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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2943
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Jun
Name: Jun proto-oncogene, AP-1 transcription factor subunit
Acc ID: CHEBI:50648
Term: 9-cis-retinoic acid
Definition: A retinoic acid in which the exocyclic double bonds have 7E,9Z,11E,13E geometry.
Chemical ID: MESH:C103303
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Junmultiple interactionsISOJUN (Homo sapiens)6480464CTD[Alitretinoin co-treated with Tretinoin co-treated with Calcitriol] results in increased expression of JUN protein; Alitretinoin inhibits the reaction [TNF protein results in increased phosphorylation of JUN protein]PMID:19812349 PMID:8950452
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