Jun (Jun proto-oncogene, AP-1 transcription factor subunit) - Rat Genome Database

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Gene: Jun (Jun proto-oncogene, AP-1 transcription factor subunit) Rattus norvegicus
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Symbol: Jun
Name: Jun proto-oncogene, AP-1 transcription factor subunit
RGD ID: 2943
Description: Enables several functions, including DNA binding activity; DNA-binding transcription activator activity, RNA polymerase II-specific; and HMG box domain binding activity. Involved in several processes, including cellular response to potassium ion starvation; positive regulation of apoptotic process; and positive regulation of nucleobase-containing compound metabolic process. Located in chromatin. Part of protein-containing complex. Used to study hypertension. Biomarker of depressive disorder and renal carcinoma. Human ortholog(s) of this gene implicated in pulmonary tuberculosis. Orthologous to human JUN (Jun proto-oncogene, AP-1 transcription factor subunit); PARTICIPATES IN Rho/Rac/Cdc42 mediated signaling pathway; adenosine signaling pathway; endothelin signaling pathway; INTERACTS WITH (+)-pilocarpine; (-)-anisomycin; (R)-lipoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: activator protein 1; AP1; Avian sarcoma virus 17 (v-jun) oncogene homolog; Jun oncogene; jun proto-oncogene; proto-oncogene c-jun; transcription factor AP-1; transcription factor AP-1 subunit Jun; transcription factor Jun; V-jun avian sarcoma virus 17 oncogene homolog; v-jun sarcoma virus 17 oncogene homolog; v-jun sarcoma virus 17 oncogene homolog (avian)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Candidate Gene For: Ciaa5
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85115,009,900 - 115,012,993 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5114,973,151 - 115,013,285 (-)EnsemblGRCr8
mRatBN7.25109,894,175 - 109,897,268 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5109,893,145 - 109,897,656 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5112,464,752 - 112,467,841 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05114,190,270 - 114,193,359 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05114,252,804 - 114,255,893 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05114,011,184 - 114,014,277 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5114,011,189 - 114,014,277 (-)Ensemblrn6Rnor6.0
Rnor_5.05117,957,730 - 117,960,823 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45115,358,166 - 115,361,259 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5108,510,040 - 108,513,133 (-)NCBICelera
RGSC_v3.15115,363,396 - 115,365,980 (-)NCBI
Cytogenetic Map5q33NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(+)-pilocarpine  (EXP)
(+)-Pimaric acid  (ISO)
(+)-taxifolin  (ISO)
(+)-Tetrandrine  (ISO)
(-)-alpha-phellandrene  (ISO)
(-)-anisomycin  (EXP,ISO)
(-)-citrinin  (ISO)
(-)-demecolcine  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(-)-selegiline  (ISO)
(20R)-protopanaxadiol  (ISO)
(20S)-ginsenoside Rh1  (ISO)
(R)-lipoic acid  (EXP)
(R)-noradrenaline  (EXP)
(R,R,R)-alpha-tocopherol  (ISO)
(S)-amphetamine  (EXP,ISO)
(S)-colchicine  (EXP,ISO)
(S)-naringenin  (ISO)
(S)-nicotine  (EXP,ISO)
(Z)-ligustilide  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (EXP,ISO)
1,2,4-trimethylbenzene  (EXP)
1,2-dichlorobenzene  (EXP)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1,4-dichlorobenzene  (EXP)
1,4-dithiothreitol  (ISO)
1-(5-isoquinolinesulfonyl)-2-methylpiperazine  (EXP,ISO)
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile  (EXP)
1-chloro-2,4,6-trinitrobenzene  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
1-naphthyl isothiocyanate  (EXP,ISO)
1-nitropyrene  (ISO)
15-deoxy-Delta(12,14)-prostaglandin J2  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
2,4-diaminotoluene  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-acetamidofluorene  (EXP)
2-amino-2-deoxy-D-glucopyranose  (ISO)
2-aminobiphenyl  (ISO)
2-butoxyethanol  (ISO)
2-hydroxypropanoic acid  (ISO)
2-methylcholine  (ISO)
2-palmitoylglycerol  (ISO)
3',5'-cyclic AMP  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,4-Methylenedioxyamphetamine  (EXP)
3,4-methylenedioxymethamphetamine  (EXP)
3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione  (EXP,ISO)
3-aminobenzamide  (ISO)
3-Methoxynobiletin  (ISO)
3-methyl-3H-imidazo[4,5-f]quinolin-2-amine  (ISO)
3-methylcholanthrene  (ISO)
3-phenylprop-2-enal  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (ISO)
4-aminobenzohydrazide  (ISO)
4-hydroxy-TEMPO  (ISO)
4-hydroxybenzoic acid  (ISO)
4-hydroxynon-2-enal  (EXP,ISO)
4-hydroxyphenyl retinamide  (ISO)
4-nitroquinoline N-oxide  (ISO)
4-tert-Octylphenol  (ISO)
4-vinylcyclohexene dioxide  (ISO)
5,6,7-trimethoxyflavone  (ISO)
5-(2-methylpiperazine-1-sulfonyl)isoquinoline  (EXP,ISO)
5-aza-2'-deoxycytidine  (ISO)
5-bromo-2'-deoxyuridine  (ISO)
5-chloro-7-iodoquinolin-8-ol  (ISO)
5-fluorouracil  (ISO)
5-Nitro-2-(3-phenylpropylamino)benzoic acid  (ISO)
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide  (ISO)
6-propyl-2-thiouracil  (EXP)
7,12-dimethyltetraphene  (EXP,ISO)
7H-xanthine  (EXP)
8-Br-cAMP  (ISO)
9-cis-retinoic acid  (ISO)
9-Methoxycamptothecin  (ISO)
9H-xanthine  (EXP)
acetaldehyde  (EXP,ISO)
acetamide  (EXP)
acetylleucyl-leucyl-norleucinal  (ISO)
acetylsalicylic acid  (ISO)
acrolein  (EXP,ISO)
acrylamide  (ISO)
acrylonitrile  (ISO)
actinomycin D  (EXP,ISO)
afimoxifene  (ISO)
aflatoxin B1  (EXP,ISO)
AH23848  (ISO)
alcohol  (ISO)
aldehydo-D-glucosamine  (ISO)
aldehydo-D-glucose  (EXP,ISO)
all-trans-retinoic acid  (EXP,ISO)
alpha-Chaconine  (ISO)
alpha-D-galactose  (ISO)
alpha-naphthoflavone  (EXP,ISO)
