Klhdc10 (kelch domain containing 10) - Rat Genome Database

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Pathways
Gene: Klhdc10 (kelch domain containing 10) Rattus norvegicus
Analyze
Symbol: Klhdc10
Name: kelch domain containing 10
RGD ID: 1309792
Description: Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in positive regulation of stress-activated MAPK cascade; rescue of stalled ribosome; and ubiquitin-dependent protein catabolic process via the C-end degron rule pathway. Predicted to be located in nucleoplasm. Predicted to be part of Cul2-RING ubiquitin ligase complex. Predicted to be active in cytoplasm. Orthologous to human KLHDC10 (kelch domain containing 10); INTERACTS WITH acetamide; bisphenol A; furan.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: kelch domain-containing protein 10; LOC312199; RGD1309792; similar to scruin like at the midline CG5186-PA
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8459,988,710 - 60,046,518 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl459,988,646 - 60,046,516 (+)EnsemblGRCr8
mRatBN7.2459,021,300 - 59,079,118 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl459,021,310 - 59,074,941 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx463,999,425 - 64,053,045 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0459,915,612 - 59,969,232 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0458,317,528 - 58,371,151 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0457,715,982 - 57,773,800 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl457,715,946 - 57,773,823 (+)Ensemblrn6Rnor6.0
Rnor_5.0457,477,620 - 57,535,303 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4457,312,274 - 57,365,922 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera454,120,564 - 54,174,023 (+)NCBICelera
RGSC_v3.1457,588,403 - 57,642,052 (+)NCBI
Cytogenetic Map4q22NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
Cul2-RING ubiquitin ligase complex  (IEA,ISO,ISS)
cytoplasm  (IEA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932  


