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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2943
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Jun
Name: Jun proto-oncogene, AP-1 transcription factor subunit
Acc ID: CHEBI:34569
Term: Benzo[k]fluoranthene
Definition: A naphthalene that has formula C20H12.
Chemical ID: MESH:C022921
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Junincreases expressionISOJUN (Homo sapiens)6480464CTDbenzo(k)fluoranthene results in increased expression of JUN mRNAPMID:12799773 PMID:21635667
Junmultiple interactionsISOJUN (Homo sapiens)6480464CTDAcetylcysteine inhibits the reaction [benzo(k)fluoranthene results in increased expression of JUN mRNA]; SB 203580 inhibits the reaction [benzo(k)fluoranthene results in increased expression of JUN mRNA]PMID:21635667
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