alpha-phellandrene  (ISO)
alpha-pinene  (ISO)
aluminium atom  (ISO)
aluminium oxide  (ISO)
aluminium(0)  (ISO)
alvocidib  (ISO)
amiodarone  (EXP,ISO)
ammonium chloride  (EXP)
amphetamine  (EXP,ISO)
andrographolide  (ISO)
aniline  (EXP)
anthra[1,9-cd]pyrazol-6(2H)-one  (EXP,ISO)
antimycin A  (ISO)
antirheumatic drug  (ISO)
antroquinonol  (ISO)
AP20187  (ISO)
Apicularen A  (ISO)
apigenin  (ISO)
apocynin  (ISO)
apomorphine  (ISO)
arachidonic acid  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (EXP,ISO)
asbestos  (ISO)
asoxime chloride  (EXP)
atazanavir sulfate  (ISO)
atorvastatin calcium  (ISO)
ATP  (ISO)
atrazine  (EXP,ISO)
atropine  (EXP)
auraptene  (ISO)
Azaspiracid  (ISO)
azathioprine  (ISO)
bacitracin  (EXP)
baicalein  (ISO)
bathocuproine disulfonic acid  (ISO)
Bay-K-8644  (ISO)
benzene  (ISO)
benzene-1,2,4-triol  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
Benzo[k]fluoranthene  (ISO)
benzofurans  (ISO)
benzophenanthridine  (ISO)
Benzoyl peroxide  (ISO)
benzyl isothiocyanate  (ISO)
benzylpenicillin  (ISO)
berberine  (EXP)
beryllium sulfate  (ISO)
beta-carotene  (ISO)
beta-cyclodextrin  (ISO)
beta-D-glucosamine  (ISO)
beta-hexachlorocyclohexane  (EXP)
beta-lapachone  (ISO)
beta-naphthoflavone  (ISO)
bezafibrate  (ISO)
bis(2-chloroethyl) sulfide  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (EXP)
bleomycin A2  (ISO)
bortezomib  (EXP,ISO)
bromodichloromethane  (EXP)
bucladesine  (ISO)
budesonide  (EXP)
bufalin  (ISO)
buspirone  (EXP)
butanal  (ISO)
butylated hydroxyanisole  (ISO)
Butylbenzyl phthalate  (EXP,ISO)
butyric acid  (ISO)
C.I. Natural Red 20  (ISO)
cadmium acetate  (EXP)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
cadmium sulfate  (ISO)
caffeine  (ISO)
Calcimycin  (ISO)
calcitriol  (ISO)
Calphostin C  (EXP)
camostat  (ISO)
camptothecin  (EXP,ISO)
cannabidiol  (ISO)
Cannabinol  (ISO)
cantharidin  (ISO)
capsaicin  (EXP,ISO)
captan  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
carboplatin  (EXP)
Carnosol  (EXP)
cefaloridine  (EXP)
celastrol  (EXP,ISO)
celecoxib  (ISO)
cerium trichloride  (ISO)
ceruletide  (ISO)
CGP 52608  (ISO)
chenodeoxycholic acid  (ISO)
chloramphenicol  (ISO)
chlorogenic acid  (ISO)
chloropicrin  (ISO)
chloroprene  (EXP)
chlorpyrifos  (ISO)
choline  (ISO)
chromium atom  (ISO)
chromium trioxide  (ISO)
chromium(6+)  (EXP,ISO)
chrysene  (ISO)
chrysin  (ISO)
ciglitazone  (EXP,ISO)
Cinobufagin  (ISO)
Cinobufotalin  (ISO)
ciprofibrate  (ISO)
cisplatin  (EXP,ISO)
citalopram  (EXP)
clofibrate  (EXP,ISO)
clofibric acid  (EXP)
clozapine  (EXP)
cobalt atom  (ISO)
cocaine  (EXP,ISO)
colforsin daropate hydrochloride  (EXP)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
cordycepin  (ISO)
corn oil  (ISO)
corosolic acid  (ISO)
corticosterone  (EXP)
coumestrol  (ISO)
crocidolite asbestos  (EXP,ISO)
CU-O LINKAGE  (ISO)
cudratricusxanthone A  (ISO)
curcumin  (EXP,ISO)
cycloheximide  (EXP,ISO)
cyclosporin A  (EXP,ISO)
cylindrospermopsin  (ISO)
cypermethrin  (EXP,ISO)
cytarabine  (ISO)
D-glucitol  (ISO)
D-glucose  (EXP,ISO)
D-mannitol  (EXP)
daidzein  (ISO)
DDE  (EXP,ISO)
DDT  (ISO)
deguelin  (ISO)
dehydroepiandrosterone  (ISO)
delphinidin  (ISO)
delta-tocotrienol  (ISO)
deoxycholic acid  (ISO)
Deoxycorticosterone acetate  (EXP)
deoxynivalenol  (ISO)
desferrioxamine B  (ISO)
Destruxin B  (ISO)
dexamethasone  (EXP,ISO)
dextran sulfate  (ISO)
dextromethorphan  (EXP,ISO)
diallyl disulfide  (ISO)
Diallyl sulfide  (EXP)
diallyl trisulfide  (EXP,ISO)
Diallyltetrasulfane  (EXP)
diamminedichloroplatinum  (ISO)
diarsenic trioxide  (EXP,ISO)
diazepam  (EXP)
diazinon  (EXP)
dibenziodolium  (ISO)
dibenzofuran  (EXP)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP,ISO)
dichlorine  (EXP)
dichloroacetic acid  (ISO)
dichloromethane  (ISO)
diclofenac  (ISO)
dicoumarol  (ISO)
Dictamnine  (ISO)
dieckol  (ISO)
dieldrin  (EXP,ISO)
diethyl maleate  (ISO)
diethylstilbestrol  (ISO)
dihydroartemisinin  (ISO)
dihydrolipoic acid  (EXP)
diiodine  (EXP)
Dimaprit  (ISO)
dimemorfan  (EXP,ISO)
dimethyl sulfoxide  (EXP,ISO)
dimethylarsinic acid  (ISO)
dinophysistoxin 1  (ISO)
dioxygen  (ISO)
diquat  (ISO)
disodium selenite  (EXP,ISO)
disulfiram  (ISO)
divanadium pentaoxide  (ISO)
dizocilpine maleate  (EXP)
dobutamine  (EXP)
donepezil hydrochloride  (ISO)
dopamine  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
efavirenz  (ISO)
elemental selenium  (EXP,ISO)
ellagic acid  (ISO)
endosulfan  (ISO)
enilconazole  (ISO)
Enterolactone  (ISO)
enzyme inhibitor  (ISO)
epoxiconazole  (ISO)
Erionite  (EXP)
erythrosin B  (ISO)
escitalopram  (EXP)
estra-1,3,5(10)-triene-3,16beta-diol  (EXP)
estriol  (EXP)
etacrynic acid  (ISO)
ethanol  (EXP,ISO)
ethyl methanesulfonate  (ISO)
ethylene glycol bis(2-aminoethyl)tetraacetic acid  (ISO)
etoposide  (ISO)
etoxazole  (ISO)
fenofibrate  (ISO)
fenthion  (ISO)
fentin chloride  (EXP)
ferric oxide  (EXP)
ferrosoferric oxide  (ISO)
ferulic acid  (ISO)
fisetin  (ISO)
Flavokawain A  (ISO)
flavonol  (ISO)
flufenoxuron  (ISO)
flumequine  (ISO)
fluoranthene  (ISO)
fluoxetine  (ISO)
flutamide  (EXP)
folic acid  (ISO)
folpet  (ISO)
formaldehyde  (ISO)
formononetin  (ISO)
fotemustine  (ISO)
fructose  (EXP)
fulvestrant  (ISO)
furan  (EXP,ISO)
galactose  (ISO)
gallic acid  (ISO)
gamma-aminobutyric acid  (EXP)
gamma-hexachlorocyclohexane  (EXP,ISO)
gamma-tocopherol  (ISO)
gemcitabine  (ISO)
Geniposide pentaacetate  (EXP)
genistein  (ISO)
gentamycin  (EXP)
geraniol  (ISO)
gingerol  (ISO)
glucaric acid  (ISO)
glucose  (EXP,ISO)
glutathione  (ISO)
glycidol  (EXP)
glycine betaine  (EXP)
glycitein  (ISO)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
glyphosate  (ISO)
Goe 6976  (ISO)
gold atom  (ISO)
gold(0)  (ISO)
gossypin  (ISO)
GSK-J4  (ISO)
