GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Jun | increases phosphorylation | EXP | | 6480464 | CTD | 1-Methyl-4-phenylpyridinium results in increased phosphorylation of JUN protein | PMID:18037221 | Jun | increases expression | ISO | JUN (Homo sapiens) | 6480464 | CTD | 1-Methyl-4-phenylpyridinium results in increased expression of JUN mRNA | PMID:14724376 | Jun | increases phosphorylation | ISO | JUN (Homo sapiens) | 6480464 | CTD | 1-Methyl-4-phenylpyridinium results in increased phosphorylation of JUN protein | PMID:20946892 | Jun | multiple interactions | ISO | JUN (Homo sapiens) | 6480464 | CTD | 1-Methyl-4-phenylpyridinium promotes the reaction [JUN protein binds to GADD45A promoter]; 8-phenyl-6a,7,8,9,9a,10-hexahydro-6H-isoindolo(5,6-g)quinoxaline-7,9-dione inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased phosphorylation of JUN protein]; JUN protein promotes the reaction [1-Methyl-4-phenylpyridinium results in increased expression of GADD45A protein]; Selegiline inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of JUN mRNA] | PMID:14724376 PMID:20946892 PMID:25469469 | |
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