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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of stress-activated protein kinase signaling cascade
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Accession:GO:0070302 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of signaling via a stress-activated protein kinase signaling cascade.
Synonyms:exact_synonym: regulation of SAPK signaling pathway;   regulation of stress-activated protein kinase signaling pathway;   regulation of stress-activated protein kinase signalling pathway


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regulation of stress-activated protein kinase signaling cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zmpste24 zinc metallopeptidase STE24 acts_upstream_of_or_within ISO MGI:2180033 (PMID:16079796) RGD PMID:16079796 NCBI chr 5:134,627,218...134,660,360
Ensembl chr 5:134,627,229...134,660,110 		JBrowse link
negative regulation of stress-activated MAPK cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dusp10 dual specificity phosphatase 10 acts_upstream_of_or_within ISO MGI:3052343 (PMID:19696743) RGD PMID:19696743 NCBI chr13:95,613,716...95,651,716
Ensembl chr13:95,614,292...95,651,716 		JBrowse link
G Foxm1 forkhead box M1 involved_in ISO
IEA		 (PMID:19696738)
GO_REF:0000107		 RGD
Ensembl		 PMID:19696738 GO_REF:0000107 NCBI chr 4:161,639,538...161,652,012
Ensembl chr 4:161,638,816...161,650,684 		JBrowse link
G Foxo1 forkhead box O1 involved_in ISO (PMID:19696738) RGD PMID:19696738 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:16023107)		 BHF-UCL
RGD		 PMID:16023107 GO_REF:0000024 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Igbp1 immunoglobulin binding protein 1 involved_in ISO (PMID:17438131) RGD PMID:17438131 NCBI chr  X:65,582,832...65,605,078
Ensembl chr  X:65,582,821...65,606,049 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor involved_in ISO (PMID:19545562) RGD PMID:19545562 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Pbk PDZ binding kinase acts_upstream_of_or_within ISO MGI:5293435 (PMID:21715333) RGD PMID:21715333 NCBI chr15:40,022,873...40,034,014
Ensembl chr15:40,023,002...40,034,014 		JBrowse link
G Ppia peptidylprolyl isomerase A involved_in ISS
ISO		 GO_REF:0000024
(PMID:26095851)		 UniProt
RGD		 PMID:26095851 GO_REF:0000024 NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601 		JBrowse link
G Ppial4d peptidylprolyl isomerase A (cyclophilin A)-like 4D involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr14:21,006,522...21,007,284
Ensembl chr14:21,006,538...21,007,310 		JBrowse link
G Qars1 glutaminyl-tRNA synthetase 1 involved_in ISO
IEA		 (PMID:11096076)
GO_REF:0000107		 RGD
Ensembl		 PMID:11096076 GO_REF:0000107 NCBI chr 8:109,207,705...109,215,738
Ensembl chr 8:109,207,705...109,215,739 		JBrowse link
negative regulation of stress-activated protein kinase signaling cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Map3k20 mitogen-activated protein kinase kinase kinase 20 involved_in ISO (PMID:35857590) RGD PMID:35857590 NCBI chr 3:57,130,539...57,289,943
Ensembl chr 3:57,130,551...57,289,626 		JBrowse link
positive regulation of stress-activated MAPK cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arl6ip5 ARF like GTPase 6 interacting protein 5 involved_in IEA
ISO		 GO_REF:0000107
(PMID:18387645)		 Ensembl
RGD		 PMID:18387645 GO_REF:0000107 NCBI chr 4:129,810,650...129,838,628
Ensembl chr 4:129,810,645...129,838,608 		JBrowse link
G Card9 caspase recruitment domain family, member 9 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
(PMID:17187069)
MGI:3698412 (PMID:17187069)
(PMID:29080677)		 UniProt
RGD		 PMID:17187069 PMID:29080677 GO_REF:0000024 NCBI chr 3:9,171,814...9,180,310
Ensembl chr 3:9,171,815...9,180,237 		JBrowse link
G Clec7a C-type lectin domain containing 7A involved_in ISO (PMID:27288407) RGD PMID:27288407 NCBI chr 4:162,902,731...162,913,931
Ensembl chr 4:162,902,732...162,913,897 		JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 IMP RGD PMID:19211730 RGD:5130956 NCBI chr 4:84,222,897...84,265,924
Ensembl chr 4:84,224,002...84,265,904 		JBrowse link
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:20038207)		 UniProt
RGD		 PMID:20038207 GO_REF:0000024 NCBI chr 6:16,189,000...16,224,972
Ensembl chr 6:16,188,979...16,224,971 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase IMP RGD PMID:17161379 RGD:5508698 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703 		JBrowse link
G Igfbp6 insulin-like growth factor binding protein 6 involved_in ISO (PMID:24003225) RGD PMID:24003225 NCBI chr 7:133,276,309...133,280,944
Ensembl chr 7:133,276,234...133,280,966 		JBrowse link
G Il1a interleukin 1 alpha IDA RGD PMID:15671867 RGD:1358666 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta IMP
IDA		 RGD PMID:12629164 PMID:15671867 RGD:1626685, RGD:1358666 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Inava innate immunity activator involved_in ISO (PMID:28436939) RGD PMID:28436939 NCBI chr13:47,666,446...47,687,383
Ensembl chr13:47,666,447...47,686,729 		JBrowse link
G Kiss1 KiSS-1 metastasis-suppressor NOT IMP RGD PMID:16222076 RGD:1599289 NCBI chr13:44,775,106...44,780,707
Ensembl chr13:44,774,823...44,780,612 		JBrowse link
G Klhdc10 kelch domain containing 10 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:59,021,300...59,079,118
Ensembl chr 4:59,021,310...59,074,941 		JBrowse link
G Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 IMP RGD PMID:12024021 RGD:2302280 NCBI chr 7:120,526,732...120,536,982