haloperidol  (EXP)
hemin  (EXP,ISO)
heparin  (ISO)
heptachlor  (ISO)
herbimycin  (ISO)
hexachlorobenzene  (EXP)
hexadecanoic acid  (ISO)
hyaluronic acid  (ISO)
hydrogen cyanide  (ISO)
hydrogen peroxide  (EXP,ISO)
hydrogen sulfide  (ISO)
hydroquinone  (ISO)
hydroquinone O-beta-D-glucopyranoside  (ISO)
hydroxychloroquine  (ISO)
hydroxytyrosol  (EXP,ISO)
hyperforin  (ISO)
icariin  (ISO)
Indeno[1,2,3-cd]pyrene  (ISO)
indole-3-methanol  (EXP,ISO)
indometacin  (EXP,ISO)
indoxyl sulfate  (ISO)
inulin  (ISO)
ionomycin  (ISO)
irinotecan  (EXP,ISO)
iron atom  (ISO)
iron dichloride  (ISO)
iron trichloride  (ISO)
iron(0)  (ISO)
iron(2+) sulfate (anhydrous)  (ISO)
iron(III) nitrilotriacetate  (EXP)
isoflavones  (ISO)
isoflurane  (EXP)
isoprenaline  (EXP,ISO)
isorhapontigenin  (EXP)
kaempferol  (ISO)
kainic acid  (EXP)
kanamycin A  (EXP)
ketamine  (EXP)
kojic acid  (ISO)
KT 5720  (ISO)
L-1,4-dithiothreitol  (ISO)
L-methionine  (ISO)
L-serine  (ISO)
lanthanum atom  (EXP)
lanthanum trichloride  (EXP)
lead diacetate  (ISO)
lead(0)  (EXP,ISO)
leflunomide  (ISO)
Licochalcone B  (ISO)
limonene  (ISO)
linalool  (ISO)
lipoic acid  (EXP)
lipopolysaccharide  (EXP,ISO)
lipoteichoic acid  (ISO)
lithium atom  (EXP)
lithium chloride  (ISO)
lithium hydride  (EXP)
lithocholic acid  (ISO)
losartan  (EXP)
lovastatin  (EXP,ISO)
luteolin  (EXP,ISO)
LY294002  (EXP,ISO)
lycopene  (ISO)
Maduramicin  (EXP,ISO)
maneb  (EXP)
manganese atom  (EXP,ISO)
manganese(0)  (EXP,ISO)
manganese(II) chloride  (EXP)
maslinic acid  (ISO)
masoprocol  (ISO)
Mecamylamine  (EXP)
mechlorethamine  (ISO)
MeIQx  (ISO)
melatonin  (EXP)
melittin  (ISO)
menadione  (ISO)
mercury atom  (EXP,ISO)
mercury dibromide  (ISO)
mercury dichloride  (EXP,ISO)
mercury(0)  (EXP,ISO)
mesalamine  (ISO)
metacetamol  (ISO)
metformin  (ISO)
methamphetamine  (EXP,ISO)
methapyrilene  (EXP)
methohexital  (ISO)
methotrexate  (EXP,ISO)
methyl methanesulfonate  (ISO)
methylarsonic acid  (ISO)
methylisothiazolinone  (ISO)
methylmercury chloride  (EXP,ISO)
methylseleninic acid  (ISO)
methyltestosterone  (ISO)
metoprolol  (EXP)
metyrapone  (EXP)
mevinphos  (EXP)
Mezerein  (ISO)
mibolerone  (ISO)
microcystin-LR  (ISO)
minocycline  (ISO)
miquelianin  (ISO)
mitoxantrone  (ISO)
ML-7  (EXP)
mono(2-ethylhexyl) phthalate  (EXP,ISO)
Monobutylphthalate  (ISO)
monocrotophos  (EXP,ISO)
morin  (EXP)
morphine  (ISO)
morusin  (ISO)
Muconic dialdehyde  (ISO)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (ISO)
N-(6-acetamidohexyl)acetamide  (ISO)
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide  (EXP,ISO)
N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-(2-pyridinyl)cyclohexanecarboxamide  (EXP)
N-acetyl-L-cysteine  (EXP,ISO)
N-acetylsphingosine  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-ethyl-N-nitrosourea  (ISO)
N-feruloyltyramine  (ISO)
N-methyl-4-phenylpyridinium  (EXP,ISO)
N-methyl-N-nitrosourea  (EXP)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (EXP)
N-nitrosomorpholine  (EXP)
N-Nitrosopyrrolidine  (ISO)
N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine  (EXP)
naphthalene  (ISO)
naringin  (ISO)
nectandrin B  (ISO)
nefazodone  (EXP,ISO)
neocuproine  (EXP)
neohesperidin  (ISO)
neomycin  (EXP,ISO)
nevirapine  (ISO)
nickel atom  (ISO)
nickel dichloride  (EXP,ISO)
nickel subsulfide  (ISO)
nickel sulfate  (ISO)
niclosamide  (EXP,ISO)
nicotinamide  (EXP)
nicotine  (EXP,ISO)
nilotinib  (ISO)
nimodipine  (EXP)
nimustine  (ISO)
nitric oxide  (EXP)
nitrofurantoin  (EXP)
nitrofurazone  (EXP)
nitrogen dioxide  (EXP)
nitroprusside  (EXP)
nocodazole  (ISO)
Nodularin  (ISO)
Nonylphenol  (ISO)
Nor-9-carboxy-delta9-THC  (ISO)
NSC 23766  (ISO)
obeticholic acid  (ISO)
ochratoxin A  (EXP,ISO)
okadaic acid  (ISO)
olmesartan  (ISO)
oltipraz  (ISO)
omipalisib  (ISO)
organoselenium compound  (ISO)
orphenadrine  (EXP)
ouabain  (ISO)
oxaliplatin  (EXP,ISO)
oxamic acid  (ISO)
oxidopamine  (ISO)
oxybutynin  (EXP)
ozone  (EXP,ISO)
p-chloromercuribenzoic acid  (ISO)
p-cresol  (ISO)
p-menthan-3-ol  (ISO)
p-tert-Amylphenol  (ISO)
paclitaxel  (EXP,ISO)
palytoxin  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
paraoxon  (ISO)
paraquat  (EXP,ISO)
patulin  (EXP,ISO)
PD 0325901  (EXP)
pent-4-enoic acid  (EXP)
pentobarbital  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (ISO)
perindopril  (EXP)
permethrin  (EXP)
pevonedistat  (ISO)
phenethyl caffeate  (ISO)
phenformin  (EXP)
phenobarbital  (EXP,ISO)
phenylarsine oxide  (ISO)
phenylephrine  (EXP,ISO)
phenylmercury acetate  (ISO)
phenytoin  (ISO)
PhIP  (EXP)
phorbol 12,13-dibutanoate  (EXP)
phorbol 13-acetate 12-myristate  (EXP,ISO)
phorone  (EXP)
phosphane  (EXP)
phylloquinone  (ISO)
physostigmine  (EXP)
pifithrin-alpha hydrobromide  (ISO)
piperine  (ISO)
piperonyl butoxide  (ISO)
pipoxolan  (ISO)
pirfenidone  (ISO)
pirinixic acid  (ISO)
potassium atom  (EXP)
potassium cyanide  (ISO)
potassium dichromate  (ISO)
prazosin  (EXP)
prednisolone  (EXP)
prednisone  (EXP)
pregnenolone 16alpha-carbonitrile  (EXP,ISO)
prodigiosin  (ISO)
progesterone  (EXP,ISO)
propan-2-ol  (ISO)
propofol  (EXP)
prostaglandin J2  (ISO)
protein kinase inhibitor  (EXP)
pterostilbene  (ISO)
Pulsatilla saponin D  (ISO)
pyridine  (EXP)
pyrrolidine dithiocarbamate  (ISO)
quartz  (ISO)
quercetin  (EXP,ISO)
quinolin-8-ol  (ISO)
rac-lactic acid  (ISO)
raloxifene  (ISO)
ranitidine  (EXP)
razoxane  (ISO)
reactive oxygen species  (ISO)
Rebamipide  (EXP)
reserpine  (EXP)
resveratrol  (EXP,ISO)
rifampicin  (ISO)
Riluzole  (EXP)
ritonavir  (ISO)
Ro 31-8220  (EXP,ISO)
ropinirole  (ISO)
rosmarinic acid  (EXP)
rotenone  (EXP,ISO)
rottlerin  (ISO)
rutin  (ISO)
ruxolitinib  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (EXP,ISO)
saccharin  (ISO)
SB 203580  (EXP,ISO)
SB 431542  (ISO)
SCH772984  (EXP)
sclareol  (ISO)
scoparone  (ISO)
scopolamine  (EXP,ISO)
scutellarin  (ISO)
Se-methyl-L-selenocysteine  (EXP)
Se-methylselenocysteine  (EXP)
secobarbital  (ISO)
selenium atom  (EXP,ISO)
serpentine asbestos  (EXP,ISO)
sertraline  (ISO)
Shikonin  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
simvastatin  (EXP,ISO)
sirolimus  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (EXP,ISO)
sodium benzoate  (ISO)
sodium chloride  (EXP)
sodium dichromate  (ISO)
sodium fluoride  (EXP)
sodium hydroxide  (EXP)
sodium lactate  (ISO)
Sodium salicylate  (EXP)
Soman  (EXP)
sorafenib  (ISO)
staurosporine  (EXP)
stavudine  (EXP)
streptozocin  (EXP,ISO)
styrene  (ISO)
sulfadimethoxine  (ISO)
sulforaphane  (EXP)
sulfur dioxide  (EXP)
sulindac  (ISO)
sulindac sulfide  (ISO)
Sunset Yellow FCF  (ISO)
superoxide  (EXP,ISO)
T-2 toxin  (EXP,ISO)
tacrolimus hydrate  (EXP)
tamoxifen  (EXP,ISO)
tartrazine  (ISO)
taurine  (EXP)
taurolithocholic acid  (ISO)
tauroursodeoxycholic acid  (ISO)
tebufenpyrad  (ISO)
terbufos  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (EXP,ISO)
tetramethylpyrazine  (EXP,ISO)
tetraphene  (ISO)
tetrodotoxin  (EXP)
thalidomide  (ISO)
thapsigargin  (ISO)
Theaflavin 3,3'-digallate  (ISO)
thiamylal  (ISO)
thimerosal  (ISO)
thioacetamide  (EXP)
thiopental  (ISO)
thiourea  (ISO)
thiram  (ISO)
Tiron  (ISO)
titanium dioxide  (ISO)
tocopherol  (ISO)
tofacitinib  (ISO)
topotecan  (EXP,ISO)
torcetrapib  (ISO)
trametinib  (ISO)
transplatin  (ISO)
triacsin C  (ISO)
tributylstannane  (ISO)
Tributyltin oxide  (ISO)
trichloroacetic acid  (ISO)
trichloroethene  (EXP,ISO)
trichostatin A  (ISO)
triclosan  (ISO)
trimethyltin  (ISO)
trioxsalen  (ISO)
triphenyl phosphate  (ISO)
Triptolide  (ISO)
troglitazone  (ISO)
tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate  (EXP)
tungsten  (ISO)
Tungsten carbide  (ISO)
tunicamycin  (ISO)
tyrphostin AG 1478  (EXP,ISO)
U-73122  (EXP)
undecane  (EXP)
urethane  (ISO)
Urolithin A  (ISO)
ursolic acid  (ISO)
valproic acid  (EXP,ISO)
valsartan  (EXP)
vanadyl sulfate  (ISO)
vancomycin  (EXP)
Vernodalin  (ISO)
vincaleukoblastine  (ISO)
vinclozolin  (EXP)
vincristine  (ISO)
vitamin D  (EXP,ISO)
vitamin E  (ISO)
vorinostat  (ISO)
wedelolactone  (ISO)
wogonin  (ISO)
xanthones  (ISO)
XMU-MP-1  (ISO)
zearalenone  (ISO)
zinc atom  (EXP,ISO)
zinc dichloride  (ISO)
zinc oxide  (ISO)
zinc protoporphyrin  (ISO)
zinc sulfate  (ISO)
zinc(0)  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
angiogenesis  (IMP,ISO)
axon regeneration  (ISO)
cellular response to anisomycin  (IEA,ISO)
cellular response to calcium ion  (ISO)
cellular response to hypoxia  (IEA,IEP)
cellular response to lipopolysaccharide  (ISO)
cellular response to potassium ion starvation  (IMP)
cellular response to prolactin  (IEP)
cellular response to zinc ion starvation  (IEP)
circadian rhythm  (IEP)
DNA-templated transcription  (IDA)
eyelid development in camera-type eye  (ISO)
immune response  (ISO)
JNK cascade  (IEA,ISO)
leading edge cell differentiation  (ISO)
learning  (IMP)
liver development  (ISO)
membrane depolarization  (IDA)
microglial cell activation  (ISO)
monocyte differentiation  (ISO)
negative regulation of apoptotic process  (ISO)
negative regulation of cell population proliferation  (ISO)
negative regulation of DNA-templated transcription  (ISO)
negative regulation of neuron apoptotic process  (ISO)
negative regulation of protein autophosphorylation  (ISO)
negative regulation of transcription by RNA polymerase II  (ISO)
outflow tract morphogenesis  (ISO)
positive regulation of apoptotic process  (IMP)
positive regulation of apoptotic signaling pathway  (IMP)
positive regulation of cell population proliferation  (IMP)
positive regulation of DNA replication  (IMP)
positive regulation of DNA-templated transcription  (IDA,ISO)
positive regulation of DNA-templated transcription initiation  (ISO)
positive regulation of endothelial cell proliferation  (ISO)
positive regulation of epithelial cell migration  (ISO)
positive regulation of ERK1 and ERK2 cascade  (ISO)
positive regulation of fibroblast proliferation  (ISO)
positive regulation of miRNA transcription  (IDA,ISO)
positive regulation of monocyte differentiation  (IDA)
positive regulation of neuron apoptotic process  (IMP)
positive regulation of smooth muscle cell proliferation  (IDA)
positive regulation of transcription by RNA polymerase II  (IBA,IDA,IMP,ISO,ISS)
positive regulation of vascular associated smooth muscle cell proliferation  (ISO)
regulation of cell cycle  (IBA,ISO)
regulation of cell population proliferation  (IBA)
regulation of DNA-templated transcription  (IEA,ISO)
regulation of transcription by RNA polymerase II  (ISO)
release from viral latency  (ISO)
release of cytochrome c from mitochondria  (IMP)
response to cAMP  (IEP)
response to cytokine  (IEP)
response to endoplasmic reticulum stress  (ISO)
response to ethanol  (IEP)
response to forskolin  (IEA,IEP)
response to hydrogen peroxide  (IEP)
response to insulin  (IEP)
response to lipopolysaccharide  (IEP)
response to mechanical stimulus  (IEP)
response to muscle stretch  (ISO)
response to steroid hormone  (IBA,IEP)
response to xenobiotic stimulus  (IEP,ISO)
SMAD protein signal transduction  (ISO)
transcription by RNA polymerase II  (IEA,IMP,TAS)
transforming growth factor beta receptor signaling pathway  (ISO)
transforming growth factor beta1 production  (ISO)

Cellular Component

References

References - curated
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19. Inactivation of AP1 proteins by a nuclear serine protease precedes the onset of radiation-induced fibrosing alveolitis. Haase MG, etal., Radiat Res. 2008 May;169(5):531-42.
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29. H(2)O(2)-induced egr-1, fra-1, and c-jun gene expression is mediated by tyrosine kinase in aortic smooth muscle cells. Jin N, etal., Free Radic Biol Med. 2000 Oct 15;29(8):736-46.
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31. Identification of cJun-responsive genes in Rat-1a cells using multiple techniques: increased expression of stathmin is necessary for cJun-mediated anchorage-independent growth. Kinoshita I, etal., Oncogene 2003 May 8;22(18):2710-22.
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34. Chronic antipsychotic drug treatment induces long-lasting expression of fos and jun family genes and activator protein 1 complex in the rat prefrontal cortex. Kontkanen O, etal., Neuropsychopharmacology. 2002 Aug;27(2):152-62.
35. Co-expression of c-Jun and ATF-2 characterizes the surviving retinal ganglion cells which maintain axonal connections after partial optic nerve injury. Kreutz MR, etal., Brain Res Mol Brain Res. 1999 Jun 8;69(2):232-41.
36. Blockade of 12-lipoxygenase expression protects cortical neurons from apoptosis induced by beta-amyloid peptide. Lebeau A, etal., Cell Death Differ. 2004 Aug;11(8):875-84.
37. A dominant negative Egr inhibitor blocks nerve growth factor-induced neurite outgrowth by suppressing c-Jun activation: role of an Egr/c-Jun complex. Levkovitz Y and Baraban JM, J Neurosci. 2002 May 15;22(10):3845-54.
38. Characterization of the chromosomal binding sites and dimerization partners of the viral oncoprotein Meq in Marek's disease virus-transformed T cells. Levy AM, etal., J Virol. 2003 Dec;77(23):12841-51.
39. Oral steroids enhance epithelial repair in nasal polyposis via upregulation of the AP-1 gene network. Li CW, etal., Thorax. 2009 Apr;64(4):306-12. Epub 2009 Jan 21.
40. Differentiation of WEHI-3B D+ myelomonocytic leukemia cells induced by ectopic expression of the protooncogene c-jun. Li J, etal., Cell Growth Differ. 1994 Jul;5(7):743-51.
41. microRNA-149-5p mediates the PM2.5-induced inflammatory response by targeting TAB2 via MAPK and NF-κB signaling pathways in vivo and in vitro. Li Q, etal., Cell Biol Toxicol. 2021 Jul 31. pii: 10.1007/s10565-021-09638-5. doi: 10.1007/s10565-021-09638-5.
42. dp5/HRK is a c-Jun target gene and required for apoptosis induced by potassium deprivation in cerebellar granule neurons. Ma C, etal., J Biol Chem. 2007 Oct 19;282(42):30901-9. Epub 2007 Apr 11.
43. Immunohistochemical detection of RAS, JUN, FOS, and p53 oncoprotein expression in human colorectal adenomas and carcinomas. Magrisso IJ, etal., Lab Invest. 1993 Dec;69(6):674-81.
44. Aberrantly expressed c-Jun and JunB are a hallmark of Hodgkin lymphoma cells, stimulate proliferation and synergize with NF-kappa B. Mathas S, etal., EMBO J 2002 Aug 1;21(15):4104-13.
45. Impaired activation of AP-1 and altered expression of constituent proteins in rat adrenal during ageing. Medicherla R, etal., Mech Ageing Dev. 2001 Aug;122(11):1169-86.
46. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
47. Mechanical stretch and progesterone differentially regulate activator protein-1 transcription factors in primary rat myometrial smooth muscle cells. Mitchell JA, etal., Am J Physiol Endocrinol Metab. 2004 Sep;287(3):E439-45. Epub 2004 May 4.
48. Inducible-NOS but not neuronal-NOS participate in the acute effect of TNF-alpha on hypothalamic insulin-dependent inhibition of food intake. Moraes JC, etal., FEBS Lett. 2006 Aug 21;580(19):4625-31. doi: 10.1016/j.febslet.2006.07.042. Epub 2006 Jul 21.
49. JNK phosphorylates synaptotagmin-4 and enhances Ca2+-evoked release. Mori Y, etal., EMBO J. 2008 Jan 9;27(1):76-87. Epub 2007 Nov 29.
50. Pregnenolone sulfate activates basic region leucine zipper transcription factors in insulinoma cells: role of voltage-gated Ca2+ channels and transient receptor potential melastatin 3 channels. Müller I, etal., Mol Pharmacol. 2011 Dec;80(6):1179-89. doi: 10.1124/mol.111.074781. Epub 2011 Sep 23.
51. c-Jun is regulated by combination of enhanced expression and phosphorylation in acute-overloaded rat heart. Nadruz W Jr, etal., Am J Physiol Heart Circ Physiol 2004 Feb;286(2):H760-7. Epub 2003 Sep 25.
52. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
53. Expression of fos and jun proto-oncogenes in benign versus malignant human uterine tissue. Nephew KP, etal., Gynecol Oncol. 2000 Mar;76(3):388-96.
54. C-jun activation in acquired cystic kidney disease and renal cell carcinoma. Oya M, etal., J Urol 2005 Aug;174(2):726.
55. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
56. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
57. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
58. Cell selective induction and transcriptional activation of immediate early genes by hypoxia. Prabhakar NR, etal., Brain Res. 1995 Oct 30;697(1-2):266-70. doi: 10.1016/0006-8993(95)00994-2.
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60. beta2-Adrenergic receptor regulation by GIT1, a G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein. Premont RT, etal., Proc Natl Acad Sci U S A 1998 Nov 24;95(24):14082-7.
61. GOA pipeline RGD automated data pipeline
62. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
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64. Activity deprivation-dependent induction of the proapoptotic BH3-only protein Bim is independent of JNK/c-Jun activation during apoptosis in cerebellar granule neurons. Shi L, etal., Neurosci Lett. 2005 Feb 25;375(1):7-12. Epub 2004 Nov 24.
65. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
66. Activation of the cAMP pathway synergistically increases IL-1-induced IL-6 gene expression in FRTL-5 thyroid cells: involvement of AP-1 transcription factors. Szabo-Fresnais N, etal., Mol Cell Endocrinol. 2008 Mar 12;284(1-2):28-37. Epub 2008 Jan 8.
67. Expression of c-jun oncogene in hyperplastic and carcinomatous human prostate. Tiniakos DG, etal., Urology. 2006 Jan;67(1):204-8.
68. Sequence-specific impairment of learning by c-jun antisense oligonucleotides. Tischmeyer W, etal., Neuroreport. 1994 Jul 21;5(12):1501-4.
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70. Overexpression of members of the AP-1 transcriptional factor family from an early stage of renal carcinogenesis and inhibition of cell growth by AP-1 gene antisense oligonucleotides in the Tsc2 gene mutant (Eker) rat model. Urakami S, etal., Biochem Biophys Res Commun. 1997 Dec 8;241(1):24-30.
71. Basic fibroblast growth factor stimulates collagenase-3 promoter activity in osteoblasts through an activator protein-1-binding site. Varghese S, etal., Endocrinology. 2000 Jun;141(6):2185-91.
72. Distinct Expression of c-Jun and HSP27 in Axotomized and Spared Bulbospinal Neurons After Cervical Spinal Cord Injury. Vinit S, etal., J Mol Neurosci. 2010 Dec 4.
73. c-Jun activation is associated with proliferation and angiogenesis in invasive breast cancer. Vleugel MM, etal., Hum Pathol. 2006 Jun;37(6):668-74.
74. Integrated microarray analysis provided novel insights to the pathogenesis of glaucoma. Wang J, etal., Mol Med Rep. 2017 Dec;16(6):8735-8746. doi: 10.3892/mmr.2017.7711. Epub 2017 Oct 4.