Genomics

Comparative Map Data
Klhdc10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8459,988,710 - 60,046,518 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl459,988,646 - 60,046,516 (+)EnsemblGRCr8
mRatBN7.2459,021,300 - 59,079,118 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl459,021,310 - 59,074,941 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx463,999,425 - 64,053,045 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0459,915,612 - 59,969,232 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0458,317,528 - 58,371,151 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0457,715,982 - 57,773,800 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl457,715,946 - 57,773,823 (+)Ensemblrn6Rnor6.0
Rnor_5.0457,477,620 - 57,535,303 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4457,312,274 - 57,365,922 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera454,120,564 - 54,174,023 (+)NCBICelera
RGSC_v3.1457,588,403 - 57,642,052 (+)NCBI
Cytogenetic Map4q22NCBI
KLHDC10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387130,070,534 - 130,135,705 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7130,070,534 - 130,135,705 (+)Ensemblhg38GRCh38
GRCh377129,710,374 - 129,775,545 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367129,497,585 - 129,560,829 (+)NCBIBuild 36Build 36hg18NCBI36
Celera7124,506,108 - 124,571,332 (+)NCBICelera
Cytogenetic Map7q32.2NCBI
HuRef7124,072,999 - 124,138,082 (+)NCBIHuRef
CHM1_17129,643,789 - 129,709,160 (+)NCBICHM1_1
T2T-CHM13v2.07131,383,894 - 131,449,088 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27129,095,715 - 129,160,935 (+)NCBI
Klhdc10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39630,401,516 - 30,455,178 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl630,401,867 - 30,455,178 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38630,401,517 - 30,455,179 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl630,401,868 - 30,455,179 (+)Ensemblmm10GRCm38
MGSCv37630,351,909 - 30,405,174 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36630,351,919 - 30,405,184 (+)NCBIMGSCv36mm8
Celera630,411,890 - 30,465,194 (+)NCBICelera
Cytogenetic Map6A3.3NCBI
cM Map612.52NCBI
Klhdc10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547910,743,661 - 10,799,845 (+)Ensembl
ChiLan1.0NW_00495547910,743,658 - 10,826,129 (+)NCBIChiLan1.0ChiLan1.0
KLHDC10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26166,890,888 - 166,957,201 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1718,901,880 - 18,967,460 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07122,036,564 - 122,101,840 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17134,555,062 - 134,620,225 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7134,555,062 - 134,620,225 (+)EnsemblpanPan2panpan1.1
KLHDC10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1146,750,269 - 6,771,690 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl146,755,070 - 6,781,604 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha146,436,275 - 6,498,255 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0146,511,577 - 6,573,810 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl146,511,580 - 6,573,859 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1146,721,799 - 6,778,993 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0146,460,981 - 6,522,979 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0146,604,954 - 6,667,138 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Klhdc10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511824,954,264 - 25,010,407 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365795,087,028 - 5,142,253 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365795,082,221 - 5,143,004 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KLHDC10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1818,667,365 - 18,723,067 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11818,667,377 - 18,723,090 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21819,582,868 - 19,629,579 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KLHDC10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12198,702,411 - 98,773,299 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2198,702,451 - 98,768,343 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660424,631,111 - 4,699,692 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Klhdc10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247836,118,829 - 6,188,611 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247836,118,814 - 6,188,198 (-)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Klhdc10
274 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:85
Count of miRNA genes:80
Interacting mature miRNAs:83
Transcripts:ENSRNOT00000034429
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303585Bw86Body weight QTL 864body mass (VT:0001259)body weight (CMO:0000012)41564430960644309Rat
5685012Bmd87Bone mineral density QTL 875.1tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)43511329080113290Rat
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)439431983123203361Rat
1549843Bw53Body weight QTL 530.0001body mass (VT:0001259)body weight gain (CMO:0000420)459753119104753119Rat
61445Strs3Sensitivity to stroke QTL 33cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)44140057786400577Rat
6893678Bw108Body weight QTL 1082.60.006body mass (VT:0001259)body weight (CMO:0000012)44442502489425024Rat
5685009Bmd86Bone mineral density QTL 863.7tibia mineral mass (VT:1000283)bone mineral density (CMO:0001226)457613242102613242Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)427730518170099664Rat
1331807Rf31Renal function QTL 312.988urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)44049044275726188Rat
634311Sach7Saccharin preference QTL 7taste sensitivity trait (VT:0001986)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)45807987582597589Rat
1358363Sradr3Stress Responsive Adrenal Weight QTL 36.19adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)458817672103817672Rat
61330Eau1Experimental allergic uveoretinitis QTL 10.0003uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)426234499134199155Rat
631261Tcas3Tongue tumor susceptibility QTL 36.88tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)41170660492690519Rat
61336Bp21Blood pressure QTL 214.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)45808014680212111Rat
2313401Anxrr27Anxiety related response QTL 27aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)41890069763900697Rat
2312569Pur19Proteinuria QTL 193.40.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)459836842104836842Rat
8655961Kidm43Kidney mass QTL 4318kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)43726957782269577Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)445429897149763204Rat
6909128Pancm4Pancreatic morphology QTL 411.35pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)427862204126119996Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45889999148002343Rat
61475Aia2Adjuvant induced arthritis QTL 25.8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)44047145375939996Rat
8694439Bw168Body weight QTL 1689.570.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)44140060386400603Rat
61412Pia2Pristane induced arthritis QTL 23.9joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)42228845363245191Rat
8552807Vie4Viral induced encephalitis QTL 47.3brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)41890069763900697Rat
8655906Rf60Renal function QTL 603.8blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)43044896182336920Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)445429709157555683Rat
7387227Uae40Urinary albumin excretion QTL 402.90.0052urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)41891315163913151Rat
6909122Insul22Insulin level QTL 224.63blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)42786220462997402Rat
1558651Swd3Spike wave discharge measurement QTL 34.620.000024brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge frequency (CMO:0001742)44140057786400577Rat
1358203Stl19Serum triglyceride level QTL 192.80.002blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)42192515166925151Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)445429897149763204Rat
1641833Alc21Alcohol consumption QTL 218.60.0001drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)457664252127749483Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)4163900697Rat
1298082Stresp4Stress response QTL 4blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)451085655113588029Rat
631546Bp86Blood pressure QTL 863.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)45807987592690793Rat
1300139Hrtrt6Heart rate QTL 62.85heart pumping trait (VT:2000009)heart rate (CMO:0000002)440490442117737312Rat
70200Alc18Alcohol consumption QTL 189.2drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)457613339151163960Rat
12798520Anxrr55Anxiety related response QTL 554.450.01locomotor behavior trait (VT:0001392)number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)433538597116185060Rat
4889969Bss96Bone structure and strength QTL 964.9tibia size trait (VT:0100001)tibia cortical bone volume (CMO:0001725)457613242102613242Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)412212457182430611Rat
4889972Bss97Bone structure and strength QTL 975.6tibia size trait (VT:0100001)tibia total bone volume (CMO:0001724)457613242102613242Rat
631671Iddm11Insulin dependent diabetes mellitus QTL 113.60.0012blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)45960331980216952Rat

