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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2943
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Jun
Name: Jun proto-oncogene, AP-1 transcription factor subunit
Acc ID: CHEBI:36560
Term: zinc oxide
Definition: A zinc molecular entity that has formula OZn.
Chemical ID: MESH:D015034
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Junaffects localizationISOJUN (Homo sapiens)6480464CTDZinc Oxide affects the localization of JUN proteinPMID:22166487
Junincreases expressionISOJun (Mus musculus)6480464CTDZinc Oxide results in increased expression of JUN proteinPMID:24368203
Junmultiple interactionsISOJUN (Homo sapiens)6480464CTDJUN protein affects the reaction [Zinc Oxide results in increased expression of ICAM1 protein]; NSC 23766 inhibits the reaction [Zinc Oxide results in increased phosphorylation of and results in increased activity of JUN protein]; pyrazolanthrone inhibits the reaction [Zinc Oxide affects the localization of JUN protein]; pyrazolanthrone inhibits the reaction [Zinc Oxide results in increased phosphorylation of and results in increased activity of JUN protein]; Zinc Oxide results in increased phosphorylation of and results in increased activity of JUN proteinPMID:22166487
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