75. Chronic alcohol intake reduces retinoic acid concentration and enhances AP-1 (c-Jun and c-Fos) expression in rat liver. Wang XD, etal., Hepatology. 1998 Sep;28(3):744-50. doi: 10.1002/hep.510280321.
76. Dominant-negative c-Jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial cytochrome c release. Whitfield J, etal., Neuron. 2001 Mar;29(3):629-43.
77. Sequential increase in Egr-1 and AP-1 DNA binding activity in the dentate gyrus following the induction of long-term potentiation. Williams JM, etal., Brain Res Mol Brain Res. 2000 May 5;77(2):258-66.
78. The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors. Wissmuller S, etal., Nucleic Acids Res. 2006 Mar 31;34(6):1735-44. Print 2006.
79. The differential molecular mechanisms underlying proenkephalin mRNA expression induced by forskolin and phorbol-12-myristic-13-acetate in primary cultured astrocytes. Won JS and Suh HW, Brain Res Mol Brain Res. 2000 Dec 8;84(1-2):41-51.
80. Prolonged c-Jun expression in the basolateral amygdala following bulbectomy: possible implications for antidepressant activity and time of onset. Wrynn AS, etal., Brain Res Mol Brain Res. 2000 Mar 10;76(1):7-17.
81. POSH acts as a scaffold for a multiprotein complex that mediates JNK activation in apoptosis. Xu Z, etal., EMBO J. 2003 Jan 15;22(2):252-61.
82. c-Jun decreases voltage-gated K(+) channel activity in pulmonary artery smooth muscle cells. Yu Y, etal., Circulation. 2001 Sep 25;104(13):1557-63.
83. Opposing roles for ATF2 and c-Fos in c-Jun-mediated neuronal apoptosis. Yuan Z, etal., Mol Cell Biol. 2009 May;29(9):2431-42. doi: 10.1128/MCB.01344-08. Epub 2009 Mar 2.
84. Effect of deoxyribozymes targeting c-Jun on solid tumor growth and angiogenesis in rodents. Zhang G, etal., J Natl Cancer Inst. 2004 May 5;96(9):683-96.
85. 4-Hydroxynonenal induces rat gamma-glutamyl transpeptidase through mitogen-activated protein kinase-mediated electrophile response element/nuclear factor erythroid 2-related factor 2 signaling. Zhang H, etal., Am J Respir Cell Mol Biol. 2006 Feb;34(2):174-81. Epub 2005 Sep 29.
86. Increased expression and activation of c-Jun contributes to human amylin-induced apoptosis in pancreatic islet beta-cells. Zhang S, etal., J Mol Biol 2002 Nov 22;324(2):271-85.
Additional References at PubMed
PMID:1651323   PMID:2833704   PMID:8662824   PMID:8889548   PMID:9098922   PMID:9651196   PMID:9710592   PMID:9732876   PMID:9847304   PMID:10076871   PMID:10352021   PMID:10508860  
PMID:11053448   PMID:11146548   PMID:11804590   PMID:11818961   PMID:11860940   PMID:12050152   PMID:12064606   PMID:12490281   PMID:12791271   PMID:12798298   PMID:12857463   PMID:12869527  
PMID:12943993   PMID:14643899   PMID:14645924   PMID:14739464   PMID:15189336   PMID:15233917   PMID:15489334   PMID:15557322   PMID:15737994   PMID:15797868   PMID:15911351   PMID:16007074  
PMID:16039502   PMID:16087680   PMID:16158334   PMID:16847049   PMID:16874457   PMID:16916642   PMID:17111371   PMID:17182846   PMID:17216194   PMID:17503228   PMID:17504975   PMID:17551755  
PMID:17681951   PMID:17720185   PMID:18024959   PMID:18029144   PMID:18192274   PMID:18314492   PMID:18320311   PMID:18326819   PMID:18485334   PMID:18524853   PMID:18596606   PMID:18646529  
PMID:18782540   PMID:18846332   PMID:18854993   PMID:19041662   PMID:19080378   PMID:19194552   PMID:19225867   PMID:19238548   PMID:19303854   PMID:19404732   PMID:19439112   PMID:19477969  
PMID:19538471   PMID:19628677   PMID:19737467   PMID:19765400   PMID:19861239   PMID:20032511   PMID:20092996   PMID:20096669   PMID:20102225   PMID:20155456   PMID:20170659   PMID:20232736  
PMID:20421303   PMID:20442316   PMID:20501438   PMID:20852630   PMID:20942268   PMID:20945380   PMID:21063128   PMID:21092560   PMID:21113145   PMID:21118817   PMID:21179834   PMID:21180051  
PMID:21181362   PMID:21624330   PMID:21818553   PMID:21925583   PMID:22097274   PMID:22229265   PMID:22379036   PMID:22402332   PMID:22611921   PMID:22634325   PMID:22644775   PMID:22681889  
PMID:23027619   PMID:23382074   PMID:23398888   PMID:23506737   PMID:23585120   PMID:23818969   PMID:23870463   PMID:23918802   PMID:23992404   PMID:24225225   PMID:24342046   PMID:24375836  
PMID:24421392   PMID:24492282   PMID:24623306   PMID:24755082   PMID:24877090   PMID:25062485   PMID:25098198   PMID:25100604   PMID:25110868   PMID:25148934   PMID:25224220   PMID:25476526  
PMID:25609649   PMID:26514923   PMID:26875149   PMID:27194296   PMID:27220977   PMID:27239846   PMID:27458160   PMID:27458189   PMID:28100486   PMID:28701355   PMID:29225069   PMID:29257252  
PMID:29339068   PMID:29440459   PMID:30277501   PMID:31376136   PMID:32518215   PMID:33086033   PMID:33278012   PMID:33760331   PMID:35906072   PMID:36713029  


Genomics

Comparative Map Data
Jun
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85115,009,900 - 115,012,993 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5114,973,151 - 115,013,285 (-)EnsemblGRCr8
mRatBN7.25109,894,175 - 109,897,268 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5109,893,145 - 109,897,656 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5112,464,752 - 112,467,841 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05114,190,270 - 114,193,359 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05114,252,804 - 114,255,893 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05114,011,184 - 114,014,277 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5114,011,189 - 114,014,277 (-)Ensemblrn6Rnor6.0
Rnor_5.05117,957,730 - 117,960,823 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45115,358,166 - 115,361,259 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5108,510,040 - 108,513,133 (-)NCBICelera
RGSC_v3.15115,363,396 - 115,365,980 (-)NCBI
Cytogenetic Map5q33NCBI
JUN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38158,780,791 - 58,784,047 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl158,776,845 - 58,784,048 (-)Ensemblhg38GRCh38
GRCh37159,246,463 - 59,249,719 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36159,019,051 - 59,022,373 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34158,958,483 - 58,961,806NCBI
Celera157,530,296 - 57,533,618 (-)NCBICelera
Cytogenetic Map1p32.1NCBI
HuRef157,356,787 - 57,360,109 (-)NCBIHuRef
CHM1_1159,361,828 - 59,365,150 (-)NCBICHM1_1
T2T-CHM13v2.0158,659,236 - 58,662,492 (-)NCBIT2T-CHM13v2.0
Jun
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39494,937,273 - 94,940,459 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl494,937,271 - 94,940,459 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38495,049,036 - 95,052,222 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl495,049,034 - 95,052,222 (-)Ensemblmm10GRCm38
MGSCv37494,715,727 - 94,718,913 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36494,541,073 - 94,544,205 (-)NCBIMGSCv36mm8
Celera493,436,543 - 93,439,728 (-)NCBICelera
Cytogenetic Map4C5NCBI
cM Map443.34NCBI
Jun
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554641,107,598 - 1,110,326 (+)NCBIChiLan1.0ChiLan1.0
JUN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21168,063,962 - 168,067,574 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11167,218,036 - 167,219,853 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0158,042,794 - 58,045,536 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1159,747,129 - 59,750,446 (-)NCBIPanPan1.1PanPan1.1panPan2