Markers in Region
BE102215  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2459,024,194 - 59,024,402 (+)MAPPERmRatBN7.2
Rnor_6.0457,718,880 - 57,719,087NCBIRnor6.0
Rnor_5.0457,480,505 - 57,480,712UniSTSRnor5.0
RGSC_v3.4457,315,106 - 57,315,313UniSTSRGSC3.4
Celera454,123,396 - 54,123,603UniSTS
RH 3.4 Map4322.2UniSTS
Cytogenetic Map4q22UniSTS
RH133231  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2459,056,601 - 59,056,798 (+)MAPPERmRatBN7.2
Rnor_6.0457,751,286 - 57,751,482NCBIRnor6.0
Rnor_5.0457,512,778 - 57,512,974UniSTSRnor5.0
RGSC_v3.4457,347,545 - 57,347,741UniSTSRGSC3.4
Celera454,155,687 - 54,155,883UniSTS
RH 3.4 Map4325.81UniSTS
Cytogenetic Map4q22UniSTS
BM389047  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2459,061,007 - 59,061,225 (+)MAPPERmRatBN7.2
Rnor_6.0457,755,690 - 57,755,907NCBIRnor6.0
Rnor_5.0457,516,911 - 57,517,128UniSTSRnor5.0
RGSC_v3.4457,351,989 - 57,352,206UniSTSRGSC3.4
Celera454,160,090 - 54,160,307UniSTS
RH 3.4 Map4349.8UniSTS
Cytogenetic Map4q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 92 59 6 356 192 11 143 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000034429   ⟹   ENSRNOP00000038586
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl459,988,771 - 60,042,346 (+)Ensembl
mRatBN7.2 Ensembl459,021,362 - 59,074,941 (+)Ensembl
Rnor_6.0 Ensembl457,716,048 - 57,769,623 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000079059   ⟹   ENSRNOP00000075612
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl459,021,310 - 59,074,941 (+)Ensembl
Rnor_6.0 Ensembl457,715,946 - 57,773,823 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000096895   ⟹   ENSRNOP00000106559
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl459,988,646 - 60,046,516 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000114615   ⟹   ENSRNOP00000081161
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl459,062,649 - 59,074,941 (+)Ensembl
RefSeq Acc Id: NM_001017456   ⟹   NP_001017456
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8459,988,771 - 60,042,346 (+)NCBI
mRatBN7.2459,021,362 - 59,074,941 (+)NCBI
Rnor_6.0457,716,048 - 57,769,623 (+)NCBI
Rnor_5.0457,477,620 - 57,535,303 (+)NCBI
RGSC_v3.4457,312,274 - 57,365,922 (+)RGD
Celera454,120,564 - 54,174,023 (+)RGD
Sequence:
RefSeq Acc Id: XM_006236201   ⟹   XP_006236263
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8459,988,710 - 60,046,518 (+)NCBI
mRatBN7.2459,021,302 - 59,079,118 (+)NCBI
Rnor_6.0457,715,982 - 57,773,800 (+)NCBI
Rnor_5.0457,477,620 - 57,535,303 (+)NCBI
Sequence:
RefSeq Acc Id: NP_001017456   ⟸   NM_001017456
- UniProtKB: Q5U3Y0 (UniProtKB/Swiss-Prot),   A6IEG0 (UniProtKB/TrEMBL),   A0A8I5ZRC5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006236263   ⟸   XM_006236201
- Peptide Label: isoform X1
- UniProtKB: A0A0G2KB15 (UniProtKB/TrEMBL),   A0A8I5ZRC5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000075612   ⟸   ENSRNOT00000079059
Ensembl Acc Id: ENSRNOP00000038586   ⟸   ENSRNOT00000034429
Ensembl Acc Id: ENSRNOP00000081161   ⟸   ENSRNOT00000114615
Ensembl Acc Id: ENSRNOP00000106559   ⟸   ENSRNOT00000096895

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5U3Y0-F1-model_v2 AlphaFold Q5U3Y0 1-410 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692939
Promoter ID:EPDNEW_R3458
Type:initiation region
Name:Klhdc10_1
Description:kelch domain containing 10
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0457,716,024 - 57,716,084EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309792 AgrOrtholog
BioCyc Gene G2FUF-45356 BioCyc
Ensembl Genes ENSRNOG00000010267 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000034429 ENTREZGENE
  ENSRNOT00000034429.5 UniProtKB/Swiss-Prot
  ENSRNOT00000096895 ENTREZGENE
Gene3D-CATH 2.120.10.80 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7115168 IMAGE-MGC_LOAD
InterPro Gal_Oxase/kelch_b-propeller UniProtKB/Swiss-Prot
  Kelch-typ_b-propeller UniProtKB/Swiss-Prot
  Kelch_1 UniProtKB/Swiss-Prot
  KLHDC10 UniProtKB/Swiss-Prot
KEGG Report rno:312199 UniProtKB/Swiss-Prot
MGC_CLONE MGC:105857 IMAGE-MGC_LOAD
NCBI Gene 312199 ENTREZGENE
PANTHER KELCH DOMAIN-CONTAINING PROTEIN 10 UniProtKB/Swiss-Prot
  KELCH DOMAIN-CONTAINING PROTEIN 10 UniProtKB/Swiss-Prot
Pfam Kelch_4 UniProtKB/Swiss-Prot
  Kelch_KLHDC2_KLHL20_DRC7 UniProtKB/Swiss-Prot
PhenoGen Klhdc10 PhenoGen
RatGTEx ENSRNOG00000010267 RatGTEx
SMART Kelch UniProtKB/Swiss-Prot
Superfamily-SCOP SSF117281 UniProtKB/Swiss-Prot
  SSF50965 UniProtKB/Swiss-Prot
UniProt A0A0G2KB15 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZRC5 ENTREZGENE, UniProtKB/TrEMBL
  A6IEG0 ENTREZGENE, UniProtKB/TrEMBL
  KLD10_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-09-09 Klhdc10  kelch domain containing 10  RGD1309792  similar to scruin like at the midline CG5186-PA  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 RGD1309792  similar to scruin like at the midline CG5186-PA  RGD1309792_predicted  similar to scruin like at the midline CG5186-PA (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1309792_predicted  similar to scruin like at the midline CG5186-PA (predicted)  LOC312199_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC312199_predicted  similar to scruin like at the midline CG5186-PA (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL