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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2943 Species: Rattus norvegicus RGD Object: Gene Symbol: Jun Name: jun proto-oncogene

Acc ID: CHEBI:30563 Term: silicon dioxide Definition: A silicon oxide made up of linear triatomic molecules in which a silicon atom is covalently bonded to two oxygens. CasRN: 7631-86-9 Chemical ID: MESH:D012822

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases expression	ISO	RGD:10828	6480464	CTD	Silicon Dioxide results in increased expression of JUN mRNA	PMID:19073995
increases expression	ISO	RGD:734356	6480464	CTD	Silicon Dioxide results in increased expression of JUN mRNA	PMID:21540303