Ensembl chr 7:120,526,732...120,536,982 		JBrowse link
G Mid1 midline 1 involved_in ISO (PMID:17438131) RGD PMID:17438131 NCBI chr  X:24,116,674...24,491,205
Ensembl chr  X:24,120,293...24,248,353 		JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 acts_upstream_of_or_within ISO (PMID:18261938) RGD PMID:18261938 NCBI chr 4:84,060,871...84,111,668
Ensembl chr 4:84,060,880...84,111,404 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (PMID:17187069)
(PMID:18261938)		 RGD PMID:17187069 PMID:18261938 NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Pdcd10 programmed cell death 10 involved_in ISO
IEA		 (PMID:22652780)
GO_REF:0000107		 RGD
Ensembl		 PMID:22652780 GO_REF:0000107 NCBI chr 2:160,303,465...160,346,086
Ensembl chr 2:160,303,449...160,346,018 		JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 acts_upstream_of_or_within ISO MGI:2446070|MGI:2660793 (PMID:11894097), (PMID:11894098), (PMID:18261938) RGD PMID:11894097 PMID:11894098 PMID:18261938 NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657 		JBrowse link
G Scimp SLP adaptor and CSK interacting membrane protein involved_in ISO (PMID:27288407) RGD PMID:27288407 NCBI chr10:55,507,646...55,527,764
Ensembl chr10:55,507,519...55,528,171 		JBrowse link
G Sema4c semaphorin 4C involved_in ISO (PMID:17498836) RGD PMID:17498836 NCBI chr 9:38,791,668...38,802,171
Ensembl chr 9:38,791,670...38,802,128 		JBrowse link
G Stk25 serine/threonine kinase 25 involved_in ISO (PMID:22652780) RGD PMID:22652780 NCBI chr 9:94,161,834...94,174,095
Ensembl chr 9:94,161,836...94,174,244 		JBrowse link
G Taok1 TAO kinase 1 involved_in ISO
ISS
IBA		 (PMID:17396146)
GO_REF:0000024
GO_REF:0000033		 RGD
UniProt
GO_Central		 PMID:17396146 GO_REF:0000024 GO_REF:0000033 NCBI chr10:62,373,072...62,465,295
Ensembl chr10:62,381,404...62,465,766 		JBrowse link
G Taok2 TAO kinase 2 involved_in ISO
ISS
IEA		 (PMID:17396146)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:17396146 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:181,475,708...181,494,738
Ensembl chr 1:181,475,711...181,494,613 		JBrowse link
G Taok3 TAO kinase 3 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:17396146)		 UniProt
Ensembl
RGD		 PMID:17396146 GO_REF:0000024 GO_REF:0000107 NCBI chr12:39,312,354...39,473,656
Ensembl chr12:39,314,027...39,461,244 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:17192487)		 AgBase
RGD		 PMID:17192487 GO_REF:0000024 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
G Tlr4 toll-like receptor 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:18261938)		 Ensembl
RGD		 PMID:18261938 GO_REF:0000107 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
regulation of stress-activated MAPK cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENSRNOG00000067941 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 Ensembl chr11:42,352,734...42,354,134 JBrowse link
G Fas Fas cell surface death receptor involved_in ISO
IBA		 (PMID:11096076)
GO_REF:0000033		 RGD
GO_Central		 PMID:11096076 GO_REF:0000033 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist NOT|involved_in ISO (PMID:12135612) RGD PMID:12135612 NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:10945608)		 BHF-UCL
RGD		 PMID:10945608 GO_REF:0000024 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 involved_in TAS
IEA		 PMID:19565474
GO_REF:0000117		 UniProt PMID:19565474 GO_REF:0000117, RGD:8553538 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147 		JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 involved_in TAS
IEA		 PMID:19565474
GO_REF:0000117		 UniProt PMID:19565474 GO_REF:0000117, RGD:8553538 NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 involved_in TAS
IEA		 PMID:19565474
GO_REF:0000117		 UniProt PMID:19565474 GO_REF:0000117, RGD:8553538 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 involved_in TAS
IEA		 PMID:19565474
GO_REF:0000117		 UniProt PMID:19565474 GO_REF:0000117, RGD:8553538 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Nbr1 NBR1, autophagy cargo receptor involved_in IEA
ISO		 GO_REF:0000107
(PMID:20616007)		 Ensembl
RGD		 PMID:20616007 GO_REF:0000107 NCBI chr10:86,477,775...86,506,418
Ensembl chr10:86,478,290...86,506,412 		JBrowse link
G Prdx1 peroxiredoxin 1 acts_upstream_of_or_within ISO (PMID:16880205) RGD PMID:16880205 NCBI chr 5:130,147,258...130,162,856
Ensembl chr 5:130,147,204...130,162,856 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20228
    regulation of biological process 13203
      regulation of cellular process 12840
        regulation of cellular response to stress 506
          regulation of stress-activated protein kinase signaling cascade 47
            negative regulation of stress-activated protein kinase signaling cascade + 11
            positive regulation of stress-activated protein kinase signaling cascade + 26
            regulation of stress-activated MAPK cascade + 45
Path 2
Term Annotations click to browse term
  biological_process 20228
    biological regulation 13626
      regulation of biological process 13203
        signaling 7760
          signal transduction 7199
            regulation of signal transduction 3285
              regulation of intracellular signal transduction 2083
                regulation of stress-activated protein kinase signaling cascade 47
                  negative regulation of stress-activated protein kinase signaling cascade + 11
                  positive regulation of stress-activated protein kinase signaling cascade + 26
                  regulation of stress-activated MAPK cascade + 45
paths to the root