JUN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1550,966,698 - 50,968,939 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha551,033,459 - 51,034,786 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0551,147,773 - 51,149,113 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl551,148,001 - 51,149,014 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1551,098,106 - 51,099,438 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0551,043,349 - 51,044,688 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0551,326,980 - 51,328,311 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Jun
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505872,379,192 - 72,381,903 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365223,035,346 - 3,036,350 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365223,034,364 - 3,037,632 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JUN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6153,685,682 - 153,687,636 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.16153,686,425 - 153,687,635 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26141,231,122 - 141,232,332 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JUN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12074,204,481 - 74,207,835 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2074,205,542 - 74,206,546 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603343,155,224 - 43,158,790 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Jun
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248621,538,455 - 1,539,426 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248621,537,886 - 1,540,633 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Jun
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1158,027,600 - 58,030,788 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Jun
20 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:34
Count of miRNA genes:30
Interacting mature miRNAs:34
Transcripts:ENSRNOT00000011731
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331796Thshl2Thyroid stimulating hormone level QTL 22.3blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)5102105698152749382Rat
1357396Bw44Body weight QTL 444.19body mass (VT:0001259)body weight (CMO:0000012)573779642118779642Rat
2303586Gluco52Glucose level QTL 522blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)5100826632145826632Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)544924861153890773Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)538207390136631402Rat
1298070Scl18Serum cholesterol level QTL 183.7blood LDL cholesterol amount (VT:0000181)calculated plasma low density lipoprotein cholesterol level (CMO:0001245)584630798129630798Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)599905133172190305Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)548523123134369373Rat
1298077Bp157Blood pressure QTL 157arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5114474223121056531Rat
2302381Bw84Body weight QTL 844.47body mass (VT:0001259)body mass index (BMI) (CMO:0000105)573779642118779642Rat
1357402Bw46Body weight QTL 464.47body mass (VT:0001259)body mass index (BMI) (CMO:0000105)573779642118779642Rat
7411582Foco3Food consumption QTL 37.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)592583776137583776Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)565089051166764498Rat
1598859Cm66Cardiac mass QTL 662heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)584630798129630798Rat
7207486Bss109Bone structure and strength QTL 109femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)5112142946157142946Rat
7207481Bss106Bone structure and strength QTL 1067.9femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5112142946157142946Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5110770739155770739Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)551657967166600247Rat
1549838Bss4Bone structure and strength QTL 49.2femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)5112142946157142946Rat
1582212Livw2Liver weight QTL 23.50.0004liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)5104018576124314782Rat
7411564Bw135Body weight QTL 1350.001body mass (VT:0001259)body weight gain (CMO:0000420)592583776137583776Rat
8657050Bw146Body weight QTL 14619.840.001body mass (VT:0001259)body weight gain (CMO:0000420)598972960143972960Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555124766172190305Rat
7411601Foco12Food consumption QTL 1219.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)592583776137583776Rat
2303618Vencon1Ventilatory control QTL 13.8respiration trait (VT:0001943)oxygen consumption (CMO:0002169)5100826632145826632Rat
2317056Wbc3White blood cell count QTL 32.510.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)5111236572156236572Rat
7394708Emca11Estrogen-induced mammary cancer QTL 11mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)573176602118176602Rat
1598846Bp293Blood pressure QTL 2933.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)584630798129630798Rat
7394710Emca12Estrogen-induced mammary cancer QTL 12mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)594034903139034903Rat
1598847Cm62Cardiac mass QTL 623.4heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5114131300159131300Rat
1358909Kidm25Kidney mass QTL 251.87kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)595062526133270832Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)560601597137492949Rat
7207488Bss110Bone structure and strength QTL 18.4femur strength trait (VT:0010010)femur stiffness (CMO:0001674)5112142946157142946Rat
7207491Bss112Bone structure and strength QTL 1127femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)5112142946157142946Rat
1600362Mcs19Mammary carcinoma susceptibility QTL 192.5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)582032155127032155Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)574335621156302135Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)536460764136631402Rat
1298086Bp156Blood pressure QTL 156arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)589369373134369373Rat
2306971Anxrr21Anxiety related response QTL 219.47fear/anxiety-related behavior trait (VT:1000241)number of entries into a discrete space in an experimental apparatus (CMO:0000960)570969494136328156Rat
1298089Scl14Serum cholesterol level QTL 145.80.0004blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5114131300159131300Rat
1358895Bp254Blood pressure QTL 2543.60.0003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)597492524133270832Rat
2312671Scl64Serum cholesterol level QTL 640.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)573779642118779642Rat
1358889Bp261Blood pressure QTL 2612.86arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)595062526133270832Rat
6903316Bw113Body weight QTL 11320.0103body mass (VT:0001259)body weight (CMO:0000012)592881678137881678Rat
1358187Emca1Estrogen-induced mammary cancer QTL 14.4mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)5104262817153890625Rat

Markers in Region
D5Mgh23  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr85115,013,533 - 115,013,661 (+)Marker Load Pipeline
mRatBN7.25109,897,808 - 109,897,936 (+)MAPPERmRatBN7.2
Rnor_6.05114,014,818 - 114,014,945NCBIRnor6.0
Rnor_5.05117,961,364 - 117,961,491UniSTSRnor5.0
RGSC_v3.45115,361,799 - 115,361,927RGDRGSC3.4
RGSC_v3.45115,361,800 - 115,361,927UniSTSRGSC3.4
Celera5108,513,674 - 108,513,801UniSTS
RGSC_v3.15115,367,025 - 115,367,153RGD
RH 3.4 Map5779.4UniSTS
RH 3.4 Map5779.4RGD
RH 2.0 Map5702.5RGD
Cytogenetic Map5q34.1UniSTS
D5Lev15  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25109,894,810 - 109,895,102 (+)MAPPERmRatBN7.2
Rnor_6.05114,011,820 - 114,012,111NCBIRnor6.0
Rnor_5.05117,958,366 - 117,958,657UniSTSRnor5.0
