,207,513...164,244,247 		JBrowse link
G Rapgef3 Rap guanine nucleotide exchange factor 3 IPI RGD PMID:16244178 RGD:9850088 NCBI chr 7:128,875,772...128,898,203
Ensembl chr 7:128,875,773...128,898,521 		JBrowse link
G Rapgef4 Rap guanine nucleotide exchange factor 4 enables IDA
IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:18660803)		 Ensembl
UniProt
RGD		 PMID:18660803 PMID:9856955 GO_REF:0000024 GO_REF:0000107, RGD:632397 NCBI chr 3:56,809,388...57,101,332
Ensembl chr 3:56,809,270...57,102,316 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20633
    binding 17721
      small molecule binding 6195
        ion binding 5913
          anion binding 2535
            cAMP binding 25
Path 2
Term Annotations click to browse term
  molecular_function 20633
    binding 17721
      organic cyclic compound binding 6136
        nucleoside phosphate binding 2284
          nucleotide binding 2257
            purine nucleotide binding 2089
              purine ribonucleotide binding 1949
                adenyl ribonucleotide binding 1567
                  cAMP binding 25
paths to the root