GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Jun | multiple interactions | EXP | | 6480464 | CTD | [Curcumin co-treated with Manganese] inhibits the reaction [Kainic Acid results in increased expression of JUN mRNA]; [diacetylcurcumin co-treated with Manganese] inhibits the reaction [Kainic Acid results in increased expression of JUN mRNA]; NEPP11 compound inhibits the reaction [Manganese results in increased phosphorylation of JUN protein] | PMID:15342272 PMID:17827730 | Jun | decreases expression | ISO | JUN (Homo sapiens) | 6480464 | CTD | Manganese results in decreased expression of JUN protein | PMID:17043766 | Jun | multiple interactions | ISO | Jun (Mus musculus) | 6480464 | CTD | [Copper co-treated with Lead co-treated with Cadmium co-treated with Zinc co-treated with Mercury co-treated with Chromium co-treated with Manganese co-treated with Nickel] results in increased expression of JUN protein | PMID:28035397 | Jun | multiple interactions | ISO | JUN (Homo sapiens) | 6480464 | CTD | Manganese promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of [JUN protein binds to FOS protein]]; Manganese promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN protein]; Manganese promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of JUN protein] | PMID:22561169 | | ||||||||||||||||||||||
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