RGSC_v3.45115,358,802 - 115,359,093UniSTSRGSC3.4
Celera5108,510,676 - 108,510,967UniSTS
Cytogenetic Map5q34.1UniSTS
D5Arb17  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25109,897,663 - 109,897,907 (+)MAPPERmRatBN7.2
Rnor_6.05114,014,673 - 114,014,916NCBIRnor6.0
Rnor_5.05117,961,219 - 117,961,462UniSTSRnor5.0
RGSC_v3.45115,361,654 - 115,361,898RGDRGSC3.4
RGSC_v3.45115,361,655 - 115,361,898UniSTSRGSC3.4
Celera5108,513,529 - 108,513,772UniSTS
RGSC_v3.15115,366,880 - 115,367,124RGD
Cytogenetic Map5q34.1UniSTS
PMC129043P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25109,897,364 - 109,897,655 (+)MAPPERmRatBN7.2
Rnor_6.05114,014,374 - 114,014,664NCBIRnor6.0
Rnor_5.05117,960,920 - 117,961,210UniSTSRnor5.0
RGSC_v3.45115,361,356 - 115,361,646UniSTSRGSC3.4
Celera5108,513,230 - 108,513,520UniSTS
Cytogenetic Map5q34.1UniSTS
Jun  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25109,896,604 - 109,897,030 (+)MAPPERmRatBN7.2
Rnor_6.05114,013,614 - 114,014,039NCBIRnor6.0
Rnor_5.05117,960,160 - 117,960,585UniSTSRnor5.0
RGSC_v3.45115,360,596 - 115,361,021UniSTSRGSC3.4
Celera5108,512,470 - 108,512,895UniSTS
Cytogenetic Map5q34.1UniSTS
RH142347  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr85115,010,109 - 115,010,301 (+)Marker Load Pipeline
mRatBN7.25109,894,384 - 109,894,576 (+)MAPPERmRatBN7.2
Rnor_6.05114,011,394 - 114,011,585NCBIRnor6.0
Rnor_5.05117,957,940 - 117,958,131UniSTSRnor5.0
RGSC_v3.45115,358,376 - 115,358,567UniSTSRGSC3.4
Celera5108,510,250 - 108,510,441UniSTS
RH 3.4 Map5777.2UniSTS
Cytogenetic Map5q34.1UniSTS
PMC152658P3  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25109,894,800 - 109,895,148 (+)MAPPERmRatBN7.2
Rnor_6.05114,011,810 - 114,012,157NCBIRnor6.0
Rnor_5.05117,958,356 - 117,958,703UniSTSRnor5.0
RGSC_v3.45115,358,792 - 115,359,139UniSTSRGSC3.4
Celera5108,510,666 - 108,511,013UniSTS
Cytogenetic Map5q34.1UniSTS
AI407572  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25109,894,371 - 109,894,486 (+)MAPPERmRatBN7.2
Rnor_6.05114,011,381 - 114,011,495NCBIRnor6.0
Rnor_5.05117,957,927 - 117,958,041UniSTSRnor5.0
RGSC_v3.45115,358,363 - 115,358,477UniSTSRGSC3.4
Celera5108,510,237 - 108,510,351UniSTS
RH 3.4 Map5779.4UniSTS
Cytogenetic Map5q34.1UniSTS
PMC153970P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr85115,011,131 - 115,011,286 (+)Marker Load Pipeline
mRatBN7.25109,895,405 - 109,895,561 (+)MAPPERmRatBN7.2
Rnor_6.05114,012,415 - 114,012,570NCBIRnor6.0
Rnor_5.05117,958,961 - 117,959,116UniSTSRnor5.0
RGSC_v3.45115,359,397 - 115,359,552UniSTSRGSC3.4
Celera5108,511,271 - 108,511,426UniSTS
Cytogenetic Map5q34.1UniSTS
UniSTS:256946  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25109,895,884 - 109,896,151 (+)MAPPERmRatBN7.2
Rnor_6.05114,012,894 - 114,013,160NCBIRnor6.0
Rnor_5.05117,959,440 - 117,959,706UniSTSRnor5.0
RGSC_v3.45115,359,876 - 115,360,142UniSTSRGSC3.4
Celera5108,511,750 - 108,512,016UniSTS
Cytogenetic Map5q34.1UniSTS
PMC55707P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25109,895,405 - 109,896,410 (+)MAPPERmRatBN7.2
Rnor_6.05114,012,415 - 114,013,419NCBIRnor6.0
Rnor_5.05117,958,961 - 117,959,965UniSTSRnor5.0
RGSC_v3.45115,359,397 - 115,360,401UniSTSRGSC3.4
Celera5108,511,271 - 108,512,275UniSTS
Cytogenetic Map5q34.1UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000011731   ⟹   ENSRNOP00000011732
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5115,006,864 - 115,013,198 (-)Ensembl
mRatBN7.2 Ensembl5109,893,145 - 109,897,656 (-)Ensembl
Rnor_6.0 Ensembl5114,011,189 - 114,014,277 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000142314   ⟹   ENSRNOP00000105928
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5114,973,151 - 115,013,285 (-)Ensembl
RefSeq Acc Id: NM_021835   ⟹   NP_068607
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85115,009,900 - 115,012,993 (-)NCBI
mRatBN7.25109,894,175 - 109,897,268 (-)NCBI
Rnor_6.05114,011,184 - 114,014,277 (-)NCBI
Rnor_5.05117,957,730 - 117,960,823 (-)NCBI
RGSC_v3.45115,358,166 - 115,361,259 (-)RGD
Celera5108,510,040 - 108,513,133 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_068607 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH78738 (Get FASTA)   NCBI Sequence Viewer  
  CAA35041 (Get FASTA)   NCBI Sequence Viewer  
  CAA35084 (Get FASTA)   NCBI Sequence Viewer  
  EDL97766 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000011732
  ENSRNOP00000011732.1
GenBank Protein P17325 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_068607   ⟸   NM_021835
- UniProtKB: P17325 (UniProtKB/Swiss-Prot),   A6JRH4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000011732   ⟸   ENSRNOT00000011731
Ensembl Acc Id: ENSRNOP00000105928   ⟸   ENSRNOT00000142314
Protein Domains
bZIP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P17325-F1-model_v2 AlphaFold P17325 1-334 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693844
Promoter ID:EPDNEW_R4369
Type:multiple initiation site
Name:Jun_1
Description:Jun proto-oncogene, AP-1 transcription factor subunit
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05114,014,339 - 114,014,399EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2943 AgrOrtholog
BioCyc Gene G2FUF-40688 BioCyc
Ensembl Genes ENSRNOG00000026293 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000011731 ENTREZGENE
  ENSRNOT00000011731.4 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.5.170 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7124370 IMAGE-MGC_LOAD
InterPro AP-1_TF_bZIP UniProtKB/Swiss-Prot
  bZIP UniProtKB/Swiss-Prot
  bZIP_sf UniProtKB/Swiss-Prot
  JNK UniProtKB/Swiss-Prot
  Leuzip_Jun UniProtKB/Swiss-Prot
  TF_DNA-bd_sf UniProtKB/Swiss-Prot
KEGG Report rno:24516 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93192 IMAGE-MGC_LOAD
NCBI Gene 24516 ENTREZGENE
PANTHER JUN TRANSCRIPTION FACTOR-RELATED UniProtKB/Swiss-Prot
  PTHR11462:SF8 UniProtKB/Swiss-Prot
Pfam bZIP_1 UniProtKB/Swiss-Prot
  Jun UniProtKB/Swiss-Prot
PharmGKB JUN RGD
PhenoGen Jun PhenoGen
PRINTS LEUZIPPRJUN UniProtKB/Swiss-Prot
PROSITE BZIP UniProtKB/Swiss-Prot
  BZIP_BASIC UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000026293 RatGTEx
SMART BRLZ UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47454 UniProtKB/Swiss-Prot
  SSF57959 UniProtKB/Swiss-Prot
UniProt A6JRH4 ENTREZGENE, UniProtKB/TrEMBL
  JUN_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-05-11 Jun  Jun proto-oncogene, AP-1 transcription factor subunit  Jun  jun proto-oncogene  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-08-02 Jun  jun proto-oncogene  Jun  Jun oncogene  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-11-17 Jun  Jun oncogene    v-jun sarcoma virus 17 oncogene homolog (avian)  Name updated 1299863 APPROVED
2002-11-06 Jun  v-jun sarcoma virus 17 oncogene homolog (avian)    Avian sarcoma virus 17 (v-jun) oncogene homolog  Name updated 625702 APPROVED
2002-06-10 Jun  Avian sarcoma virus 17 (v-jun) oncogene homolog      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression highly expressed in lung tissue 628503
gene_function transcription factor 628503
gene_mutations_overexpression overexpression increases gene expression involved in fibrotic tissue remodeling, such as collagen and collagenase 628503
gene_process mediates cellular proliferation 628503
gene_product member of the activator protein-1 (AP-1) family of inducible nuclear proteins 628503
gene_regulation expression is increased by the treatment of amiodarone (AM), an iodinated benzofuran derivative and effective antidysrhythmic agent 628503
gene_regulation mRNA expression induced by estrogens 729283