GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Jun | increases expression | EXP | | 6480464 | CTD | Carbon Tetrachloride results in increased expression of JUN mRNA | PMID:8825185 PMID:9398495 | Jun | multiple interactions | EXP | | 6480464 | CTD | Acetylcysteine inhibits the reaction [Carbon Tetrachloride results in increased expression of JUN mRNA]; allyl sulfide inhibits the reaction [Carbon Tetrachloride results in increased expression of JUN mRNA]; Carbon Tetrachloride results in increased activity of [JUN protein binds to FOS protein]; Phenobarbital promotes the reaction [Carbon Tetrachloride results in increased expression of JUN mRNA]; pyridine promotes the reaction [Carbon Tetrachloride results in increased expression of JUN mRNA] | PMID:8825185 | Jun | increases expression | ISO | Jun (Mus musculus) | 6480464 | CTD | Carbon Tetrachloride results in increased expression of JUN mRNA; Carbon Tetrachloride results in increased expression of JUN protein | PMID:10915739 PMID:15056808 PMID:20589743 PMID:21354444 PMID:25827057 PMID:27339419 PMID:31919559 | Jun | multiple interactions | ISO | Jun (Mus musculus) | 6480464 | CTD | Carbon Tetrachloride promotes the reaction [JUN protein binds to CHKA promoter]; Carbon Tetrachloride results in increased phosphorylation of and results in increased localization of JUN protein; ferulic acid inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of and results in increased localization of JUN protein]; Plant Extracts inhibits the reaction [Carbon Tetrachloride results in increased expression of JUN protein] | PMID:17728180 PMID:20589743 PMID:21291945 | |
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